Page last updated: 2024-09-03

pre 084 and phencyclidine

pre 084 has been researched along with phencyclidine in 4 studies

Compound Research Comparison

Studies
(pre 084)
Trials
(pre 084)
Recent Studies (post-2010)
(pre 084)
Studies
(phencyclidine)
Trials
(phencyclidine)
Recent Studies (post-2010) (phencyclidine)
11607328,2943877,796

Protein Interaction Comparison

ProteinTaxonomypre 084 (IC50)phencyclidine (IC50)
Glutamate receptor ionotropic, NMDA 1 Rattus norvegicus (Norway rat)0.1299
Lysosomal Pro-X carboxypeptidaseHomo sapiens (human)0.091
Glutamate receptor ionotropic, NMDA 2A Rattus norvegicus (Norway rat)0.1299
Glutamate receptor ionotropic, NMDA 2BRattus norvegicus (Norway rat)0.1299
Glutamate receptor ionotropic, NMDA 2CRattus norvegicus (Norway rat)0.1299
Glutamate receptor ionotropic, NMDA 1Homo sapiens (human)0.5563
Glutamate receptor ionotropic, NMDA 2AHomo sapiens (human)0.205
Glutamate receptor ionotropic, NMDA 2BHomo sapiens (human)1.2589
Glutamate receptor ionotropic, NMDA 2DRattus norvegicus (Norway rat)0.1299
Glutamate receptor ionotropic, NMDA 3BRattus norvegicus (Norway rat)0.1299
Sigma non-opioid intracellular receptor 1Rattus norvegicus (Norway rat)0.53
Glutamate receptor ionotropic, NMDA 3ARattus norvegicus (Norway rat)0.1299

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (75.00)18.2507
2000's1 (25.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Enache, LA; Gilardi, R; Mattson, MV; Moriarty, RM; Prakash, O; Zhao, L1
Cone, EJ; Dodge, AL; Gund, TM; Parish, DW; Shukla, K; Su, TP; Wu, XZ1
Maurice, T; Nabeshima, T; Parish, DW; Privat, A; Su, TP1
Cuevas, J; Guerrero, WR; Herrera, Y; Katnik, C; Pennypacker, KR1

Other Studies

4 other study(ies) available for pre 084 and phencyclidine

ArticleYear
Rigid phencyclidine analogues. Binding to the phencyclidine and sigma 1 receptors.
    Journal of medicinal chemistry, 1998, Feb-12, Volume: 41, Issue:4

    Topics: Animals; Brain; Crystallography, X-Ray; Indicators and Reagents; Ligands; Models, Molecular; Molecular Conformation; Molecular Structure; Phencyclidine; Radioligand Assay; Rats; Receptors, Phencyclidine; Receptors, sigma; Sigma-1 Receptor; Structure-Activity Relationship

1998
Sigma compounds derived from phencyclidine: identification of PRE-084, a new, selective sigma ligand.
    The Journal of pharmacology and experimental therapeutics, 1991, Volume: 259, Issue:2

    Topics: Animals; Guinea Pigs; Haloperidol; Male; Molecular Conformation; Morpholines; Phencyclidine; Receptors, Neurotransmitter; Receptors, Opioid; Receptors, Phencyclidine; Receptors, sigma; Structure-Activity Relationship

1991
PRE-084, a sigma selective PCP derivative, attenuates MK-801-induced impairment of learning in mice.
    Pharmacology, biochemistry, and behavior, 1994, Volume: 49, Issue:4

    Topics: Amnesia; Animals; Anti-Anxiety Agents; Avoidance Learning; Cholinergic Agents; Dizocilpine Maleate; Dose-Response Relationship, Drug; Haloperidol; Learning; Male; Maze Learning; Memory; Memory, Short-Term; Mice; Morpholines; Phencyclidine; Pyrimidines; Rats; Rats, Wistar; Receptors, sigma

1994
Sigma-1 receptor activation prevents intracellular calcium dysregulation in cortical neurons during in vitro ischemia.
    The Journal of pharmacology and experimental therapeutics, 2006, Volume: 319, Issue:3

    Topics: Analgesics, Opioid; Animals; Brain Ischemia; Calcium; Calcium Signaling; Cerebral Cortex; Cyclopentanes; Cytophotometry; Enzyme Inhibitors; Ethylenediamines; Female; Guanidines; Morpholines; Neurons; Pentazocine; Phencyclidine; Pregnancy; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, sigma; Sigma-1 Receptor; Sodium Azide; Sodium Channel Agonists; Tetrodotoxin

2006