pre 084 has been researched along with phencyclidine in 4 studies
| Studies (pre 084) | Trials (pre 084) | Recent Studies (post-2010) (pre 084) | Studies (phencyclidine) | Trials (phencyclidine) | Recent Studies (post-2010) (phencyclidine) |
|---|---|---|---|---|---|
| 116 | 0 | 73 | 28,294 | 387 | 7,796 |
| Protein | Taxonomy | pre 084 (IC50) | phencyclidine (IC50) |
|---|---|---|---|
| Glutamate receptor ionotropic, NMDA 1 | Rattus norvegicus (Norway rat) | 0.1299 | |
| Lysosomal Pro-X carboxypeptidase | Homo sapiens (human) | 0.091 | |
| Glutamate receptor ionotropic, NMDA 2A | Rattus norvegicus (Norway rat) | 0.1299 | |
| Glutamate receptor ionotropic, NMDA 2B | Rattus norvegicus (Norway rat) | 0.1299 | |
| Glutamate receptor ionotropic, NMDA 2C | Rattus norvegicus (Norway rat) | 0.1299 | |
| Glutamate receptor ionotropic, NMDA 1 | Homo sapiens (human) | 0.5563 | |
| Glutamate receptor ionotropic, NMDA 2A | Homo sapiens (human) | 0.205 | |
| Glutamate receptor ionotropic, NMDA 2B | Homo sapiens (human) | 1.2589 | |
| Glutamate receptor ionotropic, NMDA 2D | Rattus norvegicus (Norway rat) | 0.1299 | |
| Glutamate receptor ionotropic, NMDA 3B | Rattus norvegicus (Norway rat) | 0.1299 | |
| Sigma non-opioid intracellular receptor 1 | Rattus norvegicus (Norway rat) | 0.53 | |
| Glutamate receptor ionotropic, NMDA 3A | Rattus norvegicus (Norway rat) | 0.1299 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (75.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Enache, LA; Gilardi, R; Mattson, MV; Moriarty, RM; Prakash, O; Zhao, L | 1 |
| Cone, EJ; Dodge, AL; Gund, TM; Parish, DW; Shukla, K; Su, TP; Wu, XZ | 1 |
| Maurice, T; Nabeshima, T; Parish, DW; Privat, A; Su, TP | 1 |
| Cuevas, J; Guerrero, WR; Herrera, Y; Katnik, C; Pennypacker, KR | 1 |
4 other study(ies) available for pre 084 and phencyclidine
| Article | Year |
|---|---|
Rigid phencyclidine analogues. Binding to the phencyclidine and sigma 1 receptors.
Topics: Animals; Brain; Crystallography, X-Ray; Indicators and Reagents; Ligands; Models, Molecular; Molecular Conformation; Molecular Structure; Phencyclidine; Radioligand Assay; Rats; Receptors, Phencyclidine; Receptors, sigma; Sigma-1 Receptor; Structure-Activity Relationship | 1998 |
Sigma compounds derived from phencyclidine: identification of PRE-084, a new, selective sigma ligand.
Topics: Animals; Guinea Pigs; Haloperidol; Male; Molecular Conformation; Morpholines; Phencyclidine; Receptors, Neurotransmitter; Receptors, Opioid; Receptors, Phencyclidine; Receptors, sigma; Structure-Activity Relationship | 1991 |
PRE-084, a sigma selective PCP derivative, attenuates MK-801-induced impairment of learning in mice.
Topics: Amnesia; Animals; Anti-Anxiety Agents; Avoidance Learning; Cholinergic Agents; Dizocilpine Maleate; Dose-Response Relationship, Drug; Haloperidol; Learning; Male; Maze Learning; Memory; Memory, Short-Term; Mice; Morpholines; Phencyclidine; Pyrimidines; Rats; Rats, Wistar; Receptors, sigma | 1994 |
Sigma-1 receptor activation prevents intracellular calcium dysregulation in cortical neurons during in vitro ischemia.
Topics: Analgesics, Opioid; Animals; Brain Ischemia; Calcium; Calcium Signaling; Cerebral Cortex; Cyclopentanes; Cytophotometry; Enzyme Inhibitors; Ethylenediamines; Female; Guanidines; Morpholines; Neurons; Pentazocine; Phencyclidine; Pregnancy; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, sigma; Sigma-1 Receptor; Sodium Azide; Sodium Channel Agonists; Tetrodotoxin | 2006 |