Page last updated: 2024-09-03

pre 084 and naloxone

pre 084 has been researched along with naloxone in 2 studies

Compound Research Comparison

Studies (pre 084)	Trials (pre 084)	Recent Studies (post-2010) (pre 084)	Studies (naloxone)	Trials (naloxone)	Recent Studies (post-2010) (naloxone)
116	0	73	20,134	1,257	3,321

Protein Interaction Comparison

Protein	Taxonomy	naloxone (IC50)
Cytochrome P450 2D6	Homo sapiens (human)	2
Delta-type opioid receptor	Mus musculus (house mouse)	0.043
Delta-type opioid receptor	Rattus norvegicus (Norway rat)	0.0219
Mu-type opioid receptor	Rattus norvegicus (Norway rat)	0.0019
Kappa-type opioid receptor	Rattus norvegicus (Norway rat)	0.0019
Mu-type opioid receptor	Homo sapiens (human)	0.0397
Delta-type opioid receptor	Homo sapiens (human)	0.1896
Kappa-type opioid receptor	Cavia porcellus (domestic guinea pig)	0.05
Kappa-type opioid receptor	Homo sapiens (human)	0.0795
Mu-type opioid receptor	Mus musculus (house mouse)	0.0154
Mu-type opioid receptor	Cavia porcellus (domestic guinea pig)	0.0089
Beta-2 adrenergic receptor	Cavia porcellus (domestic guinea pig)	0.0055

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (50.00)	29.6817
2010's	1 (50.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Baeyens, JM; Cendán, CM; Cobos, EJ; Del Pozo, E; Entrena, JM; Nieto, FR	1
Baeyens, JM; Cikes, D; Cobos, EJ; Cronin, SJ; González-Cano, R; Montilla-García, A; Penninger, JM; Ruiz-Cantero, MC; Sánchez-Fernández, C; Tejada, MA; Vela, JM	1

Other Studies

2 other study(ies) available for pre 084 and naloxone

Article	Year
Antagonism by haloperidol and its metabolites of mechanical hypersensitivity induced by intraplantar capsaicin in mice: role of sigma-1 receptors. Psychopharmacology, 2009, Volume: 205, Issue:1 Topics: Analysis of Variance; Animals; Brain; Capsaicin; Disease Models, Animal; Dopamine Antagonists; Dose-Response Relationship, Drug; Female; Haloperidol; Hyperalgesia; Mice; Morpholines; Motor Activity; Naloxone; Narcotic Antagonists; Pain; Pain Measurement; Pain Threshold; Pentazocine; Physical Stimulation; Protein Binding; Radioligand Assay; Reaction Time; Receptors, sigma; Rotarod Performance Test; Sigma-1 Receptor; Tritium	2009
Sigma-1 receptors control immune-driven peripheral opioid analgesia during inflammation in mice. Proceedings of the National Academy of Sciences of the United States of America, 2017, 08-01, Volume: 114, Issue:31 Topics: Analgesia; Analgesics, Opioid; Animals; Antigens, Ly; Carrageenan; Female; Inflammation; Macrophages; Mice; Morpholines; Naloxone; Narcotic Antagonists; Neutrophils; Oligopeptides; Pain; Piperazines; Pro-Opiomelanocortin; Pyrazoles; Quaternary Ammonium Compounds; Receptors, sigma; Sigma-1 Receptor	2017

Article

Year

Antagonism by haloperidol and its metabolites of mechanical hypersensitivity induced by intraplantar capsaicin in mice: role of sigma-1 receptors.

Psychopharmacology, 2009, Volume: 205, Issue:1

Topics: Analysis of Variance; Animals; Brain; Capsaicin; Disease Models, Animal; Dopamine Antagonists; Dose-Response Relationship, Drug; Female; Haloperidol; Hyperalgesia; Mice; Morpholines; Motor Activity; Naloxone; Narcotic Antagonists; Pain; Pain Measurement; Pain Threshold; Pentazocine; Physical Stimulation; Protein Binding; Radioligand Assay; Reaction Time; Receptors, sigma; Rotarod Performance Test; Sigma-1 Receptor; Tritium

2009

Sigma-1 receptors control immune-driven peripheral opioid analgesia during inflammation in mice.

Proceedings of the National Academy of Sciences of the United States of America, 2017, 08-01, Volume: 114, Issue:31

Topics: Analgesia; Analgesics, Opioid; Animals; Antigens, Ly; Carrageenan; Female; Inflammation; Macrophages; Mice; Morpholines; Naloxone; Narcotic Antagonists; Neutrophils; Oligopeptides; Pain; Piperazines; Pro-Opiomelanocortin; Pyrazoles; Quaternary Ammonium Compounds; Receptors, sigma; Sigma-1 Receptor

2017