pre 084 has been researched along with glutamic acid in 3 studies
| Studies (pre 084) | Trials (pre 084) | Recent Studies (post-2010) (pre 084) | Studies (glutamic acid) | Trials (glutamic acid) | Recent Studies (post-2010) (glutamic acid) |
|---|---|---|---|---|---|
| 116 | 0 | 73 | 41,757 | 452 | 12,876 |
| Protein | Taxonomy | pre 084 (IC50) | glutamic acid (IC50) |
|---|---|---|---|
| Chain A, GLUTAMATE RECEPTOR SUBUNIT 2 | Rattus norvegicus (Norway rat) | 0.821 | |
| Chain A, Glutamate Receptor Subunit 2 | Rattus norvegicus (Norway rat) | 0.821 | |
| Chain B, Glutamate Receptor Subunit 2 | Rattus norvegicus (Norway rat) | 0.821 | |
| Metabotropic glutamate receptor 8 | Homo sapiens (human) | 0.0057 | |
| Glutamate receptor ionotropic, NMDA 2D | Homo sapiens (human) | 0.07 | |
| Glutamate receptor ionotropic, NMDA 3B | Homo sapiens (human) | 0.07 | |
| Glutamate receptor 1 | Rattus norvegicus (Norway rat) | 0.5885 | |
| Glutamate receptor 2 | Rattus norvegicus (Norway rat) | 0.5885 | |
| Glutamate receptor 3 | Rattus norvegicus (Norway rat) | 0.5885 | |
| Glutamate receptor 4 | Rattus norvegicus (Norway rat) | 0.5885 | |
| Glutamate receptor ionotropic, kainate 1 | Rattus norvegicus (Norway rat) | 0.38 | |
| Glutamate receptor ionotropic, NMDA 1 | Rattus norvegicus (Norway rat) | 0.1533 | |
| Glutamate receptor ionotropic, kainate 2 | Rattus norvegicus (Norway rat) | 0.38 | |
| Glutamate receptor 1 | Homo sapiens (human) | 0.613 | |
| Glutamate receptor 2 | Homo sapiens (human) | 0.613 | |
| Glutamate receptor 3 | Homo sapiens (human) | 0.613 | |
| Glutamate receptor ionotropic, kainate 3 | Rattus norvegicus (Norway rat) | 0.38 | |
| Excitatory amino acid transporter 1 | Homo sapiens (human) | 207 | |
| Glutamate receptor 4 | Homo sapiens (human) | 0.613 | |
| Glutamate receptor ionotropic, NMDA 2A | Rattus norvegicus (Norway rat) | 0.1533 | |
| Glutamate receptor ionotropic, NMDA 2B | Rattus norvegicus (Norway rat) | 0.1533 | |
| Glutamate receptor ionotropic, NMDA 2C | Rattus norvegicus (Norway rat) | 0.1533 | |
| Glutamate receptor ionotropic, kainate 4 | Rattus norvegicus (Norway rat) | 0.38 | |
| Glutamate receptor ionotropic, NMDA 1 | Homo sapiens (human) | 0.07 | |
| Glutamate receptor ionotropic, NMDA 2A | Homo sapiens (human) | 0.07 | |
| Glutamate receptor ionotropic, NMDA 2B | Homo sapiens (human) | 0.07 | |
| Glutamate receptor ionotropic, NMDA 2C | Homo sapiens (human) | 0.07 | |
| Glutamate receptor ionotropic, NMDA 2D | Rattus norvegicus (Norway rat) | 0.1533 | |
| Glutamate receptor ionotropic, kainate 5 | Rattus norvegicus (Norway rat) | 0.38 | |
| Glutamate receptor ionotropic, NMDA 3A | Homo sapiens (human) | 0.07 | |
| Glutamate receptor ionotropic, NMDA 3B | Rattus norvegicus (Norway rat) | 0.1533 | |
| Glutamate receptor ionotropic, NMDA 3A | Rattus norvegicus (Norway rat) | 0.1533 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chou, YC; Liao, JF; Liou, KT; Shen, YC; Wang, WY; Wang, YH; Yen, JC | 1 |
| Casas, C; Guzmán-Lenis, MS; Navarro, X | 1 |
| Griesmaier, E; Gross, M; Hermann, M; Keller, M; Kiechl-Kohlendorfer, U; Neubauer, V; Posod, A; Urbanek, M; Wegleiter, K | 1 |
3 other study(ies) available for pre 084 and glutamic acid
| Article | Year |
|---|---|
Dimemorfan protects rats against ischemic stroke through activation of sigma-1 receptor-mediated mechanisms by decreasing glutamate accumulation.
Topics: Analysis of Variance; Animals; Brain Infarction; Brain Ischemia; Chemokine CCL2; Disease Models, Animal; Dose-Response Relationship, Drug; Gene Expression Regulation; Glutamic Acid; Lipid Peroxidation; Male; Morphinans; Morpholines; NF-kappaB-Inducing Kinase; Nitric Oxide Synthase; Peroxidase; Protein Serine-Threonine Kinases; Rats; Rats, Long-Evans; Receptors, sigma; Reperfusion Injury; Sigma-1 Receptor; Signal Transduction; STAT1 Transcription Factor | 2008 |
Selective sigma receptor agonist 2-(4-morpholinethyl)1-phenylcyclohexanecarboxylate (PRE084) promotes neuroprotection and neurite elongation through protein kinase C (PKC) signaling on motoneurons.
Topics: Animals; Benzophenanthridines; Cell Survival; Dose-Response Relationship, Drug; Enzyme Inhibitors; Ganglia, Spinal; Glutamic Acid; In Vitro Techniques; Morpholines; Motor Neurons; Neurites; Neurons; Neuroprotective Agents; Neurotoxins; Piperazines; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, sigma; Signal Transduction; Spinal Cord | 2009 |
Neuroprotective effects of the sigma-1 receptor ligand PRE-084 against excitotoxic perinatal brain injury in newborn mice.
Topics: Animals; Animals, Newborn; Apoptosis; Brain Injuries; Excitatory Amino Acids; Glutamic Acid; Immunohistochemistry; In Situ Nick-End Labeling; Ligands; Mice; Microscopy, Confocal; Morpholines; Neurons; Neuroprotective Agents; Real-Time Polymerase Chain Reaction; Receptors, sigma; Sigma-1 Receptor | 2012 |