pre 084 has been researched along with enkephalin, ala(2)-mephe(4)-gly(5)- in 1 studies
| Studies (pre 084) | Trials (pre 084) | Recent Studies (post-2010) (pre 084) | Studies (enkephalin, ala(2)-mephe(4)-gly(5)-) | Trials (enkephalin, ala(2)-mephe(4)-gly(5)-) | Recent Studies (post-2010) (enkephalin, ala(2)-mephe(4)-gly(5)-) |
|---|---|---|---|---|---|
| 116 | 0 | 73 | 151 | 0 | 71 |
| Protein | Taxonomy | pre 084 (IC50) | enkephalin, ala(2)-mephe(4)-gly(5)- (IC50) |
|---|---|---|---|
| Muscarinic acetylcholine receptor M1 | Rattus norvegicus (Norway rat) | 0.003 | |
| Muscarinic acetylcholine receptor M3 | Rattus norvegicus (Norway rat) | 0.003 | |
| Muscarinic acetylcholine receptor M4 | Rattus norvegicus (Norway rat) | 0.003 | |
| Muscarinic acetylcholine receptor M5 | Rattus norvegicus (Norway rat) | 0.003 | |
| Muscarinic acetylcholine receptor M2 | Rattus norvegicus (Norway rat) | 0.003 | |
| Delta-type opioid receptor | Mus musculus (house mouse) | 1.2415 | |
| Mu-type opioid receptor | Rattus norvegicus (Norway rat) | 0.0132 | |
| Mu-type opioid receptor | Homo sapiens (human) | 0.004 | |
| Delta-type opioid receptor | Homo sapiens (human) | 0.0014 | |
| Mu-type opioid receptor | Mus musculus (house mouse) | 0.0048 | |
| Mu-type opioid receptor | Cavia porcellus (domestic guinea pig) | 0.0283 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Belyakov, S; Dambrova, M; Kazoka, H; Kuznecovs, J; Lebedev, A; Liepinsh, E; Mishnev, A; Orlova, N; Ponomaryov, Y; Vavers, E; Veinberg, G; Vikainis, S; Vilskersts, R; Vorona, M; Zvejniece, L | 1 |
1 other study(ies) available for pre 084 and enkephalin, ala(2)-mephe(4)-gly(5)-
| Article | Year |
|---|---|
Synthesis and biological evaluation of 2-(5-methyl-4-phenyl-2-oxopyrrolidin-1-yl)-acetamide stereoisomers as novel positive allosteric modulators of sigma-1 receptor.
Topics: Acetamides; Allosteric Regulation; Animals; Rats; Rats, Wistar; Receptors, sigma; Sigma-1 Receptor; Stereoisomerism; Structure-Activity Relationship | 2013 |