pre 084 has been researched along with carbetapentane in 9 studies
Studies (pre 084) | Trials (pre 084) | Recent Studies (post-2010) (pre 084) | Studies (carbetapentane) | Trials (carbetapentane) | Recent Studies (post-2010) (carbetapentane) |
---|---|---|---|---|---|
116 | 0 | 73 | 73 | 1 | 23 |
Protein | Taxonomy | pre 084 (IC50) | carbetapentane (IC50) |
---|---|---|---|
Solute carrier family 22 member 1 | Homo sapiens (human) | 1.55 |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 2 (22.22) | 18.2507 |
2000's | 6 (66.67) | 29.6817 |
2010's | 1 (11.11) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Calderon, SN; Gutkind, JS; Heller, B; Izenwasser, S; Mattson, MV; Newman, AH; Su, TP | 1 |
Enache, LA; Gilardi, R; Mattson, MV; Moriarty, RM; Prakash, O; Zhao, L | 1 |
Hoffman, BT; Katz, JL; Kopajtic, T; Newman, AH | 1 |
Bowen, WD; Cao, J; George, C; Husbands, SM; Katz, JL; Kopajtic, T; Kulkarni, SS; Newman, AH; Williams, W | 1 |
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
Cuevas, J; Guerrero, WR; Herrera, Y; Katnik, C; Pennypacker, KR | 1 |
Beitz, AJ; Han, HJ; Kim, HW; Kim, KW; Kwon, YB; Lee, JH; Roh, DH; Seo, HS; Yoon, SY | 2 |
Baeyens, JM; Cobos, EJ; Entrena, JM; González-Cano, R; Nieto, FR; Sánchez-Fernández, C; Yeste, S | 1 |
9 other study(ies) available for pre 084 and carbetapentane
Article | Year |
---|---|
Novel 1-phenylcycloalkanecarboxylic acid derivatives are potent and selective sigma 1 ligands.
Topics: Animals; Anticonvulsants; Antitussive Agents; Binding Sites; Cyclopentanes; In Vitro Techniques; Male; Myocardial Ischemia; Rats; Rats, Sprague-Dawley; Receptors, sigma; Structure-Activity Relationship | 1994 |
Rigid phencyclidine analogues. Binding to the phencyclidine and sigma 1 receptors.
Topics: Animals; Brain; Crystallography, X-Ray; Indicators and Reagents; Ligands; Models, Molecular; Molecular Conformation; Molecular Structure; Phencyclidine; Radioligand Assay; Rats; Receptors, Phencyclidine; Receptors, sigma; Sigma-1 Receptor; Structure-Activity Relationship | 1998 |
2D QSAR modeling and preliminary database searching for dopamine transporter inhibitors using genetic algorithm variable selection of Molconn Z descriptors.
Topics: Algorithms; Binding, Competitive; Carrier Proteins; Databases, Factual; Dopamine; Dopamine Plasma Membrane Transport Proteins; Ligands; Membrane Glycoproteins; Membrane Transport Proteins; Models, Molecular; Nerve Tissue Proteins; Quantitative Structure-Activity Relationship; Radioligand Assay; Reproducibility of Results; Software | 2000 |
Dual probes for the dopamine transporter and sigma1 receptors: novel piperazinyl alkyl-bis(4'-fluorophenyl)amine analogues as potential cocaine-abuse therapeutic agents.
Topics: Animals; Binding, Competitive; Brain; Cocaine-Related Disorders; Crystallography, X-Ray; Dopamine; Dopamine Plasma Membrane Transport Proteins; In Vitro Techniques; Membrane Glycoproteins; Membrane Transport Proteins; Models, Molecular; Nerve Tissue Proteins; Piperazines; Radioligand Assay; Rats; Receptors, sigma; Structure-Activity Relationship | 2003 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Sigma-1 receptor activation prevents intracellular calcium dysregulation in cortical neurons during in vitro ischemia.
Topics: Analgesics, Opioid; Animals; Brain Ischemia; Calcium; Calcium Signaling; Cerebral Cortex; Cyclopentanes; Cytophotometry; Enzyme Inhibitors; Ethylenediamines; Female; Guanidines; Morpholines; Neurons; Pentazocine; Phencyclidine; Pregnancy; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, sigma; Sigma-1 Receptor; Sodium Azide; Sodium Channel Agonists; Tetrodotoxin | 2006 |
Activation of the spinal sigma-1 receptor enhances NMDA-induced pain via PKC- and PKA-dependent phosphorylation of the NR1 subunit in mice.
Topics: Animals; Behavior, Animal; Blotting, Western; Cyclic AMP-Dependent Protein Kinases; Cyclopentanes; Disease Models, Animal; Dose-Response Relationship, Drug; Ethylenediamines; Immunohistochemistry; Injections, Spinal; Male; Mice; Mice, Inbred ICR; Morpholines; N-Methylaspartate; Pain; Pain Measurement; Phosphorylation; Posterior Horn Cells; Protein Kinase C; Receptors, N-Methyl-D-Aspartate; Receptors, sigma; Serine; Sigma-1 Receptor; Signal Processing, Computer-Assisted; Signal Transduction; Spinal Cord; Time Factors | 2008 |
Intrathecal administration of sigma-1 receptor agonists facilitates nociception: involvement of a protein kinase C-dependent pathway.
Topics: Animals; Antitussive Agents; Calcium Signaling; Cyclopentanes; Disease Models, Animal; Enzyme Inhibitors; Ethylenediamines; Inflammation Mediators; Injections, Spinal; Male; Mice; Mice, Inbred ICR; Morpholines; Nociceptors; Pain; Pain Measurement; Pain Threshold; Posterior Horn Cells; Protein Kinase C; Proto-Oncogene Proteins c-fos; Receptors, sigma; Sigma-1 Receptor; Signal Transduction; Spinal Cord | 2008 |
Sigma-1 Receptor Agonism Promotes Mechanical Allodynia After Priming the Nociceptive System with Capsaicin.
Topics: Animals; Capsaicin; Cyclopentanes; Disease Models, Animal; Hyperalgesia; Liver; Male; Mice; Morpholines; Nociception; Pain Measurement; Pain Threshold; Pentazocine; Receptors, sigma; Sigma-1 Receptor | 2016 |