Compounds > pre 084

Page last updated: 2024-09-03

pre 084 and carbetapentane

pre 084 has been researched along with carbetapentane in 9 studies

Compound Research Comparison

Studies (pre 084)	Trials (pre 084)	Recent Studies (post-2010) (pre 084)	Studies (carbetapentane)	Trials (carbetapentane)	Recent Studies (post-2010) (carbetapentane)
116	0	73	73	1	23

Protein Interaction Comparison

Protein	Taxonomy	pre 084 (IC50)	carbetapentane (IC50)
Solute carrier family 22 member 1	Homo sapiens (human)		1.55

Research

Studies (9)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	2 (22.22)	18.2507
2000's	6 (66.67)	29.6817
2010's	1 (11.11)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Calderon, SN; Gutkind, JS; Heller, B; Izenwasser, S; Mattson, MV; Newman, AH; Su, TP	1
Enache, LA; Gilardi, R; Mattson, MV; Moriarty, RM; Prakash, O; Zhao, L	1
Hoffman, BT; Katz, JL; Kopajtic, T; Newman, AH	1
Bowen, WD; Cao, J; George, C; Husbands, SM; Katz, JL; Kopajtic, T; Kulkarni, SS; Newman, AH; Williams, W	1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J	1
Cuevas, J; Guerrero, WR; Herrera, Y; Katnik, C; Pennypacker, KR	1
Beitz, AJ; Han, HJ; Kim, HW; Kim, KW; Kwon, YB; Lee, JH; Roh, DH; Seo, HS; Yoon, SY	2
Baeyens, JM; Cobos, EJ; Entrena, JM; González-Cano, R; Nieto, FR; Sánchez-Fernández, C; Yeste, S	1

Other Studies

9 other study(ies) available for pre 084 and carbetapentane

Article	Year
Novel 1-phenylcycloalkanecarboxylic acid derivatives are potent and selective sigma 1 ligands. Journal of medicinal chemistry, 1994, Jul-22, Volume: 37, Issue:15 Topics: Animals; Anticonvulsants; Antitussive Agents; Binding Sites; Cyclopentanes; In Vitro Techniques; Male; Myocardial Ischemia; Rats; Rats, Sprague-Dawley; Receptors, sigma; Structure-Activity Relationship	1994
Rigid phencyclidine analogues. Binding to the phencyclidine and sigma 1 receptors. Journal of medicinal chemistry, 1998, Feb-12, Volume: 41, Issue:4 Topics: Animals; Brain; Crystallography, X-Ray; Indicators and Reagents; Ligands; Models, Molecular; Molecular Conformation; Molecular Structure; Phencyclidine; Radioligand Assay; Rats; Receptors, Phencyclidine; Receptors, sigma; Sigma-1 Receptor; Structure-Activity Relationship	1998
2D QSAR modeling and preliminary database searching for dopamine transporter inhibitors using genetic algorithm variable selection of Molconn Z descriptors. Journal of medicinal chemistry, 2000, Nov-02, Volume: 43, Issue:22 Topics: Algorithms; Binding, Competitive; Carrier Proteins; Databases, Factual; Dopamine; Dopamine Plasma Membrane Transport Proteins; Ligands; Membrane Glycoproteins; Membrane Transport Proteins; Models, Molecular; Nerve Tissue Proteins; Quantitative Structure-Activity Relationship; Radioligand Assay; Reproducibility of Results; Software	2000
Dual probes for the dopamine transporter and sigma1 receptors: novel piperazinyl alkyl-bis(4'-fluorophenyl)amine analogues as potential cocaine-abuse therapeutic agents. Journal of medicinal chemistry, 2003, Jun-19, Volume: 46, Issue:13 Topics: Animals; Binding, Competitive; Brain; Cocaine-Related Disorders; Crystallography, X-Ray; Dopamine; Dopamine Plasma Membrane Transport Proteins; In Vitro Techniques; Membrane Glycoproteins; Membrane Transport Proteins; Models, Molecular; Nerve Tissue Proteins; Piperazines; Radioligand Assay; Rats; Receptors, sigma; Structure-Activity Relationship	2003
Chemical genetics reveals a complex functional ground state of neural stem cells. Nature chemical biology, 2007, Volume: 3, Issue:5 Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells	2007
Sigma-1 receptor activation prevents intracellular calcium dysregulation in cortical neurons during in vitro ischemia. The Journal of pharmacology and experimental therapeutics, 2006, Volume: 319, Issue:3 Topics: Analgesics, Opioid; Animals; Brain Ischemia; Calcium; Calcium Signaling; Cerebral Cortex; Cyclopentanes; Cytophotometry; Enzyme Inhibitors; Ethylenediamines; Female; Guanidines; Morpholines; Neurons; Pentazocine; Phencyclidine; Pregnancy; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, sigma; Sigma-1 Receptor; Sodium Azide; Sodium Channel Agonists; Tetrodotoxin	2006
Activation of the spinal sigma-1 receptor enhances NMDA-induced pain via PKC- and PKA-dependent phosphorylation of the NR1 subunit in mice. British journal of pharmacology, 2008, Volume: 154, Issue:5 Topics: Animals; Behavior, Animal; Blotting, Western; Cyclic AMP-Dependent Protein Kinases; Cyclopentanes; Disease Models, Animal; Dose-Response Relationship, Drug; Ethylenediamines; Immunohistochemistry; Injections, Spinal; Male; Mice; Mice, Inbred ICR; Morpholines; N-Methylaspartate; Pain; Pain Measurement; Phosphorylation; Posterior Horn Cells; Protein Kinase C; Receptors, N-Methyl-D-Aspartate; Receptors, sigma; Serine; Sigma-1 Receptor; Signal Processing, Computer-Assisted; Signal Transduction; Spinal Cord; Time Factors	2008
Intrathecal administration of sigma-1 receptor agonists facilitates nociception: involvement of a protein kinase C-dependent pathway. Journal of neuroscience research, 2008, Volume: 86, Issue:16 Topics: Animals; Antitussive Agents; Calcium Signaling; Cyclopentanes; Disease Models, Animal; Enzyme Inhibitors; Ethylenediamines; Inflammation Mediators; Injections, Spinal; Male; Mice; Mice, Inbred ICR; Morpholines; Nociceptors; Pain; Pain Measurement; Pain Threshold; Posterior Horn Cells; Protein Kinase C; Proto-Oncogene Proteins c-fos; Receptors, sigma; Sigma-1 Receptor; Signal Transduction; Spinal Cord	2008
Sigma-1 Receptor Agonism Promotes Mechanical Allodynia After Priming the Nociceptive System with Capsaicin. Scientific reports, 2016, 11-25, Volume: 6 Topics: Animals; Capsaicin; Cyclopentanes; Disease Models, Animal; Hyperalgesia; Liver; Male; Mice; Morpholines; Nociception; Pain Measurement; Pain Threshold; Pentazocine; Receptors, sigma; Sigma-1 Receptor	2016