pre 084 has been researched along with bd 1047 in 21 studies
| Studies (pre 084) | Trials (pre 084) | Recent Studies (post-2010) (pre 084) | Studies (bd 1047) | Trials (bd 1047) | Recent Studies (post-2010) (bd 1047) |
|---|---|---|---|---|---|
| 116 | 0 | 73 | 118 | 0 | 54 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 10 (47.62) | 29.6817 |
| 2010's | 10 (47.62) | 24.3611 |
| 2020's | 1 (4.76) | 2.80 |
| Authors | Studies |
|---|---|
| Dubinett, SM; Gardner, B; Roth, MD; Sharma, S; Tashkin, DP; Zhu, LX | 1 |
| Bucolo, C; Drago, F | 1 |
| Baeyens, JM; Cobos, EJ; Del Pozo, E | 1 |
| Bucolo, C; Drago, F; Lin, LR; Reddy, VN | 1 |
| Cuevas, J; Guerrero, WR; Herrera, Y; Katnik, C; Pennypacker, KR | 1 |
| Egashira, N; Fujiwara, M; Harada, S; Iwasaki, K; Matsushita, M; Mishima, K; Nishimura, R; Okuno, R; Orito, K | 1 |
| Bernardini, R; Bucolo, C; Calvagna, R; Cantarella, G; Clementi, S; Di Benedetto, G; Fiore, L; Lempereur, L; Pavone, P; Pezzino, S | 1 |
| Beitz, AJ; Han, HJ; Kim, HW; Kim, KW; Kwon, YB; Lee, JH; Roh, DH; Seo, HS; Yoon, SY | 2 |
| Baeyens, JM; Cendán, CM; Cobos, EJ; Del Pozo, E; Entrena, JM; Gris, G; Nieto, FR; Zamanillo, D | 1 |
| Garcés-Ramírez, L; Green, JL; Hiranita, T; Katz, JL; Kopajtic, TA; McCurdy, CR; Mereu, M; Mesangeau, C; Narayanan, S; Tanda, G; Thomas, AM | 1 |
| Bhutada, PS; Chaware, P; Dixit, PV; Ghodki, YR; Jain, KS; Mundhada, YR; Umathe, SN | 1 |
| Beitz, AJ; Choi, HS; Choi, SR; Han, HJ; Kang, SY; Kwon, SG; Lee, JH; Moon, JY; Roh, DH; Yoon, SY | 2 |
| Beitz, AJ; Choi, HS; Choi, SR; Han, HJ; Kang, SY; Kwon, SG; Lee, JH; Moon, JY; Oh, SB; Roh, DH; Yoon, SY | 1 |
| Ahlskog, N; Beique, JC; Bergeron, R; Biscaro, D; Hristova, E; Nassrallah, W; Ngsee, JK; Pabba, M; Snyder, M; Wong, AY | 1 |
| Beitz, AJ; Choi, HS; Choi, SR; Han, HJ; Kang, SY; Kim, HW; Kwon, SG; Lee, JH; Moon, JY; Oh, SB; Roh, DH; Yoon, SY | 1 |
| Bringmann, A; Pannicke, T; Reichenbach, A; Vogler, S; Wiedemann, P; Winters, H | 1 |
| Álvarez, M; Andino Norat, MC; Gorantla, S; López, OV; Meléndez, LM; Segarra, AC; Skolasky, RL | 1 |
| Kadnikov, IA; Seredenin, SB; Voronin, MV; Voronkov, DN | 1 |
| Kadnikov, IA; Seredenin, SB; Verbovaya, ER; Voronin, MV; Voronkov, DN | 1 |
21 other study(ies) available for pre 084 and bd 1047
| Article | Year |
|---|---|
Cocaine modulates cytokine and enhances tumor growth through sigma receptors.
Topics: Adenocarcinoma, Bronchiolo-Alveolar; Anesthetics, Local; Animals; Antibodies; Cell Line, Tumor; Cell Size; Cocaine; Cytokines; Drug Interactions; Ethylenediamines; Interferon-gamma; Interleukin-10; Mice; Mice, Inbred BALB C; Morpholines; Neoplasms; Receptors, sigma; Th2 Cells; Transplants | 2004 |
Effects of neurosteroids on ischemia-reperfusion injury in the rat retina: role of sigma1 recognition sites.
Topics: Adenosine Triphosphate; Animals; Binding Sites; Dehydroepiandrosterone Sulfate; Estradiol; Ethylenediamines; Glucose; Injections, Intraperitoneal; Lactates; Male; Morpholines; Rats; Rats, Sprague-Dawley; Receptors, sigma; Reperfusion Injury; Retina; Retinal Degeneration | 2004 |
Phenytoin differentially modulates the affinity of agonist and antagonist ligands for sigma 1 receptors of guinea pig brain.
Topics: Allosteric Regulation; Animals; Anisoles; Anticonvulsants; Binding, Competitive; Brain; Dextromethorphan; Drug Interactions; Ethylenediamines; Guinea Pigs; Haloperidol; Ligands; Male; Morpholines; Neurons; Phenazocine; Phenytoin; Piperazines; Piperidines; Progesterone; Propylamines; Receptors, sigma; Synaptic Transmission | 2005 |
Sigma receptor ligands protect human retinal cells against oxidative stress.
Topics: Anisoles; Cell Survival; Cells, Cultured; DNA Damage; Dose-Response Relationship, Drug; Drug Interactions; Epithelial Cells; Ethylenediamines; Humans; Hydrogen Peroxide; Morpholines; Oxidative Stress; Propylamines; Receptors, sigma; Retina | 2006 |
Sigma-1 receptor activation prevents intracellular calcium dysregulation in cortical neurons during in vitro ischemia.
Topics: Analgesics, Opioid; Animals; Brain Ischemia; Calcium; Calcium Signaling; Cerebral Cortex; Cyclopentanes; Cytophotometry; Enzyme Inhibitors; Ethylenediamines; Female; Guanidines; Morpholines; Neurons; Pentazocine; Phencyclidine; Pregnancy; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, sigma; Sigma-1 Receptor; Sodium Azide; Sodium Channel Agonists; Tetrodotoxin | 2006 |
Involvement of the sigma1 receptor in inhibiting activity of fluvoxamine on marble-burying behavior: comparison with paroxetine.
Topics: Animals; Behavior, Animal; Brain; Butyrates; Disease Models, Animal; Dose-Response Relationship, Drug; Ethylenediamines; Fluvoxamine; Male; Mice; Mice, Inbred ICR; Morpholines; Obsessive-Compulsive Disorder; Paroxetine; Phenazocine; Piperazines; Psychotropic Drugs; Receptors, sigma; Selective Serotonin Reuptake Inhibitors; Sigma-1 Receptor; Tropanes | 2007 |
Protective effects of the sigma agonist Pre-084 in the rat retina.
Topics: Amyloid beta-Peptides; Animals; bcl-2-Associated X Protein; Ethylenediamines; Injections; Male; MAP Kinase Kinase 4; Models, Animal; Morpholines; Neuroprotective Agents; Phosphorylation; Rats; Rats, Sprague-Dawley; Receptors, sigma; Receptors, TNF-Related Apoptosis-Inducing Ligand; Retina; Signal Transduction; TNF-Related Apoptosis-Inducing Ligand; Vitreous Body | 2007 |
Activation of the spinal sigma-1 receptor enhances NMDA-induced pain via PKC- and PKA-dependent phosphorylation of the NR1 subunit in mice.
Topics: Animals; Behavior, Animal; Blotting, Western; Cyclic AMP-Dependent Protein Kinases; Cyclopentanes; Disease Models, Animal; Dose-Response Relationship, Drug; Ethylenediamines; Immunohistochemistry; Injections, Spinal; Male; Mice; Mice, Inbred ICR; Morpholines; N-Methylaspartate; Pain; Pain Measurement; Phosphorylation; Posterior Horn Cells; Protein Kinase C; Receptors, N-Methyl-D-Aspartate; Receptors, sigma; Serine; Sigma-1 Receptor; Signal Processing, Computer-Assisted; Signal Transduction; Spinal Cord; Time Factors | 2008 |
Intrathecal administration of sigma-1 receptor agonists facilitates nociception: involvement of a protein kinase C-dependent pathway.
Topics: Animals; Antitussive Agents; Calcium Signaling; Cyclopentanes; Disease Models, Animal; Enzyme Inhibitors; Ethylenediamines; Inflammation Mediators; Injections, Spinal; Male; Mice; Mice, Inbred ICR; Morpholines; Nociceptors; Pain; Pain Measurement; Pain Threshold; Posterior Horn Cells; Protein Kinase C; Proto-Oncogene Proteins c-fos; Receptors, sigma; Sigma-1 Receptor; Signal Transduction; Spinal Cord | 2008 |
Sigma-1 receptors are essential for capsaicin-induced mechanical hypersensitivity: studies with selective sigma-1 ligands and sigma-1 knockout mice.
Topics: Animals; Anisoles; Capsaicin; DNA; Ethylenediamines; Female; Hyperalgesia; Mice; Mice, Knockout; Morpholines; Nociceptors; Pain Measurement; Pain Threshold; Physical Stimulation; Piperazines; Polymerase Chain Reaction; Propylamines; Reaction Time; Receptors, sigma; Sensory Receptor Cells; Sensory System Agents; Sigma-1 Receptor; Spinal Cord | 2009 |
Sigma receptor agonists: receptor binding and effects on mesolimbic dopamine neurotransmission assessed by microdialysis.
Topics: Animals; Benzoxazoles; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Drug Interactions; Ethylamines; Ethylenediamines; Guanidines; Male; Microdialysis; Morpholines; Nucleus Accumbens; Piperazines; Pyrrolidines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, sigma; Synaptic Transmission | 2011 |
Influence of sigma-1 receptor modulators on ethanol-induced conditioned place preference in the extinction-reinstatement model.
Topics: Animals; Conditioning, Psychological; Dose-Response Relationship, Drug; Ethanol; Ethylenediamines; Extinction, Psychological; Male; Mice; Morpholines; Receptors, sigma; Sigma-1 Receptor | 2012 |
Sigma-1 receptor-mediated increase in spinal p38 MAPK phosphorylation leads to the induction of mechanical allodynia in mice and neuropathic rats.
Topics: Analysis of Variance; Animals; Disease Models, Animal; Enzyme Inhibitors; Ethylenediamines; Hyperalgesia; Imidazoles; Male; Mice; Mice, Inbred ICR; Morpholines; p38 Mitogen-Activated Protein Kinases; Pain Measurement; Pain Threshold; Phosphorylation; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, sigma; Sciatica; Sigma-1 Receptor; Spinal Cord | 2013 |
Spinal sigma-1 receptors activate NADPH oxidase 2 leading to the induction of pain hypersensitivity in mice and mechanical allodynia in neuropathic rats.
Topics: Animals; Ethylenediamines; Hot Temperature; Hyperalgesia; Male; Membrane Glycoproteins; Mice; Mice, Inbred ICR; Morpholines; NADPH Oxidase 2; NADPH Oxidases; Neuralgia; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Receptors, sigma; Sigma-1 Receptor; Spinal Cord; Touch | 2013 |
NMDA receptors are upregulated and trafficked to the plasma membrane after sigma-1 receptor activation in the rat hippocampus.
Topics: Animals; Cell Membrane; Disks Large Homolog 4 Protein; Ethylenediamines; Hippocampus; Intracellular Signaling Peptides and Proteins; Male; Membrane Proteins; Mice; Mice, Knockout; Morpholines; Pentazocine; Phenazocine; Piperazines; Protein Transport; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Receptors, sigma; Sigma-1 Receptor; Subcellular Fractions; Time Factors; Up-Regulation | 2014 |
Role of peripheral sigma-1 receptors in ischaemic pain: Potential interactions with ASIC and P2X receptors.
Topics: Acid Sensing Ion Channels; Adenosine Triphosphate; Animals; Ethylenediamines; Hindlimb; Hyperalgesia; Ischemia; Male; Morpholines; Pain; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2X; Receptors, sigma; Sigma-1 Receptor | 2016 |
Sigma-1 receptor activation inhibits osmotic swelling of rat retinal glial (Müller) cells by transactivation of glutamatergic and purinergic receptors.
Topics: Animals; Cell Size; Ependymoglial Cells; Estradiol; Ethylenediamines; Excitatory Amino Acid Antagonists; Female; In Vitro Techniques; Male; Morpholines; Osmosis; Purinergic P2 Receptor Antagonists; Rats, Long-Evans; Receptors, Glutamate; Receptors, Purinergic P2Y1; Receptors, sigma; Transcriptional Activation | 2016 |
Spinal D-Serine Increases PKC-Dependent GluN1 Phosphorylation Contributing to the Sigma-1 Receptor-Induced Development of Mechanical Allodynia in a Mouse Model of Neuropathic Pain.
Topics: Animals; D-Amino-Acid Oxidase; Disease Models, Animal; Enzyme Inhibitors; Ethylenediamines; Excitatory Amino Acid Agonists; Gene Expression Regulation; Hyperalgesia; Male; Mice; Mice, Inbred ICR; Morpholines; N-Methylaspartate; Nerve Tissue Proteins; Neuralgia; Phosphorylation; Physical Stimulation; Protein Kinase C; Receptors, N-Methyl-D-Aspartate; Receptors, sigma; Serine; Sigma-1 Receptor; Spinal Cord | 2017 |
Sigma-1 Receptor Antagonist (BD1047) Decreases Cathepsin B Secretion in HIV-Infected Macrophages Exposed to Cocaine.
Topics: Animals; Apoptosis; Brain; Caspase 3; Cathepsin B; Cell Line; Cocaine; Ethylenediamines; Female; HIV Core Protein p24; HIV Infections; Humans; Immunohistochemistry; Macrophages; Mice; Mice, Inbred ICR; Morpholines; Receptors, sigma; Sigma-1 Receptor; Young Adult | 2019 |
Chaperone Sigma1R mediates the neuroprotective action of afobazole in the 6-OHDA model of Parkinson's disease.
Topics: Animals; Benzimidazoles; Corpus Striatum; Disease Models, Animal; Dopamine; Ethylenediamines; Male; Mice; Mice, Inbred ICR; Morpholines; Neurons; Neuroprotection; Neuroprotective Agents; Oxidopamine; Parkinson Disease; Receptors, sigma; Rotarod Performance Test; Sigma-1 Receptor; Substantia Nigra | 2019 |
Deferred Administration of Afobazole Induces Sigma1R-Dependent Restoration of Striatal Dopamine Content in a Mouse Model of Parkinson's Disease.
Topics: Animals; Benzimidazoles; Corpus Striatum; Dopamine; Ethylenediamines; Male; Mice; Mice, Inbred ICR; Morpholines; Movement; Parkinson Disease; Receptors, sigma; Sigma-1 Receptor | 2020 |