Page last updated: 2024-09-03

pre 084 and alpha-(4-fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazine butanol

pre 084 has been researched along with alpha-(4-fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazine butanol in 2 studies

Compound Research Comparison

Studies
(pre 084)
Trials
(pre 084)
Recent Studies (post-2010)
(pre 084)
Studies
(alpha-(4-fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazine butanol)
Trials
(alpha-(4-fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazine butanol)
Recent Studies (post-2010) (alpha-(4-fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazine butanol)
1160739012

Protein Interaction Comparison

ProteinTaxonomypre 084 (IC50)alpha-(4-fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazine butanol (IC50)
Cytochrome P450 3A4Homo sapiens (human)0.83
Tryptophan 5-hydroxylase 1Rattus norvegicus (Norway rat)6.43
5-hydroxytryptamine receptor 2ARattus norvegicus (Norway rat)0.83
Alpha-1B adrenergic receptorRattus norvegicus (Norway rat)0.8267
5-hydroxytryptamine receptor 1ARattus norvegicus (Norway rat)0.91
Alpha-1D adrenergic receptorRattus norvegicus (Norway rat)0.8267
5-hydroxytryptamine receptor 1BRattus norvegicus (Norway rat)1.5
5-hydroxytryptamine receptor 1DRattus norvegicus (Norway rat)1.5
5-hydroxytryptamine receptor 1FRattus norvegicus (Norway rat)1.5
Alpha-1A adrenergic receptorRattus norvegicus (Norway rat)0.8267
D(2) dopamine receptorMus musculus (house mouse)2.431
D(2) dopamine receptorRattus norvegicus (Norway rat)6.9225
Sigma non-opioid intracellular receptor 1Homo sapiens (human)0.06
Sigma non-opioid intracellular receptor 1Rattus norvegicus (Norway rat)0.073

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Maurice, T; Nabeshima, T; Parish, DW; Privat, A; Su, TP1
Maurice, T; Privat, A; Roman, FJ; Su, TP1

Other Studies

2 other study(ies) available for pre 084 and alpha-(4-fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazine butanol

ArticleYear
PRE-084, a sigma selective PCP derivative, attenuates MK-801-induced impairment of learning in mice.
    Pharmacology, biochemistry, and behavior, 1994, Volume: 49, Issue:4

    Topics: Amnesia; Animals; Anti-Anxiety Agents; Avoidance Learning; Cholinergic Agents; Dizocilpine Maleate; Dose-Response Relationship, Drug; Haloperidol; Learning; Male; Maze Learning; Memory; Memory, Short-Term; Mice; Morpholines; Phencyclidine; Pyrimidines; Rats; Rats, Wistar; Receptors, sigma

1994
Beneficial effects of sigma agonists on the age-related learning impairment in the senescence-accelerated mouse (SAM).
    Brain research, 1996, Sep-16, Volume: 733, Issue:2

    Topics: Aging; Animals; Anti-Anxiety Agents; Antipsychotic Agents; Avoidance Learning; Cinnamates; Cyclopropanes; Learning; Maze Learning; Memory; Mice; Mice, Neurologic Mutants; Morpholines; Motor Activity; Phenazocine; Pyrimidines; Receptors, sigma

1996