Page last updated: 2024-08-23

pravastatin and wortmannin

pravastatin has been researched along with wortmannin in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bilter, GK; Dias, J; Huang, Z; Keon, BH; Lamerdin, J; MacDonald, ML; Michnick, SW; Minami, T; Owens, S; Shang, Z; Westwick, JK; Yu, H1
Asano, Y; Asanuma, H; Fujita, M; Hirata, A; Hori, M; Kim, J; Kitakaze, M; Kitamura, S; Minamino, T; Mori, H; Node, K; Ogai, A; Okuda, H; Sanada, S; Shinozaki, Y; Takashima, S; Tomoike, H1
Imawari, M; Kim, M; Kusama, K; Nozu, F1
Akishita, M; Eto, M; Iijima, K; Kozaki, K; Nakano, T; Ouchi, Y; Son, BK1
Ichihara, K; Itagaki, M; Kaneta, S; Kano, S; Satoh, K; Takaguri, A1

Other Studies

5 other study(ies) available for pravastatin and wortmannin

ArticleYear
Identifying off-target effects and hidden phenotypes of drugs in human cells.
    Nature chemical biology, 2006, Volume: 2, Issue:6

    Topics: Bacterial Proteins; Cell Line; Cell Proliferation; Cluster Analysis; Drug Design; Drug Evaluation, Preclinical; Genetics; Humans; Luminescent Proteins; Molecular Structure; Phenotype; Recombinant Fusion Proteins; Signal Transduction; Structure-Activity Relationship

2006
Optimal windows of statin use for immediate infarct limitation: 5'-nucleotidase as another downstream molecule of phosphatidylinositol 3-kinase.
    Circulation, 2004, Oct-12, Volume: 110, Issue:15

    Topics: 5'-Nucleotidase; Adenosine Triphosphate; Androstadienes; Animals; Cardiotonic Agents; Chromones; Coronary Disease; Dogs; Dose-Response Relationship, Drug; Enzyme Activation; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Morpholines; Myocardial Infarction; Myocardial Reperfusion Injury; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Pravastatin; Pyridines; Quinolines; Signal Transduction; Theophylline; Wortmannin

2004
Cholecystokinin stimulates the recruitment of the Src-RhoA-phosphoinositide 3-kinase pathway by Vav-2 downstream of G(alpha13) in pancreatic acini.
    Biochemical and biophysical research communications, 2006, Jan-06, Volume: 339, Issue:1

    Topics: Amylases; Androstadienes; Animals; Benzoquinones; Cholecystokinin; GTP-Binding Protein alpha Subunits, G12-G13; In Vitro Techniques; Lactams, Macrocyclic; Male; Pancreas, Exocrine; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Pravastatin; Proto-Oncogene Proteins c-vav; Quinones; Rats; Rats, Sprague-Dawley; rhoA GTP-Binding Protein; Rifabutin; Signal Transduction; src-Family Kinases; Wortmannin

2006
Gas6/Axl-PI3K/Akt pathway plays a central role in the effect of statins on inorganic phosphate-induced calcification of vascular smooth muscle cells.
    European journal of pharmacology, 2007, Feb-05, Volume: 556, Issue:1-3

    Topics: Androstadienes; Apoptosis; Axl Receptor Tyrosine Kinase; bcl-Associated Death Protein; Calcinosis; Caspase 3; Cells, Cultured; Enzyme Activation; Fatty Acids, Monounsaturated; Fluvastatin; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indoles; Intercellular Signaling Peptides and Proteins; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Oncogene Proteins; Phosphates; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Pravastatin; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Receptor Protein-Tyrosine Kinases; Signal Transduction; Wortmannin

2007
Possible mechanisms underlying statin-induced skeletal muscle toxicity in L6 fibroblasts and in rats.
    Journal of pharmacological sciences, 2009, Volume: 109, Issue:1

    Topics: Amides; Androstadienes; Animals; Caspase 3; Cell Culture Techniques; Cell Survival; Creatine Kinase; Dose-Response Relationship, Drug; Fatty Acids, Monounsaturated; Fibroblasts; Fluvastatin; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indoles; Infusions, Intravenous; L Cells; Mice; Muscle, Skeletal; Pravastatin; Pyridines; Rats; rho-Associated Kinases; rhoA GTP-Binding Protein; Simvastatin; Subcellular Fractions; Time Factors; Wortmannin

2009