pravastatin has been researched along with taurocholic acid in 26 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (19.23) | 18.2507 |
| 2000's | 13 (50.00) | 29.6817 |
| 2010's | 8 (30.77) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Abe, T; Nakagomi, R; Nakai, D; Sugiyama, Y; Tokui, T; Yawo, H | 1 |
| Hsiang, B; Kirchgessner, TG; Sasseville, V; Wang, Z; Wu, Y; Yang, WP; Zhu, Y | 1 |
| Imai, K; Nezu, J; Nozawa, T; Tamai, I; Tsuji, A | 1 |
| Hori, S; Kikkawa, T; Mori, S; Ohtsuki, S; Otagiri, M; Takanaga, H; Terasaki, T | 1 |
| Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Benet, LZ; Brouwer, KL; Chu, X; Dahlin, A; Evers, R; Fischer, V; Giacomini, KM; Hillgren, KM; Hoffmaster, KA; Huang, SM; Ishikawa, T; Keppler, D; Kim, RB; Lee, CA; Niemi, M; Polli, JW; Sugiyama, Y; Swaan, PW; Tweedie, DJ; Ware, JA; Wright, SH; Yee, SW; Zamek-Gliszczynski, MJ; Zhang, L | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Fent, K; Popovic, M; Smital, T; Zaja, R | 1 |
| Horie, T; Nishikawa, K; Sano, N; Takikawa, H; Yamanaka, M | 1 |
| Blumrich, M; Hummelsiep, S; Ziegler, K | 1 |
| Hanano, M; Komai, T; Sugiyama, Y; Suzuki, H; Tokui, T; Yamazaki, M | 1 |
| Berr, F; Bitterle, T; Jaeger, H; Mössner, J; Wilcox, HG | 1 |
| Abe, T; Furuta, Y; Ikeda, T; Nakagomi, R; Nakai, D; Nishimura, K; Tokui, T | 1 |
| Ohashi, M; Sano, N; Takikawa, H | 1 |
| Abe, T; Endou, H; Kikuchi, R; Kusuhara, H; Sugiyama, Y | 1 |
| Sano, N; Takayanagi, M; Takikawa, H | 1 |
| Hayashi, H; Hirano, M; Kusuhara, H; Maeda, K; Sugiyama, Y | 1 |
| Brun, ME; Funk, C; Noé, J; Portmann, R | 1 |
| Fromm, MF; Klein, K; König, J; Seithel, A; Zanger, UM | 1 |
| Brouwer, KL; Brouwer, KR; Pollack, GM; Wolf, KK | 1 |
| Maeda, M; Ohashi, R; Oka, M; Takemura, M; Tamai, I; Tanaka, K; Yabuuchi, H | 1 |
| Endo, C; Kitamura, S; Kusuhara, H; Miyajima, M; Ose, A; Sugiyama, Y; Tohyama, K | 1 |
| Bi, YA; Gong, LK; Hiramatsu, M; Kotani, N; Kusuhara, H; Maeda, K; Sugiyama, Y; Takezawa, T; Watanabe, T | 1 |
| Abraham, P; Cheng, Y; Freeden, C; Gan, J; Humphreys, WG; Lai, Y; Shen, H; Wescott, D; Zhang, Y | 1 |
| Fromm, MF; Glaeser, H; Gruetz, M; König, J; Sticht, H | 1 |
1 review(s) available for pravastatin and taurocholic acid
| Article | Year |
|---|---|
Membrane transporters in drug development.
Topics: Animals; Computer Simulation; Decision Trees; Drug Approval; Drug Discovery; Drug Evaluation, Preclinical; Drug Interactions; Humans; Membrane Transport Proteins; Mice; Mice, Knockout; Prescription Drugs | 2010 |
25 other study(ies) available for pravastatin and taurocholic acid
| Article | Year |
|---|---|
Pravastatin, an HMG-CoA reductase inhibitor, is transported by rat organic anion transporting polypeptide, oatp2.
Topics: Animals; Anion Transport Proteins; Biological Transport; Carbon Radioisotopes; Carrier Proteins; Cholates; Enzyme Inhibitors; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Oocytes; Pravastatin; Rats; Simvastatin; Xenopus laevis | 1999 |
A novel human hepatic organic anion transporting polypeptide (OATP2). Identification of a liver-specific human organic anion transporting polypeptide and identification of rat and human hydroxymethylglutaryl-CoA reductase inhibitor transporters.
Topics: Amino Acid Sequence; Animals; Anion Transport Proteins; Base Sequence; Biological Transport; Carrier Proteins; Dehydroepiandrosterone Sulfate; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Liver; Molecular Sequence Data; Pravastatin; Rats; Taurocholic Acid | 1999 |
Functional characterization of pH-sensitive organic anion transporting polypeptide OATP-B in human.
Topics: Biological Transport; Cells, Cultured; Estrone; Humans; Hydrogen-Ion Concentration; Organic Anion Transporters | 2004 |
Mouse reduced in osteosclerosis transporter functions as an organic anion transporter 3 and is localized at abluminal membrane of blood-brain barrier.
Topics: Animals; Biological Transport; Blood-Brain Barrier; Capillaries; Disease Models, Animal; Estrone; Male; Membrane Transport Proteins; Mice; Mice, Inbred C57BL; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Osteosclerosis; Penicillin G; RNA, Messenger | 2004 |
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship | 2008 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Molecular characterization of zebrafish Oatp1d1 (Slco1d1), a novel organic anion-transporting polypeptide.
Topics: Animals; Evolution, Molecular; Glycosylation; Gonadal Steroid Hormones; HEK293 Cells; Humans; Ion Transport; Organic Anion Transporters; Protein Multimerization; Zebrafish; Zebrafish Proteins | 2013 |
Mechanisms of biliary excretion of lithocholate-3-sulfate in Eisai hyperbilirubinemic rats (EHBR).
Topics: Animals; Bile; Colchicine; Hyperbilirubinemia; Indocyanine Green; Lithocholic Acid; Male; Pravastatin; Rats; Rats, Mutant Strains; Rats, Sprague-Dawley; Sulfobromophthalein; Taurocholic Acid | 1995 |
The transporter for the HMG-CoA reductase inhibitor pravastatin is not present in Hep G2 cells. Evidence for the nonidentity of the carrier for pravastatin and certain transport systems for BSP.
Topics: Animals; Carrier Proteins; Cells, Cultured; Chlorides; Cholic Acid; Cholic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Pravastatin; Rats; Serum Albumin, Bovine; Sulfobromophthalein; Taurocholic Acid; Tumor Cells, Cultured | 1994 |
Na(+)-independent multispecific anion transporter mediates active transport of pravastatin into rat liver.
Topics: Animals; Anion Transport Proteins; Bile Acids and Salts; Biological Transport, Active; Carrier Proteins; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Liver; Osmolar Concentration; Pravastatin; Rats; Sodium; Sulfhydryl Reagents; Taurocholic Acid; Temperature; Time Factors | 1993 |
Intracellular supply of phospholipids for biliary secretion: evidence for a nonvesicular transport component.
Topics: Animals; Apolipoprotein A-I; Bile; Bilirubin; Biological Transport, Active; Brefeldin A; Carrier Proteins; Cycloheximide; Cytosol; Endoplasmic Reticulum; Golgi Apparatus; In Vitro Techniques; Intracellular Fluid; Liver; Male; Perfusion; Phospholipids; Pravastatin; Rats; Rats, Sprague-Dawley; Taurine; Taurocholic Acid | 2000 |
Human liver-specific organic anion transporter, LST-1, mediates uptake of pravastatin by human hepatocytes.
Topics: Animals; Anion Transport Proteins; Biological Transport; Carbon Radioisotopes; Carcinoma, Hepatocellular; Carrier Proteins; Cells, Cultured; Dose-Response Relationship, Drug; Estradiol; Female; Glucuronides; Hepatocytes; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunohistochemistry; Oocytes; Pravastatin; Taurocholic Acid; Tritium; Xenopus laevis | 2001 |
Effects of phalloidin on the biliary excretion of cholephilic compounds in rats.
Topics: Animals; Anticholesteremic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Bile; Biological Transport; Cholagogues and Choleretics; Glutathione; Leukotriene C4; Male; Membrane Transport Proteins; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Phalloidine; Pravastatin; Rats; Rats, Sprague-Dawley; Taurocholic Acid; Vinblastine | 2002 |
Involvement of multiple transporters in the efflux of 3-hydroxy-3-methylglutaryl-CoA reductase inhibitors across the blood-brain barrier.
Topics: Animals; Blood-Brain Barrier; Brain; Carrier Proteins; Digoxin; DNA, Complementary; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Kinetics; Male; Microinjections; Organic Anion Transporters, Sodium-Independent; p-Aminohippuric Acid; Pravastatin; Quinolines; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Taurocholic Acid | 2004 |
Biliary excretion of olmesartan, an anigotensin II receptor antagonist, in the rat.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; ATP-Binding Cassette Transporters; Cephalosporins; Common Bile Duct; Imidazoles; Male; Olmesartan Medoxomil; Phenothiazines; Pravastatin; Rats; Rats, Mutant Strains; Rats, Sprague-Dawley; Sulfobromophthalein; Taurochenodeoxycholic Acid; Taurocholic Acid; Tetrazoles; Vinblastine | 2005 |
Bile salt export pump (BSEP/ABCB11) can transport a nonbile acid substrate, pravastatin.
Topics: Adenosine Triphosphate; Adenoviridae; Algorithms; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport, Active; Chemical Phenomena; Chemistry, Physical; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Kinetics; Pravastatin; Rats; Taurocholic Acid; Transport Vesicles | 2005 |
Substrate-dependent drug-drug interactions between gemfibrozil, fluvastatin and other organic anion-transporting peptide (OATP) substrates on OATP1B1, OATP2B1, and OATP1B3.
Topics: Animals; Anticholesteremic Agents; Biological Transport; Cell Line; CHO Cells; Chromans; Cricetinae; Cricetulus; Drug Interactions; Estrone; Fatty Acids, Monounsaturated; Fluvastatin; Gemfibrozil; Hepatocytes; Humans; Hypoglycemic Agents; Hypolipidemic Agents; Indoles; Kinetics; Liver-Specific Organic Anion Transporter 1; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Pravastatin; Protein Binding; Recombinant Proteins; Simvastatin; Solute Carrier Organic Anion Transporter Family Member 1B3; Taurocholic Acid; Thiazolidinediones; Troglitazone | 2007 |
Non-synonymous polymorphisms in the human SLCO1B1 gene: an in vitro analysis of SNP c.1929A>C.
Topics: Aged; Biological Transport; Cell Line; Female; Gene Frequency; Genotype; Humans; Immunoblotting; Liver; Liver-Specific Organic Anion Transporter 1; Male; Middle Aged; Organic Anion Transporters; Polymorphism, Single Nucleotide; Pravastatin; Sulfobromophthalein; Taurocholic Acid; Transfection | 2008 |
Effect of albumin on the biliary clearance of compounds in sandwich-cultured rat hepatocytes.
Topics: Animals; Biliary Tract; Chromatography, Liquid; Digoxin; Hepatocytes; Liver; Male; Microscopy, Fluorescence; Pravastatin; Rats; Rats, Wistar; Serum Albumin, Bovine; Tandem Mass Spectrometry; Taurocholic Acid | 2008 |
Cloning of the dog bile salt export pump (BSEP; ABCB11) and functional comparison with the human and rat proteins.
Topics: Amino Acid Sequence; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Chromans; Cloning, Molecular; Dogs; Humans; Molecular Sequence Data; Organ Specificity; Pravastatin; Rats; Species Specificity; Spodoptera; Taurocholic Acid; Thiazolidinediones; Troglitazone | 2008 |
Functional characterization of mouse organic anion transporting peptide 1a4 in the uptake and efflux of drugs across the blood-brain barrier.
Topics: Acridines; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Blood-Brain Barrier; Brain; Capillaries; Cell Line; Cell Membrane; Cerebral Cortex; Choroid Plexus; Digoxin; Enkephalin, D-Penicillamine (2,5)-; Fluorobenzenes; Gene Expression; Humans; Ion Pumps; Kinetics; Liver; Mice; Mice, Inbred C57BL; Mice, Knockout; Ochratoxins; Organic Anion Transporters; Organic Cation Transport Proteins; Pharmaceutical Preparations; Pravastatin; Pyrimidines; Quinolines; Recombinant Proteins; Rosuvastatin Calcium; Sulfonamides; Taurocholic Acid; Tetrahydroisoquinolines; Transfection | 2010 |
Culture period-dependent changes in the uptake of transporter substrates in sandwich-cultured rat and human hepatocytes.
Topics: Animals; Bile; Biological Transport; Cell Culture Techniques; Cells, Cultured; Digoxin; Fluorobenzenes; Hepatocytes; Humans; Inactivation, Metabolic; Liver; Male; Membrane Transport Proteins; Pravastatin; Pyrimidines; Rats; Rats, Sprague-Dawley; Rosuvastatin Calcium; Sulfonamides; Taurocholic Acid | 2011 |
Biliary excretion of pravastatin and taurocholate in rats with bile salt export pump (Bsep) impairment.
Topics: Animals; Anticholesteremic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile; Bile Acids and Salts; Cholagogues and Choleretics; Liver; Male; Pravastatin; Rats, Sprague-Dawley; Rats, Transgenic; Taurocholic Acid | 2016 |
Analysis of amino acid residues in the predicted transmembrane pore influencing transport kinetics of the hepatic drug transporter organic anion transporting polypeptide 1B1 (OATP1B1).
Topics: Amino Acid Sequence; Biological Transport; Estradiol; Gene Expression; HEK293 Cells; Humans; Kinetics; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Pravastatin; Protein Interaction Domains and Motifs; Protein Structure, Secondary; Recombinant Proteins; Sequence Alignment; Structure-Activity Relationship; Sulfobromophthalein; Taurocholic Acid; Transgenes | 2016 |