Page last updated: 2024-08-23

pravastatin and squalene

pravastatin has been researched along with squalene in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (44.44)18.2507
2000's2 (22.22)29.6817
2010's3 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Miettinen, TA; Vanhanen, HT1
Corsini, A; Fumagalli, R; Gabbiani, G; Mazzotti, M; Paoletti, R; Raiteri, M; Soma, MR1
Chan, P; Lee, CB; Lee, YS; Tomlinson, B1
Durham, SK; Flint, OP; Gregg, RE; Masters, BA1
Ikeda, U; Inaba, H; Ohki, R; Shimada, K; Shimpo, M; Takahashi, M; Yamamoto, K1
Alvarez, AM; García-Román, N; Lorenzo, MJ; Montes, A; Toro, MJ1
Blasko, J; Hapala, I; Nováková, Z; Smigán, P1
Alleva, K; Angeletti, M; Ardila, F; Ayub, ND; Cuccioloni, M; Lisi, C; Mozzicafreddo, M; Pagano, ME; Soto, G; Stritzler, M1
Fang, Y; Jaiseng, W; Kuno, T; Ma, Y; Takami, T; Zhou, X1

Trials

2 trial(s) available for pravastatin and squalene

ArticleYear
Cholesterol absorption and synthesis during pravastatin, gemfibrozil and their combination.
    Atherosclerosis, 1995, Volume: 115, Issue:2

    Topics: Absorption; Apolipoproteins; Cholestanol; Cholesterol; Double-Blind Method; Drug Therapy, Combination; Female; Gemfibrozil; Humans; Hyperlipidemias; Lipoproteins; Male; Middle Aged; Pravastatin; Squalene; Sterols; Triglycerides

1995
Effectiveness and safety of low-dose pravastatin and squalene, alone and in combination, in elderly patients with hypercholesterolemia.
    Journal of clinical pharmacology, 1996, Volume: 36, Issue:5

    Topics: Aged; Anticholesteremic Agents; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hypercholesterolemia; Male; Placebos; Pravastatin; Squalene; Triglycerides

1996

Other Studies

7 other study(ies) available for pravastatin and squalene

ArticleYear
Relationship between mevalonate pathway and arterial myocyte proliferation: in vitro studies with inhibitors of HMG-CoA reductase.
    Atherosclerosis, 1993, Volume: 101, Issue:1

    Topics: Acyclic Monoterpenes; Animals; Aorta; Cell Division; Cells, Cultured; Cholesterol; Diterpenes; Dose-Response Relationship, Drug; Farnesol; Fatty Acids, Monounsaturated; Femoral Artery; Fluvastatin; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indoles; Lovastatin; Male; Mevalonic Acid; Muscle, Smooth, Vascular; Pravastatin; Rats; Rats, Sprague-Dawley; Simvastatin; Squalene; Terpenes

1993
Inhibition of cholesterol synthesis by squalene synthase inhibitors does not induce myotoxicity in vitro.
    Toxicology and applied pharmacology, 1997, Volume: 145, Issue:1

    Topics: Analysis of Variance; Animals; Animals, Newborn; Anticholesteremic Agents; Butylamines; Cells, Cultured; Cholesterol; Diterpenes; Enzyme Inhibitors; Farnesol; Farnesyl-Diphosphate Farnesyltransferase; Female; Hydroxymethylglutaryl-CoA Reductase Inhibitors; L-Lactate Dehydrogenase; Lovastatin; Mevalonic Acid; Muscle, Skeletal; Pravastatin; Pregnancy; Prodrugs; Protein Biosynthesis; Rats; Rats, Sprague-Dawley; Squalene; Sulfonic Acids

1997
Fluvastatin inhibits matrix metalloproteinase-1 expression in human vascular endothelial cells.
    Hypertension (Dallas, Tex. : 1979), 2000, Volume: 36, Issue:3

    Topics: Analysis of Variance; Anticholesteremic Agents; Dose-Response Relationship, Drug; Endothelium, Vascular; Fatty Acids, Monounsaturated; Fluvastatin; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indoles; Lovastatin; Matrix Metalloproteinase 1; Mevalonic Acid; Polyisoprenyl Phosphates; Pravastatin; Sesquiterpenes; Squalene; Time Factors; Tissue Inhibitor of Metalloproteinase-1

2000
Lovastatin induces apoptosis of spontaneously immortalized rat brain neuroblasts: involvement of nonsterol isoprenoid biosynthesis inhibition.
    Molecular and cellular neurosciences, 2001, Volume: 17, Issue:2

    Topics: Animals; Anticholesteremic Agents; Apoptosis; bcl-2-Associated X Protein; bcl-Associated Death Protein; bcl-X Protein; Carrier Proteins; Cell Division; Cell Line, Transformed; Cholesterol; Lovastatin; Mevalonic Acid; Neurons; Polyisoprenyl Phosphates; Pravastatin; Protein Prenylation; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Rats; Sesquiterpenes; Squalene; Stem Cells

2001
Effects of 3-hydroxy-3-methylglutaryl-coenzyme a reductase inhibitor pravastatin on membrane lipids and membrane associated functions of Methanothermobacter thermautotrophicus.
    Folia microbiologica, 2010, Volume: 55, Issue:4

    Topics: Cell Membrane; Electrophoresis, Polyacrylamide Gel; Energy Metabolism; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Membrane Lipids; Methanobacteriaceae; Pravastatin; Proton-Translocating ATPases; Sodium-Hydrogen Exchangers; Squalene

2010
Acetoacetyl-CoA thiolase regulates the mevalonate pathway during abiotic stress adaptation.
    Journal of experimental botany, 2011, Volume: 62, Issue:15

    Topics: Acetyl-CoA C-Acetyltransferase; Medicago sativa; Mevalonic Acid; Plant Leaves; Plant Proteins; Plant Roots; Plants, Genetically Modified; Pravastatin; Real-Time Polymerase Chain Reaction; Signal Transduction; Squalene

2011
A genetic and pharmacological analysis of isoprenoid pathway by LC-MS/MS in fission yeast.
    PloS one, 2012, Volume: 7, Issue:11

    Topics: Antifungal Agents; Chromatography, Liquid; Ergosterol; HMGB1 Protein; Hydroxymethylglutaryl CoA Reductases; Lanosterol; Miconazole; Mutation; Naphthalenes; Polyisoprenyl Phosphates; Pravastatin; Schizosaccharomyces; Sesquiterpenes; Squalene; Sterols; Tandem Mass Spectrometry; Terbinafine

2012