Page last updated: 2024-08-23

pravastatin and simvastatin acid

pravastatin has been researched along with simvastatin acid in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (42.86)18.2507
2000's3 (42.86)29.6817
2010's1 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Campbell, SD; Chen, C; Lin, J; Mills, JB; Mireles, RJ; Smolarek, TA; Xu, JJ1
Ahmad, S; Barrish, JC; Bird, E; Bisaha, S; Blanar, MA; Chang, M; Chen, BC; Chen, X; Cuff, CA; Darienzo, CJ; Giancarli, M; Harrity, T; Huang, C; Janovitz, E; Kennedy, LJ; Li, T; Madsen, CS; Monshizadegan, H; Ngu, K; Nguyen-Tran, V; Reeves, RA; Robl, JA; Ryan, CS; Search, D; Setters, R; Sitkoff, D; Stein, PD; Yin, X; Zahler, R; Zhang, R; Zhao, R; Zhuang, S1
Eda, T; Hidaka, Y; Kamei, T; Yonemoto, M1
Saheki, A; Tamai, I; Terasaki, T; Tsuji, A1
Abe, T; Nakagomi, R; Nakai, D; Sugiyama, Y; Tokui, T; Yawo, H1
Chen, C; Lin, J; Smolarek, T; Tremaine, L1
Barrett, DA; De Moor, CH; Gandhi, RD; Gershkovich, P; Hoo, CW; Lee, JB; Taha, DA1

Other Studies

7 other study(ies) available for pravastatin and simvastatin acid

ArticleYear
Differential interaction of 3-hydroxy-3-methylglutaryl-coa reductase inhibitors with ABCB1, ABCC2, and OATP1B1.
    Drug metabolism and disposition: the biological fate of chemicals, 2005, Volume: 33, Issue:4

    Topics: Adenosine Triphosphate; Animals; Atorvastatin; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line; Dogs; Estradiol; Fluoresceins; Heptanoic Acids; Hydrolysis; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Membrane Transport Proteins; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Organic Anion Transporters; Permeability; Pyrroles; Simvastatin; Structure-Activity Relationship

2005
(3R,5S,E)-7-(4-(4-fluorophenyl)-6-isopropyl-2-(methyl(1-methyl-1h-1,2,4-triazol-5-yl)amino)pyrimidin-5-yl)-3,5-dihydroxyhept-6-enoic acid (BMS-644950): a rationally designed orally efficacious 3-hydroxy-3-methylglutaryl coenzyme-a reductase inhibitor with
    Journal of medicinal chemistry, 2008, May-08, Volume: 51, Issue:9

    Topics: Administration, Oral; Animals; Biological Availability; Chemical and Drug Induced Liver Injury; Cholesterol; Crystallography, X-Ray; Dogs; Female; Guinea Pigs; Haplorhini; Humans; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Liver; Models, Molecular; Muscle Cells; Pyrimidines; Rats; Rats, Sprague-Dawley; Stereoisomerism; Structure-Activity Relationship; Triazoles

2008
Inhibition of cultured vascular smooth muscle cell migration by simvastatin (MK-733).
    Atherosclerosis, 1992, Volume: 95, Issue:1

    Topics: Animals; Anticholesteremic Agents; Aorta, Thoracic; Benzylamines; Cell Movement; Cells, Cultured; Dose-Response Relationship, Drug; Fibrinogen; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipoproteins, LDL; Lovastatin; Mevalonic Acid; Muscle, Smooth, Vascular; Nifedipine; Platelet-Derived Growth Factor; Pravastatin; Simvastatin; Sterols; Swine; Thiophenes

1992
Transport mechanism of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors at the blood-brain barrier.
    The Journal of pharmacology and experimental therapeutics, 1993, Volume: 267, Issue:3

    Topics: Acetates; Acetic Acid; Animals; Biological Transport; Blood-Brain Barrier; Brain; Carbon Radioisotopes; Cattle; Cells, Cultured; Endothelium, Vascular; Hydrogen-Ion Concentration; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Male; Perfusion; Pravastatin; Rats; Rats, Wistar; Sensitivity and Specificity; Simvastatin; Temperature

1993
Pravastatin, an HMG-CoA reductase inhibitor, is transported by rat organic anion transporting polypeptide, oatp2.
    Pharmaceutical research, 1999, Volume: 16, Issue:6

    Topics: Animals; Anion Transport Proteins; Biological Transport; Carbon Radioisotopes; Carrier Proteins; Cholates; Enzyme Inhibitors; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Oocytes; Pravastatin; Rats; Simvastatin; Xenopus laevis

1999
P-glycoprotein has differential effects on the disposition of statin acid and lactone forms in mdr1a/b knockout and wild-type mice.
    Drug metabolism and disposition: the biological fate of chemicals, 2007, Volume: 35, Issue:10

    Topics: Animals; Anticholesteremic Agents; Atorvastatin; ATP Binding Cassette Transporter, Subfamily B; ATP-Binding Cassette Sub-Family B Member 4; ATP-Binding Cassette Transporters; Brain; Heptanoic Acids; Lactones; Liver; Lovastatin; Male; Mice; Mice, Inbred Strains; Mice, Knockout; Pravastatin; Pyrroles; Simvastatin

2007
The role of acid-base imbalance in statin-induced myotoxicity.
    Translational research : the journal of laboratory and clinical medicine, 2016, Volume: 174

    Topics: Acid-Base Imbalance; Animals; Cell Death; Cell Differentiation; Cell Line; Cell Membrane Permeability; Chromatography, High Pressure Liquid; Culture Media; Humans; Hydrogen-Ion Concentration; Hydrolysis; Hydroxymethylglutaryl-CoA Reductase Inhibitors; L-Lactate Dehydrogenase; Membrane Transport Proteins; Mice; Microsomes, Liver; Muscle Development; Muscles; Plasma; Pravastatin; Simvastatin; Time Factors

2016