Compounds > pravastatin
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pravastatin and sesquiterpenes

pravastatin has been researched along with sesquiterpenes in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (25.00)18.2507
2000's8 (50.00)29.6817
2010's4 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Durham, SK; Flint, OP; Gregg, RE; Masters, BA1
Hirai, A; Kitagawa, M; Oeda, T; Saito, Y; Tanaka, T; Tatsuno, I; Yasuda, T1
Hirai, A; Kitagawa, M; Noguchi, Y; Saito, Y; Shiina, T; Tanaka, T; Tatsuno, I; Terano, T; Yasuda, T1
Hirai, A; Kitagawa, M; Kurakata, S; Nishimura, M; Saito, Y; Tanaka, T; Yamada, K; Yasuda, T1
Ikeda, U; Inaba, H; Ohki, R; Shimada, K; Shimpo, M; Takahashi, M; Yamamoto, K1
Alvarez, AM; García-Román, N; Lorenzo, MJ; Montes, A; Toro, MJ1
Eberlein, M; Goppelt-Struebe, M; Heusinger-Ribeiro, J1
Fujita, T; Izumo, N; Koida, M; Nakamuta, H1
Blum, HE; Spangenberg, HC; Thimme, R; Von Weizsäcker, F; Zuber-Jerger, I1
Asakage, M; Kaisaki, S; Kawai, K; Kitayama, J; Nagawa, H; Okaji, Y; Takahashi, K; Tsuno, NH; Yazawa, K1
Dellavalle, RP; Gendall, J; Kelly, D; Miller, L; Norris, DA; Ribble, D; Shellman, YG; Vanbuskirk, K1
Beales, IL; Ogunwobi, OO1
Brañes, J; Carvajal, J; Chen-Lin, K; Cuello, M; Gejman, R; Kato, S; Oliva, B; Owen, GI; Sadarangani, A; Smalley, S1
Fang, Y; Jaiseng, W; Kuno, T; Ma, Y; Takami, T; Zhou, X1
Alarcon, VB; Marikawa, Y1
Burale, S; Carson, RA; Chandran, UR; DeFranco, DB; Frahm, KA; Franks, AL; Monaghan, AP; Phan, JV; Rudine, AC; Silswal, N; Tally, SJ; Waldman, JK1

Reviews

1 review(s) available for pravastatin and sesquiterpenes

ArticleYear
[Systemic treatment for hepatocellular carcinoma].
    Zentralblatt fur Chirurgie, 2003, Volume: 128, Issue:11

    Topics: Adjuvants, Immunologic; Angiogenesis Inhibitors; Animals; Antibiotics, Antineoplastic; Anticholesteremic Agents; Antineoplastic Agents, Hormonal; Carcinoma, Hepatocellular; Chemoembolization, Therapeutic; Cyclohexanes; Disease Models, Animal; Genetic Therapy; Humans; Immunotherapy; Liver Neoplasms; Meta-Analysis as Topic; Mice; Multicenter Studies as Topic; O-(Chloroacetylcarbamoyl)fumagillol; Octreotide; Pilot Projects; Pravastatin; Primary Prevention; Prognosis; Randomized Controlled Trials as Topic; Risk Factors; Sesquiterpenes; Tamoxifen; Thymus Extracts; Time Factors

2003

Other Studies

15 other study(ies) available for pravastatin and sesquiterpenes

ArticleYear
HMG CoA reductase inhibitor-induced myotoxicity: pravastatin and lovastatin inhibit the geranylgeranylation of low-molecular-weight proteins in neonatal rat muscle cell culture.
    Toxicology and applied pharmacology, 1997, Volume: 145, Issue:1

    Topics: Animals; Animals, Newborn; Anticholesteremic Agents; Autoradiography; Cells, Cultured; Cholesterol; Densitometry; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Female; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Isotope Labeling; Lovastatin; Mevalonic Acid; Molecular Weight; Muscle Proteins; Muscle, Skeletal; Polyisoprenyl Phosphates; Pravastatin; Pregnancy; Protein Processing, Post-Translational; Rats; Rats, Sprague-Dawley; Scintillation Counting; Sesquiterpenes; Tritium

1997
Geranylgeranylpyrophosphate, a metabolite of mevalonate, regulates the cell cycle progression and DNA synthesis in human lymphocytes.
    Biochemical and biophysical research communications, 1997, Dec-18, Volume: 241, Issue:2

    Topics: Acyl Coenzyme A; Biological Transport; Cell Cycle; DNA; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Liposomes; Lymphocytes; Mevalonic Acid; Phytohemagglutinins; Polyisoprenyl Phosphates; Pravastatin; RNA, Messenger; Sesquiterpenes

1997
Geranylgeranylpyrophosphate plays a key role for the G1 to S transition in vascular smooth muscle cells.
    Journal of atherosclerosis and thrombosis, 1998, Volume: 5, Issue:1

    Topics: Animals; Biological Transport; Cell Division; Cells, Cultured; DNA; Dose-Response Relationship, Drug; Flow Cytometry; G1 Phase; GTP-Binding Proteins; Hemiterpenes; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunoblotting; Liposomes; Membrane Proteins; Muscle, Smooth, Vascular; Organophosphorus Compounds; Polyisoprenyl Phosphates; Pravastatin; Rats; rhoA GTP-Binding Protein; rhoB GTP-Binding Protein; S Phase; Sesquiterpenes

1998
Effect of pravastatin on type IV collagen secretion and mesangial cell proliferation.
    Kidney international. Supplement, 1999, Volume: 71

    Topics: Cell Cycle; Cell Division; Cells, Cultured; Collagen; DNA; Dose-Response Relationship, Drug; Gene Expression; Glomerular Mesangium; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Mevalonic Acid; Polyisoprenyl Phosphates; Pravastatin; RNA, Messenger; Sesquiterpenes

1999
Fluvastatin inhibits matrix metalloproteinase-1 expression in human vascular endothelial cells.
    Hypertension (Dallas, Tex. : 1979), 2000, Volume: 36, Issue:3

    Topics: Analysis of Variance; Anticholesteremic Agents; Dose-Response Relationship, Drug; Endothelium, Vascular; Fatty Acids, Monounsaturated; Fluvastatin; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indoles; Lovastatin; Matrix Metalloproteinase 1; Mevalonic Acid; Polyisoprenyl Phosphates; Pravastatin; Sesquiterpenes; Squalene; Time Factors; Tissue Inhibitor of Metalloproteinase-1

2000
Lovastatin induces apoptosis of spontaneously immortalized rat brain neuroblasts: involvement of nonsterol isoprenoid biosynthesis inhibition.
    Molecular and cellular neurosciences, 2001, Volume: 17, Issue:2

    Topics: Animals; Anticholesteremic Agents; Apoptosis; bcl-2-Associated X Protein; bcl-Associated Death Protein; bcl-X Protein; Carrier Proteins; Cell Division; Cell Line, Transformed; Cholesterol; Lovastatin; Mevalonic Acid; Neurons; Polyisoprenyl Phosphates; Pravastatin; Protein Prenylation; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Rats; Sesquiterpenes; Squalene; Stem Cells

2001
Rho-dependent inhibition of the induction of connective tissue growth factor (CTGF) by HMG CoA reductase inhibitors (statins).
    British journal of pharmacology, 2001, Volume: 133, Issue:7

    Topics: Actins; Blotting, Northern; Cell Line; Connective Tissue Growth Factor; Cytoskeleton; Dose-Response Relationship, Drug; Gene Expression Regulation; Growth Substances; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immediate-Early Proteins; Intercellular Signaling Peptides and Proteins; Lovastatin; Lysophospholipids; Mevalonic Acid; Polyisoprenyl Phosphates; Pravastatin; rho GTP-Binding Proteins; rhoA GTP-Binding Protein; RNA, Messenger; Sesquiterpenes; Simvastatin

2001
Lipophilic statins can be osteogenic by promoting osteoblastic calcification in a Cbfa1- and BMP-2-independent manner.
    Methods and findings in experimental and clinical pharmacology, 2001, Volume: 23, Issue:7

    Topics: Animals; Bone Morphogenetic Protein 2; Bone Morphogenetic Proteins; Calcification, Physiologic; Calcium; Cell Line; Core Binding Factor Alpha 1 Subunit; Core Binding Factors; Fatty Acids, Monounsaturated; Fluvastatin; GTPase-Activating Proteins; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunohistochemistry; Indoles; Lovastatin; Mevalonic Acid; Mice; Neoplasm Proteins; Osteoblasts; Osteogenesis; Phosphates; Polyisoprenyl Phosphates; Pravastatin; Protein Prenylation; Sesquiterpenes; Signal Transduction; Transcription Factors; Transforming Growth Factor beta; Tumor Cells, Cultured

2001
3-Hydroxy-3-methylglutaryl-coenzyme A reductase inhibitor (pravastatin) inhibits endothelial cell proliferation dependent on G1 cell cycle arrest.
    Anti-cancer drugs, 2004, Volume: 15, Issue:6

    Topics: Angiogenesis Inhibitors; Apoptosis; CDC2-CDC28 Kinases; Cell Division; Cells, Cultured; Cyclin D; Cyclin E; Cyclin-Dependent Kinase 2; Cyclins; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Endothelial Cells; Endothelium, Vascular; Extracellular Matrix; G1 Phase; Gene Expression; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Neovascularization, Pathologic; Polyisoprenyl Phosphates; Pravastatin; Randomized Controlled Trials as Topic; Sesquiterpenes; Umbilical Veins

2004
Lovastatin-induced apoptosis in human melanoma cell lines.
    Melanoma research, 2005, Volume: 15, Issue:2

    Topics: Animals; Anticholesteremic Agents; Apoptosis; Carcinoma, Squamous Cell; Caspase 3; Caspases; Cell Proliferation; Dimethylallyltranstransferase; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Melanoma; Mice; Polyisoprenyl Phosphates; Pravastatin; Sesquiterpenes

2005
Statins inhibit proliferation and induce apoptosis in Barrett's esophageal adenocarcinoma cells.
    The American journal of gastroenterology, 2008, Volume: 103, Issue:4

    Topics: Adenocarcinoma; Analysis of Variance; Animals; Apoptosis; Barrett Esophagus; Caspase 3; Cell Division; Cell Line, Tumor; Dose-Response Relationship, Drug; Esophageal Neoplasms; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunoblotting; Lovastatin; Mevalonic Acid; Nitrobenzenes; Polyisoprenyl Phosphates; Pravastatin; Protein Kinases; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sesquiterpenes; Signal Transduction; Simvastatin; Sulfonamides

2008
Lipophilic but not hydrophilic statins selectively induce cell death in gynaecological cancers expressing high levels of HMGCoA reductase.
    Journal of cellular and molecular medicine, 2010, Volume: 14, Issue:5

    Topics: Cell Death; Cell Line, Tumor; Cell Survival; Drug Resistance, Neoplasm; Drug Synergism; Epithelium; Female; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Genital Neoplasms, Female; Humans; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipids; Lovastatin; Mevalonic Acid; Ovarian Neoplasms; Polyisoprenyl Phosphates; Pravastatin; Sesquiterpenes; Signal Transduction; Simvastatin; Uterine Cervical Neoplasms; Water

2010
A genetic and pharmacological analysis of isoprenoid pathway by LC-MS/MS in fission yeast.
    PloS one, 2012, Volume: 7, Issue:11

    Topics: Antifungal Agents; Chromatography, Liquid; Ergosterol; HMGB1 Protein; Hydroxymethylglutaryl CoA Reductases; Lanosterol; Miconazole; Mutation; Naphthalenes; Polyisoprenyl Phosphates; Pravastatin; Schizosaccharomyces; Sesquiterpenes; Squalene; Sterols; Tandem Mass Spectrometry; Terbinafine

2012
Statins inhibit blastocyst formation by preventing geranylgeranylation.
    Molecular human reproduction, 2016, Volume: 22, Issue:5

    Topics: Adaptor Proteins, Signal Transducing; Animals; Benzamides; Blastocyst; Cell Cycle Proteins; Female; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Male; Mevalonic Acid; Mice; Phosphoproteins; Polyisoprenyl Phosphates; Pravastatin; Prenylation; Quinuclidines; Sesquiterpenes; YAP-Signaling Proteins

2016
Statins impact primary embryonic mouse neural stem cell survival, cell death, and fate through distinct mechanisms.
    PloS one, 2018, Volume: 13, Issue:5

    Topics: Animals; Autophagy; Biosynthetic Pathways; Cell Cycle; Cell Death; Cell Differentiation; Cell Survival; Cells, Cultured; Cholesterol; Female; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Mice; Mouse Embryonic Stem Cells; Neural Stem Cells; Polyisoprenyl Phosphates; Pravastatin; RNA, Messenger; Sesquiterpenes; Simvastatin; Sterol Regulatory Element Binding Protein 2; Transcriptome

2018