Page last updated: 2024-08-23

pravastatin and probucol

pravastatin has been researched along with probucol in 36 studies

Research

Studies (36)

TimeframeStudies, this research(%)All Research%
pre-19902 (5.56)18.7374
1990's20 (55.56)18.2507
2000's12 (33.33)29.6817
2010's1 (2.78)24.3611
2020's1 (2.78)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Itakura, H1
Arai, H; Hara, S; Ishii, K; Kita, T; Kume, N; Nagano, Y; Otani, H; Ueda, Y; Yokode, M1
Inoue, N; Itoh, H; Kishino, B; Koga, N; Nakashima, Y; Nishide, T; Okamura, K; Saito, Y; Tatami, R; Teramoto, T1
Mimura, K; Yukawa, S1
Kurota, M; Maeda, H; Matsuda, T; Miyaho, S; Morikawa, K; Nakai, T; Oida, K; Takahashi, S; Takai, H; Tamai, T1
Murase, T1
Arai, H; Ishii, K; Kawai, C; Kita, T; Kume, N; Nagano, Y; Otani, H; Ueda, Y; Yokode, M1
Saito, Y; Yoshida, S1
Baba, S; Inui, A; Iwai, M; Iwatani, I; Kasama, T; Kazumi, T; Otsuki, M; Uenoyama, R; Yokono, K; Yoshino, G1
Arakawa, K; Jimi, S; Liu, R; Matsuo, K; Saku, K; Yamamoto, K; Yanagita, T1
Arakawa, K; Bai, H; Hirata, K; Liu, R; Okura, Y; Saku, K; Zhang, B1
Ishikawa, T; Kagami, A; Manabe, M; Mochizuki, K; Moriguchi, EH; Nagano, M; Sakamoto, T; Tada, N1
Ikeda, T1
Aoyagi, S; Matsuzaki, M; Morikuni, C; Okada, K; Okuda, F; Ono, S; Tanaka, N; Tokisawa, I; Tomochika, Y; Wasaki, Y1
Daida, H; Lee, YJ; Miyano, H; Mokuno, H; Sakurai, H; Takaya, J; Yamaguchi, H; Yokoi, H1
Fujita, M; Shirai, K1
Jorge, PA1
Aragane, K; Kitamine, T; Kusunoki, J; Ohnishi, H; Yamaura, T1
Bräsen, JH; Harsch, M; Niendorf, A1
Hoshi, K; Ichihara, K; Yamamoto, A2
Harada, N; Kashiwagi, A; Kikkawa, R; Nishio, Y1
Chichibu, K; Inazu, A; Kajinami, K; Kiyohar, T; Koizumi, J; Mabuchi, H1
Bujo, H; Kobayashi, J; Matsunaga, A; Mori, S; Murano, S; Saito, Y; Sasaki, J; Takahashi, K; Yokote, K1
Iwasaki, K; Masuda, N; Morikawa, H; Nakashima, A; Ohtawa, M1
Iwasaki, K; Kuroda, N; Nakashima, A; Nakashima, K; Ohtawa, M; Wada, M1
Hayashi, J; Kashiwagi, S; Kinukawa, N; Koyanagi, S; Maeda, N; Sawayama, Y; Shimizu, C; Tatsukawa, M1
Aoyagi, S; Fujii, T; Hiromoto, M; Itoh, S; Matsuzaki, M; Tanaka, M; Toma, Y; Tomochika, Y; Umemoto, S1
Belenkov, YN; Kaminnyi, AI; Konovalova, GG; Kukharchuk, VV; Lankin, VZ; Pisarenko, OI; Shumaev, KB; Tikhaze, AK1
Hayashi, J; Kikuchi, K; Maeda, N; Okada, K; Sawayama, Y; Shimizu, C; Tatsukawa, M1
Makita, S; Oshima, K; Wajima, T1
Hayashi, J; Maeda, S; Ohnishi, H; Okada, K; Sawayama, Y1
Furusyo, N; Hayashi, J; Maeda, S; Ohnishi, H; Okada, K; Sawayama, Y1
Asada, A; Iwaki, H; Iwakiri, K; Kaneshiro, Y; Kobayashi, A; Masada, T; Oda, Y; Takaoka, K1
Cassola, N; Clezar, CN; Flumignan, CD; Flumignan, RL; Nakano, LC; Trevisani, VF1

Reviews

2 review(s) available for pravastatin and probucol

ArticleYear
[Endothelium, lipids and atherosclerosis].
    Arquivos brasileiros de cardiologia, 1997, Volume: 68, Issue:2

    Topics: Animals; Anticholesteremic Agents; Arteriosclerosis; Endocytosis; Endothelium, Vascular; Foam Cells; Humans; Hypercholesterolemia; Lipoproteins, LDL; Pravastatin; Probucol; Rabbits; Vitamin E

1997
Pharmacological interventions for asymptomatic carotid stenosis.
    The Cochrane database of systematic reviews, 2023, 08-04, Volume: 8

    Topics: Aspirin; Atherosclerosis; Atorvastatin; Carotid Stenosis; Chlorthalidone; Fluvastatin; Hemorrhage; Humans; Ischemic Stroke; Metoprolol; Pravastatin; Probucol; Rosuvastatin Calcium; Stroke; Warfarin

2023

Trials

9 trial(s) available for pravastatin and probucol

ArticleYear
Regression of coronary atherosclerosis by combined LDL-apheresis and lipid-lowering drug therapy in patients with familial hypercholesterolemia: a multicenter study. The LARS Investigators.
    Atherosclerosis, 1992, Volume: 95, Issue:1

    Topics: Adult; Blood Component Removal; Cholesterol, LDL; Combined Modality Therapy; Coronary Angiography; Coronary Artery Disease; Female; Humans; Hyperlipoproteinemia Type II; Lipids; Male; Middle Aged; Pravastatin; Probucol

1992
Combined therapy with probucol and pravastatin in hypercholesterolaemia. One year follow-up study.
    European journal of clinical pharmacology, 1993, Volume: 44, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Apolipoproteins; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hypercholesterolemia; Lipids; Lipoproteins; Male; Middle Aged; Phospholipids; Pravastatin; Probucol; Triglycerides

1993
Effectiveness of probucol in preventing restenosis after percutaneous transluminal coronary angioplasty.
    Japanese heart journal, 1996, Volume: 37, Issue:3

    Topics: Angioplasty, Balloon, Coronary; Anticholesteremic Agents; Coronary Artery Disease; Female; Humans; Male; Middle Aged; Pravastatin; Probucol; Prospective Studies; Recurrence

1996
A comparative study of the therapeutic effect of probucol and pravastatin on xanthelasma.
    The Journal of dermatology, 1996, Volume: 23, Issue:9

    Topics: Adult; Aged; Anticholesteremic Agents; Female; Follow-Up Studies; Humans; Male; Middle Aged; Pravastatin; Probucol; Skin Diseases; Treatment Outcome; Xanthomatosis

1996
Effects of cholesterol-lowering treatments on oxidative modification of plasma intermediate density lipoprotein plus low density lipoprotein fraction in Type 2 diabetic patients.
    Diabetes research and clinical practice, 1999, Volume: 43, Issue:2

    Topics: Anticholesteremic Agents; Apolipoproteins B; Blood Glucose; Body Mass Index; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Diabetes Mellitus, Type 2; Female; Humans; Hypercholesterolemia; Lipid Peroxidation; Lipid Peroxides; Lipoproteins; Lipoproteins, IDL; Lipoproteins, LDL; Male; Middle Aged; Phospholipids; Pravastatin; Probucol; Regression Analysis; Smoking; Time Factors; Triglycerides

1999
Effects of probucol and pravastatin on common carotid atherosclerosis in patients with asymptomatic hypercholesterolemia. Fukuoka Atherosclerosis Trial (FAST).
    Journal of the American College of Cardiology, 2002, Feb-20, Volume: 39, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Anticholesteremic Agents; Carotid Artery Diseases; Carotid Artery, Common; Female; Humans; Hypercholesterolemia; Japan; Lipoproteins; Male; Middle Aged; Pravastatin; Probucol; Remission Induction; Time Factors; Tunica Intima; Ultrasonography

2002
Association of Chlamydia pneumoniae antibody with the cholesterol-lowering effect of statins.
    Atherosclerosis, 2003, Volume: 171, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Angiography; Antibodies, Bacterial; Blotting, Western; Carotid Artery Diseases; Chlamydophila Infections; Chlamydophila pneumoniae; Disease Progression; Enzyme-Linked Immunosorbent Assay; Female; Follow-Up Studies; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunoglobulin A; Immunoglobulin G; Lipoproteins, LDL; Male; Middle Aged; Pravastatin; Probucol; Risk Assessment; Severity of Illness Index; Treatment Outcome

2003
Effect of probucol on elderly hypercholesterolemic patients in the FAST study.
    Fukuoka igaku zasshi = Hukuoka acta medica, 2006, Volume: 97, Issue:1

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Anticholesteremic Agents; Atherosclerosis; Cardiovascular Diseases; Carotid Arteries; Carotid Artery Diseases; Cohort Studies; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Incidence; Male; Middle Aged; Pravastatin; Probucol; Risk; Treatment Outcome

2006
Both hepatitis C virus and Chlamydia pneumoniae infection are related to the progression of carotid atherosclerosis in patients undergoing lipid lowering therapy.
    Fukuoka igaku zasshi = Hukuoka acta medica, 2006, Volume: 97, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Anticholesteremic Agents; Carotid Artery Diseases; Chlamydophila Infections; Chlamydophila pneumoniae; Disease Progression; Female; Hepatitis C; Humans; Male; Middle Aged; Pravastatin; Probucol

2006

Other Studies

25 other study(ies) available for pravastatin and probucol

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
[Treatment of hyperlipidemia].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1992, Nov-10, Volume: 81, Issue:11

    Topics: Blood Component Removal; Cholesterol, LDL; Cholestyramine Resin; Clofibrate; Coronary Disease; Dietary Fiber; Energy Intake; Female; Humans; Hyperlipidemias; Male; Niceritrol; Pravastatin; Probucol

1992
The role of oxidized lipoproteins in the pathogenesis of atherosclerosis.
    Clinical and experimental pharmacology & physiology. Supplement, 1992, Volume: 20

    Topics: Animals; Apolipoproteins B; Cholesterol Esters; Cholestyramine Resin; Coronary Artery Disease; Lipoproteins; Lipoproteins, HDL; Lipoproteins, LDL; Macrophages; Mice; Oxidation-Reduction; Pravastatin; Probucol; Rabbits; Receptors, LDL; RNA, Messenger

1992
[Hyperlipidemia and drug treatment].
    Nihon rinsho. Japanese journal of clinical medicine, 1991, Volume: 49 Suppl

    Topics: Arteriosclerosis; Carnitine; Cholestyramine Resin; Glomerulonephritis; Humans; Hyperlipidemias; Kidney Failure, Chronic; Niceritrol; Pantetheine; Pravastatin; Probucol; Vitamin E

1991
[A case of familial hypercholesterolemia associated with nephrotic syndrome].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1990, Aug-10, Volume: 79, Issue:8

    Topics: Cholestyramine Resin; Drug Therapy, Combination; Female; Heptanoic Acids; Humans; Hyperlipoproteinemia Type II; Middle Aged; Naphthalenes; Nephrotic Syndrome; Pravastatin; Prednisolone; Probucol

1990
[Hyperlipoproteinemia: classification and current problems].
    Nihon rinsho. Japanese journal of clinical medicine, 1990, Volume: 48, Issue:11

    Topics: Diet; Heptanoic Acids; Humans; Hyperlipoproteinemias; Lipoproteins; Naphthalenes; Pravastatin; Probucol; Specific Gravity

1990
Lipoproteins and atherosclerosis.
    Japanese circulation journal, 1990, Volume: 54, Issue:9

    Topics: Animals; Anticholesteremic Agents; Arteriosclerosis; Cholesterol; Cholesterol Esters; Cholestyramine Resin; Disease Models, Animal; Foam Cells; Heptanoic Acids; Hyperlipidemia, Familial Combined; Lipoproteins, LDL; Liver; Macrophages; Mice; Naphthalenes; Pravastatin; Probucol; Rabbits; Receptors, Cell Surface; Receptors, Lipoprotein

1990
[Recent trend in the research of hyperlipidemia in Japan. Treatment of refractory hyperlipidemia].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1989, Volume: 78, Issue:10

    Topics: Anticholesteremic Agents; Bezafibrate; Blood Component Removal; Cholesterol; Drug Therapy, Combination; Heptanoic Acids; Humans; Hyperlipoproteinemia Type I; Hyperlipoproteinemia Type II; Hyperlipoproteinemia Type V; Hyperlipoproteinemias; Naphthalenes; Pravastatin; Probucol; Triglycerides

1989
Probucol versus eptastatin in hypercholesterolaemic diabetics.
    Lancet (London, England), 1986, Sep-27, Volume: 2, Issue:8509

    Topics: Cholesterol, HDL; Diabetes Complications; Female; Heptanoic Acids; Humans; Hypercholesterolemia; Male; Naphthalenes; Phenols; Pravastatin; Probucol

1986
Combined effects of pravastatin and probucol on high-density lipoprotein apolipoprotein A-I kinetics in cholesterol-fed rabbits.
    Japanese circulation journal, 1995, Volume: 59, Issue:5

    Topics: Animals; Apolipoprotein A-I; Cholesterol; Cholesterol, Dietary; Cholesterol, HDL; Drug Synergism; Kinetics; Male; Pravastatin; Probucol; Rabbits

1995
Effects of probucol and pravastatin on plasma lipids, activities of postheparin lipoprotein lipase, and lecithin cholesterol acyltransferase and apo A-I containing lipoproteins with and without apo A-II in patients with moderate hypercholesterolemia.
    Clinical biochemistry, 1993, Volume: 26, Issue:2

    Topics: Apolipoprotein A-I; Apolipoprotein A-II; Cholesterol, HDL; Female; Humans; Hypercholesterolemia; Lipoprotein Lipase; Male; Middle Aged; Particle Size; Pravastatin; Probucol

1993
Marked decrease in serum HDL cholesterol levels by combined probucol-pravastatin treatment in hypercholesterolemic NIDDM patients.
    Diabetes care, 1993, Volume: 16, Issue:5

    Topics: Aged; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Female; Humans; Hypercholesterolemia; Middle Aged; Pravastatin; Probucol; Triglycerides

1993
Improvement of atherosclerosis and stiffness of the thoracic descending aorta with cholesterol-lowering therapies in familial hypercholesterolemia.
    Arteriosclerosis, thrombosis, and vascular biology, 1996, Volume: 16, Issue:8

    Topics: Adult; Anticholesteremic Agents; Aorta, Thoracic; Aortic Diseases; Arteriosclerosis; Echocardiography, Transesophageal; Elasticity; Female; Follow-Up Studies; Humans; Hyperlipoproteinemia Type II; Male; Middle Aged; Pravastatin; Probucol; Reproducibility of Results

1996
[Effect of F-1394, a potent and selective inhibitor of acyl-CoA:cholesterol acyltransferase (ACAT), on esterification of cholesterol and basolateral secretion of cholesteryl ester in Caco-2 cells].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1997, Volume: 110, Issue:6

    Topics: Anilides; Anticholesteremic Agents; Caco-2 Cells; Cholesterol; Cholesterol Esters; Clofibrate; Cyclohexanes; Dioxanes; Esterification; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Intestinal Mucosa; Phenylurea Compounds; Pravastatin; Probucol; Simvastatin; Sterol O-Acyltransferase

1997
Survival and cardiovascular pathology of heterozygous Watanabe heritable hyperlipidaemic rabbits treated with pravastatin and probucol on a low-cholesterol (0.03%)-enriched diet.
    Virchows Archiv : an international journal of pathology, 1998, Volume: 432, Issue:6

    Topics: Animals; Aorta; Cholesterol; Cholesterol, Dietary; Coronary Artery Disease; Drug Therapy, Combination; Female; Hyperlipidemias; Immunohistochemistry; Liver; Male; Pravastatin; Probucol; Rabbits; Survival Rate; Treatment Outcome

1998
Fluvastatin, an inhibitor of 3-hydroxy-3-methylglutaryl-CoA reductase, scavenges free radicals and inhibits lipid peroxidation in rat liver microsomes.
    European journal of pharmacology, 1998, Nov-13, Volume: 361, Issue:1

    Topics: Animals; Anticholesteremic Agents; Antioxidants; Butylated Hydroxytoluene; Cytochrome P-450 Enzyme System; Fatty Acids, Monounsaturated; Fluvastatin; Free Radical Scavengers; Hydroxyl Radical; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indoles; Lipid Peroxidation; Male; Microsomes, Liver; Pravastatin; Probucol; Rats; Rats, Sprague-Dawley; Superoxides

1998
Opposite effects on serum cholesteryl ester transfer protein levels between long-term treatments with pravastatin and probucol in patients with primary hypercholesterolemia and xanthoma.
    Atherosclerosis, 1999, Volume: 145, Issue:2

    Topics: Achilles Tendon; Adult; Aged; Anticholesteremic Agents; Carrier Proteins; Cholesterol Ester Transfer Proteins; Cholesterol, HDL; Enzyme-Linked Immunosorbent Assay; Female; Follow-Up Studies; Glycoproteins; Humans; Hyperlipoproteinemia Type II; Male; Middle Aged; Muscular Diseases; Pravastatin; Probucol; Tomography, X-Ray Computed; Treatment Outcome; Triglycerides; Xanthomatosis

1999
Marked decrease in plasma apolipoprotein A-I and high density lipoprotein-cholesterol in a case with Werner syndrome.
    Clinica chimica acta; international journal of clinical chemistry, 2000, Volume: 293, Issue:1-2

    Topics: Adult; Anticholesteremic Agents; Apolipoprotein A-I; Bezafibrate; Cholesterol, HDL; Humans; Hypolipidemic Agents; Lipoproteins, HDL; Male; Polymerase Chain Reaction; Polymorphism, Single-Stranded Conformational; Pravastatin; Probucol; Time Factors; Triglycerides; Werner Syndrome

2000
[Antioxidative effects of fluvastatin, and its major metabolites [II]].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2001, Volume: 121, Issue:1

    Topics: Animals; Anticholesteremic Agents; Cells, Cultured; Depression, Chemical; Fatty Acids, Monounsaturated; Fluvastatin; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indoles; Lipid Peroxidation; Microsomes, Liver; Pravastatin; Probucol; Simvastatin; Stereoisomerism; Structure-Activity Relationship

2001
Antioxidative effect of fluvastatin, an inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase, on peroxidation of phospholipid liposomes.
    The Journal of pharmacy and pharmacology, 2001, Volume: 53, Issue:2

    Topics: Antioxidants; Butylated Hydroxytoluene; Fatty Acids, Monounsaturated; Fluvastatin; Free Radicals; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indoles; Iron; Lipid Peroxidation; Liposomes; Oxidants; Oxygen Consumption; Phospholipids; Pravastatin; Probucol

2001
Inhibitory effects of fluvastain and its metabolites on the formation of several reactive oxygen species.
    Life sciences, 2001, Aug-10, Volume: 69, Issue:12

    Topics: Animals; Antioxidants; Fatty Acids, Monounsaturated; Fluvastatin; Free Radical Scavengers; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indoles; Microsomes, Liver; Oxygen; Pravastatin; Probucol; Rats; Reactive Oxygen Species; Simvastatin; Singlet Oxygen; Vitamin E

2001
Importance of NAD(P)H oxidase-mediated oxidative stress and contractile type smooth muscle myosin heavy chain SM2 at the early stage of atherosclerosis.
    Circulation, 2002, May-14, Volume: 105, Issue:19

    Topics: Actins; Animals; Anticholesteremic Agents; Antioxidants; Aorta, Thoracic; Arteriosclerosis; Cholesterol; Diet, Atherogenic; Disease Models, Animal; Elasticity; Hypercholesterolemia; Male; Membrane Transport Proteins; Muscle, Smooth, Vascular; Myosin Heavy Chains; NADH, NADPH Oxidoreductases; NADPH Dehydrogenase; NADPH Oxidases; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Oxidative Stress; Phosphoproteins; Pravastatin; Probucol; Protein Isoforms; Rabbits; Smooth Muscle Myosins; Superoxides

2002
Antioxidants decreases the intensification of low density lipoprotein in vivo peroxidation during therapy with statins.
    Molecular and cellular biochemistry, 2003, Volume: 249, Issue:1-2

    Topics: Animals; Antioxidants; Arteriosclerosis; Coenzymes; Dose-Response Relationship, Drug; Double-Blind Method; Enzyme Inhibitors; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipid Peroxidation; Lipoproteins, LDL; Liver; Male; Middle Aged; Oxidation-Reduction; Pravastatin; Probucol; Pyridines; Rats; Time Factors; Ubiquinone; Vitamin E

2003
Direct vascular effects of HR780, a novel 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor.
    Clinical and experimental pharmacology & physiology, 2003, Volume: 30, Issue:12

    Topics: Animals; Aorta, Thoracic; Cell Division; Cell Movement; Cells, Cultured; Dose-Response Relationship, Drug; Endothelial Cells; Fetal Blood; Hydroxymethylglutaryl-CoA Reductase Inhibitors; L-Lactate Dehydrogenase; Male; Mevalonic Acid; Muscle, Smooth, Vascular; Platelet-Derived Growth Factor; Pravastatin; Probucol; Pyridines; Rabbits; Simvastatin; Swine; Xanthine; Xanthine Oxidase

2003
Effect of simvastatin on steroid-induced osteonecrosis evidenced by the serum lipid level and hepatic cytochrome P4503A in a rabbit model.
    Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association, 2008, Volume: 13, Issue:5

    Topics: Animals; Cytochrome P-450 CYP3A; Female; Glucocorticoids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Lipids; Liver; Methylprednisolone; Osteonecrosis; Pravastatin; Probucol; Rabbits; Simvastatin

2008