Page last updated: 2024-08-23

pravastatin and phenyl acetate

pravastatin has been researched along with phenyl acetate in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19901 (8.33)18.7374
1990's8 (66.67)18.2507
2000's3 (25.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kalinowski, SS; Mosley, ST; Tanaka, RD1
Hasegawa, K; Koga, T; Kuroda, M; Shimada, Y; Tsujita, Y; Yamazaki, M1
Saito, Y; Shiki, Y; Shirai, K; Yoshida, S1
Hoshi, K; Ichihara, K; Itoh, S; Yamamoto, A1
Saheki, A; Tamai, I; Terasaki, T; Tsuji, A1
Inui, K; Nakano, T; Nanba, E; Ohno, K; Okada, S; Takeshita, K1
Arai, H; Cho, M; Doi, T; Jingami, H; Kita, T; Nagano, Y; Otani, H; Tanaka, M; Ueda, Y; Yokode, M1
Fuchs, M; Hörmann, E; Scheibner, J; Schiemann, M; Stange, EF; Tauber, G1
Kallien, G; Lange, K; Scheibner, J; Stange, EF1
Aldaghlas, TA; Berthold, HK; Holleran, AL; Kelleher, JK; Lindenthal, B; Sudhop, T; Von Bergmann, K1
Chan, P; Chen, YJ; Hsieh, MH; Hsu, FL; Lin, JY; Liu, JC; Lo, MY1
Fraser, H; Lusis, AJ; Shaposhnik, Z; Trias, J; Wang, X1

Trials

1 trial(s) available for pravastatin and phenyl acetate

ArticleYear
The pravastatin-induced decrease of biliary cholesterol secretion is not directly related to an inhibition of cholesterol synthesis in humans.
    Hepatology (Baltimore, Md.), 1999, Volume: 30, Issue:1

    Topics: Acetates; Adult; Anticholesteremic Agents; Carbon Isotopes; Cholesterol; Cholesterol, LDL; Cross-Over Studies; Double-Blind Method; Female; Gallbladder; Gas Chromatography-Mass Spectrometry; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Kinetics; Male; Placebos; Pravastatin

1999

Other Studies

11 other study(ies) available for pravastatin and phenyl acetate

ArticleYear
Effects of long-term administration of HMG-CoA reductase inhibitors on cholesterol synthesis in lens.
    Experimental eye research, 1991, Volume: 53, Issue:2

    Topics: Acetates; Animals; Cholesterol; Cricetinae; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lens, Crystalline; Liver; Lovastatin; Pravastatin; Rats; Rats, Inbred Strains; Simvastatin; Time Factors

1991
Tissue-selective inhibition of cholesterol synthesis in vivo by pravastatin sodium, a 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor.
    Biochimica et biophysica acta, 1990, Jul-16, Volume: 1045, Issue:2

    Topics: Acetates; Acetic Acid; Animals; Anticholesteremic Agents; Cells, Cultured; Cholesterol; Dose-Response Relationship, Drug; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Ileum; Kinetics; L Cells; Lens, Crystalline; Liver; Lovastatin; Male; Mice; Mice, Inbred C57BL; Naphthalenes; Pravastatin; Rats; Simvastatin; Spleen

1990
Effect of a new synthetic 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor on cholesterol synthesis and low density lipoprotein uptake by primary cultures of rat hepatocytes.
    Arzneimittel-Forschung, 1988, Volume: 38, Issue:2

    Topics: Acetates; Animals; Bile Acids and Salts; Cholesterol; Cholesterol Esters; Enzyme Inhibitors; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Lipoproteins, LDL; Liver; Male; Naphthalenes; Pravastatin; Rats; Rats, Inbred Strains

1988
Inhibition of cholesterol synthesis ex vivo and in vivo by fluvastatin, a new inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase.
    Experientia, 1995, Mar-15, Volume: 51, Issue:3

    Topics: Acetates; Animals; Anticholesteremic Agents; Carbon Radioisotopes; Cholesterol; Dose-Response Relationship, Drug; Fatty Acids, Monounsaturated; Fluvastatin; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Ileum; Indoles; Kidney; Kinetics; Liver; Male; Organ Specificity; Pravastatin; Rats; Rats, Wistar; Sterols

1995
Transport mechanism of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors at the blood-brain barrier.
    The Journal of pharmacology and experimental therapeutics, 1993, Volume: 267, Issue:3

    Topics: Acetates; Acetic Acid; Animals; Biological Transport; Blood-Brain Barrier; Brain; Carbon Radioisotopes; Cattle; Cells, Cultured; Endothelium, Vascular; Hydrogen-Ion Concentration; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Male; Perfusion; Pravastatin; Rats; Rats, Wistar; Sensitivity and Specificity; Simvastatin; Temperature

1993
Altered sensitivities to potential inhibitors of cholesterol biosynthesis in Niemann-Pick type C fibroblasts.
    Cell structure and function, 1993, Volume: 18, Issue:4

    Topics: Acetates; Adult; Amphotericin B; Anticholesteremic Agents; Cell Survival; Cells, Cultured; Cerulenin; Child; Cholecalciferol; Cholesterol; Cholesterol Esters; Fibroblasts; Filipin; Humans; Japan; Lipids; Male; Niemann-Pick Diseases; Pravastatin

1993
Regulation of apolipoprotein B production and secretion in response to the change of intracellular cholesteryl ester contents in rabbit hepatocytes.
    The Journal of biological chemistry, 1993, Jun-15, Volume: 268, Issue:17

    Topics: Acetates; Animals; Apolipoproteins B; Carbon Radioisotopes; Cells, Cultured; Cholesterol; Cholesterol Esters; Enzyme-Linked Immunosorbent Assay; Humans; Kinetics; Lipoproteins, LDL; Liver; Male; Pravastatin; Rabbits; RNA, Messenger

1993
Bile acid synthesis from newly synthesized vs. preformed cholesterol precursor pools in the rat.
    Hepatology (Baltimore, Md.), 1993, Volume: 17, Issue:6

    Topics: Acetates; Animals; Bile Acids and Salts; Chenodeoxycholic Acid; Cholesterol; Cholic Acid; Cholic Acids; Circadian Rhythm; Enterohepatic Circulation; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Kinetics; Male; Pravastatin; Protein Precursors; Rats; Rats, Wistar

1993
Isotopomer spectral analysis of intermediates of cholesterol synthesis in human subjects and hepatic cells.
    American journal of physiology. Endocrinology and metabolism, 2002, Volume: 282, Issue:6

    Topics: Acetates; Acetyl Coenzyme A; Carbon Isotopes; Carcinoma, Hepatocellular; Cholesterol; Duodenum; Gas Chromatography-Mass Spectrometry; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Isotope Labeling; Kinetics; Liver; Liver Neoplasms; Models, Biological; Pravastatin; Simvastatin; Tumor Cells, Cultured

2002
The in vitro inhibitory effects of crude extracts of traditional Chinese herbs on 3-hydroxy-3-methylglutaryl-coenzyme A reductase on Vero cells.
    The American journal of Chinese medicine, 2002, Volume: 30, Issue:4

    Topics: Acetates; Animals; Cell Division; Chlorocebus aethiops; Drugs, Chinese Herbal; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Mevalonic Acid; Plant Extracts; Pravastatin; Vero Cells

2002
The synergistic inhibition of atherogenesis in apoE-/- mice between pravastatin and the sPLA2 inhibitor varespladib (A-002).
    Journal of lipid research, 2009, Volume: 50, Issue:4

    Topics: Acetates; Animals; Apolipoproteins E; Aryldialkylphosphatase; Atherosclerosis; Drug Synergism; Enzyme Inhibitors; Indoles; Keto Acids; Lipids; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Phospholipases A2, Secretory; Pravastatin; Prodrugs

2009