pravastatin has been researched along with p-aminohippuric acid in 13 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 2 (15.38) | 18.2507 |
2000's | 6 (46.15) | 29.6817 |
2010's | 5 (38.46) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
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Endou, H; Hasegawa, M; Ito, K; Kusuhara, H; Sugiyama, D; Sugiyama, Y; Ueda, S | 1 |
Hori, S; Kikkawa, T; Mori, S; Ohtsuki, S; Otagiri, M; Takanaga, H; Terasaki, T | 1 |
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM | 1 |
Benet, LZ; Brouwer, KL; Chu, X; Dahlin, A; Evers, R; Fischer, V; Giacomini, KM; Hillgren, KM; Hoffmaster, KA; Huang, SM; Ishikawa, T; Keppler, D; Kim, RB; Lee, CA; Niemi, M; Polli, JW; Sugiyama, Y; Swaan, PW; Tweedie, DJ; Ware, JA; Wright, SH; Yee, SW; Zamek-Gliszczynski, MJ; Zhang, L | 1 |
Kouznetsova, VL; Nagle, MA; Nigam, SK; Tsigelny, IF | 1 |
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
Balletta, M; Bellinghieri, G; Bovino, M; Cianciaruso, B; Colucci, G; Conte, G; Dal Canton, A; Esposito, C; Fuiano, G; Rosa, M; Sepe, V | 1 |
Ishigami, M; Sugiyama, Y; Tokui, T; Yamazaki, M | 1 |
Kikuchi, R; Kusuhara, H; Sugiyama, D; Sugiyama, Y | 1 |
Deguchi, T; Endou, H; Kusuhara, H; Otagiri, M; Sugiyama, Y; Takadate, A | 1 |
Abe, T; Endou, H; Kikuchi, R; Kusuhara, H; Sugiyama, Y | 1 |
Izawa, S; Miyaji, T; Moriyama, Y; Omote, H; Togawa, N | 1 |
2 review(s) available for pravastatin and p-aminohippuric acid
Article | Year |
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Membrane transporters in drug development.
Topics: Animals; Computer Simulation; Decision Trees; Drug Approval; Drug Discovery; Drug Evaluation, Preclinical; Drug Interactions; Humans; Membrane Transport Proteins; Mice; Mice, Knockout; Prescription Drugs | 2010 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
1 trial(s) available for pravastatin and p-aminohippuric acid
Article | Year |
---|---|
Effects of hypercholesterolemia of renal hemodynamics: study in patients with nephrotic syndrome.
Topics: Adult; Anticholesteremic Agents; Female; Humans; Hypercholesterolemia; Inulin; Kidney Function Tests; Male; Middle Aged; Nephrotic Syndrome; p-Aminohippuric Acid; Pravastatin; Proteinuria; Renal Circulation; Single-Blind Method | 1996 |
10 other study(ies) available for pravastatin and p-aminohippuric acid
Article | Year |
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Functional involvement of rat organic anion transporter 3 (rOat3; Slc22a8) in the renal uptake of organic anions.
Topics: Algorithms; Animals; Anions; Blotting, Western; Fluorescent Antibody Technique; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Kidney; Kinetics; Ligands; LLC-PK1 Cells; Organic Anion Transporters, Sodium-Independent; p-Aminohippuric Acid; Penicillin G; Penicillins; Pravastatin; Rats; Rats, Sprague-Dawley; Swine | 2002 |
Mouse reduced in osteosclerosis transporter functions as an organic anion transporter 3 and is localized at abluminal membrane of blood-brain barrier.
Topics: Animals; Biological Transport; Blood-Brain Barrier; Capillaries; Disease Models, Animal; Estrone; Male; Membrane Transport Proteins; Mice; Mice, Inbred C57BL; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Osteosclerosis; Penicillin G; RNA, Messenger | 2004 |
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship | 2008 |
Elucidation of common pharmacophores from analysis of targeted metabolites transported by the multispecific drug transporter-Organic anion transporter1 (Oat1).
Topics: Animals; Cluster Analysis; Computer Simulation; Databases, Factual; Drug Design; Mice; Mice, Knockout; Organic Anion Transport Protein 1; Pharmaceutical Preparations; ROC Curve | 2011 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Tissue-selective uptake of pravastatin in rats: contribution of a specific carrier-mediated uptake system.
Topics: Animals; Carbon Radioisotopes; Chromatography, Thin Layer; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Half-Life; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Injections, Intravenous; Ion Transport; Isotope Labeling; Kidney; Liver; Male; p-Aminohippuric Acid; Pravastatin; Rats; Rats, Wistar; Sulfobromophthalein; Tissue Distribution | 1996 |
Contribution of organic anion transporter 3 (Slc22a8) to the elimination of p-aminohippuric acid and benzylpenicillin across the blood-brain barrier.
Topics: Animals; Biological Transport; Blood-Brain Barrier; Blotting, Western; Brain; Capillaries; Cimetidine; Drug Interactions; Enzyme Inhibitors; Immunohistochemistry; Male; Organic Anion Transporters, Sodium-Independent; p-Aminohippuric Acid; Penicillin G; Pravastatin; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Time Factors; Tritium | 2003 |
Characterization of uremic toxin transport by organic anion transporters in the kidney.
Topics: Animals; DNA, Complementary; GABA Modulators; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Kidney Tubules, Proximal; LLC-PK1 Cells; Male; Organ Culture Techniques; Organic Anion Transport Protein 1; Organic Anion Transporters, Sodium-Independent; p-Aminohippuric Acid; Penicillin G; Pravastatin; Rats; Rats, Sprague-Dawley; Swine; Toxins, Biological; Transfection; Uremia | 2004 |
Involvement of multiple transporters in the efflux of 3-hydroxy-3-methylglutaryl-CoA reductase inhibitors across the blood-brain barrier.
Topics: Animals; Blood-Brain Barrier; Brain; Carrier Proteins; Digoxin; DNA, Complementary; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Kinetics; Male; Microinjections; Organic Anion Transporters, Sodium-Independent; p-Aminohippuric Acid; Pravastatin; Quinolines; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Taurocholic Acid | 2004 |
A Na+-phosphate cotransporter homologue (SLC17A4 protein) is an intestinal organic anion exporter.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; Biological Transport; Humans; Intestine, Small; Male; Membrane Potentials; Mice; p-Aminohippuric Acid; Pravastatin; Proteolipids; Sodium-Phosphate Cotransporter Proteins, Type I; Uric Acid | 2012 |