Page last updated: 2024-08-23

pravastatin and nitrates

pravastatin has been researched along with nitrates in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (7.69)18.2507
2000's8 (61.54)29.6817
2010's4 (30.77)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Egashira, K; Takeshita, A1
Cittadino, M; Coelho, OR; Coelho-Filho, OR; De Luca, IM; Hyslop, S; Moreno Júnior, H; Sampaio, RC; Tanus-Santos, JE1
Egashira, K; Inoue, S; Kataoka, C; Kitamoto, S; Koyanagi, M; Ni, W; Takeshita, A1
Baiano, A; de Cristofaro, A; Del Forno, D; Giallauria, F; Paragliola, T; Rossi, M; Vigorito, C1
Caracchini, R; Colucci, M; Giannini, S; Gresele, P; Guglielmini, G; Momi, S; Monopoli, A; Ongini, E; Rossiello, MR; Semeraro, N1
Dever, G; Kennedy, S; Monopoli, A; Rush, C; Spickett, CM; Tennant, G; Wainwright, CL1
Cooper, AJ; Dusse, LM; Lwaleed, BA1
Campesi, I; Emanueli, C; Gadau, S; Kraenkel, N; Madeddu, P; Meloni, M; Monopoli, A; Ongini, E1
Benson, R; Dever, GJ; Kennedy, S; Spickett, CM; Wainwright, CL1
Bouchier-Hayes, D; Chan, F; Hanson, R; Laing, T1
Amoruso, A; Bardelli, C; Brunelleschi, S; Federici Canova, D; Fresu, LG; Ongini, E; Palma, A; Poletti, E; Zeng, HW1
D'Amico, M; Di Filippo, C; Monopoli, A; Ongini, E; Perretti, M1
Hayashi, A; Kubota, M; Nakayama, H; Okamura, M1

Reviews

1 review(s) available for pravastatin and nitrates

ArticleYear
Tissue factor and nitric oxide: a controversial relationship!
    Journal of thrombosis and thrombolysis, 2007, Volume: 23, Issue:2

    Topics: Animals; Anticoagulants; Aspirin; Blood Coagulation; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Nitrates; Nitric Oxide; Pravastatin; Thromboplastin; Up-Regulation

2007

Trials

1 trial(s) available for pravastatin and nitrates

ArticleYear
Beneficial effect of cholesterol-lowering therapy on endothelium-dependent coronary vasodilation in patients with hypercholesterolemia.
    Annals of the New York Academy of Sciences, 1995, Jan-17, Volume: 748

    Topics: Acetylcholine; Coronary Vessels; Female; Humans; Hypercholesterolemia; Male; Middle Aged; Nitrates; Papaverine; Pravastatin; Vasodilation

1995

Other Studies

11 other study(ies) available for pravastatin and nitrates

ArticleYear
Pravastatin reduces myocardial lesions induced by acute inhibition of nitric oxide biosynthesis in normocholesterolemic rats.
    International journal of cardiology, 2001, Volume: 79, Issue:2-3

    Topics: Analysis of Variance; Animals; Anticholesteremic Agents; Cardiomyopathies; Disease Models, Animal; Endothelium, Vascular; Enzyme Inhibitors; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Necrosis; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide Synthase; Nitrites; Pravastatin; Rats; Rats, Wistar; Thromboxane B2

2001
Antiinflammatory and antiarteriosclerotic actions of HMG-CoA reductase inhibitors in a rat model of chronic inhibition of nitric oxide synthesis.
    Circulation research, 2001, Aug-31, Volume: 89, Issue:5

    Topics: Animals; Anti-Inflammatory Agents; Arteriosclerosis; Blood Pressure; Chemokine CCL2; Coronary Vessels; Disease Models, Animal; Dose-Response Relationship, Drug; Gene Expression Regulation; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunohistochemistry; Lipids; Macrophages; Male; Monocytes; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide Synthase; Nitrites; Nitroarginine; Peptidyl-Dipeptidase A; Pravastatin; Proliferating Cell Nuclear Antigen; Pyridines; Rats; Rats, Inbred WKY; rhoA GTP-Binding Protein; RNA, Messenger; Systole; Transforming Growth Factor beta; Transforming Growth Factor beta1

2001
[Cardiac rehabilitation in a HIV-patient treated with protease inhibitors].
    Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace, 2003, Volume: 60, Issue:1

    Topics: Adult; Aspirin; Carbazoles; Carvedilol; Cholesterol; Coronary Angiography; Diet Therapy; Drug Therapy, Combination; Enalapril; Exercise Therapy; HIV Infections; Humans; Male; Myocardial Infarction; Nitrates; Pravastatin; Propanolamines; Protease Inhibitors; Treatment Outcome; Triglycerides

2003
A novel nitric oxide-releasing statin derivative exerts an antiplatelet/antithrombotic activity and inhibits tissue factor expression.
    Journal of thrombosis and haemostasis : JTH, 2005, Volume: 3, Issue:11

    Topics: Animals; Blood Platelets; Disease Models, Animal; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Inhibitory Concentration 50; Leukocytes, Mononuclear; Macrophages, Peritoneal; Male; Mice; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitrites; Nitro Compounds; P-Selectin; Platelet Adhesiveness; Platelet Aggregation; Pravastatin; Pulmonary Embolism; RNA, Messenger; Spleen; Thromboplastin

2005
The nitric oxide-donating pravastatin derivative, NCX 6550 [(1S-[1alpha(betaS*, deltaS*), 2alpha, 6alpha, 8beta-(R*), 8a alpha]]-1,2,6,7,8,8a-Hexahydro-beta, delta, 6-trihydroxy-2-methyl-8-(2-methyl-1-oxobutoxy)-1-naphtalene-heptanoic acid 4-(nitrooxy)but
    The Journal of pharmacology and experimental therapeutics, 2007, Volume: 320, Issue:1

    Topics: Animals; Apolipoproteins E; Atherosclerosis; Cell Adhesion; Chemokine CCL2; Cholesterol; Endothelium, Vascular; Female; Intercellular Adhesion Molecule-1; Male; Mice; Mice, Inbred C57BL; Nitrates; Nitric Oxide Donors; Pravastatin; Reactive Oxygen Species; Spleen; Thrombin

2007
Nitropravastatin stimulates reparative neovascularisation and improves recovery from limb Ischaemia in type-1 diabetic mice.
    British journal of pharmacology, 2007, Volume: 150, Issue:7

    Topics: Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Hindlimb; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension; Ischemia; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neovascularization, Physiologic; Nitrates; Nitric Oxide; Nitric Oxide Synthase Type III; Pravastatin

2007
Phospholipid chlorohydrin induces leukocyte adhesion to ApoE-/- mouse arteries via upregulation of P-selectin.
    Free radical biology & medicine, 2008, Feb-01, Volume: 44, Issue:3

    Topics: Animals; Anticholesteremic Agents; Apolipoproteins E; Arteries; Atherosclerosis; Cell Adhesion; Chlorohydrins; Hypochlorous Acid; Inflammation; Intercellular Adhesion Molecule-1; Leukocytes; Lipoproteins, LDL; Mice; Mice, Knockout; Nitrates; P-Selectin; Phosphatidylcholines; Phospholipids; Pravastatin; Reactive Oxygen Species; Up-Regulation

2008
Effect of pravastatin on experimental diabetic wound healing.
    The Journal of surgical research, 2010, Jun-15, Volume: 161, Issue:2

    Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hydroxyproline; Male; Nitrates; Nitric Oxide; Nitric Oxide Synthase Type III; Nitrites; Pravastatin; Rats; Rats, Sprague-Dawley; Skin; Wound Healing; Wounds and Injuries

2010
The nitric oxide-donating pravastatin, NCX 6550, inhibits cytokine release and NF-κB activation while enhancing PPARγ expression in human monocyte/macrophages.
    Pharmacological research, 2010, Volume: 62, Issue:5

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cytokines; Dose-Response Relationship, Drug; Humans; Interleukin-6; Macrophages; Mice; Monocytes; NF-kappa B; Nitrates; Nitric Oxide; Nitric Oxide Donors; PPAR gamma; Pravastatin; Superoxides; Tumor Necrosis Factor-alpha

2010
The cardio-protective properties of Ncx-6550, a nitric oxide donating pravastatin, in the mouse.
    Microcirculation (New York, N.Y. : 1994), 2010, Volume: 17, Issue:6

    Topics: Animals; Cardiotonic Agents; Heme Oxygenase-1; Hemodynamics; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Interleukin-1beta; Male; Mice; Mice, Inbred C57BL; Myocardial Infarction; Myocardial Reperfusion Injury; Nitrates; Nitric Oxide Donors; Nitrites; Pravastatin; Troponin I

2010
Complex formation with layered double hydroxides for the remediation of hygroscopicity.
    Chemical & pharmaceutical bulletin, 2015, Volume: 63, Issue:1

    Topics: Carbonates; Chlorides; Cyclohexanes; Drug Carriers; Hydroxides; Intercalating Agents; Nateglinide; Nitrates; Phenylalanine; Pravastatin; Wettability

2015