Page last updated: 2024-08-23

pravastatin and lathosterol

pravastatin has been researched along with lathosterol in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's7 (38.89)18.2507
2000's8 (44.44)29.6817
2010's3 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Miettinen, TA; Vanhanen, H1
Kesäniemi, YA; Miettinen, TA; Vanhanen, H1
Angelin, B; Berglund, L; Dallner, G; Elmberger, PG; Eriksson, M; Kalén, A; Lund, E; Reihnér, E1
Fujiyama, J; Kuriyama, M; Osame, M; Tokimura, Y; Utatsu, Y1
Colette, C; Crastes De Paulet, A; Descomps, B; Farnier, M; Feillet, C; Monnier, LH; Percheron, C1
Einarsson, K; Eriksson, M; Hillebrant, CG; Nyberg, B1
Braesen, JH; Gebhardt, A; Harsch, M; Lang, G; Löser, R; Niendorf, A; Reymann, A; Schliack, M1
Aldaghlas, TA; Berthold, HK; Holleran, AL; Kelleher, JK; Lindenthal, B; Sudhop, T; Von Bergmann, K1
Björkhem, I; Einarsson, C; Gustafsson, U; Hillebrant, CG; Nyberg, B; Rudling, M; Sahlin, S1
Clarenbach, JJ; Dotti, MT; Federico, A; Kelleher, JK; Lindenthal, B; von Bergmann, K1
Backman, JT; Eichelbaum, M; Hofmann, U; Kivistö, KT; Lütjohann, D; Neuvonen, PJ; Niemi, M; Schwab, M; von Bergmann, K1
Janatuinen, T; Knuuti, J; Laaksonen, R; Lehtimäki, T; Lütjohann, D; Thelen, KM; Vesalainen, R; von Bergmann, K1
Antikainen, M; Gylling, H; Hedman, M; Ketomäki, A; Miettinen, TA1
Gerloff, T; Johne, A; Lütjohann, D; Mwinyi, J; Roots, I; Schaefer, M; Sudhop, T; von Bergmann, K1
Arnold, KA; Eichelbaum, M; Hofmann, U; Igel, M; Kivistö, KT; Lütjohann, D; Niemi, M; Schwab, M; von Bergmann, K1
Buckley, BM; Ford, I; Jukema, JW; Lichtenstein, AH; Matthan, NR; Packard, C; Resteghini, N; Robertson, M; Schaefer, EJ; Shepherd, J1
Berthold, HK; Gouni-Berthold, I; Sudhop, T; von Bergmann, K1
Fukumoto, Y; Miura, M; Nochioka, K; Shiba, N; Shimokawa, H; Tanaka, S; Zhulanqiqige, do E1

Trials

8 trial(s) available for pravastatin and lathosterol

ArticleYear
Comparative effects of simvastatin and pravastatin on cholesterol synthesis in patients with primary hypercholesterolemia.
    Atherosclerosis, 1995, Volume: 118, Issue:2

    Topics: Adolescent; Adult; Aged; Anticholesteremic Agents; Apolipoproteins; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Cross-Over Studies; Double-Blind Method; Enzyme Inhibitors; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipoproteinemia Type II; Liver; Lovastatin; Male; Mevalonic Acid; Middle Aged; Pravastatin; Simvastatin; Treatment Outcome; Triglycerides

1995
Effects of combined treatment with pravastatin and ursodeoxycholic acid on hepatic cholesterol metabolism.
    European journal of clinical investigation, 2002, Volume: 32, Issue:7

    Topics: Adult; Aged; Anticholesteremic Agents; Bile; Case-Control Studies; Cholagogues and Choleretics; Cholelithiasis; Cholesterol; Cholesterol, LDL; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Pravastatin; Receptors, LDL; RNA, Messenger; Ursodeoxycholic Acid

2002
Effect of pravastatin on plasma sterols and oxysterols in men.
    European journal of clinical pharmacology, 2006, Volume: 62, Issue:1

    Topics: Adult; Brain; Cholesterol; Humans; Hydroxycholesterols; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Pravastatin; Sterols

2006
Serum noncholesterol sterols in children with heterozygous familial hypercholesterolemia undergoing pravastatin therapy.
    The Journal of pediatrics, 2006, Volume: 148, Issue:2

    Topics: Adolescent; Anticholesteremic Agents; Child; Cholestanol; Cholesterol; Desmosterol; Female; Heterozygote; Humans; Hyperlipoproteinemia Type II; Male; Phytosterols; Pravastatin; Sitosterols; Triglycerides

2006
Impact of the SLCO1B1 polymorphism on the pharmacokinetics and lipid-lowering efficacy of multiple-dose pravastatin.
    Clinical pharmacology and therapeutics, 2006, Volume: 79, Issue:5

    Topics: Adult; Area Under Curve; Cholesterol; Cholesterol, LDL; Half-Life; Haplotypes; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Liver-Specific Organic Anion Transporter 1; Organic Anion Transporters; Pharmacogenetics; Polymorphism, Genetic; Pravastatin; Prospective Studies

2006
Cholesterol absorption and synthesis markers in individuals with and without a CHD event during pravastatin therapy: insights from the PROSPER trial.
    Journal of lipid research, 2010, Volume: 51, Issue:1

    Topics: Aged; Aged, 80 and over; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Coronary Disease; Desmosterol; Female; Homeostasis; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Phytosterols; Pravastatin; Sitosterols; Triglycerides

2010
Lifibrol as a model compound for a novel lipid-lowering mechanism of action.
    Journal of cardiovascular pharmacology and therapeutics, 2010, Volume: 15, Issue:4

    Topics: Adult; Anticholesteremic Agents; Apolipoprotein B-100; Butanols; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Cholesterol, VLDL; Double-Blind Method; Humans; Hydroxybenzoates; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lipids; Lipoproteins, LDL; Male; Pravastatin; Triglycerides; Young Adult

2010
Ezetimibe improves endothelial function and inhibits Rho-kinase activity associated with inhibition of cholesterol absorption in humans.
    Circulation journal : official journal of the Japanese Circulation Society, 2012, Volume: 76, Issue:8

    Topics: Adult; Anticholesteremic Agents; Azetidines; Cholestanol; Cholesterol; Cross-Sectional Studies; Endothelium, Vascular; Ezetimibe; Female; Gene Expression Regulation, Enzymologic; Humans; Intestinal Absorption; Leukocytes; Male; Pravastatin; rho-Associated Kinases; Up-Regulation

2012

Other Studies

10 other study(ies) available for pravastatin and lathosterol

ArticleYear
Pravastatin and lovastatin similarly reduce serum cholesterol and its precursor levels in familial hypercholesterolaemia.
    European journal of clinical pharmacology, 1992, Volume: 42, Issue:2

    Topics: Adult; Aged; Cholesterol; Cholesterol, LDL; Desmosterol; Female; Humans; Hyperlipoproteinemia Type II; Isomerism; Lovastatin; Male; Middle Aged; Phytosterols; Pravastatin; Sitosterols; Triglycerides

1992
Pravastatin lowers serum cholesterol, cholesterol-precursor sterols, fecal steroids, and cholesterol absorption in man.
    Metabolism: clinical and experimental, 1992, Volume: 41, Issue:6

    Topics: Adult; Cholesterol; Feces; Female; Humans; Hyperlipoproteinemia Type II; Ileum; Intestinal Absorption; Male; Middle Aged; Pravastatin; Steroids; Sterols

1992
Effects of pravastatin and cholestyramine on products of the mevalonate pathway in familial hypercholesterolemia.
    Journal of lipid research, 1991, Volume: 32, Issue:6

    Topics: Adult; Aged; Cholesterol; Cholestyramine Resin; Dolichols; Drug Therapy, Combination; Female; Humans; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipoproteinemia Type II; Male; Mevalonic Acid; Middle Aged; Pravastatin; Ubiquinone

1991
Treatment of cerebrotendinous xanthomatosis: effects of chenodeoxycholic acid, pravastatin, and combined use.
    Journal of the neurological sciences, 1994, Volume: 125, Issue:1

    Topics: Adult; Apolipoproteins; Brain Diseases; Chenodeoxycholic Acid; Cholestanol; Cholesterol; Drug Therapy, Combination; Electrophysiology; Humans; Lipids; Lipoproteins; Male; Middle Aged; Muscular Diseases; Phytosterols; Pravastatin; Tendons; Xanthomatosis

1994
Changes in biliary lipid output after interruption of pravastatin treatment in humans.
    European journal of clinical investigation, 1996, Volume: 26, Issue:12

    Topics: Acyl Coenzyme A; Adult; Aged; Aged, 80 and over; Anticholesteremic Agents; Bile Acids and Salts; Cholesterol; Female; Humans; Isomerism; Lipoproteins; Liver; Male; Middle Aged; Pravastatin; Triglycerides

1996
Effects of pravastatin on cholesterol metabolism of cholesterol-fed heterozygous WHHL rabbits.
    British journal of pharmacology, 1998, Volume: 124, Issue:2

    Topics: Animals; Anticholesteremic Agents; Cholesterol; Cholesterol, Dietary; Heterozygote; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipoproteinemia Type II; Immunohistochemistry; Intestinal Absorption; Liver; Phytosterols; Polymerase Chain Reaction; Pravastatin; Rabbits; Receptors, LDL; RNA, Messenger

1998
Isotopomer spectral analysis of intermediates of cholesterol synthesis in human subjects and hepatic cells.
    American journal of physiology. Endocrinology and metabolism, 2002, Volume: 282, Issue:6

    Topics: Acetates; Acetyl Coenzyme A; Carbon Isotopes; Carcinoma, Hepatocellular; Cholesterol; Duodenum; Gas Chromatography-Mass Spectrometry; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Isotope Labeling; Kinetics; Liver; Liver Neoplasms; Models, Biological; Pravastatin; Simvastatin; Tumor Cells, Cultured

2002
Isotopomer spectral analysis of intermediates of cholesterol synthesis in patients with cerebrotendinous xanthomatosis.
    Metabolism: clinical and experimental, 2005, Volume: 54, Issue:3

    Topics: Adult; Bile; Bile Acids and Salts; Carbon Isotopes; Chenodeoxycholic Acid; Cholestanol; Cholestanols; Cholesterol; Female; Gas Chromatography-Mass Spectrometry; Humans; Isotope Labeling; Lanosterol; Male; Middle Aged; Pravastatin; Sterols; Xanthomatosis, Cerebrotendinous

2005
Acute effects of pravastatin on cholesterol synthesis are associated with SLCO1B1 (encoding OATP1B1) haplotype *17.
    Pharmacogenetics and genomics, 2005, Volume: 15, Issue:5

    Topics: Anticholesteremic Agents; Cholesterol; Female; Haplotypes; Humans; Liver-Specific Organic Anion Transporter 1; Male; Organic Anion Transporters; Polymorphism, Single Nucleotide; Pravastatin

2005
Influence of the SLCO1B1*1b and *5 haplotypes on pravastatin's cholesterol lowering capabilities and basal sterol serum levels.
    Naunyn-Schmiedeberg's archives of pharmacology, 2006, Volume: 373, Issue:1

    Topics: Adult; Anticholesteremic Agents; Cholesterol; Haplotypes; Humans; Liver-Specific Organic Anion Transporter 1; Male; Middle Aged; Organic Anion Transporters; Phytosterols; Pravastatin

2006