Compounds > pravastatin
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pravastatin and estrone sulfate

pravastatin has been researched along with estrone sulfate in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's8 (53.33)29.6817
2010's7 (46.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sugimoto, Y; Sugiyama, Y; Suzuki, H; Suzuki, M1
Imai, K; Kobayashi, D; Nezu, J; Nozawa, T; Tamai, I; Tsuji, A1
Imai, K; Nezu, J; Nozawa, T; Tamai, I; Tsuji, A1
Hori, S; Kikkawa, T; Mori, S; Ohtsuki, S; Otagiri, M; Takanaga, H; Terasaki, T1
Hirano, M; Kondo, C; Maeda, K; Matsushima, S; Sasaki, M; Sugiyama, Y; Suzuki, H1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Benet, LZ; Brouwer, KL; Chu, X; Dahlin, A; Evers, R; Fischer, V; Giacomini, KM; Hillgren, KM; Hoffmaster, KA; Huang, SM; Ishikawa, T; Keppler, D; Kim, RB; Lee, CA; Niemi, M; Polli, JW; Sugiyama, Y; Swaan, PW; Tweedie, DJ; Ware, JA; Wright, SH; Yee, SW; Zamek-Gliszczynski, MJ; Zhang, L1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Fent, K; Popovic, M; Smital, T; Zaja, R1
Brun, ME; Funk, C; Noé, J; Portmann, R1
Imai, S; Kitamura, A; Komuro, S; Yabuki, M1
Fromm, MF; Glaeser, H; König, J; Mandery, K; Sticht, H1
Chen, WQ; Chen, Y; Fan, L; Guo, CX; Li, Q; Qu, Q; Tan, ZR; Wang, G; Wu, LX; Yu, J; Zhang, W; Zhou, HH1
Li, L; Nouraldeen, A; Wilson, AG1

Reviews

1 review(s) available for pravastatin and estrone sulfate

ArticleYear
Membrane transporters in drug development.
    Nature reviews. Drug discovery, 2010, Volume: 9, Issue:3

    Topics: Animals; Computer Simulation; Decision Trees; Drug Approval; Drug Discovery; Drug Evaluation, Preclinical; Drug Interactions; Humans; Membrane Transport Proteins; Mice; Mice, Knockout; Prescription Drugs

2010

Trials

1 trial(s) available for pravastatin and estrone sulfate

ArticleYear
Inhibition of the organic anion-transporting polypeptide 1B1 by quercetin: an in vitro and in vivo assessment.
    British journal of clinical pharmacology, 2012, Volume: 73, Issue:5

    Topics: Antioxidants; Area Under Curve; Asian People; Cells, Cultured; Cross-Over Studies; Double-Blind Method; Drug Interactions; Estrogens; Estrone; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Liver-Specific Organic Anion Transporter 1; Male; Organic Anion Transporters; Pravastatin; Quercetin; Young Adult

2012

Other Studies

13 other study(ies) available for pravastatin and estrone sulfate

ArticleYear
ABCG2 transports sulfated conjugates of steroids and xenobiotics.
    The Journal of biological chemistry, 2003, Jun-20, Volume: 278, Issue:25

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Dehydroepiandrosterone Sulfate; Drug Resistance, Neoplasm; Humans; Kinetics; Lymphoma; Mice; Neoplasm Proteins; Recombinant Proteins; Steroids; Sulfuric Acids; Transfection; Tumor Cells, Cultured; Xenobiotics

2003
Involvement of human organic anion transporting polypeptide OATP-B (SLC21A9) in pH-dependent transport across intestinal apical membrane.
    The Journal of pharmacology and experimental therapeutics, 2003, Volume: 306, Issue:2

    Topics: Biological Transport; Carbon Radioisotopes; Cell Membrane; Cells, Cultured; Estrone; Humans; Hydrogen-Ion Concentration; Immunohistochemistry; Intestine, Small; Organic Anion Transporters; Pravastatin; Radiopharmaceuticals; Time Factors; Tritium

2003
Functional characterization of pH-sensitive organic anion transporting polypeptide OATP-B in human.
    The Journal of pharmacology and experimental therapeutics, 2004, Volume: 308, Issue:2

    Topics: Biological Transport; Cells, Cultured; Estrone; Humans; Hydrogen-Ion Concentration; Organic Anion Transporters

2004
Mouse reduced in osteosclerosis transporter functions as an organic anion transporter 3 and is localized at abluminal membrane of blood-brain barrier.
    The Journal of pharmacology and experimental therapeutics, 2004, Volume: 309, Issue:3

    Topics: Animals; Biological Transport; Blood-Brain Barrier; Capillaries; Disease Models, Animal; Estrone; Male; Membrane Transport Proteins; Mice; Mice, Inbred C57BL; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Osteosclerosis; Penicillin G; RNA, Messenger

2004
Identification of the hepatic efflux transporters of organic anions using double-transfected Madin-Darby canine kidney II cells expressing human organic anion-transporting polypeptide 1B1 (OATP1B1)/multidrug resistance-associated protein 2, OATP1B1/multid
    The Journal of pharmacology and experimental therapeutics, 2005, Volume: 314, Issue:3

    Topics: Amino Acid Sequence; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Bile; Dogs; Humans; Liver; Membrane Transport Proteins; Molecular Sequence Data; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Organic Anion Transporters; Protein Transport; Recombinant Proteins; Transfection

2005
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Molecular characterization of zebrafish Oatp1d1 (Slco1d1), a novel organic anion-transporting polypeptide.
    The Journal of biological chemistry, 2013, Nov-22, Volume: 288, Issue:47

    Topics: Animals; Evolution, Molecular; Glycosylation; Gonadal Steroid Hormones; HEK293 Cells; Humans; Ion Transport; Organic Anion Transporters; Protein Multimerization; Zebrafish; Zebrafish Proteins

2013
Substrate-dependent drug-drug interactions between gemfibrozil, fluvastatin and other organic anion-transporting peptide (OATP) substrates on OATP1B1, OATP2B1, and OATP1B3.
    Drug metabolism and disposition: the biological fate of chemicals, 2007, Volume: 35, Issue:8

    Topics: Animals; Anticholesteremic Agents; Biological Transport; Cell Line; CHO Cells; Chromans; Cricetinae; Cricetulus; Drug Interactions; Estrone; Fatty Acids, Monounsaturated; Fluvastatin; Gemfibrozil; Hepatocytes; Humans; Hypoglycemic Agents; Hypolipidemic Agents; Indoles; Kinetics; Liver-Specific Organic Anion Transporter 1; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Pravastatin; Protein Binding; Recombinant Proteins; Simvastatin; Solute Carrier Organic Anion Transporter Family Member 1B3; Taurocholic Acid; Thiazolidinediones; Troglitazone

2007
The new acyl-CoA cholesterol acyltransferase inhibitor SMP-797 does not interact with statins via OATP1B1 in human cryopreserved hepatocytes and oocytes expressing systems.
    Biopharmaceutics & drug disposition, 2007, Volume: 28, Issue:9

    Topics: Binding, Competitive; Biological Transport, Active; Cryopreservation; Cyclosporine; Dose-Response Relationship, Drug; Drug Interactions; Estrone; Fluorobenzenes; Hepatocytes; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Liver-Specific Organic Anion Transporter 1; Naphthyridines; Oocytes; Organic Anion Transporters; Pravastatin; Pyrimidines; Rosuvastatin Calcium; Sulfonamides

2007
Relevance of conserved lysine and arginine residues in transmembrane helices for the transport activity of organic anion transporting polypeptide 1B3.
    British journal of pharmacology, 2010, Feb-01, Volume: 159, Issue:3

    Topics: Alanine; Arginine; Biological Transport; Biological Transport, Active; Cell Membrane; Cellular Structures; Estrone; Glycine; Hepatocytes; Humans; Kinetics; Lysine; Organic Anion Transporters; Pharmaceutical Preparations; Pravastatin; Protein Structure, Secondary; Sulfobromophthalein

2010
Evaluation of transporter-mediated hepatic uptake in a non-radioactive high-throughput assay: a study of kinetics, species difference and plasma protein effect.
    Xenobiotica; the fate of foreign compounds in biological systems, 2013, Volume: 43, Issue:3

    Topics: Animals; Atorvastatin; Biological Assay; Biological Transport; Blood Proteins; Cells, Cultured; Cryopreservation; Estrone; Female; Hepatocytes; Heptanoic Acids; High-Throughput Screening Assays; Humans; Kinetics; Liver; Male; Metformin; Organic Anion Transporters; Pravastatin; Pyrroles; Radioactivity; Reproducibility of Results; Species Specificity; Time Factors

2013