pravastatin has been researched along with endothelin-1 in 18 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 11 (61.11) | 29.6817 |
| 2010's | 6 (33.33) | 24.3611 |
| 2020's | 1 (5.56) | 2.80 |
| Authors | Studies |
|---|---|
| Lee, TM; Su, SF; Tsai, CH | 1 |
| Akimoto, K; Asakawa, H; Horio, T; Matsuoka, H; Minamino, N; Mori, Y; Nishikimi, T; Tadokoro, K; Wang, X; Yoshihara, F | 1 |
| Chou, TF; Lee, TM; Tsai, CH | 1 |
| Fedak, PW; Li, RK; Li, SH; Miriuka, S; Rao, V; Verma, S; Weisel, RD | 1 |
| Chang, NC; Chou, TF; Lee, TM; Lin, MS; Tsai, CH | 1 |
| Cena, J; Das, D; Mraiche, F; Vollrath, B | 1 |
| Chang, NC; Lee, TM; Lin, MS; Tsai, CH | 1 |
| Chang, NC; Chou, TF; Lee, TM; Lin, MS | 1 |
| Hayashi, T; Ka, Y; Kitamura, A; Matsumura, Y; Mori, T; Ohkita, M; Sugii, M; Takaoka, M | 1 |
| Chang, NC; Chen, CC; Lee, TM; Shen, HN | 1 |
| Chang, NC; Chang, ST; Kang, CS; Lee, TM; Lin, CC | 1 |
| Chen, CC; Hsu, YJ; Lee, TM; Lien, HY; Lin, CC; Shih, CM | 1 |
| Gao, C; Li, L; Ma, L; Ren, Y; Wang, H; Yan, J; Yao, Y | 1 |
| Chang, CC; Huang, HC; Lee, FY; Lee, JY; Lee, SD; Lin, HC; Wang, SS | 1 |
| Ball, C; Beltrame, JF; Ghaffari, N; Kennedy, JA; Stafford, I | 1 |
| Kamata, K; Kobayashi, T; Matsumoto, T; Nemoto, S; Taguchi, K | 1 |
| Clark, JE; Garrett, N; Girardi, G; Pombo, J; Simmons, M; Umpierrez, M | 1 |
| Beard, S; Binder, NK; Brownfoot, FC; de Alwis, N; Hannan, NJ; Kaitu'u-Lino, TJ; Mangwiro, YT; Tong, S | 1 |
3 trial(s) available for pravastatin and endothelin-1
| Article | Year |
|---|---|
Effect of pravastatin on proteinuria in patients with well-controlled hypertension.
Topics: Adult; Double-Blind Method; Endothelin-1; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension; Lipids; Male; Middle Aged; Multivariate Analysis; Pravastatin; Prospective Studies; Proteinuria; Treatment Outcome | 2002 |
Add-on and withdrawal effect of pravastatin on proteinuria in hypertensive patients treated with AT receptor blockers.
Topics: Adult; Angiotensin II Type 1 Receptor Blockers; Drug Interactions; Drug Resistance; Endothelin-1; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension, Renal; Lipids; Losartan; Male; Middle Aged; Pravastatin; Proteinuria; Substance Withdrawal Syndrome | 2005 |
Effects of pravastatin on functional capacity in patients with chronic obstructive pulmonary disease and pulmonary hypertension.
Topics: Adult; Aged; Aged, 80 and over; Endothelin-1; Exercise Tolerance; Female; Hemodynamics; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension, Pulmonary; Lipids; Male; Middle Aged; Pravastatin; Pulmonary Disease, Chronic Obstructive; Treatment Outcome | 2009 |
15 other study(ies) available for pravastatin and endothelin-1
| Article | Year |
|---|---|
Cerivastatin, a hydroxymethylglutaryl coenzyme A reductase inhibitor, inhibits cardiac myocyte hypertrophy induced by endothelin.
Topics: ADP Ribose Transferases; Amides; Animals; Atrial Natriuretic Factor; Botulinum Toxins; Cell Size; Cells, Cultured; Endothelin-1; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Intracellular Signaling Peptides and Proteins; Mevalonic Acid; Myocytes, Cardiac; Phenylalanine; Polyisoprenyl Phosphates; Pravastatin; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Wistar; rho GTP-Binding Proteins; rho-Associated Kinases; RNA, Messenger | 2002 |
Effects of pravastatin on cardiomyocyte hypertrophy and ventricular vulnerability in normolipidemic rats after myocardial infarction.
Topics: Animals; Anti-Arrhythmia Agents; Cardiomyopathy, Hypertrophic; Cell Size; Cholesterol; Endothelin-1; Heart Ventricles; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunohistochemistry; Lipids; Male; Myocardial Infarction; Myocytes, Cardiac; Pravastatin; Rats; Rats, Wistar; RNA, Messenger; Up-Regulation; Ventricular Remodeling | 2003 |
Novel cardioprotective effects of pravastatin in human ventricular cardiomyocytes subjected to hypoxia and reoxygenation: beneficial effects of statins independent of endothelial cells.
Topics: Acyl Coenzyme A; Cardiotonic Agents; Cell Survival; Cells, Cultured; Child; Endothelin-1; Heart Ventricles; Humans; Hypoxia; Myocytes, Cardiac; Nitric Oxide; Oxygen; Pravastatin; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt | 2004 |
Effect of pravastatin on development of left ventricular hypertrophy in spontaneously hypertensive rats.
Topics: Animals; Body Weight; Cardiac Pacing, Artificial; Endothelin-1; Hemodynamics; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension; Hypertrophy, Left Ventricular; Immunohistochemistry; Male; Myocardium; Organ Size; Pravastatin; Rats; Rats, Inbred SHR; RNA, Messenger; Ventricular Function | 2005 |
Effects of statins on vascular function of endothelin-1.
Topics: Animals; Aorta; Cells, Cultured; Dogs; Endothelin-1; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Nucleic Acid Synthesis Inhibitors; Pravastatin; Rats; Rats, Sprague-Dawley; rho GTP-Binding Proteins; Simvastatin; Vasoconstriction | 2005 |
Additive effects of combined blockade of AT1 receptor and HMG-CoA reductase on left ventricular remodeling in infarcted rats.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Dose-Response Relationship, Drug; Drug Therapy, Combination; Endothelin-1; Gene Expression Regulation; Heart Ventricles; Hemodynamics; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertrophy, Left Ventricular; Imidazoles; Male; Myocardial Infarction; Pravastatin; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Tetrazoles; Ventricular Remodeling | 2006 |
Differential effects of different statins on endothelin-1 gene expression and endothelial NOS phosphorylation in porcine aortic endothelial cells.
Topics: Animals; Aorta; Atorvastatin; Cells, Cultured; Endothelial Cells; Endothelin-1; Endothelium, Vascular; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Nitric Oxide Synthase Type III; Phosphorylation; Pravastatin; Pyridines; Pyrroles; Quinolines; RNA, Messenger; Swine | 2006 |
Effect of pravastatin on nephroprotection in deoxycorticosterone acetate-salt hypertensive rats.
Topics: Animals; Base Sequence; Blood Pressure; Desoxycorticosterone; DNA Primers; Endothelin-1; Hypertension; Immunohistochemistry; Kidney; Male; Organ Size; Pravastatin; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sodium Chloride, Dietary | 2009 |
Effect of pravastatin on ventricular arrhythmias in infarcted rats: role of connexin43.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Blotting, Western; Bosentan; Cardiac Pacing, Artificial; Connexin 43; Disease Models, Animal; Drug Therapy, Combination; Endothelin Receptor Antagonists; Endothelin-1; Fluorescent Antibody Technique; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indoles; Male; Maleimides; Mevalonic Acid; Myocardial Infarction; Myocardium; Pravastatin; Protein Kinase C; Protein Kinase Inhibitors; Rats; Rats, Wistar; Receptors, Endothelin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sulfonamides; Time Factors; Ultrasonography | 2010 |
Pravastatin attenuates cardiac dysfunction induced by lysophosphatidylcholine in isolated rat hearts.
Topics: Animals; Creatine Kinase, MB Form; Endothelin-1; Heart; Heart Ventricles; Hemodynamics; L-Lactate Dehydrogenase; Lysophosphatidylcholines; Male; Pravastatin; Rats; Rats, Sprague-Dawley; Tachycardia; Ventricular Fibrillation | 2010 |
Pravastatin administration does not induce detrimental effects on hemodynamics and collaterals of portal hypertensive rats.
Topics: Animals; Collateral Circulation; Cyclooxygenase Inhibitors; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelin-1; Enzyme Inhibitors; Hemodynamics; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension, Portal; Indomethacin; Male; Nitric Oxide Synthase; Nitroarginine; Portal System; Pravastatin; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Time Factors; Vascular Resistance; Vasoconstriction; Vasoconstrictor Agents | 2010 |
Acute modulation of vasoconstrictor responses by pravastatin in small vessels.
Topics: Analysis of Variance; Animals; Dose-Response Relationship, Drug; Endothelial Cells; Endothelin B Receptor Antagonists; Endothelin-1; Enzyme Inhibitors; Free Radical Scavengers; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Male; Mesenteric Arteries; Myography; Nitric Oxide; Nitric Oxide Synthase; Pravastatin; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Receptor, Endothelin B; Signal Transduction; Superoxides; Vasoconstriction; Vasoconstrictor Agents; Vasodilator Agents | 2011 |
Pravastatin normalizes ET-1-induced contraction in the aorta of type 2 diabetic OLETF rats by suppressing the KSR1/ERK complex.
Topics: Animals; Aorta, Thoracic; Aortic Diseases; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelin-1; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phosphorylation; Pravastatin; Protein Kinases; Protein Phosphatase 2; Rats; Rats, Inbred OLETF; Signal Transduction; src-Family Kinases; Time Factors; Vasoconstriction; Vasoconstrictor Agents | 2012 |
Pravastatin therapy during preeclampsia prevents long-term adverse health effects in mice.
Topics: Animals; Cardiovascular Diseases; Disease Models, Animal; Endothelin-1; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension; Male; Mice; Mice, Inbred C57BL; Placenta; Pravastatin; Pre-Eclampsia; Pregnancy; Risk Factors; Vascular Remodeling | 2018 |
Pravastatin as the statin of choice for reducing pre-eclampsia-associated endothelial dysfunction.
Topics: Cell Survival; Cells, Cultured; Endothelin-1; Endothelium, Vascular; Female; Human Umbilical Vein Endothelial Cells; Humans; Pravastatin; Pre-Eclampsia; Pregnancy; Rosuvastatin Calcium; Simvastatin; Vascular Cell Adhesion Molecule-1; Vascular Endothelial Growth Factor Receptor-1 | 2020 |