Page last updated: 2024-08-23

pravastatin and d-alpha tocopherol

pravastatin has been researched along with d-alpha tocopherol in 24 studies

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's11 (45.83)18.2507
2000's9 (37.50)29.6817
2010's4 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Aviram, M; Brook, GJ; Hoffman, R1
Mimura, K; Yukawa, S1
Nyssönen, K; Porkkala-Sarataho, E; Salonen, JT; Salonen, R1
Belder, R; Nyyssönen, K; Park, JS; Porkkala, E; Rummukainen, J; Salonen, JT; Salonen, R1
Rouhiainen, H; Rouhiainen, P; Salonen, JT1
Nyyssönen, K; Porkkala-Sarataho, E; Salonen, JT1
Jorge, PA1
Chen, MF; Hsu, HC; Lee, YT1
Abete, P; Cacciatore, F; Chiariello, M; Chiariello, P; D'Armiento, FP; De Matteis, C; de Nigris, F; Di Loreto, M; Leccese, M; Liguori, A; Napoli, C; Palumbo, G; Somma, P; Zuliani, P1
Bláha, V; Brátová, M; Havel, E; Solichová, D; Zadák, Z1
Fujinami, T; Hibino, T; Jinno, Y; Kunimatsu, M; Okada, M; Sakuma, N; Sasai, K; Tamai, N; Yoshimata, T; Yosikawa, M1
Kersting, F; Selenka, A; Walch, S1
Iwasaki, K; Kuroda, N; Nakashima, A; Nakashima, K; Ohtawa, M; Wada, M1
Cole, WC; Kumar, B; Prasad, KN1
Belenkov, YN; Kaminnyi, AI; Konovalova, GG; Kukharchuk, VV; Lankin, VZ; Pisarenko, OI; Shumaev, KB; Tikhaze, AK1
Aleo, E; Dmitrieva, A; Littarru, GP; Passi, S; Stancato, A1
Nanayakkara, PW; Scheffer, PG; Stehouwer, CD; Teerlink, T; ter Wee, PM; Twisk, JW; van Dorp, W; van Guldener, C; van Ittersum, FJ1
Sylvester, PW; Wali, VB1
Blom, HJ; Kiefte-de Jong, JC; Kok, RM; Nanayakkara, PW; Olthof, MR; Smulders, YM; Stehouwer, CD; ter Wee, PM; van Guldener, C; van Ittersum, FJ1
Kiefte-de Jong, JC; Nanayakkara, PW; Olthof, MR; Smulders, YM; Stehouwer, CD; Teerlink, T; ter Wee, PM; Twisk, JW; van Guldener, C; van Ittersum, FJ1
Nanayakkara, PW; Smulders, YM; Stehouwer, CD; ter Wee, PM; van Guldener, C; van Ittersum, FJ; Vegting, IL; Veringa, SJ1
Adema, AY; de Borst, MH; Heijboer, AC; Hoenderop, JG; Nanayakkara, PW; Ter Wee, PM; van Ittersum, FJ; Vervloet, MG1

Reviews

2 review(s) available for pravastatin and d-alpha tocopherol

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
[Endothelium, lipids and atherosclerosis].
    Arquivos brasileiros de cardiologia, 1997, Volume: 68, Issue:2

    Topics: Animals; Anticholesteremic Agents; Arteriosclerosis; Endocytosis; Endothelium, Vascular; Foam Cells; Humans; Hypercholesterolemia; Lipoproteins, LDL; Pravastatin; Probucol; Rabbits; Vitamin E

1997

Trials

12 trial(s) available for pravastatin and d-alpha tocopherol

ArticleYear
The Kuopio Atherosclerosis Prevention Study (KAPS): effect of pravastatin treatment on lipids, oxidation resistance of lipoproteins, and atherosclerotic progression.
    The American journal of cardiology, 1995, Sep-28, Volume: 76, Issue:9

    Topics: Analysis of Variance; Anticholesteremic Agents; Arteriosclerosis; Carotid Artery Diseases; Double-Blind Method; Enzyme Inhibitors; Femoral Artery; Follow-Up Studies; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipid Peroxidation; Lipids; Lipoproteins; Lipoproteins, LDL; Lipoproteins, VLDL; Male; Oxidation-Reduction; Pravastatin; Ultrasonography; Vitamin E

1995
Kuopio Atherosclerosis Prevention Study (KAPS). A population-based primary preventive trial of the effect of LDL lowering on atherosclerotic progression in carotid and femoral arteries.
    Circulation, 1995, Oct-01, Volume: 92, Issue:7

    Topics: Anticholesteremic Agents; Arteriosclerosis; Carotid Artery Diseases; Carotid Artery, Common; Cholesterol, LDL; Cohort Studies; Double-Blind Method; Femoral Artery; Finland; Humans; Hypercholesterolemia; Intracranial Arteriosclerosis; Lipids; Male; Middle Aged; Pravastatin; Risk Factors; Smoking; Time Factors; Ultrasonography; Vitamin E

1995
Association between low plasma vitamin E concentration and progression of early cortical lens opacities.
    American journal of epidemiology, 1996, Sep-01, Volume: 144, Issue:5

    Topics: Adult; Anticholesteremic Agents; Arteriosclerosis; Cataract; Chromatography, High Pressure Liquid; Disease Progression; Finland; Humans; Linear Models; Male; Middle Aged; Pravastatin; Risk Factors; Time Factors; Vitamin E

1996
Increased oxidation resistance of atherogenic plasma lipoproteins at high vitamin E levels in non-vitamin E supplemented men.
    Atherosclerosis, 1996, Volume: 124, Issue:1

    Topics: Adult; Anticholesteremic Agents; Antioxidants; Arteriosclerosis; Ascorbic Acid; beta Carotene; Cholesterol, LDL; Copper; Dietary Fats; Double-Blind Method; Humans; Hypercholesterolemia; Linoleic Acid; Linoleic Acids; Lipids; Lipoproteins, LDL; Lipoproteins, VLDL; Male; Middle Aged; Oxidation-Reduction; Pravastatin; Risk Factors; Smoking; Vitamin E

1996
Short-term treatment with low-dose pravastatin attenuates oxidative susceptibility of low-density lipoprotein in hypercholesterolemic patients.
    Cardiovascular drugs and therapy, 1997, Volume: 11, Issue:6

    Topics: Adult; Female; Glutathione; Humans; Hypercholesterolemia; Hypolipidemic Agents; Kinetics; Lipids; Lipoproteins, LDL; Male; Oxidation-Reduction; Phenotype; Pravastatin; Thiobarbituric Acid Reactive Substances; Vitamin E

1997
Effects of vitamin E and HMG-CoA reductase inhibition on cholesteryl ester transfer protein and lecithin-cholesterol acyltransferase in hypercholesterolemia.
    Coronary artery disease, 1998, Volume: 9, Issue:5

    Topics: Antioxidants; Carrier Proteins; Cholesterol Ester Transfer Proteins; Combined Modality Therapy; Drug Therapy, Combination; Female; Glycoproteins; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Phosphatidylcholine-Sterol O-Acyltransferase; Pravastatin; Vitamin E

1998
Effects of cholestyramine on vitamin E levels in patients treated with statins.
    Journal of clinical pharmacology, 2000, Volume: 40, Issue:12 Pt 2

    Topics: Adult; Aged; Anticholesteremic Agents; Antioxidants; Cholesterol, LDL; Cholestyramine Resin; Drug Interactions; Fatty Acids, Monounsaturated; Female; Fluvastatin; Humans; Indoles; Lovastatin; Male; Middle Aged; Naphthalenes; Pravastatin; Simvastatin; Vitamin E

2000
Effect of a treatment strategy consisting of pravastatin, vitamin E, and homocysteine lowering on carotid intima-media thickness, endothelial function, and renal function in patients with mild to moderate chronic kidney disease: results from the Anti-Oxid
    Archives of internal medicine, 2007, Jun-25, Volume: 167, Issue:12

    Topics: Administration, Oral; Carotid Artery, Common; Double-Blind Method; Drug Therapy, Combination; Endothelium, Vascular; Enzyme-Linked Immunosorbent Assay; Female; Folic Acid; Follow-Up Studies; Glomerular Filtration Rate; Homocysteine; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Kidney Failure, Chronic; Male; Middle Aged; Oxidative Stress; Pravastatin; Pyridoxine; Retrospective Studies; Severity of Illness Index; Treatment Outcome; Ultrasonography; Vitamin E; Vitamins

2007
Association between global leukocyte DNA methylation, renal function, carotid intima-media thickness and plasma homocysteine in patients with stage 2-4 chronic kidney disease.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2008, Volume: 23, Issue:8

    Topics: Adult; Carotid Arteries; DNA Methylation; Double-Blind Method; Female; Glomerular Filtration Rate; Homocysteine; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Kidney Failure, Chronic; Leukocytes; Male; Middle Aged; Pravastatin; Tunica Intima; Vitamin B Complex; Vitamin E

2008
Randomized placebo-controlled trial assessing a treatment strategy consisting of pravastatin, vitamin E, and homocysteine lowering on plasma asymmetric dimethylarginine concentration in mild to moderate CKD.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2009, Volume: 53, Issue:1

    Topics: Adult; Aged; Anticholesteremic Agents; Arginine; Carotid Arteries; Chronic Disease; Creatinine; Double-Blind Method; Female; Folic Acid; Homocysteine; Humans; Kidney Diseases; Lipoproteins, LDL; Male; Middle Aged; Pravastatin; Vitamin B 12; Vitamin B 6; Vitamin E

2009
Effect of a treatment strategy consisting of pravastatin, vitamin E, and homocysteine lowering on arterial compliance and distensibility in patients with mild-to-moderate chronic kidney disease.
    Clinical nephrology, 2012, Volume: 78, Issue:4

    Topics: Adult; Aged; Brachial Artery; Carotid Artery, Common; Chronic Disease; Double-Blind Method; Female; Femoral Artery; Homocysteine; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Kidney Diseases; Male; Middle Aged; Pravastatin; Vascular Stiffness; Vitamin E

2012
Reduction of Oxidative Stress in Chronic Kidney Disease Does Not Increase Circulating α-Klotho Concentrations.
    PloS one, 2016, Volume: 11, Issue:1

    Topics: Adult; Aged; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antioxidants; Biomarkers; Female; Fibroblast Growth Factor-23; Fibroblast Growth Factors; Glomerular Filtration Rate; Glucuronidase; Humans; Klotho Proteins; Male; Middle Aged; Oxidative Stress; Pravastatin; Renal Insufficiency, Chronic; Renin-Angiotensin System; Vitamin E; Young Adult

2016

Other Studies

10 other study(ies) available for pravastatin and d-alpha tocopherol

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Hypolipidemic drugs reduce lipoprotein susceptibility to undergo lipid peroxidation: in vitro and ex vivo studies.
    Atherosclerosis, 1992, Volume: 93, Issue:1-2

    Topics: Adult; Animals; Bezafibrate; Cells, Cultured; Cholesterol; Cholesterol, LDL; Cholestyramine Resin; Esterification; Female; Humans; Hypercholesterolemia; Hypolipidemic Agents; Lipid Peroxidation; Lipoproteins, LDL; Macrophages; Male; Malondialdehyde; Mice; Middle Aged; Pravastatin; Vitamin E

1992
[Hyperlipidemia and drug treatment].
    Nihon rinsho. Japanese journal of clinical medicine, 1991, Volume: 49 Suppl

    Topics: Arteriosclerosis; Carnitine; Cholestyramine Resin; Glomerulonephritis; Humans; Hyperlipidemias; Kidney Failure, Chronic; Niceritrol; Pantetheine; Pravastatin; Probucol; Vitamin E

1991
Hypocholesterolemic effect of pravastatin is associated with increased content of antioxidant vitamin-E in cholesterol fractions.
    Acta medica (Hradec Kralove), 1998, Volume: 41, Issue:2

    Topics: Adult; Aged; Anticholesteremic Agents; Antioxidants; Cholesterol; Cholesterol, LDL; Female; Humans; Hyperlipoproteinemia Type II; Male; Middle Aged; Pravastatin; Vitamin E

1998
alpha-tocopherol protects the peroxidative modification of LDL to be recognized by LDL receptors.
    Journal of nutritional science and vitaminology, 1998, Volume: 44, Issue:5

    Topics: Adult; Cholesterol, LDL; Copper; Humans; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipid Peroxidation; Lipid Peroxides; Lipoproteins, LDL; Lymphocytes; Mevalonic Acid; Pravastatin; Receptors, LDL; Vitamin E

1998
Inhibitory effects of fluvastain and its metabolites on the formation of several reactive oxygen species.
    Life sciences, 2001, Aug-10, Volume: 69, Issue:12

    Topics: Animals; Antioxidants; Fatty Acids, Monounsaturated; Fluvastatin; Free Radical Scavengers; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indoles; Microsomes, Liver; Oxygen; Pravastatin; Probucol; Rats; Reactive Oxygen Species; Simvastatin; Singlet Oxygen; Vitamin E

2001
Alpha tocopheryl succinate, retinoic acid and polar carotenoids enhanced the growth-inhibitory effect of a cholesterol-lowering drug on immortalized and transformed nerve cells in culture.
    Journal of the American College of Nutrition, 2001, Volume: 20, Issue:6

    Topics: Animals; Anticholesteremic Agents; Antineoplastic Agents; Antioxidants; Carotenoids; Cell Line, Transformed; Cells, Cultured; Chromatography, High Pressure Liquid; Lovastatin; Mice; Neurons; Pravastatin; Rats; Tocopherols; Tretinoin; Vitamin E

2001
Antioxidants decreases the intensification of low density lipoprotein in vivo peroxidation during therapy with statins.
    Molecular and cellular biochemistry, 2003, Volume: 249, Issue:1-2

    Topics: Animals; Antioxidants; Arteriosclerosis; Coenzymes; Dose-Response Relationship, Drug; Double-Blind Method; Enzyme Inhibitors; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipid Peroxidation; Lipoproteins, LDL; Liver; Male; Middle Aged; Oxidation-Reduction; Pravastatin; Probucol; Pyridines; Rats; Time Factors; Ubiquinone; Vitamin E

2003
Statins lower plasma and lymphocyte ubiquinol/ubiquinone without affecting other antioxidants and PUFA.
    BioFactors (Oxford, England), 2003, Volume: 18, Issue:1-4

    Topics: Antioxidants; Atorvastatin; Catalase; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Coenzymes; Erythrocytes; Fatty Acids, Unsaturated; Glutathione; Glutathione Peroxidase; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Lymphocytes; Male; Middle Aged; Pravastatin; Pyrroles; Simvastatin; Superoxide Dismutase; Ubiquinone; Vitamin E

2003
Synergistic antiproliferative effects of gamma-tocotrienol and statin treatment on mammary tumor cells.
    Lipids, 2007, Volume: 42, Issue:12

    Topics: Animals; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Chromans; Dose-Response Relationship, Drug; Drug Synergism; Female; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Mammary Neoplasms, Animal; MAP Kinase Kinase 4; Mice; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pravastatin; Proto-Oncogene Proteins c-akt; Simvastatin; Vitamin E

2007