Page last updated: 2024-08-23

pravastatin and clofibrate

pravastatin has been researched along with clofibrate in 25 studies

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's7 (28.00)18.2507
2000's10 (40.00)29.6817
2010's8 (32.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bilter, GK; Dias, J; Huang, Z; Keon, BH; Lamerdin, J; MacDonald, ML; Michnick, SW; Minami, T; Owens, S; Shang, Z; Westwick, JK; Yu, H1
Andricopulo, AD; Moda, TL; Montanari, CA1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Campillo, NE; Guerra, A; Páez, JA1
Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Fent, K; Popovic, M; Smital, T; Zaja, R1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y1
Itakura, H1
Shepherd, J1
Bambauer, R; Müller, UA; Schiel, R1
Alonso-Galicia, M; Roman, RJ; Wilson, TW1
Aragane, K; Kitamine, T; Kusunoki, J; Ohnishi, H; Yamaura, T1
Pritzker, LB1
Haffner, SM1
Steiner, G1
Hampson, JP; Harvey, JN; Rizvi, K1
de Boer, A; Fishman, PA; Heckbert, SR; Klungel, OH; Leufkens, HG; Psaty, BM; Sullivan, SD; Veenstra, DL1
Gillies, C; Manktelow, B; Potter, JF1
Bouzamondo, A; Corvol, JC; Hulot, JS; Lechat, P; Sanchez, P; Sirol, M1
Dellavalle, RP; Drake, AL; Freeman, SR; Graber, M; Heilig, LF; McNealy, K; Schilling, LM1
Iwano, C; Matsuyama, K; Matzno, S; Tomiyama, N; Yasuda, N1

Reviews

8 review(s) available for pravastatin and clofibrate

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Fibrates and statins in the treatment of hyperlipidaemia: an appraisal of their efficacy and safety.
    European heart journal, 1995, Volume: 16, Issue:1

    Topics: Clinical Trials as Topic; Clofibrate; Drug Therapy, Combination; Humans; Hyperlipidemias; Lovastatin; Pravastatin; Retrospective Studies; Simvastatin

1995
Do lipid lowering drugs reduce the risk of coronary heart disease?
    Critical reviews in clinical laboratory sciences, 1998, Volume: 35, Issue:6

    Topics: Angiography; Anticholesteremic Agents; Clinical Trials as Topic; Clofibrate; Coronary Artery Disease; Coronary Disease; Europe; Humans; Hypolipidemic Agents; Lipoproteins, LDL; Pravastatin; Survival Rate

1998
The use of fibrates and of statins in preventing atherosclerosis in diabetes.
    Current opinion in lipidology, 2001, Volume: 12, Issue:6

    Topics: Anticholesteremic Agents; Arteriosclerosis; Clinical Trials as Topic; Clofibrate; Diabetes Complications; Diabetes Mellitus; Humans; Hypolipidemic Agents; Pravastatin; Simvastatin

2001
Do lipid-lowering drugs cause erectile dysfunction? A systematic review.
    Family practice, 2002, Volume: 19, Issue:1

    Topics: Adult; Clofibrate; Erectile Dysfunction; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Male; Pravastatin

2002
Interventions in the management of serum lipids for preventing stroke recurrence.
    The Cochrane database of systematic reviews, 2002, Issue:3

    Topics: Cardiovascular Diseases; Clofibrate; Estrogens, Conjugated (USP); Humans; Hypolipidemic Agents; Pravastatin; Recurrence; Stroke

2002
Differential effects of lipid-lowering therapies on stroke prevention: a meta-analysis of randomized trials.
    Archives of internal medicine, 2003, Mar-24, Volume: 163, Issue:6

    Topics: Anticholesteremic Agents; Atorvastatin; Cholestyramine Resin; Clofibrate; Colestipol; Gemfibrozil; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Myocardial Infarction; Pravastatin; Pyrroles; Randomized Controlled Trials as Topic; Regression Analysis; Risk Assessment; Risk Factors; Simvastatin; Stroke; Treatment Failure; Treatment Outcome

2003
Statins, fibrates, and melanoma risk: a systematic review and meta-analysis.
    Journal of the National Cancer Institute, 2006, Nov-01, Volume: 98, Issue:21

    Topics: Atorvastatin; Bezafibrate; Clofibrate; Gemfibrozil; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Incidence; Lovastatin; Melanoma; Odds Ratio; Pravastatin; Pyrroles; Randomized Controlled Trials as Topic; Reproducibility of Results; Simvastatin; Skin Neoplasms; United States

2006

Trials

1 trial(s) available for pravastatin and clofibrate

ArticleYear
Four years' treatment efficacy of patients with severe hyperlipidemia. Lipid lowering drugs versus LDL-apheresis.
    The International journal of artificial organs, 1995, Volume: 18, Issue:12

    Topics: Adolescent; Adult; Anticholesteremic Agents; Blood Component Removal; Cholesterol, HDL; Cholesterol, LDL; Cholestyramine Resin; Clofibrate; Colestipol; Coronary Disease; Enzyme-Linked Immunosorbent Assay; Female; Fenofibrate; Gemfibrozil; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Hypolipidemic Agents; Longitudinal Studies; Lovastatin; Male; Middle Aged; Niacin; Pravastatin; Quality of Life

1995

Other Studies

16 other study(ies) available for pravastatin and clofibrate

ArticleYear
Identifying off-target effects and hidden phenotypes of drugs in human cells.
    Nature chemical biology, 2006, Volume: 2, Issue:6

    Topics: Bacterial Proteins; Cell Line; Cell Proliferation; Cluster Analysis; Drug Design; Drug Evaluation, Preclinical; Genetics; Humans; Luminescent Proteins; Molecular Structure; Phenotype; Recombinant Fusion Proteins; Signal Transduction; Structure-Activity Relationship

2006
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
Prediction of drug intestinal absorption by new linear and non-linear QSPR.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:1

    Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics

2011
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Molecular characterization of zebrafish Oatp1d1 (Slco1d1), a novel organic anion-transporting polypeptide.
    The Journal of biological chemistry, 2013, Nov-22, Volume: 288, Issue:47

    Topics: Animals; Evolution, Molecular; Glycosylation; Gonadal Steroid Hormones; HEK293 Cells; Humans; Ion Transport; Organic Anion Transporters; Protein Multimerization; Zebrafish; Zebrafish Proteins

2013
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
    Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16

    Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone

2016
[Treatment of hyperlipidemia].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1992, Nov-10, Volume: 81, Issue:11

    Topics: Blood Component Removal; Cholesterol, LDL; Cholestyramine Resin; Clofibrate; Coronary Disease; Dietary Fiber; Energy Intake; Female; Humans; Hyperlipidemias; Male; Niceritrol; Pravastatin; Probucol

1992
Effects of lipid-lowering agents in the Dahl salt-sensitive rat.
    Hypertension (Dallas, Tex. : 1979), 1998, Volume: 31, Issue:1 Pt 2

    Topics: Animals; Blood Pressure; Cholesterol; Clofibrate; Cytochrome P-450 CYP4A; Cytochrome P-450 Enzyme System; Diet, Sodium-Restricted; Enzyme Induction; Female; Fenofibrate; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension; Hypolipidemic Agents; Kidney; Kidney Glomerulus; Male; Mixed Function Oxygenases; Pravastatin; Proteinuria; Rats; Rats, Inbred Strains; Sodium, Dietary; Triglycerides; Weight Gain

1998
[Effect of F-1394, a potent and selective inhibitor of acyl-CoA:cholesterol acyltransferase (ACAT), on esterification of cholesterol and basolateral secretion of cholesteryl ester in Caco-2 cells].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1997, Volume: 110, Issue:6

    Topics: Anilides; Anticholesteremic Agents; Caco-2 Cells; Cholesterol; Cholesterol Esters; Clofibrate; Cyclohexanes; Dioxanes; Esterification; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Intestinal Mucosa; Phenylurea Compounds; Pravastatin; Probucol; Simvastatin; Sterol O-Acyltransferase

1997
Secondary prevention of coronary heart disease: the role of fibric acids.
    Circulation, 2000, Jul-04, Volume: 102, Issue:1

    Topics: Anticholesteremic Agents; Clofibrate; Coronary Disease; Humans; Pravastatin

2000
Cholesterol-lowering drugs. Some drugs with demonstrated efficacy but different benefits in primary and secondary prevention.
    Prescrire international, 1999, Volume: 8, Issue:42

    Topics: Anticholesteremic Agents; Bezafibrate; Cholestyramine Resin; Clinical Trials as Topic; Clofibrate; Female; Gemfibrozil; Humans; Hypercholesterolemia; Lovastatin; Male; Myocardial Infarction; Pravastatin; Treatment Outcome

1999
Lipid-lowering drug use and cardiovascular events after myocardial infarction.
    The Annals of pharmacotherapy, 2002, Volume: 36, Issue:5

    Topics: Cholesterol; Clofibrate; Cohort Studies; Coronary Artery Disease; Coronary Disease; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Hypolipidemic Agents; Male; Middle Aged; Myocardial Infarction; Niacin; Pravastatin; Risk Factors; Simvastatin; Stroke; Treatment Outcome

2002
Flow cytometric evaluation of synergistic pro-apoptotic effects of statins and clofibrates in IM-9 human lymphoblasts.
    Clinical and experimental pharmacology & physiology, 2007, Volume: 34, Issue:9

    Topics: Antineoplastic Agents; Apoptosis; Atorvastatin; Caspase 3; Cell Line; Clofibrate; DNA Fragmentation; Drug Synergism; Enzyme Activation; Flow Cytometry; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lymphocytes; Pravastatin; Pyridines; Pyrroles

2007