pravastatin has been researched along with angiotensin ii in 14 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (21.43) | 18.2507 |
| 2000's | 7 (50.00) | 29.6817 |
| 2010's | 4 (28.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bilter, GK; Dias, J; Huang, Z; Keon, BH; Lamerdin, J; MacDonald, ML; Michnick, SW; Minami, T; Owens, S; Shang, Z; Westwick, JK; Yu, H | 1 |
| Howes, LG; Lam, W; Louis, WJ; Straznicky, NE | 1 |
| Haneda, T; Kashiwagi, Y; Kawabe, J; Kikuchi, K; Nakamura, Y; Oi, S; Osaki, J | 1 |
| Hayden, MR; Mujumdar, VS; Tyagi, SC | 1 |
| Altieri, PI; Crespo, MJ; Escobales, N; Furilla, RA | 1 |
| Fujimura, A; Sugimoto, K | 1 |
| Egashira, K; Hirouchi, Y; Inoue, S; Kitajima, S; Kitamoto, S; Kohjimoto, Y; Nakano, K; Usui, M | 1 |
| Chen, J; Mehta, JL | 1 |
| Akino, M; Matsui, Y; Okamoto, H; Onozuka, H; Tsutsui, H; Xu, Z | 1 |
| Fukumoto, Y; Rashid, M; Seto, M; Shimokawa, H; Tawara, S; Yano, K | 1 |
| Alvarez, E; González-Juanatey, JR; Rodiño-Janeiro, BK; Ucieda-Somoza, R | 1 |
| Fukumoto, Y; Kudo, S; Liao, JK; Minami, T; Nochioka, K; Shiba, N; Shimokawa, H; Takai, Y; Tanaka, S; Williams, CL | 1 |
| Aleksandrowicz, M; Drapala, A; Kozniewska, E; Sikora, M; Skrzypecki, J; Ufnal, M; Zera, T | 1 |
| Chen, Y; Dong, B; Guo, T; Li, P; Liang, WJ; Liu, C; Ma, H; Pang, XY; Shan, MR; Wang, SX; Wang, XQ; Wang, YL; Yin, YL; Yu, HY; Zhou, SN | 1 |
4 trial(s) available for pravastatin and angiotensin ii
| Article | Year |
|---|---|
Effects of pravastatin on cardiovascular reactivity to norepinephrine and angiotensin II in patients with hypercholesterolemia and systemic hypertension.
Topics: Adult; Aged; Angiotensin II; Blood Pressure; Cardiovascular System; Cholesterol; Cross-Over Studies; Double-Blind Method; Female; Humans; Hypercholesterolemia; Hypertension; Male; Middle Aged; Norepinephrine; Pravastatin; Treatment Outcome | 1995 |
Different effects of simvastatin and pravastatin on adrenal sensitivity to angiotensin II.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Cross-Over Studies; Diuretics; Female; Furosemide; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Pravastatin; Simvastatin | 2003 |
Importance of Rac1 signaling pathway inhibition in the pleiotropic effects of HMG-CoA reductase inhibitors.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adult; Angiotensin II; Animals; Atorvastatin; Cells, Cultured; Cross-Over Studies; Endothelium, Vascular; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertrophy, Left Ventricular; Leukocytes; Male; Pravastatin; Pyrroles; Quinolines; rac1 GTP-Binding Protein; ras Proteins; Rats; Rats, Inbred WKY; rho-Associated Kinases; rhoA GTP-Binding Protein; Signal Transduction | 2009 |
Statins exert the pleiotropic effects through small GTP-binding protein dissociation stimulator upregulation with a resultant Rac1 degradation.
Topics: Adaptor Proteins, Signal Transducing; Angiotensin II; Animals; Atorvastatin; Biomarkers; Cardiomegaly; Cells, Cultured; Cholesterol; Cholesterol, LDL; Coronary Vessels; Cross-Over Studies; Cytoskeletal Proteins; Disease Models, Animal; Dose-Response Relationship, Drug; Fibrosis; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Guanine Nucleotide Exchange Factors; Heptanoic Acids; Human Umbilical Vein Endothelial Cells; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Japan; Male; Mice; Mice, Knockout; Neuropeptides; Oxidative Stress; Phosphatidylinositol 3-Kinase; Pravastatin; Proto-Oncogene Proteins c-akt; Pyrroles; Quinolines; rac GTP-Binding Proteins; rac1 GTP-Binding Protein; RNA Interference; Signal Transduction; Transfection | 2013 |
10 other study(ies) available for pravastatin and angiotensin ii
| Article | Year |
|---|---|
Identifying off-target effects and hidden phenotypes of drugs in human cells.
Topics: Bacterial Proteins; Cell Line; Cell Proliferation; Cluster Analysis; Drug Design; Drug Evaluation, Preclinical; Genetics; Humans; Luminescent Proteins; Molecular Structure; Phenotype; Recombinant Fusion Proteins; Signal Transduction; Structure-Activity Relationship | 2006 |
Lovastatin prevents angiotensin II-induced cardiac hypertrophy in cultured neonatal rat heart cells.
Topics: Angiotensin II; Animals; Animals, Newborn; Calcium-Calmodulin-Dependent Protein Kinases; Cardiomegaly; Cell Division; Cell Membrane; Cells, Cultured; DNA; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Myocardium; Naphthalenes; Pravastatin; Proto-Oncogene Proteins p21(ras); Rats; Rats, Sprague-Dawley; RNA; Simvastatin | 1999 |
Homocyst(e)ine induces calcium second messenger in vascular smooth muscle cells.
Topics: Angiotensin II; Animals; Aorta; Calcium; Cells, Cultured; Collagen; Felodipine; Fluorescent Dyes; Fura-2; Glutathione; Homocysteine; Homocystine; Kinetics; Muscle, Smooth, Vascular; Neomycin; NG-Nitroarginine Methyl Ester; Pravastatin; Rats; Second Messenger Systems; Staurosporine; Tetradecanoylphorbol Acetate; Thapsigargin | 2000 |
Inhibition of smooth muscle cell calcium mobilization and aortic ring contraction by lactone vastatins.
Topics: Angiogenesis Inhibitors; Angiotensin II; Animals; Aorta, Thoracic; Calcium; Collagen Type VIII; Dose-Response Relationship, Drug; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lactones; Lovastatin; Male; Models, Cardiovascular; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Pravastatin; Rats; Rats, Sprague-Dawley; Simvastatin; Vasoconstrictor Agents | 1996 |
Cholesterol-lowering independent regression and stabilization of atherosclerotic lesions by pravastatin and by antimonocyte chemoattractant protein-1 therapy in nonhuman primates.
Topics: Angiotensin II; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticholesteremic Agents; Aorta, Abdominal; Aortic Diseases; Arteriosclerosis; Catheterization; Chemokine CCL2; Chemotaxis; Cholesterol; Cytokines; Diet, Atherogenic; DNA, Complementary; Drug Evaluation, Preclinical; Genetic Therapy; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Iliac Artery; Immunoglobulin G; Immunoglobulin M; Inflammation; Macaca fascicularis; Male; Peptidyl-Dipeptidase A; Phenotype; Pravastatin; Random Allocation; Renin; Transfection | 2004 |
Angiotensin II-mediated oxidative stress and procollagen-1 expression in cardiac fibroblasts: blockade by pravastatin and pioglitazone.
Topics: Angiotensin II; Animals; Antioxidants; Cells, Cultured; Collagen Type I; Drug Synergism; Fibroblasts; Gene Expression Regulation; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinases; Myocardium; NF-kappa B; Oxidative Stress; Pioglitazone; Pravastatin; RNA, Messenger; Superoxides; Thiazolidinediones; Tocopherols; Transcription Factor AP-1 | 2006 |
Pravastatin attenuates left ventricular remodeling and diastolic dysfunction in angiotensin II-induced hypertensive mice.
Topics: Angiotensin II; Animals; Blood Pressure; Cholesterol; Disease Models, Animal; Fibrosis; Gene Expression Regulation; Heart Failure, Diastolic; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension; Hypertrophy, Left Ventricular; Male; Mice; Mice, Inbred C57BL; Pravastatin; rho-Associated Kinases; Ventricular Remodeling | 2008 |
Pravastatin counteracts angiotensin II-induced upregulation and activation of NADPH oxidase at plasma membrane of human endothelial cells.
Topics: Angiotensin II; Cell Membrane; Cells, Cultured; Endothelium, Vascular; Enzyme Activation; Humans; NADPH Oxidases; Pravastatin; Up-Regulation | 2010 |
The effect of simvastatin and pravastatin on arterial blood pressure, baroreflex, vasoconstrictor, and hypertensive effects of angiotensin II in Sprague-Dawley rats.
Topics: Angiotensin II; Animals; Baroreflex; Blood Pressure; Drug Synergism; Heart Rate; Hypertension; Male; Pravastatin; Rats; Rats, Sprague-Dawley; Simvastatin; Vasoconstriction | 2014 |
Pravastatin activates activator protein 2 alpha to augment the angiotensin II-induced abdominal aortic aneurysms.
Topics: AMP-Activated Protein Kinases; Angiotensin II; Animals; Anticholesteremic Agents; Aortic Aneurysm, Abdominal; Apolipoproteins E; Blotting, Western; Cells, Cultured; Disease Models, Animal; Gene Expression Regulation; Humans; Male; Mice; Mice, Knockout; Myocytes, Smooth Muscle; Phosphorylation; Pravastatin; Signal Transduction; Transcription Factor AP-2 | 2017 |