pramipexole has been researched along with sulpiride in 13 studies
| Studies (pramipexole) | Trials (pramipexole) | Recent Studies (post-2010) (pramipexole) | Studies (sulpiride) | Trials (sulpiride) | Recent Studies (post-2010) (sulpiride) |
|---|---|---|---|---|---|
| 1,103 | 219 | 517 | 4,152 | 427 | 635 |
| Protein | Taxonomy | pramipexole (IC50) | sulpiride (IC50) |
|---|---|---|---|
| Carbonic anhydrase 1 | Homo sapiens (human) | 1.2 | |
| Carbonic anhydrase 2 | Homo sapiens (human) | 0.04 | |
| Alpha-2A adrenergic receptor | Homo sapiens (human) | 2.019 | |
| D(2) dopamine receptor | Homo sapiens (human) | 0.0858 | |
| D(3) dopamine receptor | Homo sapiens (human) | 0.2651 | |
| D(2) dopamine receptor | Rattus norvegicus (Norway rat) | 0.2215 | |
| Carbonic anhydrase 4 | Bos taurus (cattle) | 0.62 | |
| D(2) dopamine receptor | Canis lupus familiaris (dog) | 0.2 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (23.08) | 18.2507 |
| 2000's | 1 (7.69) | 29.6817 |
| 2010's | 7 (53.85) | 24.3611 |
| 2020's | 2 (15.38) | 2.80 |
| Authors | Studies |
|---|---|
| Alelyunas, YW; Bui, K; Empfield, JR; McCarthy, D; Pelosi-Kilby, L; Shen, C; Spreen, RC | 1 |
| Abramyan, A; Akano, EO; Aubé, J; Ferrer, M; Frankowski, KJ; Free, RB; Gandhi, D; Hu, X; Keck, TM; Moritz, AE; Shi, L; Sibley, DR; Southall, N; Steiner, J; Weiner, WS | 1 |
| Carter, AJ; Müller, RE | 1 |
| Ferrari, F; Giuliani, D; Pelloni, F | 1 |
| Kołodziejczyk, K; Maj, J; Rogóz, Z; Skuza, G | 1 |
| Bradshaw, CM; Hou, RH; Langley, RW; Samuels, ER; Szabadi, E | 1 |
| Argyropoulos, SV; Davies, SJ; Hince, DA; Hood, SD; Morris, K; Nutt, DJ; Potokar, JP; Seddon, KM | 1 |
| Marti, M; Morari, M; Viaro, R | 1 |
| Abbott, S; Barnes, A; Bullmore, ET; Craig, KJ; Ersche, KD; Merlo-Pich, EV; Müller, U; Ooi, C; Robbins, TW; Sahakian, BJ; Shabbir, SS; Suckling, J | 1 |
| Canonico, PL; Merlo, S; Sortino, MA | 1 |
| Abbott, S; Bullmore, ET; Clark, L; Craig, KJ; Ersche, KD; Fineberg, NA; Merlo-Pich, EV; Müller, U; Ooi, C; Robbins, TW; Roiser, JP; Sahakian, BJ; Shabbir, SS; Suckling, J | 1 |
| Ananthan, S; Głowacka, U; Kosmowska, B; Ossowska, K; Wardas, J | 1 |
| Fanjul, A; Fothergill, LJ; Furness, JB; Furness, SGB; Pustovit, RV; Ringuet, MT; Syder, AJ; Whitfield, EA; Wykosky, J; Yoo, EJ | 1 |
3 trial(s) available for pramipexole and sulpiride
| Article | Year |
|---|---|
Comparison of pramipexole and amisulpride on alertness, autonomic and endocrine functions in healthy volunteers.
Topics: Adult; Amisulpride; Antiparkinson Agents; Arousal; Autonomic Nervous System; Benzothiazoles; Blood Pressure; Body Temperature; Cross-Over Studies; Dopamine Agonists; Dopamine Antagonists; Double-Blind Method; Endocrine System; Heart Rate; Human Growth Hormone; Humans; Male; Pramipexole; Prolactin; Psychiatric Status Rating Scales; Pupil; Reference Values; Reflex, Pupillary; Salivation; Sulpiride; Thyrotropin | 2006 |
Dopaminergic challenges in social anxiety disorder: evidence for dopamine D3 desensitisation following successful treatment with serotonergic antidepressants.
Topics: Adult; Anxiety Disorders; Benzothiazoles; Cross-Over Studies; Diagnostic and Statistical Manual of Mental Disorders; Dopamine Agonists; Dopamine Antagonists; Double-Blind Method; Female; Humans; Male; Middle Aged; Pramipexole; Prolactin; Protein Isoforms; Receptors, Dopamine D3; Selective Serotonin Reuptake Inhibitors; Stress, Psychological; Sulpiride; Surveys and Questionnaires; Time Factors; Young Adult | 2010 |
Response perseveration in stimulant dependence is associated with striatal dysfunction and can be ameliorated by a D(2/3) receptor agonist.
Topics: Adult; Amisulpride; Amphetamine-Related Disorders; Benzothiazoles; Brain Mapping; Cocaine-Related Disorders; Compulsive Behavior; Corpus Striatum; Dopamine Agonists; Dopamine Antagonists; Female; Humans; Magnetic Resonance Imaging; Male; Obsessive-Compulsive Disorder; Pramipexole; Reversal Learning; Sulpiride | 2011 |
10 other study(ies) available for pramipexole and sulpiride
| Article | Year |
|---|---|
Experimental solubility profiling of marketed CNS drugs, exploring solubility limit of CNS discovery candidate.
Topics: Central Nervous System Agents; Drug Evaluation, Preclinical; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Solubility | 2010 |
Discovery, Optimization, and Characterization of ML417: A Novel and Highly Selective D
Topics: Animals; CHO Cells; Cricetulus; Dopamine Agonists; Dose-Response Relationship, Drug; Drug Discovery; HEK293 Cells; Hep G2 Cells; Humans; Induced Pluripotent Stem Cells; Male; Mice; Mice, Inbred C57BL; Protein Structure, Secondary; Receptors, Dopamine D3 | 2020 |
Pramipexole, a dopamine D2 autoreceptor agonist, decreases the extracellular concentration of dopamine in vivo.
Topics: 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Azepines; Benzothiazoles; Chromatography, High Pressure Liquid; Corpus Striatum; Dialysis; Dopamine; Dopamine Agents; Dopamine Antagonists; Extracellular Space; Homovanillic Acid; Male; Pramipexole; Rats; Rats, Inbred Strains; Sulpiride; Thiazoles | 1991 |
Behavioural evidence that different neurochemical mechanisms underly stretching-yawning and penile erection induced in male rats by SND 919, a new selective D2 dopamine receptor agonist.
Topics: Adrenergic alpha-Antagonists; Animals; Behavior, Animal; Benzothiazoles; Brain Chemistry; Dioxanes; Dopamine Agonists; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Idazoxan; Male; Motor Activity; Penile Erection; Phenethylamines; Pramipexole; Rats; Rats, Wistar; Receptors, Dopamine D2; Stereotyped Behavior; Sulpiride; Thiazoles; Yawning; Yohimbine | 1993 |
The behavioural effects of pramipexole, a novel dopamine receptor agonist.
Topics: Animals; Antiparkinson Agents; Benzazepines; Benzothiazoles; Body Temperature; Catalepsy; Clozapine; Dopamine Agents; Dopamine Agonists; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Interactions; Dyskinesia, Drug-Induced; Haloperidol; Injections, Subcutaneous; Levodopa; Male; Mice; Motor Activity; Pramipexole; Rats; Rats, Wistar; Receptors, Dopamine D2; Receptors, Dopamine D3; Spiperone; Stereotyped Behavior; Sulpiride; Thiazoles | 1997 |
Dual motor response to l-dopa and nociceptin/orphanin FQ receptor antagonists in 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine (MPTP) treated mice: Paradoxical inhibition is relieved by D(2)/D(3) receptor blockade.
Topics: Amisulpride; Animals; Antiparkinson Agents; Benzimidazoles; Benzothiazoles; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Drug Interactions; Drug Synergism; Levodopa; Male; Mice; Mice, Inbred C57BL; Motor Activity; Neural Inhibition; Nociceptin; Opioid Peptides; Parkinsonian Disorders; Piperidines; Pramipexole; Pyridines; Reaction Time; Receptors, Dopamine D3; Sulpiride | 2010 |
Influence of compulsivity of drug abuse on dopaminergic modulation of attentional bias in stimulant dependence.
Topics: Adult; Amisulpride; Amphetamine-Related Disorders; Attention; Benzothiazoles; Bias; Cerebellar Cortex; Cocaine-Related Disorders; Compulsive Behavior; Dopamine; Dopamine Agonists; Dopamine Antagonists; England; Female; Functional Laterality; Humans; Individuality; Magnetic Resonance Imaging; Male; Pramipexole; Prefrontal Cortex; Receptors, Dopamine; Stroop Test; Substance-Related Disorders; Sulpiride; Surveys and Questionnaires | 2010 |
Distinct effects of pramipexole on the proliferation of adult mouse sub-ventricular zone-derived cells and the appearance of a neuronal phenotype.
Topics: Animals; Benzothiazoles; Brain-Derived Neurotrophic Factor; Cell Cycle; Cell Proliferation; Cells, Cultured; Dopamine Agonists; Dopamine D2 Receptor Antagonists; Doublecortin Domain Proteins; Doublecortin Protein; Glial Fibrillary Acidic Protein; Indans; Male; Mice; Mice, Inbred Strains; Microtubule-Associated Proteins; Neurogenesis; Neurons; Neuropeptides; Pramipexole; Receptors, Dopamine D2; Receptors, Dopamine D3; Sulpiride | 2011 |
Pramipexole at a Low Dose Induces Beneficial Effect in the Harmaline-induced Model of Essential Tremor in Rats.
Topics: Amisulpride; Animals; Anti-Dyskinesia Agents; Benzothiazoles; Disease Models, Animal; Dopamine Agonists; Dopamine Antagonists; Dose-Response Relationship, Drug; Essential Tremor; Haloperidol; Harmaline; Imidazoles; Male; Movement; Nitriles; Pramipexole; Pyridines; Rats, Wistar; Receptors, Dopamine D2; Receptors, Dopamine D3; Sulpiride; Tetrahydroisoquinolines; Tetrahydronaphthalenes; Treatment Outcome | 2016 |
Dopamine and ghrelin receptor co-expression and interaction in the spinal defecation centers.
Topics: Animals; Defecation; Dopamine; Dopamine Agonists; Dopamine Antagonists; Gastrointestinal Motility; Ghrelin; Humans; Piperidines; Pramipexole; Quinazolinones; Quinpirole; Rats; Receptors, Dopamine D2; Receptors, Ghrelin; Spinal Cord; Spinal Cord Lateral Horn; Sulpiride | 2021 |