pramipexole has been researched along with sertraline in 6 studies
| Studies (pramipexole) | Trials (pramipexole) | Recent Studies (post-2010) (pramipexole) | Studies (sertraline) | Trials (sertraline) | Recent Studies (post-2010) (sertraline) |
|---|---|---|---|---|---|
| 1,103 | 219 | 517 | 3,480 | 1,028 | 1,329 |
| Protein | Taxonomy | pramipexole (IC50) | sertraline (IC50) |
|---|---|---|---|
| 5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | 1.083 | |
| Aldo-keto reductase family 1 member B1 | Rattus norvegicus (Norway rat) | 0.9848 | |
| Muscarinic acetylcholine receptor M2 | Homo sapiens (human) | 2.7675 | |
| Muscarinic acetylcholine receptor M4 | Homo sapiens (human) | 2.6309 | |
| Cytochrome P450 3A4 | Homo sapiens (human) | 0.8 | |
| Muscarinic acetylcholine receptor M5 | Homo sapiens (human) | 0.5073 | |
| Alpha-2A adrenergic receptor | Homo sapiens (human) | 0.2888 | |
| Cytochrome P450 2D6 | Homo sapiens (human) | 1.4 | |
| Muscarinic acetylcholine receptor M1 | Homo sapiens (human) | 1.2882 | |
| Angiotensin-converting enzyme | Oryctolagus cuniculus (rabbit) | 8.3173 | |
| Alpha-2B adrenergic receptor | Homo sapiens (human) | 0.1814 | |
| Alpha-2C adrenergic receptor | Homo sapiens (human) | 4.477 | |
| D | Rattus norvegicus (Norway rat) | 0.26 | |
| D(3) dopamine receptor | Rattus norvegicus (Norway rat) | 0.26 | |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | 0.8783 | |
| Sodium-dependent dopamine transporter | Rattus norvegicus (Norway rat) | 0.825 | |
| D(1B) dopamine receptor | Rattus norvegicus (Norway rat) | 0.26 | |
| 5-hydroxytryptamine receptor 2A | Homo sapiens (human) | 2.7409 | |
| 5-hydroxytryptamine receptor 2C | Homo sapiens (human) | 1.083 | |
| D(4) dopamine receptor | Rattus norvegicus (Norway rat) | 0.26 | |
| 3-oxo-5-alpha-steroid 4-dehydrogenase 2 | Homo sapiens (human) | 0.8 | |
| Sodium-dependent serotonin transporter | Homo sapiens (human) | 0.0016 | |
| Sodium-dependent serotonin transporter | Rattus norvegicus (Norway rat) | 0.1743 | |
| Melanocortin receptor 5 | Homo sapiens (human) | 4.598 | |
| Cytochrome P450 2C19 | Homo sapiens (human) | 0.655 | |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | 3.3935 | |
| D(2) dopamine receptor | Rattus norvegicus (Norway rat) | 0.26 | |
| Sodium-dependent dopamine transporter | Homo sapiens (human) | 0.2175 | |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | 8.3173 | |
| Nuclear receptor subfamily 3 group C member 3 | Bos taurus (cattle) | 8.3173 | |
| Sigma non-opioid intracellular receptor 1 | Homo sapiens (human) | 0.0697 | |
| Transporter | Rattus norvegicus (Norway rat) | 0.26 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (50.00) | 29.6817 |
| 2010's | 3 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Alelyunas, YW; Bui, K; Empfield, JR; McCarthy, D; Pelosi-Kilby, L; Shen, C; Spreen, RC | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Breen, JA; DeBattista, C; Schatzberg, AF; Solvason, HB | 1 |
| Antonini, A; Barone, P; Bracco, F; Marconi, R; Morgante, L; Musch, B; Scarzella, L; Zappia, M | 1 |
| Antonini, A | 1 |
| Barone, P | 1 |
2 review(s) available for pramipexole and sertraline
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Treatment of depressive symptoms in Parkinson's disease.
Topics: Antidepressive Agents, Tricyclic; Antiparkinson Agents; Benzothiazoles; Depression; Desipramine; Dopamine Agonists; Humans; Levodopa; Nortriptyline; Parkinson Disease; Pramipexole; Randomized Controlled Trials as Topic; Selective Serotonin Reuptake Inhibitors; Sertraline | 2011 |
1 trial(s) available for pramipexole and sertraline
| Article | Year |
|---|---|
Pramipexole versus sertraline in the treatment of depression in Parkinson's disease: a national multicenter parallel-group randomized study.
Topics: Aged; Analysis of Variance; Antidepressive Agents; Antiparkinson Agents; Benzothiazoles; Depressive Disorder, Major; Female; Humans; Male; Middle Aged; Parkinson Disease; Pramipexole; Psychiatric Status Rating Scales; Sertraline; Single-Blind Method | 2006 |
3 other study(ies) available for pramipexole and sertraline
| Article | Year |
|---|---|
Experimental solubility profiling of marketed CNS drugs, exploring solubility limit of CNS discovery candidate.
Topics: Central Nervous System Agents; Drug Evaluation, Preclinical; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Solubility | 2010 |
Pramipexole augmentation of a selective serotonin reuptake inhibitor in the treatment of depression.
Topics: Benzothiazoles; Chronic Disease; Depressive Disorder, Major; Dopamine Agonists; Drug Therapy, Combination; Female; Humans; Middle Aged; Pramipexole; Selective Serotonin Reuptake Inhibitors; Sertraline; Thiazoles | 2000 |
Unraveling depression in Parkinson's disease.
Topics: Antidepressive Agents; Benzothiazoles; Clinical Trials as Topic; Cohort Studies; Depression; Depressive Disorder; Dopamine; Dopamine Agonists; Drug Interactions; Humans; Multicenter Studies as Topic; Parkinson Disease; Pramipexole; Quality of Life; Serotonin; Sertraline | 2008 |