pramipexole has been researched along with riluzole in 6 studies
| Studies (pramipexole) | Trials (pramipexole) | Recent Studies (post-2010) (pramipexole) | Studies (riluzole) | Trials (riluzole) | Recent Studies (post-2010) (riluzole) |
|---|---|---|---|---|---|
| 1,103 | 219 | 517 | 1,244 | 153 | 572 |
| Protein | Taxonomy | pramipexole (IC50) | riluzole (IC50) |
|---|---|---|---|
| Sodium channel protein type 2 subunit alpha | Rattus norvegicus (Norway rat) | 4.73 | |
| Cytochrome P450 1A2 | Homo sapiens (human) | 10 | |
| Aldo-keto reductase family 1 member B1 | Rattus norvegicus (Norway rat) | 1.733 | |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | 1.733 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 4 (66.67) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Alelyunas, YW; Bui, K; Empfield, JR; McCarthy, D; Pelosi-Kilby, L; Shen, C; Spreen, RC | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Bloch, DA; Ciraulo, AM; Ciraulo, DA; Elkashef, A; Knapp, CM; Leiderman, DB; LoCastro, J; Montgomery, MA; Sarid-Segal, O | 1 |
| Amburgey, C; Archibald, D; Bozik, ME; Cudkowicz, M; Gribkoff, VK; Ingersoll, EW; Mather, JL; Miller, R; Mitsumoto, H; Moore, DH; Moritz, J; Schoenfeld, D; Shefner, J; Sullivan, M | 1 |
| Desaphy, JF; Lentini, G; Majoral, JP; Mignani, S | 1 |
2 review(s) available for pramipexole and riluzole
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
From Riluzole to Dexpramipexole via Substituted-Benzothiazole Derivatives for Amyotrophic Lateral Sclerosis Disease Treatment: Case Studies.
Topics: Amyotrophic Lateral Sclerosis; Animals; Benzothiazoles; Clinical Trials as Topic; Drug Approval; Drug Evaluation, Preclinical; Humans; Neuroprotective Agents; Pramipexole; Riluzole; Small Molecule Libraries; Toluene; Treatment Outcome | 2020 |
2 trial(s) available for pramipexole and riluzole
| Article | Year |
|---|---|
Efficacy screening trials of paroxetine, pentoxifylline, riluzole, pramipexole and venlafaxine in cocaine dependence.
Topics: Adolescent; Adult; Antidepressive Agents; Benzothiazoles; Cocaine-Related Disorders; Cyclohexanols; Dopamine Agonists; Double-Blind Method; Female; Humans; Male; Middle Aged; Neuroprotective Agents; Paroxetine; Pentoxifylline; Phosphodiesterase Inhibitors; Pramipexole; Riluzole; Selective Serotonin Reuptake Inhibitors; Thiazoles; Venlafaxine Hydrochloride | 2005 |
The effects of dexpramipexole (KNS-760704) in individuals with amyotrophic lateral sclerosis.
Topics: Aged; Amyotrophic Lateral Sclerosis; Benzothiazoles; Double-Blind Method; Female; Humans; Male; Middle Aged; Mitochondria; Muscle Strength; Muscles; Pramipexole; Riluzole; Single-Blind Method | 2011 |
2 other study(ies) available for pramipexole and riluzole
| Article | Year |
|---|---|
Experimental solubility profiling of marketed CNS drugs, exploring solubility limit of CNS discovery candidate.
Topics: Central Nervous System Agents; Drug Evaluation, Preclinical; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Solubility | 2010 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |