Page last updated: 2024-09-03

pramipexole and rasagiline

pramipexole has been researched along with rasagiline in 15 studies

Compound Research Comparison

Studies
(pramipexole)
Trials
(pramipexole)
Recent Studies (post-2010)
(pramipexole)
Studies
(rasagiline)
Trials
(rasagiline)
Recent Studies (post-2010) (rasagiline)
1,10321951753572314

Protein Interaction Comparison

ProteinTaxonomypramipexole (IC50)rasagiline (IC50)
CholinesteraseHomo sapiens (human)2.3865
Amine oxidase [flavin-containing] BRattus norvegicus (Norway rat)1.0029
Amine oxidase [flavin-containing] A Rattus norvegicus (Norway rat)0.2115
Amine oxidase [flavin-containing] AHomo sapiens (human)1.088
AcetylcholinesteraseHomo sapiens (human)0.019
Amine oxidase [flavin-containing] BHomo sapiens (human)0.2217

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (20.00)29.6817
2010's10 (66.67)24.3611
2020's2 (13.33)2.80

Authors

AuthorsStudies
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Goetz, CG; Poewe, W; Rascol, O; Sampaio, C1
Schapira, AH1
Armand, C; Cochran, J; François, C; Haycox, A; Murteira, S1
Bozi, M; Christodoulou, C; Douzenis, A; Gasparinatos, G; Stamboulis, E; Stefanis, C; Stefanis, L; Stefanis, N1
Janszky, J; Kovacs, N; Nagy, F1
Arami, MA; Ayromlou, H; Najmi, S1
Tarrants, ML; Zagmutt, FJ1
Blin, O; Lancrenon, S; Pitel, S; Viallet, F1
Sheehan, J; Thorpe, M; Wilson, L1
Agúndez, JA; Alonso-Navarro, H; García-Martín, E; Jiménez-Jiménez, FJ1
Elmer, L; Friedman, H; Giladi, N; Hauser, RA; Kadosh, S; Kieburtz, K; Klepiskaya, OS; Kreitzman, DL; Leinonen, M; Lew, MF; Linvah, N; Litman, P; Olanow, CW; Russell, DS; The P B Study Group, F1
Challet-Bouju, G; Derkinderen, P; Fève, JM; Grall-Bronnec, M; Le Moigne, M; Leboucher, J; Victorri-Vigneau, C1
Kalaria, D; Kalia, YN; Serna, C; Singhal, M1
Brotchie, J; Friedman, H; Giladi, N; Hauser, RA; Litman, P; Oren, S; Poewe, W1

Reviews

6 review(s) available for pramipexole and rasagiline

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Evidence-based medical review update: pharmacological and surgical treatments of Parkinson's disease: 2001 to 2004.
    Movement disorders : official journal of the Movement Disorder Society, 2005, Volume: 20, Issue:5

    Topics: Amantadine; Antiparkinson Agents; Apomorphine; Benzophenones; Benzothiazoles; Bromocriptine; Cabergoline; Catechol O-Methyltransferase Inhibitors; Deep Brain Stimulation; Dihydroergocryptine; Ergolines; Fetal Tissue Transplantation; Globus Pallidus; Humans; Indans; Indoles; Levodopa; Lisuride; Mesencephalon; Monoamine Oxidase Inhibitors; Neurosurgical Procedures; Nitrophenols; Parkinson Disease; Pergolide; Piribedil; Pramipexole; Selegiline; Thiazoles; Tolcapone

2005
Present and future drug treatment for Parkinson's disease.
    Journal of neurology, neurosurgery, and psychiatry, 2005, Volume: 76, Issue:11

    Topics: Benzothiazoles; Corpus Striatum; Disease Progression; Dopamine Agonists; Drug Therapy, Combination; Humans; Indans; Indoles; Levodopa; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Parkinson Disease; Pramipexole; Psychomotor Performance; Sexual Dysfunction, Physiological; Sleep Wake Disorders; Substantia Nigra; Thiazoles; Urinary Incontinence

2005
Indirect comparisons of adverse events and dropout rates in early Parkinson's disease trials of pramipexole, ropinirole, and rasagiline.
    The International journal of neuroscience, 2012, Volume: 122, Issue:7

    Topics: Antiparkinson Agents; Benzothiazoles; Cognition Disorders; Cross-Sectional Studies; Databases, Bibliographic; Fatigue; Female; Gastrointestinal Diseases; Humans; Indans; Indoles; Logistic Models; Male; Parkinson Disease; Patient Dropouts; Pramipexole; Sleep Wake Disorders; Treatment Outcome

2012
Anti-Parkinson's disease drugs and pharmacogenetic considerations.
    Expert opinion on drug metabolism & toxicology, 2013, Volume: 9, Issue:7

    Topics: Aryl Hydrocarbon Hydroxylases; Benzothiazoles; Benztropine; Bromocriptine; Cabergoline; Catechols; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 CYP2B6; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP3A; Ergolines; Genetic Markers; Humans; Indans; Indoles; Levodopa; Lisuride; Nitriles; Parkinson Disease; Pergolide; Pharmacogenetics; Pramipexole; Receptors, Dopamine D2; Receptors, Dopamine D3; Reproducibility of Results; Selegiline

2013
P2B001 (Extended Release Pramipexole and Rasagiline): A New Treatment Option in Development for Parkinson's Disease.
    Advances in therapy, 2022, Volume: 39, Issue:5

    Topics: Humans; Indans; Levodopa; Parkinson Disease; Pramipexole

2022

Trials

2 trial(s) available for pramipexole and rasagiline

ArticleYear
Evaluation of the safety and tolerability of rasagiline in the treatment of the early stages of Parkinson's disease.
    Current medical research and opinion, 2013, Volume: 29, Issue:1

    Topics: Aged; Antiparkinson Agents; Benzothiazoles; Double-Blind Method; Female; Gastrointestinal Diseases; Humans; Indans; Male; Middle Aged; Monoamine Oxidase Inhibitors; Parkinson Disease; Pramipexole; Sleep Wake Disorders; Time Factors

2013
A randomized trial of a low-dose Rasagiline and Pramipexole combination (P2B001) in early Parkinson's disease.
    Movement disorders : official journal of the Movement Disorder Society, 2017, Volume: 32, Issue:5

    Topics: Aged; Antiparkinson Agents; Benzothiazoles; Delayed-Action Preparations; Double-Blind Method; Drug Combinations; Female; Humans; Indans; Israel; Male; Middle Aged; Neuroprotective Agents; Parkinson Disease; Pramipexole; Severity of Illness Index; Triethylenemelamine; United States

2017

Other Studies

7 other study(ies) available for pramipexole and rasagiline

ArticleYear
Cost effectiveness of rasagiline and pramipexole as treatment strategies in early Parkinson's disease in the UK setting: an economic Markov model evaluation.
    Drugs & aging, 2009, Volume: 26, Issue:9

    Topics: Aged; Antiparkinson Agents; Benzothiazoles; Clinical Trials as Topic; Cost-Benefit Analysis; Disease Progression; Dopamine Agonists; Female; Health Care Costs; Humans; Indans; Insurance, Health, Reimbursement; Male; Markov Chains; Middle Aged; Models, Economic; Monoamine Oxidase Inhibitors; Monte Carlo Method; Parkinson Disease; Pramipexole; Probability; Quality-Adjusted Life Years; State Medicine; Treatment Outcome; United Kingdom

2009
Isolated delusional syndrome in Parkinson's Disease.
    Parkinsonism & related disorders, 2010, Volume: 16, Issue:8

    Topics: Aged; Amantadine; Antiparkinson Agents; Benserazide; Benzothiazoles; Catechols; Clonazepam; Female; Humans; Indans; Indoles; Levodopa; Male; Middle Aged; Nitriles; Parkinson Disease; Pramipexole; Schizophrenia, Paranoid; Syndrome

2010
Cost effectiveness of rasagiline and pramipexole as treatment strategies in early Parkinson's disease in the UK setting: An economic Markov model evaluation.
    Drugs & aging, 2011, Feb-01, Volume: 28, Issue:2

    Topics: Aged; Antiparkinson Agents; Benzothiazoles; Cost-Benefit Analysis; Dopamine Agonists; Humans; Indans; Markov Chains; Models, Economic; Monoamine Oxidase Inhibitors; Parkinson Disease; Pramipexole; United Kingdom

2011
Hemiparkinsonism-hemiatrophy syndrome.
    Archives of Iranian medicine, 2011, Volume: 14, Issue:2

    Topics: Adult; Antiparkinson Agents; Atrophy; Benzothiazoles; Biperiden; Carbidopa; Cerebral Cortex; Cerebral Ventricles; Dopamine Agonists; Drug Combinations; Humans; Indans; Levodopa; Magnetic Resonance Imaging; Male; Monoamine Oxidase Inhibitors; Parkinson Disease, Secondary; Pramipexole; Tomography, X-Ray Computed

2011
Three cases of impulse control disorder in Parkinson's disease patients receiving dopamine replacement therapy.
    Irish medical journal, 2013, Volume: 106, Issue:1

    Topics: Adult; Amantadine; Antiparkinson Agents; Benzothiazoles; Carbidopa; Catechols; Disruptive, Impulse Control, and Conduct Disorders; Drug Combinations; Female; Humans; Indans; Indoles; Levodopa; Male; Middle Aged; Neuroprotective Agents; Parkinson Disease; Pramipexole; Selegiline

2013
Hair-pulling disorder complicated by skin-picking disorder: An unknown side-effect of dopamine replacement therapy?
    Psychiatry and clinical neurosciences, 2018, Volume: 72, Issue:10

    Topics: Benzothiazoles; Dopamine Agonists; Drug Therapy, Combination; Female; Humans; Indans; Indoles; Middle Aged; Monoamine Oxidase Inhibitors; Pramipexole; Self-Injurious Behavior; Trichotillomania

2018
Effect of continuous and multi-phasic current profiles on the iontophoretic transport of pramipexole, rasagiline and huperzine A: Depicting temporal variation and biodistribution in the skin.
    International journal of pharmaceutics, 2021, Apr-15, Volume: 599

    Topics: Administration, Cutaneous; Alkaloids; Indans; Iontophoresis; Pramipexole; Sesquiterpenes; Skin; Tissue Distribution

2021