Page last updated: 2024-09-03

pramipexole and promethazine

pramipexole has been researched along with promethazine in 2 studies

Compound Research Comparison

Studies
(pramipexole)
Trials
(pramipexole)
Recent Studies (post-2010)
(pramipexole)
Studies
(promethazine)
Trials
(promethazine)
Recent Studies (post-2010) (promethazine)
1,1032195173,110299235

Protein Interaction Comparison

ProteinTaxonomypramipexole (IC50)promethazine (IC50)
Spike glycoproteinBetacoronavirus England 15.86
Replicase polyprotein 1abBetacoronavirus England 15.86
Transmembrane protease serine 2Homo sapiens (human)5.86
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)0.012
Procathepsin LHomo sapiens (human)5.86
Aldo-keto reductase family 1 member B1Rattus norvegicus (Norway rat)4.238
Muscarinic acetylcholine receptor M2Homo sapiens (human)0.035
Muscarinic acetylcholine receptor M4Homo sapiens (human)0.0076
Muscarinic acetylcholine receptor M5Homo sapiens (human)0.0046
Alpha-2A adrenergic receptorHomo sapiens (human)0.681
Replicase polyprotein 1aSevere acute respiratory syndrome-related coronavirus5.86
Replicase polyprotein 1abHuman coronavirus 229E5.86
Replicase polyprotein 1abSevere acute respiratory syndrome-related coronavirus5.86
Replicase polyprotein 1abSevere acute respiratory syndrome coronavirus 25.86
Muscarinic acetylcholine receptor M1Homo sapiens (human)0.014
D(2) dopamine receptorHomo sapiens (human)0.4395
Alpha-2B adrenergic receptorHomo sapiens (human)0.053
Alpha-2C adrenergic receptorHomo sapiens (human)2.431
5-hydroxytryptamine receptor 1ARattus norvegicus (Norway rat)2.596
Muscarinic acetylcholine receptor M3Homo sapiens (human)0.02
D(1A) dopamine receptorHomo sapiens (human)2.744
Sodium-dependent noradrenaline transporter Homo sapiens (human)4.238
Histamine H2 receptorHomo sapiens (human)1.165
Alpha-1D adrenergic receptorHomo sapiens (human)0.183
5-hydroxytryptamine receptor 2AHomo sapiens (human)0.045
5-hydroxytryptamine receptor 2CHomo sapiens (human)0.012
5-hydroxytryptamine receptor 1BRattus norvegicus (Norway rat)2.596
Sodium-dependent serotonin transporterHomo sapiens (human)5.8
Histamine H1 receptorHomo sapiens (human)0.0041
D(3) dopamine receptorHomo sapiens (human)0.559
5-hydroxytryptamine receptor 2BHomo sapiens (human)0.068
5-hydroxytryptamine receptor 6Homo sapiens (human)2.429
Spike glycoproteinSevere acute respiratory syndrome-related coronavirus5.86
Sigma non-opioid intracellular receptor 1Homo sapiens (human)0.287
Angiotensin-converting enzyme 2 Homo sapiens (human)5.86

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1

Reviews

1 review(s) available for pramipexole and promethazine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

1 other study(ies) available for pramipexole and promethazine

ArticleYear
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013