Compounds > pramipexole
Page last updated: 2024-09-03

pramipexole and prochlorperazine

pramipexole has been researched along with prochlorperazine in 2 studies

Compound Research Comparison

Studies
(pramipexole)		Trials
(pramipexole)		Recent Studies (post-2010)
(pramipexole)		Studies
(prochlorperazine)		Trials
(prochlorperazine)		Recent Studies (post-2010) (prochlorperazine)
1,1032195171,125206110

Protein Interaction Comparison

ProteinTaxonomypramipexole (IC50)prochlorperazine (IC50)
Mcl-1Homo sapiens (human)3.7733
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)0.078
Bile salt export pumpHomo sapiens (human)10
Cytochrome P450 1A2Homo sapiens (human)2
Tyrosine-protein kinase FynHomo sapiens (human)5.684
Aldo-keto reductase family 1 member B1Rattus norvegicus (Norway rat)0.4
Muscarinic acetylcholine receptor M2Homo sapiens (human)3.112
Muscarinic acetylcholine receptor M4Homo sapiens (human)1.363
Muscarinic acetylcholine receptor M5Homo sapiens (human)0.22
Alpha-2A adrenergic receptorHomo sapiens (human)0.169
Cytochrome P450 2D6Homo sapiens (human)0.3
Muscarinic acetylcholine receptor M1Homo sapiens (human)1.013
Angiotensin-converting enzymeOryctolagus cuniculus (rabbit)1.8481
D(2) dopamine receptorHomo sapiens (human)0.011
Alpha-2B adrenergic receptorHomo sapiens (human)0.01
Alpha-2C adrenergic receptorHomo sapiens (human)0.082
5-hydroxytryptamine receptor 1ARattus norvegicus (Norway rat)0.95
Muscarinic acetylcholine receptor M3Homo sapiens (human)1.514
D(1A) dopamine receptorHomo sapiens (human)0.155
D(4) dopamine receptorHomo sapiens (human)2.311
Sodium-dependent noradrenaline transporter Homo sapiens (human)0.4
Alpha-1D adrenergic receptorHomo sapiens (human)0.034
5-hydroxytryptamine receptor 2AHomo sapiens (human)0.0071
5-hydroxytryptamine receptor 2CHomo sapiens (human)0.078
5-hydroxytryptamine receptor 1BRattus norvegicus (Norway rat)0.95
Sodium-dependent serotonin transporterHomo sapiens (human)1.169
Pleiotropic ABC efflux transporter of multiple drugsSaccharomyces cerevisiae S288C1.7
Histamine H1 receptorHomo sapiens (human)0.024
D(3) dopamine receptorHomo sapiens (human)0.013
5-hydroxytryptamine receptor 2BHomo sapiens (human)0.102
5-hydroxytryptamine receptor 6Homo sapiens (human)0.267
Sodium-dependent dopamine transporter Homo sapiens (human)1.735
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)1.8481
Nuclear receptor subfamily 3 group C member 3 Bos taurus (cattle)1.8481
Sigma non-opioid intracellular receptor 1Homo sapiens (human)0.054

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1

Reviews

1 review(s) available for pramipexole and prochlorperazine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

1 other study(ies) available for pramipexole and prochlorperazine

ArticleYear
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013