Page last updated: 2024-09-03

pramipexole and nimodipine

pramipexole has been researched along with nimodipine in 3 studies

Compound Research Comparison

Studies
(pramipexole)
Trials
(pramipexole)
Recent Studies (post-2010)
(pramipexole)
Studies
(nimodipine)
Trials
(nimodipine)
Recent Studies (post-2010) (nimodipine)
1,1032195172,936317597

Protein Interaction Comparison

ProteinTaxonomypramipexole (IC50)nimodipine (IC50)
Voltage-dependent L-type calcium channel subunit alpha-1CCavia porcellus (domestic guinea pig)0.11
Cytochrome P450 2C9 Homo sapiens (human)2.19
Cannabinoid receptor 1Homo sapiens (human)1.736
Cytochrome P450 2C19Homo sapiens (human)4
Cytochrome P450 2J2Homo sapiens (human)3.38
Voltage-dependent calcium channel subunit alpha-2/delta-1Homo sapiens (human)0.0298
Voltage-dependent L-type calcium channel subunit beta-2Homo sapiens (human)0.0298
cAMP-specific 3',5'-cyclic phosphodiesterase 4DHomo sapiens (human)7.15
Voltage-dependent L-type calcium channel subunit alpha-1CHomo sapiens (human)0.0699
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1CHomo sapiens (human)1.243
Bile acid receptorHomo sapiens (human)8.96

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's2 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Andricopulo, AD; Moda, TL; Montanari, CA1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1

Reviews

1 review(s) available for pramipexole and nimodipine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

2 other study(ies) available for pramipexole and nimodipine

ArticleYear
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013