Page last updated: 2024-09-03

pramipexole and morphine

pramipexole has been researched along with morphine in 6 studies

Compound Research Comparison

Studies
(pramipexole)
Trials
(pramipexole)
Recent Studies (post-2010)
(pramipexole)
Studies
(morphine)
Trials
(morphine)
Recent Studies (post-2010) (morphine)
1,10321951744,2705,2008,695

Protein Interaction Comparison

ProteinTaxonomypramipexole (IC50)morphine (IC50)
Delta-type opioid receptorMus musculus (house mouse)0.2939
Delta-type opioid receptorRattus norvegicus (Norway rat)0.2278
Kappa-type opioid receptorMus musculus (house mouse)0.0828
Mu-type opioid receptorRattus norvegicus (Norway rat)0.0385
Kappa-type opioid receptorRattus norvegicus (Norway rat)0.0545
Mu-type opioid receptorHomo sapiens (human)0.122
Delta-type opioid receptorHomo sapiens (human)0.1199
Kappa-type opioid receptorCavia porcellus (domestic guinea pig)0.9308
Kappa-type opioid receptorHomo sapiens (human)0.655
Mu-type opioid receptorMus musculus (house mouse)0.3305
Mu-type opioid receptorCavia porcellus (domestic guinea pig)0.202
Beta-2 adrenergic receptorCavia porcellus (domestic guinea pig)0.25

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (16.67)29.6817
2010's3 (50.00)24.3611
2020's2 (33.33)2.80

Authors

AuthorsStudies
Andricopulo, AD; Moda, TL; Montanari, CA1
Alelyunas, YW; Bui, K; Empfield, JR; McCarthy, D; Pelosi-Kilby, L; Shen, C; Spreen, RC1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Kokare, DM; Nakhate, KT; Singh, U; Singru, PS; Subhedar, NK; Upadhya, MA1
Brewer, KL; Clemens, S; Dinkins, ML; Lim, SA; Patton, R; Rodgers, HM; Yow, J1
Clemens, S; de Castro BrĂ¡s, LE; Dinkins, ML; Gaweda, G; Grilo, GA; Iyer, RP; Shaver, PR; Stoffel, HJ1

Reviews

1 review(s) available for pramipexole and morphine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

5 other study(ies) available for pramipexole and morphine

ArticleYear
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
Experimental solubility profiling of marketed CNS drugs, exploring solubility limit of CNS discovery candidate.
    Bioorganic & medicinal chemistry letters, 2010, Dec-15, Volume: 20, Issue:24

    Topics: Central Nervous System Agents; Drug Evaluation, Preclinical; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Solubility

2010
CART peptide in the nucleus accumbens shell acts downstream to dopamine and mediates the reward and reinforcement actions of morphine.
    Neuropharmacology, 2012, Volume: 62, Issue:4

    Topics: Animals; Benzothiazoles; Dopamine; Dopamine Agonists; Male; Morphine; Narcotics; Nerve Tissue Proteins; Neurons; Nucleus Accumbens; Pramipexole; Rats; Rats, Sprague-Dawley; Reward; Self Administration; Signal Transduction

2012
Dopamine D
    Pharmacology, biochemistry, and behavior, 2020, Volume: 194

    Topics: Analgesia; Analgesics, Opioid; Animals; Chronic Pain; Dopamine Agonists; Dopamine Antagonists; Drug Combinations; Drug Tolerance; Female; Male; Mice; Mice, Inbred C57BL; Morphine; Neuralgia; Pramipexole; Rats; Rats, Long-Evans; Receptors, Dopamine D1; Receptors, Dopamine D3; Substance Withdrawal Syndrome

2020
Dopamine receptor D3 agonist (Pramipexole) reduces morphine-induced cardiac fibrosis.
    Biochemical and biophysical research communications, 2020, 09-03, Volume: 529, Issue:4

    Topics: Animals; Collagen; Fibrosis; Hypertrophy; Male; Mice, Inbred C57BL; Morphine; Myocardium; Myocytes, Cardiac; Pramipexole; Receptors, Dopamine D3; Systole

2020