Page last updated: 2024-09-03

pramipexole and mirtazapine

pramipexole has been researched along with mirtazapine in 6 studies

Compound Research Comparison

Studies (pramipexole)	Trials (pramipexole)	Recent Studies (post-2010) (pramipexole)	Studies (mirtazapine)	Trials (mirtazapine)	Recent Studies (post-2010) (mirtazapine)
1,103	219	517	1,538	324	646

Protein Interaction Comparison

Protein	Taxonomy	mirtazapine (IC50)
Alpha-2A adrenergic receptor	Homo sapiens (human)	0.0851
Alpha-1B adrenergic receptor	Rattus norvegicus (Norway rat)	0.2239
Alpha-2B adrenergic receptor	Homo sapiens (human)	0.2239
Alpha-2C adrenergic receptor	Homo sapiens (human)	0.1995
Alpha-1D adrenergic receptor	Rattus norvegicus (Norway rat)	0.2239
Alpha-1A adrenergic receptor	Homo sapiens (human)	3.1623
Alpha-1A adrenergic receptor	Rattus norvegicus (Norway rat)	0.2239
Transporter	Rattus norvegicus (Norway rat)	0.26

Research

Studies (6)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	6 (100.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Alelyunas, YW; Bui, K; Empfield, JR; McCarthy, D; Pelosi-Kilby, L; Shen, C; Spreen, RC	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Davis, JM; Torrey, EF	1
Kato, S; Makiguchi, A; Nishida, M; Nisijima, K; Shioda, K; Suda, S	1
Grasso, SA; Holtz, NA; Napier, TC; Persons, AL; Tedford, SE	1

Reviews

2 review(s) available for pramipexole and mirtazapine

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Adjunct treatments for schizophrenia and bipolar disorder: what to try when you are out of ideas. Clinical schizophrenia & related psychoses, 2012, Volume: 5, Issue:4 Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Aspirin; Benzothiazoles; Bipolar Disorder; Celecoxib; Chemotherapy, Adjuvant; Cyclooxygenase 2 Inhibitors; Dopamine Agonists; Estrogens; Fatty Acids, Omega-3; Folic Acid; Humans; Mianserin; Minocycline; Mirtazapine; Pramipexole; Pregnenolone; Pyrazoles; Randomized Controlled Trials as Topic; Schizophrenia; Sulfonamides; Treatment Outcome; Vitamin B Complex	2012

Article

Year

DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.

Drug discovery today, 2016, Volume: 21, Issue:4

Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Adjunct treatments for schizophrenia and bipolar disorder: what to try when you are out of ideas.

Clinical schizophrenia & related psychoses, 2012, Volume: 5, Issue:4

Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Aspirin; Benzothiazoles; Bipolar Disorder; Celecoxib; Chemotherapy, Adjuvant; Cyclooxygenase 2 Inhibitors; Dopamine Agonists; Estrogens; Fatty Acids, Omega-3; Folic Acid; Humans; Mianserin; Minocycline; Mirtazapine; Pramipexole; Pregnenolone; Pyrazoles; Randomized Controlled Trials as Topic; Schizophrenia; Sulfonamides; Treatment Outcome; Vitamin B Complex

2012

Other Studies

4 other study(ies) available for pramipexole and mirtazapine

Article	Year
Experimental solubility profiling of marketed CNS drugs, exploring solubility limit of CNS discovery candidate. Bioorganic & medicinal chemistry letters, 2010, Dec-15, Volume: 20, Issue:24 Topics: Central Nervous System Agents; Drug Evaluation, Preclinical; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Solubility	2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Mirtazapine-induced restless legs syndrome treated with pramipexole. The Journal of neuropsychiatry and clinical neurosciences, 2015,Winter, Volume: 27, Issue:1 Topics: Aged, 80 and over; Antidepressive Agents, Tricyclic; Antiparkinson Agents; Benzothiazoles; Female; Humans; Mianserin; Mirtazapine; Pramipexole; Restless Legs Syndrome	2015
Pharmacologically distinct pramipexole-mediated akinesia vs. risk-taking in a rat model of Parkinson's disease. Progress in neuro-psychopharmacology & biological psychiatry, 2016, 10-03, Volume: 70 Topics: Animals; Antidepressive Agents, Tricyclic; Antiparkinson Agents; Benzothiazoles; Corpus Striatum; Delay Discounting; Dopamine Agonists; Dose-Response Relationship, Drug; Impulsive Behavior; Male; Mianserin; Mirtazapine; Motor Activity; Oxidopamine; Parkinsonian Disorders; Pramipexole; Random Allocation; Rats, Sprague-Dawley; Risk-Taking; Self Stimulation	2016