Compounds > pramipexole
Page last updated: 2024-09-03

pramipexole and idazoxan

pramipexole has been researched along with idazoxan in 4 studies

Compound Research Comparison

Studies
(pramipexole)		Trials
(pramipexole)		Recent Studies (post-2010)
(pramipexole)		Studies
(idazoxan)		Trials
(idazoxan)		Recent Studies (post-2010) (idazoxan)
1,1032195171,49940123

Protein Interaction Comparison

ProteinTaxonomypramipexole (IC50)idazoxan (IC50)
Alpha-2A adrenergic receptorHomo sapiens (human)0.0083
Alpha-1B adrenergic receptorRattus norvegicus (Norway rat)0.0195
Alpha-2B adrenergic receptorHomo sapiens (human)0.0195
Alpha-2C adrenergic receptorHomo sapiens (human)0.0537
Alpha-1D adrenergic receptorRattus norvegicus (Norway rat)0.0195
Alpha-1A adrenergic receptorHomo sapiens (human)2.884
Alpha-1A adrenergic receptorRattus norvegicus (Norway rat)0.0195

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (50.00)18.2507
2000's1 (25.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Ferrari, F; Giuliani, D; Pelloni, F1
Ferrari, F; Giuliani, D1
Blier, P; Chernoloz, O; El Mansari, M1

Other Studies

4 other study(ies) available for pramipexole and idazoxan

ArticleYear
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Behavioural evidence that different neurochemical mechanisms underly stretching-yawning and penile erection induced in male rats by SND 919, a new selective D2 dopamine receptor agonist.
    Psychopharmacology, 1993, Volume: 113, Issue:2

    Topics: Adrenergic alpha-Antagonists; Animals; Behavior, Animal; Benzothiazoles; Brain Chemistry; Dioxanes; Dopamine Agonists; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Idazoxan; Male; Motor Activity; Penile Erection; Phenethylamines; Pramipexole; Rats; Rats, Wistar; Receptors, Dopamine D2; Stereotyped Behavior; Sulpiride; Thiazoles; Yawning; Yohimbine

1993
Influence of idazoxan on the dopamine D2 receptor agonist-induced behavioural effects in rats.
    European journal of pharmacology, 1993, Nov-30, Volume: 250, Issue:1

    Topics: Adrenergic alpha-Antagonists; Animals; Azepines; Behavior, Animal; Benzothiazoles; Dioxanes; Dopamine Agents; Dose-Response Relationship, Drug; Idazoxan; Lisuride; Male; Pramipexole; Rats; Rats, Wistar; Receptors, Dopamine D2; Stereotyped Behavior; Thiazoles

1993
Sustained administration of pramipexole modifies the spontaneous firing of dopamine, norepinephrine, and serotonin neurons in the rat brain.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2009, Volume: 34, Issue:3

    Topics: Adrenergic alpha-2 Receptor Antagonists; Animals; Autoreceptors; Benzothiazoles; Brain; Dopamine; Dopamine Agonists; Dose-Response Relationship, Drug; Electrophysiology; Idazoxan; Lysergic Acid Diethylamide; Male; Neurons; Norepinephrine; Pramipexole; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1A; Receptors, Adrenergic, alpha-2; Receptors, Dopamine D2; Receptors, Dopamine D3; Serotonin; Time Factors

2009