pramipexole has been researched along with cocaine in 14 studies
| Studies (pramipexole) | Trials (pramipexole) | Recent Studies (post-2010) (pramipexole) | Studies (cocaine) | Trials (cocaine) | Recent Studies (post-2010) (cocaine) |
|---|---|---|---|---|---|
| 1,103 | 219 | 517 | 32,461 | 1,096 | 9,400 |
| Protein | Taxonomy | pramipexole (IC50) | cocaine (IC50) |
|---|---|---|---|
| Amyloid-beta precursor protein | Homo sapiens (human) | 0.338 | |
| Fatty acid-binding protein, heart | Homo sapiens (human) | 0.367 | |
| 5-hydroxytryptamine receptor 2C | Rattus norvegicus (Norway rat) | 0.0855 | |
| 5-hydroxytryptamine receptor 2A | Rattus norvegicus (Norway rat) | 0.0855 | |
| D | Rattus norvegicus (Norway rat) | 5.7544 | |
| Alpha-2B adrenergic receptor | Rattus norvegicus (Norway rat) | 5.7544 | |
| Alpha-2C adrenergic receptor | Rattus norvegicus (Norway rat) | 5.7544 | |
| Alpha-2A adrenergic receptor | Rattus norvegicus (Norway rat) | 5.7544 | |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | 1.2861 | |
| Sodium-dependent dopamine transporter | Rattus norvegicus (Norway rat) | 0.4321 | |
| 5-hydroxytryptamine receptor 2B | Rattus norvegicus (Norway rat) | 0.0855 | |
| Sodium-dependent serotonin transporter | Homo sapiens (human) | 0.5442 | |
| Sodium-dependent serotonin transporter | Rattus norvegicus (Norway rat) | 0.8885 | |
| Sodium-dependent dopamine transporter | Homo sapiens (human) | 0.3796 | |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | 5.541 | |
| Sodium-dependent dopamine transporter | Mus musculus (house mouse) | 0.2 | |
| Sigma non-opioid intracellular receptor 1 | Homo sapiens (human) | 1.05 | |
| Transporter | Rattus norvegicus (Norway rat) | 3.2277 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (14.29) | 18.2507 |
| 2000's | 7 (50.00) | 29.6817 |
| 2010's | 5 (35.71) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ferrari, F; Giuliani, D | 1 |
| Caine, SB; Everitt, BJ; Koob, GF; Parsons, LH; Schwartz, JC; Sokoloff, P | 1 |
| Guttman, M; Houle, S; Hussey, D; Kish, S; Stewart, D; Wilson, A | 1 |
| Ahlskog, JE; Maraganore, DM; Uhl, GR; Uitti, RJ | 1 |
| Davidson, C; Ellinwood, EH; King, GR; Lee, TH; Yu, GZ | 1 |
| Bergmans, P; Booij, J; Stoof, JC; van Royen, EA; Winogrodzka, A; Wolters, EC | 1 |
| Greedy, B; Grundt, P; Husbands, SM; Koffarnus, MN; Newman, AH; Woods, JH | 1 |
| Chen, J; Collins, GT; Levant, B; Truong, YN; Wang, S; Woods, JH | 1 |
| Chen, J; Collins, GT; Cunningham, AR; Newman, AH; Wang, S; Woods, JH | 1 |
| Dieb, W; Durif, F; Hafidi, A; Ouachikh, O | 1 |
| De La Garza, R; Haile, CN; Kosten, TR; Mahoney, JJ; Newton, TF; Shah, R; Verrico, CD | 1 |
| Collins, GT; France, CP | 1 |
4 trial(s) available for pramipexole and cocaine
| Article | Year |
|---|---|
Pramipexole vs levodopa as initial treatment for Parkinson disease: A randomized controlled trial. Parkinson Study Group.
Topics: Antiparkinson Agents; Benzothiazoles; Carrier Proteins; Cocaine; Corpus Striatum; Dopamine; Dopamine Agents; Dopamine Agonists; Dopamine Plasma Membrane Transport Proteins; Double-Blind Method; Dyskinesias; Female; Humans; Iodine Radioisotopes; Levodopa; Male; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Nerve Tissue Proteins; Parkinson Disease; Pramipexole; Proportional Hazards Models; Quality of Life; Radiopharmaceuticals; Thiazoles; Tomography, Emission-Computed, Single-Photon | 2000 |
Influence of L-dopa and pramipexole on striatal dopamine transporter in early PD.
Topics: Aged; Antiparkinson Agents; Benzothiazoles; Brain Chemistry; Carbon Radioisotopes; Carrier Proteins; Cocaine; Corpus Striatum; Dopamine Plasma Membrane Transport Proteins; Drug Therapy, Combination; Female; Humans; Levodopa; Male; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Nerve Tissue Proteins; Parkinson Disease; Pramipexole; Receptors, Dopamine; Thiazoles; Tomography, Emission-Computed | 2001 |
Dopamine transporter brain imaging to assess the effects of pramipexole vs levodopa on Parkinson disease progression.
Topics: Aged; Antiparkinson Agents; Benzothiazoles; Brain; Cocaine; Disease Progression; Dopamine; Dopamine Agents; Dopamine Plasma Membrane Transport Proteins; Female; Humans; Iodine Radioisotopes; Levodopa; Male; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Nerve Degeneration; Nerve Tissue Proteins; Parkinson Disease; Pramipexole; Radiopharmaceuticals; Randomized Controlled Trials as Topic; Regression Analysis; Thiazoles; Tomography, Emission-Computed, Single-Photon; Treatment Outcome | 2002 |
Dopamine D3 receptor-preferring agonist enhances the subjective effects of cocaine in humans.
Topics: Adult; Benzothiazoles; Blood Pressure; Cocaine; Cocaine-Related Disorders; Dopamine Agonists; Dose-Response Relationship, Drug; Double-Blind Method; Drug Synergism; Female; Humans; Male; Middle Aged; Pramipexole; Receptors, Dopamine D3; Reinforcement, Psychology | 2015 |
10 other study(ies) available for pramipexole and cocaine
| Article | Year |
|---|---|
Involvement of dopamine D2 receptors in the effect of cocaine on sexual behaviour and stretching-yawning of male rats.
Topics: Animals; Benzothiazoles; Cocaine; Copulation; Dopamine Agonists; Dopamine Antagonists; Lisuride; Male; Motor Activity; Pramipexole; Rats; Rats, Wistar; Receptors, Dopamine D2; Salicylamides; Sexual Behavior, Animal; Specific Pathogen-Free Organisms; Thiazoles | 1997 |
D3 receptor test in vitro predicts decreased cocaine self-administration in rats.
Topics: Animals; Benzopyrans; Benzothiazoles; Cocaine; Dopamine Agonists; Dopamine Antagonists; In Vitro Techniques; Male; Naphthalenes; Opioid-Related Disorders; Oxazines; Pramipexole; Pyrrolidines; Quinolines; Rats; Receptors, Dopamine D2; Receptors, Dopamine D3; Self Administration; Thiazoles | 1997 |
Brain imaging to assess the effects of dopamine agonists on progression of Parkinson disease.
Topics: Antiparkinson Agents; Benzothiazoles; Brain; Cocaine; Dopamine Agonists; Dopamine Plasma Membrane Transport Proteins; Humans; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Parkinson Disease; Pramipexole; Radiopharmaceuticals; Thiazoles; Tomography, Emission-Computed, Single-Photon | 2002 |
Effect of daily dosing duration of direct and indirect dopamine receptor agonists: cocaine cross-tolerance following chronic regimens.
Topics: Analysis of Variance; Animals; Area Under Curve; Autoreceptors; Benzothiazoles; Cocaine; Cocaine-Related Disorders; Cross-Over Studies; Dopamine Agonists; Dopamine Uptake Inhibitors; Drug Administration Schedule; Drug Interactions; Male; Motor Activity; Piperazines; Pramipexole; Psychomotor Performance; Rats; Rats, Sprague-Dawley; Thiazoles; Time Factors | 2002 |
[(123)I]beta-CIT SPECT is a useful method for monitoring dopaminergic degeneration in early stage Parkinson's disease.
Topics: Antiparkinson Agents; Benzothiazoles; Caudate Nucleus; Cocaine; Corpus Striatum; Disease Progression; Female; Humans; Male; Nerve Degeneration; Parkinson Disease; Pergolide; Pramipexole; Putamen; Radiopharmaceuticals; Receptors, Dopamine D2; Reproducibility of Results; Thiazoles; Tomography, Emission-Computed, Single-Photon; Treatment Outcome | 2003 |
The discriminative stimulus effects of dopamine D2- and D3-preferring agonists in rats.
Topics: Animals; Benzimidazoles; Benzothiazoles; Cocaine; Conditioning, Operant; Discrimination, Psychological; Dopamine Agonists; Dose-Response Relationship, Drug; Male; Pramipexole; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Receptors, Dopamine D3; Tetrahydronaphthalenes | 2009 |
Behavioral sensitization to cocaine in rats: evidence for temporal differences in dopamine D3 and D2 receptor sensitivity.
Topics: Animals; Basal Ganglia; Behavior, Animal; Benzothiazoles; Cocaine; Dopamine Agonists; Dose-Response Relationship, Drug; Hypothermia; Male; Motor Activity; Pramipexole; Protein Binding; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Receptors, Dopamine D3; Time Factors; Yawning | 2011 |
Effects of pramipexole on the reinforcing effectiveness of stimuli that were previously paired with cocaine reinforcement in rats.
Topics: Animals; Benzothiazoles; Cocaine; Dose-Response Relationship, Drug; Male; Pramipexole; Random Allocation; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, Dopamine D2; Reinforcement Schedule | 2012 |
Anterior ventral tegmental area dopaminergic neurons are not involved in the motivational effects of bromocriptine, pramipexole and cocaine in drug-free rats.
Topics: Animals; Benzothiazoles; Bromocriptine; Cocaine; Conditioning, Psychological; Dopamine Agonists; Dopaminergic Neurons; Male; Motivation; Motor Activity; Pramipexole; Rats; Rats, Sprague-Dawley; Ventral Tegmental Area | 2014 |
Determinants of conditioned reinforcing effectiveness: Dopamine D2-like receptor agonist-stimulated responding for cocaine-associated stimuli.
Topics: Animals; Benzothiazoles; Cocaine; Conditioning, Operant; Drug-Seeking Behavior; Male; Pramipexole; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Reinforcement, Psychology; Self Administration | 2015 |