Page last updated: 2024-09-03

pramipexole and clonazepam

pramipexole has been researched along with clonazepam in 18 studies

Compound Research Comparison

Studies
(pramipexole)
Trials
(pramipexole)
Recent Studies (post-2010)
(pramipexole)
Studies
(clonazepam)
Trials
(clonazepam)
Recent Studies (post-2010) (clonazepam)
1,1032195172,719239519

Protein Interaction Comparison

ProteinTaxonomypramipexole (IC50)clonazepam (IC50)
Gamma-aminobutyric acid receptor subunit piRattus norvegicus (Norway rat)0.0017
Gamma-aminobutyric acid receptor subunit beta-1Rattus norvegicus (Norway rat)0.0017
Gamma-aminobutyric acid receptor subunit deltaRattus norvegicus (Norway rat)0.0017
Gamma-aminobutyric acid receptor subunit gamma-2Rattus norvegicus (Norway rat)0.0017
Gamma-aminobutyric acid receptor subunit alpha-5Rattus norvegicus (Norway rat)0.0017
Gamma-aminobutyric acid receptor subunit alpha-3Rattus norvegicus (Norway rat)0.0017
Gamma-aminobutyric acid receptor subunit gamma-1Rattus norvegicus (Norway rat)0.0017
Gamma-aminobutyric acid receptor subunit alpha-2Rattus norvegicus (Norway rat)0.0017
Gamma-aminobutyric acid receptor subunit alpha-4Rattus norvegicus (Norway rat)0.0017
Gamma-aminobutyric acid receptor subunit gamma-3Rattus norvegicus (Norway rat)0.0017
Gamma-aminobutyric acid receptor subunit alpha-6Rattus norvegicus (Norway rat)0.0017
Gamma-aminobutyric acid receptor subunit alpha-1Rattus norvegicus (Norway rat)0.0017
Gamma-aminobutyric acid receptor subunit beta-3Rattus norvegicus (Norway rat)0.0017
Gamma-aminobutyric acid receptor subunit beta-2Rattus norvegicus (Norway rat)0.0017
GABA theta subunitRattus norvegicus (Norway rat)0.0017
Gamma-aminobutyric acid receptor subunit epsilonRattus norvegicus (Norway rat)0.0017

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (22.22)29.6817
2010's14 (77.78)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Andricopulo, AD; Moda, TL; Montanari, CA1
Alelyunas, YW; Bui, K; Empfield, JR; McCarthy, D; Pelosi-Kilby, L; Shen, C; Spreen, RC1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Molnar, MZ; Mucsi, I; Novak, M1
Allen, RP; Hening, W; Tenzer, P; Winkelman, JW1
Gugger, JJ; Wagner, ML1
Ji, KH; Yun, CH1
Danjo, S; Horiguchi, J; Inami, Y; Ishikawa, I; Nakamura, Y; Shinno, H; Yamanaka, M1
Hineno, T; Horiguchi, J; Inami, Y; Innami, T; Kawada, S; Mizuno, S; Nakamura, Y; Oka, Y; Otsuki, M; Sakamoto, T; Sasaki, A; Shinno, H; Tsuchiya, S1
Coburn, KL; Doonan, SM; Lauterbach, EC; Mendez, MF; Shillcutt, SD; Victoroff, J1
Auerbach, SH; Aurora, RN; Casey, KR; Chowdhuri, S; Karippot, A; Kristo, DA; Maganti, RK; Morgenthaler, TI; Ramar, K; Zak, RS1
Bozi, M; Christodoulou, C; Douzenis, A; Gasparinatos, G; Stamboulis, E; Stefanis, C; Stefanis, L; Stefanis, N1
Calvo, E; de la Llave, Y; García-Borreguero, D; Granizo, JJ; Larrosa, O; Tzonova, D; Williams, AM1
Aricò, D; Bassetti, CL; Ferini-Strambi, L; Ferri, R; Fulda, S; Manconi, M; Zucconi, M1
Inoue, Y; Matsuura, M; Sasai, T1
Della Marca, G; Frisullo, G; Iorio, R; Lo Monaco, M; Luigetti, M; Mirabella, M; Nociti, V; Servidei, S1
Nishinaka, K; Sawamura, M; Sekiya, T; Toma, K; Udaka, F; Unai, Y1
Tan, SM; Wan, YM1

Reviews

6 review(s) available for pramipexole and clonazepam

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Management of restless legs syndrome in patients on dialysis.
    Drugs, 2006, Volume: 66, Issue:5

    Topics: Amines; Anticonvulsants; Benzothiazoles; Clonazepam; Cyclohexanecarboxylic Acids; Dopamine Agents; Gabapentin; gamma-Aminobutyric Acid; Humans; Kidney Failure, Chronic; Levodopa; Narcotics; Pramipexole; Renal Dialysis; Restless Legs Syndrome; Thiazoles; Uremia

2006
Restless legs syndrome: nonpharmacologic and pharmacologic treatments.
    Geriatrics, 2007, Volume: 62, Issue:10

    Topics: Amines; Anemia, Iron-Deficiency; Anticonvulsants; Benzothiazoles; Clonazepam; Cyclohexanecarboxylic Acids; Dopamine Agents; Dopamine Agonists; Ferritins; Gabapentin; gamma-Aminobutyric Acid; Humans; Indoles; Iron; Levodopa; Pramipexole; Restless Legs Syndrome; Trace Elements

2007
Rapid eye movement sleep behavior disorder.
    The Annals of pharmacotherapy, 2007, Volume: 41, Issue:11

    Topics: Anticonvulsants; Antiparkinson Agents; Benzothiazoles; Clonazepam; Comorbidity; Dopamine Agonists; GABA Modulators; Humans; Melatonin; Parkinson Disease; Pramipexole; REM Sleep Behavior Disorder

2007
Psychopharmacological neuroprotection in neurodegenerative disease: assessing the preclinical data.
    The Journal of neuropsychiatry and clinical neurosciences, 2010,Winter, Volume: 22, Issue:1

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Antioxidants; Antipsychotic Agents; Benzodiazepines; Benzothiazoles; Brain; Clonazepam; Desipramine; Dibenzothiazepines; Dopamine Agonists; Humans; Lithium Carbonate; Maprotiline; Melatonin; Neurodegenerative Diseases; Neuroprotective Agents; Olanzapine; Parkinson Disease; Pramipexole; Quetiapine Fumarate; Selective Serotonin Reuptake Inhibitors; Valproic Acid

2010
Pramipexole in the treatment of REM sleep behaviour disorder: A critical review.
    Psychiatry research, 2016, Sep-30, Volume: 243

    Topics: Benzothiazoles; Clonazepam; Dopamine Agonists; Humans; Observational Studies as Topic; Polysomnography; Pramipexole; REM Sleep Behavior Disorder; Sleep, REM; Treatment Outcome

2016

Trials

3 trial(s) available for pramipexole and clonazepam

ArticleYear
Proposed dose equivalence between clonazepam and pramipexole in patients with restless legs syndrome.
    Progress in neuro-psychopharmacology & biological psychiatry, 2010, Apr-16, Volume: 34, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antioxidants; Benzothiazoles; Clonazepam; Dose-Response Relationship, Drug; Female; GABA Modulators; Humans; Male; Middle Aged; Pramipexole; Prospective Studies; Restless Legs Syndrome; Severity of Illness Index

2010
Dissociation of periodic leg movements from arousals in restless legs syndrome.
    Annals of neurology, 2012, Volume: 71, Issue:6

    Topics: Anticonvulsants; Antiparkinson Agents; Arousal; Benzothiazoles; Clonazepam; Electroencephalography; Female; Humans; Leg; Male; Movement; Pain Measurement; Periodicity; Polysomnography; Pramipexole; Prospective Studies; Restless Legs Syndrome; Single-Blind Method

2012
Factors associated with the effect of pramipexole on symptoms of idiopathic REM sleep behavior disorder.
    Parkinsonism & related disorders, 2013, Volume: 19, Issue:2

    Topics: Aged; Antiparkinson Agents; Benzothiazoles; Clonazepam; Female; Humans; Male; Middle Aged; Pramipexole; REM Sleep Behavior Disorder

2013

Other Studies

9 other study(ies) available for pramipexole and clonazepam

ArticleYear
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
Experimental solubility profiling of marketed CNS drugs, exploring solubility limit of CNS discovery candidate.
    Bioorganic & medicinal chemistry letters, 2010, Dec-15, Volume: 20, Issue:24

    Topics: Central Nervous System Agents; Drug Evaluation, Preclinical; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Solubility

2010
Zolpidem-induced sleep-related eating disorder.
    Journal of the neurological sciences, 2010, Jan-15, Volume: 288, Issue:1-2

    Topics: Benzothiazoles; Clonazepam; Dopamine Agonists; Feeding and Eating Disorders; Humans; Hypnotics and Sedatives; Male; Middle Aged; Pramipexole; Pyridines; Restless Legs Syndrome; Sleep Wake Disorders; Zolpidem

2010
Successful treatment of restless legs syndrome with the herbal prescription Yokukansan.
    Progress in neuro-psychopharmacology & biological psychiatry, 2010, Feb-01, Volume: 34, Issue:1

    Topics: Aged; Aged, 80 and over; Anticonvulsants; Antioxidants; Benzothiazoles; Clonazepam; Drugs, Chinese Herbal; Female; Humans; Male; Middle Aged; Pramipexole; Restless Legs Syndrome

2010
Best practice guide for the treatment of REM sleep behavior disorder (RBD).
    Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2010, Feb-15, Volume: 6, Issue:1

    Topics: Benzothiazoles; Central Nervous System Depressants; Clonazepam; Dopamine Agonists; GABA Modulators; Humans; Melatonin; Pramipexole; REM Sleep Behavior Disorder

2010
Isolated delusional syndrome in Parkinson's Disease.
    Parkinsonism & related disorders, 2010, Volume: 16, Issue:8

    Topics: Aged; Amantadine; Antiparkinson Agents; Benserazide; Benzothiazoles; Catechols; Clonazepam; Female; Humans; Indans; Indoles; Levodopa; Male; Middle Aged; Nitriles; Parkinson Disease; Pramipexole; Schizophrenia, Paranoid; Syndrome

2010
Breakthrough symptoms during the daytime in patients with restless legs syndrome (Willis-Ekbom disease).
    Sleep medicine, 2012, Volume: 13, Issue:2

    Topics: Adult; Aged; Benzothiazoles; Circadian Rhythm; Clonazepam; Cross-Sectional Studies; Dopamine Agonists; Female; GABA Modulators; Health Surveys; Humans; Indoles; Male; Middle Aged; Pramipexole; Prevalence; Restless Legs Syndrome; Tetrahydronaphthalenes; Thiophenes; Treatment Outcome

2012
A Case of Hemiabdominal Myoclonus.
    Clinical EEG and neuroscience, 2015, Volume: 46, Issue:4

    Topics: Abdominal Muscles; Aged; Anticonvulsants; Benzothiazoles; Clonazepam; Diagnosis, Differential; Dopamine Agonists; Drug Therapy, Combination; Electroencephalography; Electromyography; Female; Humans; Magnetic Resonance Imaging; Myoclonus; Pramipexole

2015
[A case of Parkinson's disease following restless genial sensation].
    Rinsho shinkeigaku = Clinical neurology, 2015, Volume: 55, Issue:4

    Topics: Benzothiazoles; Clonazepam; Drug Therapy, Combination; Female; Humans; Middle Aged; Parkinsonian Disorders; Pramipexole; Restless Legs Syndrome; Sexual Dysfunctions, Psychological; Treatment Outcome

2015