Compounds > pramipexole
Page last updated: 2024-09-03

pramipexole and benztropine

pramipexole has been researched along with benztropine in 2 studies

Compound Research Comparison

Studies
(pramipexole)		Trials
(pramipexole)		Recent Studies (post-2010)
(pramipexole)		Studies
(benztropine)		Trials
(benztropine)		Recent Studies (post-2010) (benztropine)
1,1032195177359385

Protein Interaction Comparison

ProteinTaxonomypramipexole (IC50)benztropine (IC50)
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)0.061
Aldo-keto reductase family 1 member B1Rattus norvegicus (Norway rat)1.391
Muscarinic acetylcholine receptor M2Homo sapiens (human)0.0366
Muscarinic acetylcholine receptor M4Homo sapiens (human)0.0037
Muscarinic acetylcholine receptor M5Homo sapiens (human)0.002
Alpha-2A adrenergic receptorHomo sapiens (human)0.544
Muscarinic acetylcholine receptor M1Homo sapiens (human)0.0005
Alpha-2B adrenergic receptorHomo sapiens (human)0.065
Alpha-2C adrenergic receptorHomo sapiens (human)0.395
Muscarinic acetylcholine receptor M3Homo sapiens (human)0.0106
Sodium-dependent noradrenaline transporter Homo sapiens (human)1.391
Histamine H2 receptorHomo sapiens (human)1.206
Alpha-1D adrenergic receptorHomo sapiens (human)0.052
5-hydroxytryptamine receptor 2AHomo sapiens (human)0.024
5-hydroxytryptamine receptor 2CHomo sapiens (human)0.061
Histamine H1 receptorHomo sapiens (human)0.0032
D(3) dopamine receptorHomo sapiens (human)0.654
5-hydroxytryptamine receptor 2BHomo sapiens (human)0.2
5-hydroxytryptamine receptor 6Homo sapiens (human)2.788
Sodium-dependent dopamine transporter Homo sapiens (human)0.2948
Sigma non-opioid intracellular receptor 1Homo sapiens (human)0.139

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Agúndez, JA; Alonso-Navarro, H; García-Martín, E; Jiménez-Jiménez, FJ1

Reviews

2 review(s) available for pramipexole and benztropine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Anti-Parkinson's disease drugs and pharmacogenetic considerations.
    Expert opinion on drug metabolism & toxicology, 2013, Volume: 9, Issue:7

    Topics: Aryl Hydrocarbon Hydroxylases; Benzothiazoles; Benztropine; Bromocriptine; Cabergoline; Catechols; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 CYP2B6; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP3A; Ergolines; Genetic Markers; Humans; Indans; Indoles; Levodopa; Lisuride; Nitriles; Parkinson Disease; Pergolide; Pharmacogenetics; Pramipexole; Receptors, Dopamine D2; Receptors, Dopamine D3; Reproducibility of Results; Selegiline

2013