Page last updated: 2024-09-03

pramipexole and 1-methyl-4-phenylpyridinium

pramipexole has been researched along with 1-methyl-4-phenylpyridinium in 9 studies

Compound Research Comparison

Studies
(pramipexole)
Trials
(pramipexole)
Recent Studies (post-2010)
(pramipexole)
Studies
(1-methyl-4-phenylpyridinium)
Trials
(1-methyl-4-phenylpyridinium)
Recent Studies (post-2010) (1-methyl-4-phenylpyridinium)
1,1032195171,8541593

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (33.33)18.2507
2000's6 (66.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kitamura, Y; Kohno, Y; Nakazawa, M; Nomura, Y1
Bennett, JP; Cassarino, DS; Fall, CP; Smith, TS1
Kakimura, JI; Kitamura, Y; Kohno, Y; Kosaka, T; Matsuoka, Y; Nomura, Y; Taniguchi, T1
Abramova, NN; Bennett, JP; Cassarino, DS; Halvorsen, EM; Parker, WD; Sturgill, TW; Swerdlow, RH1
Kakimura, J; Kitamura, Y; Kohno, Y; Nomura, Y; Takata, K; Taniguchi, T1
Abramova, NA; Bennett, JP; Cassarino, DS; Khan, SM; Painter, TW1
Borwege, S; Hagner, D; Joyce, JN; Millan, MJ; Osredkar, T; PazSoldan, M; Presgraves, S; Renish, L; Replogle, M1
Borwege, S; Joyce, JN; Millan, MJ; Presgraves, SP1
Cooper, JM; Gu, M; Iravani, MM; Irvani, M; Jenner, P; King, D; Schapira, AH1

Other Studies

9 other study(ies) available for pramipexole and 1-methyl-4-phenylpyridinium

ArticleYear
Inhibitory effects of talipexole and pramipexole on MPTP-induced dopamine reduction in the striatum of C57BL/6N mice.
    Japanese journal of pharmacology, 1997, Volume: 74, Issue:1

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; 3,4-Dihydroxyphenylacetic Acid; Animals; Azepines; Benzothiazoles; Bromocriptine; Dopamine; Dopamine Agents; Dopamine Agonists; Homovanillic Acid; In Vitro Techniques; Injections, Intraperitoneal; Male; Mice; Mice, Inbred C57BL; Neostriatum; Pramipexole; Synaptosomes; Thiazoles

1997
Pramipexole reduces reactive oxygen species production in vivo and in vitro and inhibits the mitochondrial permeability transition produced by the parkinsonian neurotoxin methylpyridinium ion.
    Journal of neurochemistry, 1998, Volume: 71, Issue:1

    Topics: 1-Methyl-4-phenylpyridinium; Animals; Antiparkinson Agents; Benzothiazoles; Biological Transport; Calcium; Corpus Striatum; Dopamine Agents; Humans; Ion Channel Gating; Liver; Male; Microdialysis; Mitochondria; Neuroblastoma; Neuroprotective Agents; Neurotoxins; Parkinson Disease, Secondary; Phosphorus; Porins; Pramipexole; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Thiazoles; Tumor Cells, Cultured

1998
Protective effects of the antiparkinsonian drugs talipexole and pramipexole against 1-methyl-4-phenylpyridinium-induced apoptotic death in human neuroblastoma SH-SY5Y cells.
    Molecular pharmacology, 1998, Volume: 54, Issue:6

    Topics: 1-Methyl-4-phenylpyridinium; Antiparkinson Agents; Apoptosis; Azepines; Benzothiazoles; Bromocriptine; Bucladesine; Caspase 3; Caspases; Dopamine Agonists; Humans; Pramipexole; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Thiazoles; Tumor Cells, Cultured; Tumor Suppressor Protein p53

1998
Interaction among mitochondria, mitogen-activated protein kinases, and nuclear factor-kappaB in cellular models of Parkinson's disease.
    Journal of neurochemistry, 2000, Volume: 74, Issue:4

    Topics: 1-Methyl-4-phenylpyridinium; Adenine Nucleotides; Benzothiazoles; Electron Transport; Enzyme Activation; Free Radical Scavengers; Herbicides; Humans; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase Kinase 1; Mitochondria; Mitogen-Activated Protein Kinases; Neuroblastoma; Neurons; NF-kappa B; Oxidative Stress; Parkinson Disease; Peptides; Pramipexole; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-raf; Signal Transduction; Superoxide Dismutase; Thiazoles; Tumor Cells, Cultured

2000
Release and aggregation of cytochrome c and alpha-synuclein are inhibited by the antiparkinsonian drugs, talipexole and pramipexole.
    European journal of pharmacology, 2001, Apr-06, Volume: 417, Issue:1-2

    Topics: 1-Methyl-4-phenylpyridinium; alpha-Synuclein; Antiparkinson Agents; Azepines; Benzothiazoles; Caspases; Cell-Free System; Cytochrome c Group; Cytosol; Deoxyadenine Nucleotides; Dose-Response Relationship, Drug; Enzyme Activation; Humans; Nerve Tissue Proteins; Organelles; Pramipexole; Synucleins; Thiazoles; Tumor Cells, Cultured

2001
Inhibition by R(+) or S(-) pramipexole of caspase activation and cell death induced by methylpyridinium ion or beta amyloid peptide in SH-SY5Y neuroblastoma.
    Journal of neuroscience research, 2002, Feb-15, Volume: 67, Issue:4

    Topics: 1-Methyl-4-phenylpyridinium; Alzheimer Disease; Amyloid beta-Peptides; Anti-Bacterial Agents; Aristolochic Acids; Benzothiazoles; Bongkrekic Acid; Brain; Caspase Inhibitors; Caspases; Cell Death; Dose-Response Relationship, Drug; Enzyme Inhibitors; Free Radical Scavengers; Humans; Neuroblastoma; Neurodegenerative Diseases; Neurons; Parkinson Disease; Peptide Fragments; Phenanthrenes; Pramipexole; Thiazoles; Tumor Cells, Cultured

2002
Neuroprotective effects of the novel D3/D2 receptor agonist and antiparkinson agent, S32504, in vitro against 1-methyl-4-phenylpyridinium (MPP+) and in vivo against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP): a comparison to ropinirole.
    Experimental neurology, 2003, Volume: 184, Issue:1

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Animals; Antiparkinson Agents; Benzothiazoles; Cell Count; Cell Line; DNA; Dopamine Agents; Dopamine Agonists; Humans; Immunohistochemistry; Indoles; Male; Mice; Mice, Inbred C57BL; Neuroprotective Agents; Oxazines; Pramipexole; Receptors, Dopamine D2; Receptors, Dopamine D3; Tetrazolium Salts; Thiazoles

2003
Involvement of dopamine D(2)/D(3) receptors and BDNF in the neuroprotective effects of S32504 and pramipexole against 1-methyl-4-phenylpyridinium in terminally differentiated SH-SY5Y cells.
    Experimental neurology, 2004, Volume: 190, Issue:1

    Topics: 1-Methyl-4-phenylpyridinium; Antibodies; Benzothiazoles; Brain-Derived Neurotrophic Factor; Cell Differentiation; Cell Line; Dopamine Agonists; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Enzyme Inhibitors; Humans; Neuroblastoma; Neurons; Neuroprotective Agents; Oxazines; Pramipexole; Receptors, Dopamine D2; Receptors, Dopamine D3; Tetradecanoylphorbol Acetate; Thiazoles; Tretinoin

2004
Pramipexole protects against apoptotic cell death by non-dopaminergic mechanisms.
    Journal of neurochemistry, 2004, Volume: 91, Issue:5

    Topics: 1-Methyl-4-phenylpyridinium; Aconitate Hydratase; Antioxidants; Benzothiazoles; Carbocyanines; Caspase 3; Caspases; Cell Count; Cell Death; Cell Line, Tumor; Cell Survival; Cytochromes c; Dose-Response Relationship, Drug; Drug Interactions; Flow Cytometry; Humans; Jurkat Cells; L-Lactate Dehydrogenase; Mitochondria; Necrosis; Neuroblastoma; Pramipexole; Rotenone; Thiazoles

2004