Compounds > pralidoxime chloride
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pralidoxime chloride and bis-(4-hydroxyiminomethylpyridinium)-2-trans-butene dibromide

pralidoxime chloride has been researched along with bis-(4-hydroxyiminomethylpyridinium)-2-trans-butene dibromide in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dohnal, V; Dolezal, M; Jun, D; Kuca, K; Musilek, K1
Dohnal, V; Dolezal, M; Holas, O; Jun, D; Kuca, K; Musilek, K; Opletalova, V1
Dohnal, V; Dolezal, M; Gunn-Moore, F; Holas, O; Jun, D; Kuca, K; Musilek, K; Opletalova, V1
Cabal, J; Gunn-Moore, F; Jun, D; Kassa, J; Kuca, K; Musilek, K1
Chae, CH; Jeong, HC; Jung, YS; Kassa, J; Kuca, K; Musilek, K; Park, NJ1

Other Studies

5 other study(ies) available for pralidoxime chloride and bis-(4-hydroxyiminomethylpyridinium)-2-trans-butene dibromide

ArticleYear
Synthesis of the novel series of bispyridinium compounds bearing (E)-but-2-ene linker and evaluation of their reactivation activity against chlorpyrifos-inhibited acetylcholinesterase.
    Bioorganic & medicinal chemistry letters, 2006, Volume: 16, Issue:3

    Topics: Acetylcholinesterase; Animals; Chlorpyrifos; Cholinesterase Inhibitors; Cholinesterase Reactivators; Dose-Response Relationship, Drug; Hydrocarbons, Brominated; Nitrogen; Oximes; Pyridinium Compounds; Rats

2006
Novel series of bispyridinium compounds bearing a (Z)-but-2-ene linker--synthesis and evaluation of their reactivation activity against tabun and paraoxon-inhibited acetylcholinesterase.
    Bioorganic & medicinal chemistry letters, 2007, Jun-01, Volume: 17, Issue:11

    Topics: Acetylcholinesterase; Butanes; Cholinesterase Inhibitors; Cholinesterase Reactivators; Humans; Organophosphates; Oximes; Paraoxon; Pyridinium Compounds

2007
Monooxime reactivators of acetylcholinesterase with (E)-but-2-ene linker: preparation and reactivation of tabun- and paraoxon-inhibited acetylcholinesterase.
    Bioorganic & medicinal chemistry, 2007, Nov-01, Volume: 15, Issue:21

    Topics: Acetylcholinesterase; Animals; Antidotes; Cholinesterase Inhibitors; Cholinesterase Reactivators; Drug Design; Organophosphates; Oximes; Paraoxon; Rats; Structure-Activity Relationship

2007
Design of a potent reactivator of tabun-inhibited acetylcholinesterase--synthesis and evaluation of (E)-1-(4-carbamoylpyridinium)-4-(4-hydroxyiminomethylpyridinium)-but-2-ene dibromide (K203).
    Journal of medicinal chemistry, 2007, Nov-01, Volume: 50, Issue:22

    Topics: Acetylcholinesterase; Chemical Warfare Agents; Cholinesterase Inhibitors; Cholinesterase Reactivators; Drug Design; Kinetics; Organophosphates; Oximes; Pyridinium Compounds; Structure-Activity Relationship

2007
Fluorinated pyridinium oximes as potential reactivators for acetylcholinesterases inhibited by paraoxon organophosphorus agent.
    Bioorganic & medicinal chemistry, 2009, Sep-01, Volume: 17, Issue:17

    Topics: Acetylcholinesterase; Cholinesterase Inhibitors; Cholinesterase Reactivators; Erythrocytes; Halogenation; Humans; Oximes; Paraoxon; Pyridinium Compounds

2009