Page last updated: 2024-08-16

practolol and metoprolol

practolol has been researched along with metoprolol in 93 studies

Research

Studies (93)

Timeframe	Studies, this research(%)	All Research%
pre-1990	75 (80.65)	18.7374
1990's	5 (5.38)	18.2507
2000's	8 (8.60)	29.6817
2010's	5 (5.38)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET	1
Binet, JL; Cavero, IG; Lefèvre-Borg, F; Manoury, PM; Rousseau, J	1
Carrupt, PA; el Tayar, N; Testa, B; Van de Waterbeemd, H	1
Baldwin, JJ; Denny, GH; Freedman, MB; Gross, DM; Hirschmann, R; Ponticello, GS; Sweet, CS	1
Artursson, P; Beigi, F; Lundahl, P; Luthman, K; Palm, K; Strandlund, G; Ungell, AL	1
Iakovidis, D; Jackman, GP; Louis, SN; Louis, WJ; Nero, TL	1
Ghuloum, AM; Jain, AN; Sage, CR	1
Ertl, P; Rohde, B; Selzer, P	1
Artursson, P; Luthman, K; Norinder, U; Stenberg, P	1
Baker, JG	1
Caron, G; Ermondi, G	1
Akamatsu, M; Fujikawa, M; Nakao, K; Shimizu, R	1
Abraham, MH; Acree, WE; Ibrahim, A	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S	1
Campillo, NE; Guerra, A; Páez, JA	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
Akamatsu, M	1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K	1
Barber, S; Dew, TP; Farrell, TL; Poquet, L; Williamson, G	1
Besterman, EM; Comerford, MB	1
Levy, JV	1
Chubb, IW; Raine, AE	1
Boorsma, M; Meems, L; Zaagsma, J	1
Meier, J	1
Gooren, L; Harms, HH; Hesse, C; Spoelstra, AJ; Verschoor, L	1
Keyriläinen, O; Uusitalo, A	1
Kiechel, JR; Meier, J	1
Tannenbaum, H	1
Bellucci, R; Bonomi, L; Massa, F; Noya, E; Perfetti, S	1
Dunstan, R; Jackson, DM	1
Camanni, F; Massara, F; Molinatti, GM	1
Florin-Christensen, A; Marshall, NJ; von Borcke, S	1
Kittel, E; Philippu, A	1
Malchoff, CD; Marinetti, GV	1
Formgren, H	2
Ekelund, LG; Orö, L	1
Davidson, C; Singleton, W; Taylor, SH; Thadani, U	2
Frick, MH; Virtanen, K	1
Luck, MR; Münker, M	1
Acuña, D; Castillo, MA; García-Torres, L; Haro, JM; Vargas, F	1
Anderson, GF; Dhabuwala, CB; Ramakrishna, CV	1
Bibra, HV; Klein, G; Sauer, E; Wirtzfeld, A	1
Lyrenäs, E	1
Bjellin, LA; Ek, BA; Lundgren, BT	1
Fishbein, L; Jackson, CD	1
Abrahamsson, H; Lyrenäs, E	1
Lathers, CM; Spivey, WH	1
Lindvall, K; Personne, M; Sjögren, A	1
Hartling, OJ; Svendsen, TL; Trap-Jensen, J	1
Giorgetti, F; Re, L; Rossini, L	1
Re, L; Rossini, L	1
Himmler, FC; Klein, G; Schmidt, G; Wirtzfeld, A	1
Besch, HR; Manalan, AS; Watanabe, AM	1
Alkondon, M; Bhatia, S; Sen, P; Sivam, SP	1
Graham, JR	1
Lee, PS; Silke, B; Taylor, SH	1
Brotelle, R; Colot, M; de Clavière, M; Heyndrickx, JP	1
Lochan, R; Silke, B; Taylor, SH	1
Ek, B; Lundgren, B	1
Ablad, B; Aurell, M; Kopp, U; Svensson, L	1
Bernauer, W	1
Hjalmarson, A	1
Harden, TK; McCarthy, KD	1
Csapo, G; Kalusche, D; Keck, M; Weisswange, A	1
Kulling, P	1
Andersson, T; Heath, A; Mattsson, H	1
Carlsson, E; Hedberg, A; Mattsson, H	1
Amery, A; Bulpitt, C; Cattaert, A; Fagard, R; Staessen, J; Vanhees, L	1
Danielsson, A; Henriksson, R; Lindström, P; Sehlin, J	1
Brandi, ML; Rotella, CM; Toccafondi, RS; Zonefrati, R	1
Hilal, A; Lee, PS; Silke, B; Taylor, SH	1
Gabrielsson, M; Heath, A; Redgårdh, CG	1
Pratt, CM; Roberts, R	1
Löfdahl, CG; Marlin, GE; Svedmyr, N	1
Friedewald, WT; Frishman, WH; Furberg, CD	1
Tomov, I	1
Ekström, J; Malmberg, L	1
Dahlström, U; Nylander, E	1
Carlsöö, B; Danielsson, A; Henriksson, R	1
Ferrante, M; Kobayashi, H; Maoret, T; Spano, P; Trabucchi, M	1
Engel, G	1
Hilakivi, I	1
Anderson, GF; Marks, BH	1
Greefhorst, AP; van Herwaarden, CL	1
Bennetts, FE; Clarke, I; Rollason, WN	1
Hynynen, M; Lindgren, L; Saarnivaara, L	1
Hulting, J; Wallin, CJ	1
Hervonen, H; Rechardt, L	1
Carlsen, JE; Hartling, OJ; Svendsen, TL; Trap-Jensen, J	1
Raza, A	1

Reviews

7 review(s) available for practolol and metoprolol

Article	Year
Modeling of beta-adrenoceptors based on molecular electrostatic potential studies of agonists and antagonists. Journal of medicinal chemistry, 1988, Volume: 31, Issue:11 Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Models, Molecular; Receptors, Adrenergic, beta; Structure-Activity Relationship	1988
[Comparative pharmacokinetics of beta-blockers]. La Nouvelle presse medicale, 1978, Sep-20, Volume: 7, Issue:31 Topics: Acebutolol; Adrenergic beta-Antagonists; Alprenolol; Animals; Atenolol; Half-Life; Humans; Metoprolol; Oxprenolol; Pindolol; Practolol; Propranolol; Sotalol; Timolol	1978
[Long-term utilization of beta-blockers in arterial hypertension]. La Nouvelle presse medicale, 1978, Sep-20, Volume: 7, Issue:31 Topics: Acebutolol; Adrenergic beta-Antagonists; Alprenolol; Blood Pressure; Coronary Disease; Drug Tolerance; Heart Rate; Humans; Hypertension; Metoprolol; Pindolol; Practolol; Time Factors	1978
A toxicological review of beta-adrenergic blockers. Fundamental and applied toxicology : official journal of the Society of Toxicology, 1986, Volume: 6, Issue:3 Topics: Acebutolol; Adrenergic beta-Antagonists; Alprenolol; Animals; Atenolol; Cocarcinogenesis; Ethanolamines; Female; Kinetics; Labetalol; Lethal Dose 50; Male; Metoprolol; Mice; Mutagens; Nadolol; Neoplasms, Experimental; Oxprenolol; Pindolol; Practolol; Propanolamines; Propranolol; Rats; Sotalol; Timolol	1986
Beta blocking agents: current status in the prevention of sudden coronary death. Annals of the New York Academy of Sciences, 1982, Volume: 382 Topics: Adrenergic beta-Antagonists; Adult; Aged; Alprenolol; Atenolol; Clinical Trials as Topic; Coronary Disease; Death, Sudden; Female; Humans; Male; Metoprolol; Middle Aged; Myocardial Infarction; Practolol; Propranolol; Prospective Studies; Random Allocation; Timolol	1982
The use of beta-adrenergic blocking drugs in patients with myocardial infarction. Current problems in cardiology, 1984, Volume: 9, Issue:3 Topics: Adrenergic beta-Antagonists; Alprenolol; Angina Pectoris; Atenolol; Clinical Trials as Topic; Humans; Hypertension; Metoprolol; Myocardial Infarction; Oxprenolol; Pindolol; Practolol; Propranolol; Receptors, Adrenergic, beta; Risk; Sotalol; Timolol	1984
[Therapeutic value of the long-term administration of beta-adrenergic blockaders after myocardial infarct]. Vutreshni bolesti, 1984, Volume: 23, Issue:3 Topics: Adrenergic beta-Antagonists; Alprenolol; Clinical Trials as Topic; Humans; Metoprolol; Myocardial Infarction; Placebos; Practolol; Propranolol; Random Allocation; Sotalol; Time Factors; Timolol	1984

Trials

14 trial(s) available for practolol and metoprolol

Article	Year
An eighteen months' study of the clinical response to metoprolol, a selective beta1-receptor blocking agent, in patients with angina pectoris. Postgraduate medical journal, 1976, Volume: 52, Issue:610 Topics: Adrenergic beta-Antagonists; Adult; Aged; Angina Pectoris; Clinical Trials as Topic; Exercise Test; Female; Follow-Up Studies; Humans; Male; Metoprolol; Middle Aged; Practolol; Propanolamines; Propranolol	1976
A comparative study of three beta 1-adrenoreceptor blocking drugs with different degree of intrinsic stimulating activity (metoprolol, practolol and H 87/07) in patients with angina pectoris. Annals of clinical research, 1978, Volume: 10, Issue:4 Topics: Adrenergic beta-Antagonists; Angina Pectoris; Blood Pressure; Heart Rate; Humans; Metoprolol; Physical Exertion; Practolol; Propanolamines	1978
Antianginal efficiency of nifedipine with and without a beta-blocker, studied with exercise test. A double-blind, randomized subacute study. Clinical cardiology, 1979, Volume: 2, Issue:3 Topics: Aged; Alprenolol; Angina Pectoris; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Exercise Test; Female; Heart Rate; Humans; Male; Metoprolol; Middle Aged; Nifedipine; Placebos; Practolol; Pyridines	1979
Comparison of the immediate effects of five beta-adrenoreceptor-blocking drugs with different ancillary properties in angina pectoris. The New England journal of medicine, 1979, Apr-05, Volume: 300, Issue:14 Topics: Adult; Angina Pectoris; Blood Pressure; Dose-Response Relationship, Drug; Drug Evaluation; Electrocardiography; Exercise Test; Heart Rate; Humans; Male; Metoprolol; Middle Aged; Oxprenolol; Practolol; Propanolamines; Propranolol	1979
Beta adrenergic influence on oesophageal peristalsis in man. Gut, 1986, Volume: 27, Issue:3 Topics: Adrenergic beta-Agonists; Adult; Esophagus; Female; Humans; Male; Metoprolol; Middle Aged; Peristalsis; Practolol; Prenalterol; Pressure; Propranolol; Terbutaline	1986
Comparison of five beta-adrenoreceptor antagonists with different ancillary properties during sustained twice daily therapy in angina pectoris. The American journal of medicine, 1980, Volume: 68, Issue:2 Topics: Adrenergic beta-Antagonists; Adult; Angina Pectoris; Blood Pressure; Double-Blind Method; Exercise Test; Female; Heart Rate; Humans; Male; Metoprolol; Middle Aged; Oxprenolol; Physical Exertion; Placebos; Practolol; Propanolamines; Propranolol; Time Factors	1980
Intravenous beta-blockade in coronary heart disease: is cardioselectivity or intrinsic sympathomimetic activity hemodynamically useful? The New England journal of medicine, 1982, Mar-18, Volume: 306, Issue:11 Topics: Adrenergic beta-Antagonists; Adult; Blood Pressure; Clinical Trials as Topic; Coronary Disease; Heart; Heart Rate; Heart Ventricles; Hemodynamics; Humans; Metoprolol; Middle Aged; Oxprenolol; Practolol; Propranolol; Random Allocation; Sympathetic Nervous System; Vascular Resistance	1982
Speed of onset of pharmacodynamic activity of propranolol, practolol, oxprenolol and metoprolol after intravenous infection in man. British journal of clinical pharmacology, 1981, Volume: 12, Issue:5 Topics: Adrenergic beta-Antagonists; Adult; Aged; Female; Heart Rate; Humans; Injections, Intravenous; Male; Metoprolol; Middle Aged; Oxprenolol; Practolol; Propranolol; Time Factors	1981
Beta blocking agents: current status in the prevention of sudden coronary death. Annals of the New York Academy of Sciences, 1982, Volume: 382 Topics: Adrenergic beta-Antagonists; Adult; Aged; Alprenolol; Atenolol; Clinical Trials as Topic; Coronary Disease; Death, Sudden; Female; Humans; Male; Metoprolol; Middle Aged; Myocardial Infarction; Practolol; Propranolol; Prospective Studies; Random Allocation; Timolol	1982
Secondary prevention with beta-adrenoceptor blockers in post-myocardial infarction patients. American heart journal, 1982, Volume: 104, Issue:6 Topics: Adrenergic beta-Antagonists; Clinical Trials as Topic; Double-Blind Method; Humans; Metoprolol; Myocardial Infarction; Oxprenolol; Practolol; Propranolol; Recurrence; Sotalol; Timolol	1982
Chronic beta blockade therapy in patients after myocardial infarction. The American journal of cardiology, 1983, Oct-01, Volume: 52, Issue:7 Topics: Adrenergic beta-Antagonists; Aged; Alprenolol; Clinical Trials as Topic; Double-Blind Method; Humans; Metoprolol; Myocardial Infarction; Practolol; Propranolol; Timolol	1983
The use of beta-adrenergic blocking drugs in patients with myocardial infarction. Current problems in cardiology, 1984, Volume: 9, Issue:3 Topics: Adrenergic beta-Antagonists; Alprenolol; Angina Pectoris; Atenolol; Clinical Trials as Topic; Humans; Hypertension; Metoprolol; Myocardial Infarction; Oxprenolol; Pindolol; Practolol; Propranolol; Receptors, Adrenergic, beta; Risk; Sotalol; Timolol	1984
[Therapeutic value of the long-term administration of beta-adrenergic blockaders after myocardial infarct]. Vutreshni bolesti, 1984, Volume: 23, Issue:3 Topics: Adrenergic beta-Antagonists; Alprenolol; Clinical Trials as Topic; Humans; Metoprolol; Myocardial Infarction; Placebos; Practolol; Propranolol; Random Allocation; Sotalol; Time Factors; Timolol	1984
The effect of metoprolol and practolol on lung function and blood pressure in hypertensive asthmatics. British journal of clinical pharmacology, 1976, Volume: 3, Issue:6 Topics: Adrenergic beta-1 Receptor Antagonists; Adult; Aged; Blood Pressure; Cross-Over Studies; Double-Blind Method; Female; Forced Expiratory Volume; Heart Rate; Humans; Hypertension; Lung; Male; Metoprolol; Middle Aged; Practolol	1976

Other Studies

75 other study(ies) available for practolol and metoprolol

Article	Year
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs. Journal of medicinal chemistry, 1985, Volume: 28, Issue:3 Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium	1985
Synthesis of a series of compounds related to betaxolol, a new beta 1-adrenoceptor antagonist with a pharmacological and pharmacokinetic profile optimized for the treatment of chronic cardiovascular diseases. Journal of medicinal chemistry, 1987, Volume: 30, Issue:6 Topics: Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Antihypertensive Agents; Betaxolol; Biotransformation; Cardiovascular Diseases; Chronic Disease; Female; Guinea Pigs; In Vitro Techniques; Kinetics; Male; Propanolamines; Rana esculenta; Rats; Structure-Activity Relationship	1987
Beta 1-selective adrenoceptor antagonists: examples of the 2-[4-[3-(substituted-amino)-2-hydroxypropoxy]phenyl]imidazole class. Journal of medicinal chemistry, 1983, Volume: 26, Issue:7 Topics: Adrenergic alpha-Agonists; Animals; Female; Guinea Pigs; Heart; Imidazoles; Indicators and Reagents; Isoproterenol; Magnetic Resonance Spectroscopy; Receptors, Adrenergic; Receptors, Adrenergic, beta; Structure-Activity Relationship	1983
Evaluation of dynamic polar molecular surface area as predictor of drug absorption: comparison with other computational and experimental predictors. Journal of medicinal chemistry, 1998, Dec-31, Volume: 41, Issue:27 Topics: Adrenergic beta-Antagonists; Amides; Biological Transport; Caco-2 Cells; Chromatography, Liquid; Drug Design; Epithelial Cells; Formamides; Humans; Intestinal Absorption; Liposomes; Models, Molecular; Molecular Conformation; Monte Carlo Method; Permeability; Propanolamines; Structure-Activity Relationship	1998
LK 204-545, a highly selective beta1-adrenoceptor antagonist at human beta-adrenoceptors. European journal of pharmacology, 1999, Feb-19, Volume: 367, Issue:2-3 Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; CHO Cells; Cricetinae; Cyclopropanes; Female; Humans; Imidazoles; In Vitro Techniques; Ligands; Phenoxypropanolamines; Protein Binding; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Trachea; Urea	1999
Molecular hashkeys: a novel method for molecular characterization and its application for predicting important pharmaceutical properties of molecules. Journal of medicinal chemistry, 1999, May-20, Volume: 42, Issue:10 Topics: Drug Design; Intestinal Absorption; Models, Molecular; Pharmaceutical Preparations; Structure-Activity Relationship	1999
Fast calculation of molecular polar surface area as a sum of fragment-based contributions and its application to the prediction of drug transport properties. Journal of medicinal chemistry, 2000, Oct-05, Volume: 43, Issue:20 Topics: Biological Availability; Biological Transport; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Reproducibility of Results	2000
Experimental and computational screening models for the prediction of intestinal drug absorption. Journal of medicinal chemistry, 2001, Jun-07, Volume: 44, Issue:12 Topics: Biological Transport; Carbon Radioisotopes; Cell Line; Cell Membrane; Cell Membrane Permeability; Ciprofloxacin; Computational Biology; Drug Design; Foscarnet; Humans; Hydrogen Bonding; Intestinal Absorption; Intestinal Mucosa; Lactulose; Mannitol; Models, Biological; Raffinose; Surface Properties; Tritium; Verapamil	2001
The selectivity of beta-adrenoceptor antagonists at the human beta1, beta2 and beta3 adrenoceptors. British journal of pharmacology, 2005, Volume: 144, Issue:3 Topics: Adrenergic beta-1 Receptor Agonists; Adrenergic beta-2 Receptor Agonists; Adrenergic beta-3 Receptor Agonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Algorithms; Animals; Cell Line; CHO Cells; Cricetinae; Dioxoles; Humans; Propanolamines; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Receptors, Adrenergic, beta-3	2005
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk). Journal of medicinal chemistry, 2005, May-05, Volume: 48, Issue:9 Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water	2005
QSAR study on permeability of hydrophobic compounds with artificial membranes. Bioorganic & medicinal chemistry, 2007, Jun-01, Volume: 15, Issue:11 Topics: Biological Transport; Caco-2 Cells; Drug Evaluation, Preclinical; Humans; Hydrophobic and Hydrophilic Interactions; Membranes, Artificial; Permeability; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship	2007
Air to lung partition coefficients for volatile organic compounds and blood to lung partition coefficients for volatile organic compounds and drugs. European journal of medicinal chemistry, 2008, Volume: 43, Issue:3 Topics: Air; Animals; Humans; Lung; Organic Chemicals; Probability; Rats; Tissue Distribution; Volatilization	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain. Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19 Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship	2009
Neural computational prediction of oral drug absorption based on CODES 2D descriptors. European journal of medicinal chemistry, 2010, Volume: 45, Issue:3 Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical	2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Importance of physicochemical properties for the design of new pesticides. Journal of agricultural and food chemistry, 2011, Apr-13, Volume: 59, Issue:7 Topics: Anabasine; Animals; Biological Availability; Cell Membrane Permeability; Chemical Phenomena; Drug Design; Humans; Imidazoles; Insecticides; Neonicotinoids; Nitro Compounds; Pesticides; Quantitative Structure-Activity Relationship; Receptors, Nicotinic	2011
QSAR-based permeability model for drug-like compounds. Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8 Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2011
Predicting phenolic acid absorption in Caco-2 cells: a theoretical permeability model and mechanistic study. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:2 Topics: Artificial Intelligence; Caco-2 Cells; Cell Membrane Permeability; Cinnamates; Enterocytes; Humans; Hydrophobic and Hydrophilic Interactions; Intestinal Absorption; Kinetics; Models, Biological; Molecular Conformation; Osmolar Concentration; Phenols	2012
Beta-adrenergic receptor blocking drugs in spontaneous hypertension. The American journal of medicine, 1976, Volume: 61, Issue:5 Topics: Adrenergic beta-Antagonists; Aging; Alprenolol; Animals; Blood Pressure; Hypertension; Male; Metoprolol; Oxprenolol; Pindolol; Practolol; Propanolamines; Propranolol; Pulse; Rats; Rats, Inbred Strains; Sodium Chloride; Sotalol; Stereoisomerism; Time Factors	1976
Long term beta-adrenergic blockade reduces tyrosine hydroxylase and dopamine beta-hydroxylase activities in sympathetic ganglia. Nature, 1977, May-19, Volume: 267, Issue:5608 Topics: Acebutolol; Adrenergic beta-Antagonists; Animals; Blood Pressure; Dopamine beta-Hydroxylase; Ganglia, Autonomic; Metoprolol; Neural Pathways; Practolol; Propranolol; Rabbits; Time Factors; Tyrosine 3-Monooxygenase	1977
Beta-Adrenoceptor studies. 4. Influence of albumin on in vitro beta-adrenoceptor blocking and antiarrhythmic properties of propranolol, pindolol, practolol and metoprolol. Naunyn-Schmiedeberg's archives of pharmacology, 1977, Volume: 298, Issue:1 Topics: Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Anti-Arrhythmia Agents; Guinea Pigs; Heart Rate; In Vitro Techniques; Isoproterenol; Male; Metoprolol; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Ouabain; Pindolol; Practolol; Propanolamines; Propranolol; Protein Binding; Serum Albumin, Bovine; Trachea	1977
Pindolol: a pharmacokinetic comparison with other beta-adrenoceptor blocking agents. Acta medica Scandinavica. Supplementum, 1977, Volume: 606 Topics: Adrenergic beta-Antagonists; Alprenolol; Biological Availability; Half-Life; Humans; Metoprolol; Oxprenolol; Pindolol; Practolol; Propranolol; Protein Binding; Sotalol; Timolol	1977
Blockade of isoprenaline-induced changes in plasma free fatty acids, immunoreactive insulin levels and plasma renin activity in healthy human subjects, by propranolol, pindolol, practolol, atenolol, metoprolol and acebutolol. British journal of clinical pharmacology, 1978, Volume: 5, Issue:1 Topics: Acebutolol; Adrenergic beta-Antagonists; Adult; Atenolol; Blood Pressure; Fatty Acids, Nonesterified; Heart Rate; Humans; Insulin; Isoproterenol; Male; Metoprolol; Pindolol; Practolol; Propranolol; Renin	1978
Comparison of the effects of nine beta-adrenergic blocking agents on intraocular pressure in rabbits. Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie. Albrecht von Graefe's archive for clinical and experimental ophthalmology, 1979, Mar-05, Volume: 210, Issue:1 Topics: Adrenergic beta-Antagonists; Animals; Atenolol; Drug Tolerance; Ethanolamines; Intraocular Pressure; Metoprolol; Oxprenolol; Pindolol; Practolol; Propranolol; Rabbits; Sotalol; Timolol	1979
Long-term haloperidol-treatment of mice: a change in beta-adrenergic receptor responsiveness. Journal of neural transmission, 1979, Volume: 44, Issue:3 Topics: Adrenergic beta-Antagonists; Animals; Butoxamine; Haloperidol; Male; Metoprolol; Mice; Motor Activity; Practolol; Propranolol; Receptors, Adrenergic; Receptors, Adrenergic, beta	1979
Plasma potassium and adrenergic system. Journal of endocrinological investigation, 1978, Volume: 1, Issue:3 Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; Diabetes Mellitus; Humans; Insulin; Metoprolol; Potassium; Practolol	1978
The effect of local anaesthetics on the thyrotropin receptor-adenylate cyclase system. Biochemical Society transactions, 1976, Volume: 4, Issue:1 Topics: Adenylyl Cyclases; Anesthetics, Local; Humans; Metoprolol; Polyphloretin Phosphate; Practolol; Propranolol; Quinidine; Receptors, Cell Surface; Thyroid Gland; Thyrotropin	1976
Presence of beta-adrenoreceptors in the hypothalamus; their importance for the pressor response to hypothalamic stimulation. Naunyn-Schmiedeberg's archives of pharmacology, 1977, Volume: 297, Issue:3 Topics: Animals; Blood Pressure; Catheterization; Cats; Drug Interactions; Electric Stimulation; Female; Hypothalamus; Isoproterenol; Male; Metoprolol; Practolol; Procaine; Propranolol; Receptors, Adrenergic; Receptors, Adrenergic, beta; Sotalol; Stereoisomerism; Tolazoline	1977
Hormone action at the membrane level. VI. Binding of (-)-[3H]dihydroalprenolol and (+/-)-[3H]isoproterenol to turkey erythrocytes and correlation with adenylate cyclase activity. Biochimica et biophysica acta, 1978, Feb-01, Volume: 538, Issue:3 Topics: Adenylyl Cyclases; Alprenolol; Animals; Binding Sites; Epinephrine; Erythrocyte Membrane; Erythrocytes; Ethanolamines; Female; Isoproterenol; Metoprolol; Norepinephrine; Practolol; Propranolol; Receptors, Adrenergic, beta; Stereoisomerism; Turkeys	1978
Broncho-and cardioselective beta-receptor active drugs in the treatment of asthmatic patients. Clinical studies of effects and side effects of terbutaline, practolol and metoprolol. Scandinavian journal of respiratory diseases. Supplementum, 1977, Volume: 97 Topics: Administration, Oral; Asthma; Bronchodilator Agents; Dose-Response Relationship, Drug; Drug Evaluation; Humans; Injections, Subcutaneous; Metoprolol; Muscle Cramp; Practolol; Propanolamines; Terbutaline; Tremor	1977
Effect of cardioselective beta-blockade by metoprolol on the phasic myocardial blood content and epi/endocardial ratio. Annals of clinical research, 1977, Volume: 9, Issue:2 Topics: Animals; Coronary Circulation; Guinea Pigs; Heart; Male; Metoprolol; Practolol; Propanolamines; Propranolol	1977
Beta adrenoceptors mediate the catecholamine-induced stimulation of oxytocin secretion from cultured bovine granulosa cells. Reproduction, fertility, and development, 1991, Volume: 3, Issue:6 Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; Animals; Cattle; Cells, Cultured; Dobutamine; Epinephrine; Female; Granulosa Cells; Metoprolol; Norepinephrine; Oxytocin; Phentolamine; Practolol; Propranolol; Receptors, Adrenergic, beta	1991
Effects of selective and non-selective beta 1-blockade on renin secretion in the isolated rat kidney. Revista espanola de fisiologia, 1989, Volume: 45, Issue:2 Topics: Adrenergic beta-Antagonists; Animals; Isoproterenol; Kidney; Male; Metoprolol; Practolol; Propranolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Renin; Secretory Rate; Species Specificity	1989
Beta adrenergic receptors in human cavernous tissue. The Journal of urology, 1985, Volume: 133, Issue:4 Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Binding Sites; Ethanolamines; Humans; Iodine Radioisotopes; Iodocyanopindolol; Male; Metoprolol; Penis; Pindolol; Practolol; Propanolamines; Propranolol; Receptors, Adrenergic, beta	1985
Prenalterol: a partial beta 1-adrenoceptor agonist or a beta-blocker with intrinsic activity? International journal of clinical pharmacology, therapy, and toxicology, 1985, Volume: 23, Issue:1 Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Adult; Blood Pressure; Dobutamine; Echocardiography; Electrocardiography; Heart Rate; Hemodynamics; Humans; Male; Metoprolol; Practolol; Prenalterol	1985
Beta adrenergic influence on esophageal and colonic motility in man. Scandinavian journal of gastroenterology. Supplement, 1985, Volume: 116 Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Adult; Colon; Colonic Diseases, Functional; Esophagus; Female; Gastrointestinal Motility; Humans; Male; Manometry; Metoprolol; Middle Aged; Parasympatholytics; Practolol; Prenalterol; Propranolol; Sincalide; Terbutaline	1985
Beta-adrenergic control of motility in the rat colon. I. Evidence for functional separation of the beta 1- and beta 2-adrenoceptor-mediated inhibition of colon activity. Gastroenterology, 1986, Volume: 90, Issue:2 Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Colon; Gastrointestinal Motility; Isoproterenol; Male; Metoprolol; Muscle, Smooth; Practolol; Prenalterol; Propanolamines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Sympathectomy; Terbutaline; Tetrodotoxin	1986
The effect of beta blockers on cardiac neural discharge associated with coronary occlusion in the cat. Journal of clinical pharmacology, 1987, Volume: 27, Issue:8 Topics: Adrenergic beta-Antagonists; Animals; Arrhythmias, Cardiac; Blood Pressure; Cats; Coronary Disease; Heart Rate; Metoprolol; Neurons; Practolol; Sympathetic Nervous System; Timolol	1987
High-dose prenalterol in beta-blockade intoxication. Acta medica Scandinavica, 1985, Volume: 218, Issue:5 Topics: Adult; Antidotes; Epinephrine; Female; Humans; Metoprolol; Practolol; Prenalterol	1985
Immediate haemodynamic effects of prenalterol, a new adrenergic beta-1-receptor agonist, in healthy volunteers. European journal of clinical pharmacology, 1980, Volume: 18, Issue:3 Topics: Adolescent; Adrenergic beta-Agonists; Adult; Drug Interactions; Electrocardiography; Hemodynamics; Humans; Metoprolol; Practolol; Prenalterol	1980
[Cholinergic antagonism by beta-blockers. I. Spectrum of interactions]. Bollettino della Societa italiana di biologia sperimentale, 1980, May-15, Volume: 56, Issue:9 Topics: Abdominal Muscles; Acetylcholine; Adrenergic beta-Antagonists; Animals; Guinea Pigs; Heart; Ileum; Isoproterenol; Labetalol; Male; Metoprolol; Pindolol; Practolol; Propranolol; Receptors, Cholinergic; Sotalol	1980
[Cholinergic antagonism by beta-blockers. II. Sequence of interactions and final steady state effects]. Bollettino della Societa italiana di biologia sperimentale, 1980, May-15, Volume: 56, Issue:9 Topics: Acetylcholine; Adrenergic beta-Antagonists; Animals; Drug Interactions; Guinea Pigs; Heart; Isoproterenol; Labetalol; Male; Metoprolol; Practolol; Propranolol; Receptors, Cholinergic; Time Factors	1980
[Use of beta-adrenergic blocking agents in acute myocardial infarction (author's transl)]. Herz, 1981, Volume: 6, Issue:2 Topics: Acute Disease; Adrenergic beta-Antagonists; Animals; Coronary Circulation; Creatine Kinase; Electrocardiography; Hemodynamics; Humans; Metoprolol; Myocardial Infarction; Practolol; Propranolol	1981
Characterization of [3H](+/-)carazolol binding to beta-adrenergic receptors. Application to study of beta-adrenergic receptor subtypes in canine ventricular myocardium and lung. Circulation research, 1981, Volume: 49, Issue:2 Topics: Adrenergic beta-Antagonists; Animals; Binding, Competitive; Carbazoles; Dogs; Kinetics; Lung; Membranes; Metoprolol; Myocardium; Practolol; Propanolamines	1981
Anticholinesterase effect of sotalol. The Indian journal of medical research, 1981, Volume: 73 Topics: Abdominal Muscles; Acetylcholine; Adrenergic beta-Antagonists; Animals; Carbachol; Cholinesterase Inhibitors; In Vitro Techniques; Metoprolol; Muscle Contraction; Physostigmine; Practolol; Propranolol; Ranidae; Sotalol	1981
Drug-induced localized systemic scleroses. Transactions of the American Clinical and Climatological Association, 1981, Volume: 92 Topics: Adrenergic beta-Antagonists; Humans; Methysergide; Metoprolol; Practolol; Propranolol; Scleroderma, Systemic	1981
Variability in the preventive action of the B-blockers on genetic hypertension in the rat. Paroi arterielle, 1980, Volume: 6, Issue:4 Topics: Acebutolol; Adrenergic beta-Antagonists; Alprenolol; Animals; Blood Pressure; Dose-Response Relationship, Drug; Hypertension; Male; Metoprolol; Oxprenolol; Pindolol; Practolol; Propranolol; Rats; Rats, Inbred Strains; Species Specificity; Time Factors	1980
Characterization of the beta-adrenergic inhibition of motility in cat colon strips. European journal of pharmacology, 1982, Jan-08, Volume: 77, Issue:1 Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Cats; Colon; Female; Gastrointestinal Motility; In Vitro Techniques; Isoproterenol; Male; Metoprolol; Practolol; Prenalterol; Propanolamines; Receptors, Adrenergic; Receptors, Adrenergic, beta; Terbutaline; Tetrodotoxin	1982
Effect of prenalterol, a beta-1-adrenoceptor agonist, on renin secretion rate in the anaesthetized dog. Acta pharmacologica et toxicologica, 1981, Volume: 49, Issue:3 Topics: Adrenergic beta-Agonists; Anesthesia; Animals; Denervation; Dogs; Female; Kidney; Male; Metoprolol; Practolol; Prenalterol; Renin; Secretory Rate	1981
Comparative investigation of the effects of metoprolol, propranolol, practolol, and verapamil in the acute phase of experimental myocardial infarction. Klinische Wochenschrift, 1982, Jan-15, Volume: 60, Issue:2 Topics: Adrenergic beta-Antagonists; Animals; Arrhythmias, Cardiac; Blood Pressure; Calcium Channel Blockers; Central Venous Pressure; Creatine Kinase; Hydrogen-Ion Concentration; Metoprolol; Myocardial Infarction; Practolol; Propanolamines; Propranolol; Rats; Verapamil	1982
Identification of the beta adrenergic receptor subtype on astroglia purified from rat brain. The Journal of pharmacology and experimental therapeutics, 1982, Volume: 222, Issue:3 Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Astrocytes; Astrocytoma; Cells, Cultured; Cerebral Cortex; Ethanolamines; Glioma; Lung; Metoprolol; Neuroglia; Pindolol; Practolol; Propanolamines; Rats; Receptors, Adrenergic; Receptors, Adrenergic, beta	1982
Electrophysiological studies with prenalterol. Acta medica Scandinavica. Supplementum, 1982, Volume: 659 Topics: Adrenergic beta-Agonists; Atrial Fibrillation; Atrioventricular Node; Bradycardia; Bundle of His; Cardiac Catheterization; Electrocardiography; Electrophysiology; Female; Heart; Heart Atria; Heart Block; Heart Conduction System; Heart Rate; Humans; Male; Metoprolol; Practolol; Prenalterol	1982
Clinical experiences with prenalterol as an antidote to Beta-adrenoceptor blockade. Acta medica Scandinavica. Supplementum, 1982, Volume: 659 Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Adult; Aged; Anesthesia; Cardiac Catheterization; Drug Interactions; Female; Humans; Hypertension; Hypotension; Male; Metoprolol; Myocardial Infarction; Practolol; Prenalterol; Propranolol	1982
Prenalterol as an antidote to massive doses of metoprolol--a cardiovascular study in the dog. Acta medica Scandinavica. Supplementum, 1982, Volume: 659 Topics: Adrenergic beta-Agonists; Animals; Blood Pressure; Cardiac Output; Central Venous Pressure; Dogs; Dose-Response Relationship, Drug; Electrocardiography; Female; Heart; Heart Rate; Infusions, Parenteral; Male; Metoprolol; Practolol; Prenalterol; Propanolamines; Pulmonary Wedge Pressure; Stroke Volume; Vascular Resistance	1982
Basic pharmacological properties of prenalterol. Acta medica Scandinavica. Supplementum, 1982, Volume: 659 Topics: Adrenergic beta-Agonists; Animals; Blood Pressure; Cats; Cyclic AMP; Dose-Response Relationship, Drug; Epinephrine; Guinea Pigs; Heart Rate; In Vitro Techniques; Isoproterenol; Metoprolol; Myocardial Contraction; Papillary Muscles; Phentolamine; Practolol; Prenalterol; Propanolamines; Rabbits; Receptors, Adrenergic, beta; Terbutaline; Vascular Resistance	1982
The importance of an intact sympathetic innervation for the differentiation of the beta-adrenoceptor subtypes in the rat parotid gland. Acta physiologica Scandinavica, 1982, Volume: 115, Issue:3 Topics: Adrenergic beta-Antagonists; Animals; Dihydroalprenolol; Ephedrine; Metoprolol; Parotid Gland; Practolol; Prenalterol; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Adrenergic, beta; Sympathectomy; Terbutaline	1982
Studies of catecholamine effect on cyclic AMP in human cultured thyroid cells: their interaction with thyrotrophin receptor. Acta endocrinologica, 1983, Volume: 102, Issue:1 Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Cells, Cultured; Cyclic AMP; DNA; Epinephrine; Humans; Isoproterenol; Metoprolol; Norepinephrine; Practolol; Prenalterol; Receptors, Cell Surface; Receptors, Thyrotropin; Terbutaline; Thyroid Gland; Thyrotropin	1983
Haemodynamic dose-response effects of intravenous beta-blocking drugs with different ancillary properties in patients with coronary heart disease. European heart journal, 1982, Volume: 3, Issue:6 Topics: Adrenergic beta-Antagonists; Adult; Blood Pressure; Cardiac Output; Coronary Disease; Dose-Response Relationship, Drug; Heart Rate; Hemodynamics; Humans; Injections, Intravenous; Male; Metoprolol; Middle Aged; Oxprenolol; Practolol; Propranolol; Pulmonary Wedge Pressure	1982
Absorption of beta-adrenoceptor antagonists to Amberlite resin. British journal of clinical pharmacology, 1983, Volume: 15, Issue:4 Topics: Adrenergic alpha-Antagonists; Adsorption; Alprenolol; Hemoperfusion; Humans; In Vitro Techniques; Ion Exchange Resins; Metoprolol; Practolol; Prenalterol	1983
Effects of beta 1-adrenoceptor stimulation and blockade studied in asthmatic airways. European journal of respiratory diseases. Supplement, 1984, Volume: 135 Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Asthma; Humans; Metoprolol; Practolol; Prenalterol; Propanolamines; Receptors, Adrenergic, beta; Tachycardia; Terbutaline	1984
Beta 1-adrenoceptor mediated salivary gland enlargement in the rat. Experientia, 1984, Aug-15, Volume: 40, Issue:8 Topics: Adrenergic beta-Agonists; Animals; Female; Metoprolol; Organ Size; Parotid Gland; Practolol; Prenalterol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Submandibular Gland; Terbutaline	1984
Influence of long-term beta receptor stimulation with prenalterol on intrinsic heart rate in rats. European journal of applied physiology and occupational physiology, 1984, Volume: 53, Issue:1 Topics: Adrenergic beta-Agonists; Animals; Cardiotonic Agents; Exercise Test; Female; Heart Rate; Isoproterenol; Metoprolol; Physical Exertion; Practolol; Prenalterol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Stimulation, Chemical	1984
Beta 1- and beta 2-adrenoceptor-mediated secretion of amylase from incubated rat parotid gland. Acta physiologica Scandinavica, 1984, Volume: 120, Issue:3 Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Amylases; Animals; Ephedrine; Female; Metoprolol; Norepinephrine; Parotid Gland; Practolol; Prenalterol; Propanolamines; Propranolol; Rats; Rats, Inbred Strains; Terbutaline	1984
Subtypes of beta-adrenergic receptors in rat cerebral microvessels. Brain research, 1981, Sep-07, Volume: 220, Issue:1 Topics: Animals; Binding, Competitive; Cerebrovascular Circulation; Ethanolamines; Kinetics; Metoprolol; Pindolol; Practolol; Rats; Receptors, Adrenergic; Receptors, Adrenergic, beta	1981
Subclasses of beta-adrenoceptors--a quantitative estimation of beta 1- and beta 2- adrenoceptors in guinea pig and human lung. Postgraduate medical journal, 1981, Volume: 57 Suppl 1 Topics: Aged; Animals; Atenolol; Betaxolol; Cell Membrane; Guinea Pigs; Humans; Iodocyanopindolol; Lung; Metoprolol; Middle Aged; Models, Biological; Pindolol; Practolol; Propanolamines; Receptors, Adrenergic; Receptors, Adrenergic, beta	1981
The role of beta- and alpha-adrenoceptors in the regulation of the stages of the sleep-waking cycle in the cat. Brain research, 1983, Oct-24, Volume: 277, Issue:1 Topics: Albuterol; Animals; Atenolol; Cats; Clonidine; Male; Metoprolol; Phentolamine; Practolol; Prazosin; Prenalterol; Propranolol; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Sleep Stages	1983
Beta adrenoreceptors in the rabbit bladder detrusor muscle. The Journal of pharmacology and experimental therapeutics, 1984, Volume: 228, Issue:2 Topics: Animals; Ethanolamines; Iodine Radioisotopes; Iodocyanopindolol; Male; Metoprolol; Muscle, Smooth; Pindolol; Practolol; Propanolamines; Propranolol; Rabbits; Receptors, Adrenergic, beta; Urinary Bladder	1984
Ventilatory and haemodynamic effects of beta 1-selective and beta 2-selective stimulation in asthmatic patients. European journal of respiratory diseases. Supplement, 1984, Volume: 135 Topics: Asthma; Blood Pressure; Heart Rate; Humans; Metoprolol; Practolol; Prenalterol; Receptors, Adrenergic, beta; Terbutaline	1984
Cardiac dysrhythmias during outpatient dental anaesthesia with enflurane. The role of "beta blockade". Acta anaesthesiologica Scandinavica, 1984, Volume: 28, Issue:5 Topics: Adolescent; Adult; Aged; Ambulatory Surgical Procedures; Anesthesia, Dental; Anesthesia, Inhalation; Arrhythmias, Cardiac; Electrocardiography; Enflurane; Female; Humans; Male; Metoprolol; Middle Aged; Practolol; Tachycardia	1984
Effects of practolol and metoprolol on QT interval, heart rate and arterial pressure during induction of anaesthesia. Acta anaesthesiologica Scandinavica, 1984, Volume: 28, Issue:6 Topics: Adult; Anesthesia, General; Blood Pressure; Electrocardiography; Female; Heart Rate; Hemodynamics; Humans; Male; Metoprolol; Middle Aged; Myocardial Contraction; Practolol; Preanesthetic Medication	1984
Massive metoprolol poisoning treated with prenalterol. Acta medica Scandinavica, 1983, Volume: 214, Issue:3 Topics: Adult; Dose-Response Relationship, Drug; Ethanol; Humans; Male; Metoprolol; Practolol; Prenalterol; Suicide, Attempted	1983
Effect of norepinephrine, prenalterol and metoprolol on the histochemical localization of adenylate cyclase activity in the brown adipose tissue of newborn rat. Histochemistry, 1982, Volume: 76, Issue:4 Topics: Adenylyl Cyclases; Adipose Tissue, Brown; Animals; Animals, Newborn; Histocytochemistry; Metoprolol; Norepinephrine; Practolol; Prenalterol; Propanolamines; Rats	1982
Central and peripheral haemodynamic effects of prenalterol in patients with coronary heart disease. Clinical physiology (Oxford, England), 1981, Volume: 1, Issue:5 Topics: Blood Pressure; Cardiac Output; Female; Forearm; Heart; Heart Rate; Hemodynamics; Humans; Injections, Intravenous; Male; Metoprolol; Middle Aged; Myocardial Infarction; Practolol; Prenalterol; Pulmonary Artery; Regional Blood Flow; Stroke Volume; Systole; Time Factors; Vascular Resistance	1981
Beta-receptor blockade in preventing sudden death. European heart journal, 1993, Volume: 14, Issue:5 Topics: Adrenergic beta-Antagonists; Atenolol; Death, Sudden, Cardiac; Humans; Metoprolol; Practolol; Sotalol; Ventricular Fibrillation	1993