pozanicline has been researched along with nicotine in 12 studies
| Studies (pozanicline) | Trials (pozanicline) | Recent Studies (post-2010) (pozanicline) | Studies (nicotine) | Trials (nicotine) | Recent Studies (post-2010) (nicotine) |
|---|---|---|---|---|---|
| 28 | 5 | 13 | 28,519 | 2,280 | 9,302 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (41.67) | 18.2507 |
| 2000's | 2 (16.67) | 29.6817 |
| 2010's | 4 (33.33) | 24.3611 |
| 2020's | 1 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Anderson, DJ; Arneric, SP; Brioni, JD; Buccafusco, JJ; Buckley, MJ; Decker, MW; Donnelly-Roberts, DL; Garvey, DS; Gunn, DE; Holladay, MW; Lin, NH; Marsh, KG; Prendergast, MA; Rodrigues, AD; Ryther, KB; Sullivan, JP; Williams, M | 1 |
| Dart, MJ; Holladay, MW; Lynch, JK | 1 |
| Efange, SM; Francesconi, L; Howell, RC; Kung, MP; Papke, RL; Rampersad, MV; Todaro, LJ; Tu, Z; von Hohenberg, K | 1 |
| Abraham, R; Bhyrapuneni, G; Bogaraju, N; Jasti, V; Mekala, VR; Mohammed, AR; Muddana, N; Nirogi, R; Palacharla, RC; Ravella, SR; Shinde, AK; Subramanian, R; Thentu, JB | 1 |
| Arneric, SP; Bannon, AW; Brioni, JD; Buccafusco, JJ; Curzon, P; Daanen, JF; Decker, MW; Gunther, KL; Holladay, MW; Jackson, WJ; Li, Y; Lin, NH; Prendergast, MA | 1 |
| Arneric, SP; Buccafusco, JJ; Decker, MW; Jackson, WJ; Prendergast, MA; Terry, AV | 1 |
| Arneric, SP; Briggs, CA; Gopalakrishnan, M; McKenna, DG; Monteggia, LM; Roch, JM; Sullivan, JP; Touma, E | 1 |
| Decker, MW; Man, K; Parikh, V; Sarter, M | 1 |
| Angelakos, CC; Meyer, PJ; Paolone, G; Robinson, TE; Sarter, M | 1 |
| Blendy, JA; Turner, JR; Yohn, NL | 1 |
| Arreola, AC; Kimmey, BA; Lee, AM; Schmidt, HD | 1 |
| Connor, DA; Gould, TJ; Yildirim, E | 1 |
1 review(s) available for pozanicline and nicotine
| Article | Year |
|---|---|
Neuronal nicotinic acetylcholine receptors as targets for drug discovery.
Topics: Acetylcholine; Animals; Binding Sites; Dopamine; Drug Design; Humans; Molecular Structure; Nervous System; Neurons; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Receptors, Nicotinic; Structure-Activity Relationship | 1997 |
11 other study(ies) available for pozanicline and nicotine
| Article | Year |
|---|---|
Structure-activity studies on 2-methyl-3-(2(S)-pyrrolidinylmethoxy) pyridine (ABT-089): an orally bioavailable 3-pyridyl ether nicotinic acetylcholine receptor ligand with cognition-enhancing properties.
Topics: Administration, Oral; Alkaloids; Animals; Anti-Anxiety Agents; Azocines; Biological Availability; Bungarotoxins; Cell Line; Cognition; Dogs; Haplorhini; Humans; Hypothermia; Isoxazoles; Ligands; Maze Learning; Mice; Molecular Structure; Psychomotor Performance; Pyrrolidines; Quinolizines; Receptors, Nicotinic; Rubidium; Structure-Activity Relationship | 1997 |
2-(2-Piperidyl)- and 2-(2-pyrrolidyl)chromans as nicotine agonists: synthesis and preliminary pharmacological characterization.
Topics: Acetylcholine; Animals; Cerebral Cortex; Chromans; Cloning, Molecular; Corpus Striatum; Crystallography, X-Ray; Dopamine; Humans; In Vitro Techniques; Nicotine; Nicotinic Agonists; Oocytes; Piperidines; Pyrrolidines; Radioligand Assay; Rats; Receptors, Nicotinic; Structure-Activity Relationship; Synaptosomes; Xenopus laevis | 2001 |
Discovery and Development of 3-(6-Chloropyridine-3-yloxymethyl)-2-azabicyclo[3.1.0]hexane Hydrochloride (SUVN-911): A Novel, Potent, Selective, and Orally Active Neuronal Nicotinic Acetylcholine α4β2 Receptor Antagonist for the Treatment of Depression.
Topics: Administration, Oral; Animals; Antidepressive Agents; Bridged Bicyclo Compounds; Depression; Halogenation; Humans; Male; Nicotinic Antagonists; Pyridines; Rats; Rats, Wistar; Receptors, Nicotinic | 2020 |
ABT-089 [2-methyl-3-(2-(S)-pyrrolidinylmethoxy)pyridine dihydrochloride]: II. A novel cholinergic channel modulator with effects on cognitive performance in rats and monkeys.
Topics: Animals; Avoidance Learning; Cholinergic Agents; Cognition; Discrimination Learning; Female; Ion Channels; Macaca nemestrina; Male; Maze Learning; Nicotine; Pyridines; Pyrrolidines; Rats; Receptors, Nicotinic | 1997 |
Central nicotinic receptor agonists ABT-418, ABT-089, and (-)-nicotine reduce distractibility in adult monkeys.
Topics: Animals; Anti-Anxiety Agents; Attention; Cholinergic Agents; Dose-Response Relationship, Drug; Female; Isoxazoles; Macaca mulatta; Macaca nemestrina; Male; Mental Recall; Nicotine; Nicotinic Agonists; Photic Stimulation; Pyridines; Pyrrolidines; Receptors, Nicotinic | 1998 |
Gain of function mutation of the alpha7 nicotinic receptor: distinct pharmacology of the human alpha7V274T variant.
Topics: Acetylcholine; Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Amino Acid Substitution; Animals; Atropine; Choline; Dihydro-beta-Erythroidine; Dimethylphenylpiperazinium Iodide; Dose-Response Relationship, Drug; Genetic Variation; Humans; Lobeline; Mecamylamine; Membrane Potentials; Muscarinic Antagonists; Mutation; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Oocytes; Pyridines; Pyrrolidines; Receptors, Nicotinic; Threonine; Tubocurarine; Valine; Xenopus | 1999 |
Glutamatergic contributions to nicotinic acetylcholine receptor agonist-evoked cholinergic transients in the prefrontal cortex.
Topics: Acetylcholine; Analysis of Variance; Animals; Choline; Dihydro-beta-Erythroidine; Dose-Response Relationship, Drug; Electrochemistry; Evoked Potentials; Excitatory Amino Acid Antagonists; Glutamic Acid; In Vitro Techniques; Male; Mecamylamine; Neostigmine; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Prefrontal Cortex; Pyridines; Pyrrolidines; Quinoxalines; Rats; Sodium Channel Blockers; Tetrodotoxin; Valine | 2008 |
Cholinergic control over attention in rats prone to attribute incentive salience to reward cues.
Topics: Acetylcholine; Amphetamine; Animals; Attention; Cholinergic Agonists; Conditioning, Classical; Cues; Dopamine Uptake Inhibitors; Female; Male; Microdialysis; Motivation; Nicotine; Principal Component Analysis; Pyridines; Pyrrolidines; Rats; Rats, Sprague-Dawley; Reward; Time Factors; Video Recording | 2013 |
Activation of α4β2*/α6β2* nicotinic receptors alleviates anxiety during nicotine withdrawal without upregulating nicotinic receptors.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Brain; Drug Partial Agonism; Indoles; Male; Mice; Nicotine; Nicotinic Agonists; Pyridines; Pyrrolidines; Quinuclidines; Radioligand Assay; Receptors, Nicotinic; Substance Withdrawal Syndrome; Time Factors; Up-Regulation | 2014 |
Administration of the nicotinic acetylcholine receptor agonists ABT-089 and ABT-107 attenuates the reinstatement of nicotine-seeking behavior in rats.
Topics: Analysis of Variance; Animals; Conditioning, Operant; Dose-Response Relationship, Drug; Drug-Seeking Behavior; Indoles; Male; Nicotine; Nicotinic Agonists; Pyridines; Pyrrolidines; Quinuclidines; Rats; Rats, Sprague-Dawley; Reinforcement Schedule; Reward; Self Administration; Sucrose | 2014 |
ABT-089, but not ABT-107, ameliorates nicotine withdrawal-induced cognitive deficits in C57BL6/J mice.
Topics: Animals; Cognition; Conditioning, Psychological; Cues; Dose-Response Relationship, Drug; Drug Partial Agonism; Fear; Hippocampus; Indoles; Learning; Male; Mice; Mice, Inbred C57BL; Nicotine; Nicotinic Agonists; Pyridines; Pyrrolidines; Quinuclidines; Receptors, Nicotinic; Substance Withdrawal Syndrome; Tobacco Use Disorder | 2015 |