Page last updated: 2024-09-03

pozanicline and cytisine

pozanicline has been researched along with cytisine in 3 studies

Compound Research Comparison

Studies (pozanicline)	Trials (pozanicline)	Recent Studies (post-2010) (pozanicline)	Studies (cytisine)	Trials (cytisine)	Recent Studies (post-2010) (cytisine)
28	5	13	519	19	178

Protein Interaction Comparison

Protein	Taxonomy	cytisine (IC50)
Neuronal acetylcholine receptor subunit alpha-4	Rattus norvegicus (Norway rat)	0.0692
Neuronal acetylcholine receptor subunit beta-2	Rattus norvegicus (Norway rat)	0.0692
Neuronal acetylcholine receptor subunit beta-2	Homo sapiens (human)	0.05
Neuronal acetylcholine receptor subunit alpha-4	Homo sapiens (human)	0.05

Research

Studies (3)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	2 (66.67)	18.2507
2000's	1 (33.33)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Dart, MJ; Holladay, MW; Lynch, JK	1
Efange, SM; Francesconi, L; Howell, RC; Kung, MP; Papke, RL; Rampersad, MV; Todaro, LJ; Tu, Z; von Hohenberg, K	1
Anderson, DJ; Arneric, SP; Briggs, CA; Campbell, JE; Donnelly-Roberts, D; Gopalakrishnan, M; Gunn, DE; He, Y; Holladay, MW; Lin, NH; McKenna, DG; Molinari, E; Piattoni-Kaplan, M; Ryther, KB; Sullivan, JP; Williams, M; Wonnacott, S; Xue, IC	1

Reviews

1 review(s) available for pozanicline and cytisine

Article	Year
Neuronal nicotinic acetylcholine receptors as targets for drug discovery. Journal of medicinal chemistry, 1997, Dec-19, Volume: 40, Issue:26 Topics: Acetylcholine; Animals; Binding Sites; Dopamine; Drug Design; Humans; Molecular Structure; Nervous System; Neurons; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Receptors, Nicotinic; Structure-Activity Relationship	1997

Other Studies

2 other study(ies) available for pozanicline and cytisine

Article	Year
2-(2-Piperidyl)- and 2-(2-pyrrolidyl)chromans as nicotine agonists: synthesis and preliminary pharmacological characterization. Journal of medicinal chemistry, 2001, Dec-20, Volume: 44, Issue:26 Topics: Acetylcholine; Animals; Cerebral Cortex; Chromans; Cloning, Molecular; Corpus Striatum; Crystallography, X-Ray; Dopamine; Humans; In Vitro Techniques; Nicotine; Nicotinic Agonists; Oocytes; Piperidines; Pyrrolidines; Radioligand Assay; Rats; Receptors, Nicotinic; Structure-Activity Relationship; Synaptosomes; Xenopus laevis	2001
ABT-089 [2-methyl-3-(2-(S)-pyrrolidinylmethoxy)pyridine]: I. A potent and selective cholinergic channel modulator with neuroprotective properties. The Journal of pharmacology and experimental therapeutics, 1997, Volume: 283, Issue:1 Topics: Acetylcholine; Alkaloids; Animals; Azocines; Cholinergic Agents; Dopamine; Humans; Ion Channels; Male; Mice; Neuroprotective Agents; Pyridines; Pyrrolidines; Quinolizines; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Rubidium Radioisotopes; Xenopus laevis	1997

Article

Year

2-(2-Piperidyl)- and 2-(2-pyrrolidyl)chromans as nicotine agonists: synthesis and preliminary pharmacological characterization.

Journal of medicinal chemistry, 2001, Dec-20, Volume: 44, Issue:26

Topics: Acetylcholine; Animals; Cerebral Cortex; Chromans; Cloning, Molecular; Corpus Striatum; Crystallography, X-Ray; Dopamine; Humans; In Vitro Techniques; Nicotine; Nicotinic Agonists; Oocytes; Piperidines; Pyrrolidines; Radioligand Assay; Rats; Receptors, Nicotinic; Structure-Activity Relationship; Synaptosomes; Xenopus laevis

2001

ABT-089 [2-methyl-3-(2-(S)-pyrrolidinylmethoxy)pyridine]: I. A potent and selective cholinergic channel modulator with neuroprotective properties.

The Journal of pharmacology and experimental therapeutics, 1997, Volume: 283, Issue:1

Topics: Acetylcholine; Alkaloids; Animals; Azocines; Cholinergic Agents; Dopamine; Humans; Ion Channels; Male; Mice; Neuroprotective Agents; Pyridines; Pyrrolidines; Quinolizines; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Rubidium Radioisotopes; Xenopus laevis

1997