pozanicline and choline
pozanicline has been researched along with choline in 2 studies
*Choline: A basic constituent of lecithin that is found in many plants and animal organs. It is important as a precursor of acetylcholine, as a methyl donor in various metabolic processes, and in lipid metabolism. [MeSH]
*Choline: A basic constituent of lecithin that is found in many plants and animal organs. It is important as a precursor of acetylcholine, as a methyl donor in various metabolic processes, and in lipid metabolism. [MeSH]
Compound Research Comparison
| Studies (pozanicline) | Trials (pozanicline) | Recent Studies (post-2010) (pozanicline) | Studies (choline) | Trials (choline) | Recent Studies (post-2010) (choline) |
|---|---|---|---|---|---|
| 28 | 5 | 13 | 19,628 | 608 | 4,345 |
Protein Interaction Comparison
| Protein | Taxonomy | pozanicline (IC50) | choline (IC50) |
|---|---|---|---|
| Sodium- and chloride-dependent creatine transporter 1 | Rattus norvegicus (Norway rat) | 1.6 | |
| High affinity choline transporter 1 | Mus musculus (house mouse) | 1.6 |
Research
Studies (2)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Arneric, SP; Briggs, CA; Gopalakrishnan, M; McKenna, DG; Monteggia, LM; Roch, JM; Sullivan, JP; Touma, E | 1 |
| Decker, MW; Man, K; Parikh, V; Sarter, M | 1 |
Other Studies
2 other study(ies) available for pozanicline and choline
| Article | Year |
|---|---|
Gain of function mutation of the alpha7 nicotinic receptor: distinct pharmacology of the human alpha7V274T variant.
Topics: Acetylcholine; Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Amino Acid Substitution; Animals; Atropine; Choline; Dihydro-beta-Erythroidine; Dimethylphenylpiperazinium Iodide; Dose-Response Relationship, Drug; Genetic Variation; Humans; Lobeline; Mecamylamine; Membrane Potentials; Muscarinic Antagonists; Mutation; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Oocytes; Pyridines; Pyrrolidines; Receptors, Nicotinic; Threonine; Tubocurarine; Valine; Xenopus | 1999 |
Glutamatergic contributions to nicotinic acetylcholine receptor agonist-evoked cholinergic transients in the prefrontal cortex.
Topics: Acetylcholine; Analysis of Variance; Animals; Choline; Dihydro-beta-Erythroidine; Dose-Response Relationship, Drug; Electrochemistry; Evoked Potentials; Excitatory Amino Acid Antagonists; Glutamic Acid; In Vitro Techniques; Male; Mecamylamine; Neostigmine; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Prefrontal Cortex; Pyridines; Pyrrolidines; Quinoxalines; Rats; Sodium Channel Blockers; Tetrodotoxin; Valine | 2008 |