povidone-iodine and tetrachlorodecaoxide

In a controlled study on the treatment of wound-healing impairments 29 patients underwent local treatment with TCDO (Oxoferin) while Beta-isodona was used in 31 cases. Regarding the criterion of reducing the wound area, i.e. epithelization, a highly significant superiority of Oxoferin could be demonstrated in the treatment of complicated wounds. The evaluation of the state of granulation, that was documented by a semiquantitative procedure, indicated that Oxoferin tends to be slightly superior. However, the following observations have to be emphasized: Oxoferin induces a development of granulation tissue on exposed tendons, bones, and fasciae and the granular tissue is of much better quality than after treatment with Betaisodona. Concerning its effect on the degree of contamination, Oxoferin proved to be at least as efficacious as the established and effective antiseptic Betaisodona. Both substances are tolerated well and the application is simple, they do not differ here.

Topics: Adolescent; Adult; Aged; Chlorine; Clinical Trials as Topic; Epithelium; Female; Granulation Tissue; Humans; Male; Middle Aged; Oxides; Povidone; Povidone-Iodine; Random Allocation; Surgical Wound Infection; Wound Healing; Wound Infection