potassium chloride has been researched along with bay-k-8644 in 171 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 38 (22.22) | 18.7374 |
| 1990's | 89 (52.05) | 18.2507 |
| 2000's | 30 (17.54) | 29.6817 |
| 2010's | 13 (7.60) | 24.3611 |
| 2020's | 1 (0.58) | 2.80 |
| Authors | Studies |
|---|---|
| Aleixandre, A; Pintado, A; Puerro, M | 1 |
| Balfagón, G; de Sagarra, MR; Encabo, A; Ferrer, M; Marín, J; Peiró, C; Redondo, J | 1 |
| Bourreau, JP; Daniel, EE; Kwan, CY; Shimamoto, H | 1 |
| Lattanzio, FA; Ratz, PH | 1 |
| Barnett, DW; Falke, LC; Gillis, KD; Misler, S; Pressel, DM; Scharp, DW | 1 |
| Bollen, BA; McKlveen, RE; Stevenson, JA | 1 |
| Huang, TF; Ko, FN; Su, MJ; Teng, CM; Wang, ML; Wu, TS; Yu, SM | 1 |
| Abiko, Y; Ichihara, K; Nasa, Y; Yoshida, R | 1 |
| Cantabrana, B; Fernandez, AI; Hidalgo, A; Martinez, V | 1 |
| Storm, DS; Stuenkel, EL; Webb, RC | 1 |
| Grover, GJ; McCullough, JR; Ogletree, ML; Sargent, CA; Vesterqvist, O | 1 |
| Bishopric, NH; Sato, B; Webster, KA | 1 |
| Calixto, JB; Sant'ana, AE | 1 |
| Benishin, CG; Karpinski, E; Pang, PK; Shan, J; Wang, R | 1 |
| Cuccaro, ML; Jacobs, LS; Lorenson, MY | 1 |
| Gainullin, R; Saxon, M | 1 |
| Gomi, Y; Suzuki, N | 1 |
| Carrier, GO; White, RE | 1 |
| Abiru, T; Kamata, K; Kasuya, Y; Miyata, N | 1 |
| Bruner, CA; Webb, RC | 1 |
| Andre, P; Andriantsitohaina, R; Stoclet, JC | 1 |
| Calixto, JB; Rae, GA | 1 |
| Rembold, CM | 1 |
| Advenier, C; Cortijo, J; Esplugues, J; Morcillo, E; Naline, E; Sarriá, B | 1 |
| Biguad, M; Julou-Schaeffer, G; Parratt, JR; Stoclet, JC | 1 |
| Kakishita, E; Sakamoto, K; Wakabayashi, I | 1 |
| Liepins, A; McWilliam, TM; Rankin, AJ | 1 |
| Olson, KG; Welch, SP | 1 |
| Karaki, H; Kodama, I; Kown, SC; Kurahashi, K; Morikawa, M; Satake, N; Sawada, T; Shibata, S | 1 |
| Henstenberg, JD; Sharp, GW; Stafford, GA; Weiland, GA; Yaney, GC | 1 |
| Cantabrana, B; Hidalgo, A; Pérez Vallina, JR | 1 |
| Hatake, K; Masui, H; Sakamoto, K; Wakabayashi, I; Yoshimoto, S | 1 |
| Daly, CJ; Dunn, WR; McGrath, JC; Wilson, VG | 1 |
| Black, IB; DiCicco-Bloom, E; Pincus, DW | 1 |
| Wright, G | 1 |
| Akimoto, T; Ariyoshi, S; Fujisue, T; Ichida, S; Wada, T | 1 |
| Chang, KJ; Collins, MA; Xu, SF | 1 |
| Homma, I; Inazu, M; Sakai, Y | 1 |
| Cheung, DW | 1 |
| Allen, SL; Foster, RW; Small, RC; Towart, R | 1 |
| Carboni, E; Costa, E; Wojcik, WJ | 1 |
| Aizawa, T; Enyeart, JJ; Hinkle, PM | 1 |
| Assayag, E; Heisler, S; Labrie, F; Mehri, Y; Simard, J | 1 |
| Babich, M; Piascik, MT | 1 |
| Aoki, K; Asano, M | 1 |
| Advenier, C; Naline, E; Renier, A | 1 |
| Leslie, SW; Woodward, JJ | 1 |
| Nishimura, S; Sorimachi, M; Yano, K | 1 |
| Luchowski, EM; Rutledge, A; Su, CM; Triggle, DJ; Wei, XY | 1 |
| Armour, CL; Black, JL; Johnson, PR; Marthan, R | 2 |
| Churchill, MC; Churchill, PC | 1 |
| Moreland, RS; Moreland, S | 2 |
| Bräutigam, M; Herken, H; Kittner, B | 1 |
| Kato, H; Takata, Y | 1 |
| Dong, Y; Wadsworth, RM | 1 |
| Pang, PK; Sham, JS; Yang, MC | 1 |
| Noronha-Blob, L; Richard, C; U'Prichard, DC | 1 |
| Warbanow, W; Will-Shahab, L | 1 |
| Kimball, SD; Moreland, RS; Moreland, S; Powell, JR; Ushay, MP | 1 |
| Cook, ME; Leslie, SW; Woodward, JJ | 1 |
| Amore, B; Churchill, P; Ellis, V; Rossi, N | 1 |
| Fontaine, J; Lebrun, P | 1 |
| Andriantsitohaina, R; Stoclet, JC | 1 |
| Ito, M; Morikawa, M; Satake, N; Shibata, S | 1 |
| Kashiwabara, T; Nakayama, K; Tanaka, Y; Yamada, S | 1 |
| O'Donnell, SR; Wanstall, JC | 1 |
| Bowmer, CJ; Douglas, SA; Yates, MS | 1 |
| De Young, MB; Scarpa, A | 1 |
| Bevan, JA; Dowd, AL; Germann, P; Laher, I | 1 |
| Barbanti, G; Giachetti, A; Giuliani, S; Maggi, CA; Meli, A; Patacchini, R; Turini, D | 1 |
| Catt, KJ; Izumi, S; Stojilković, SS | 1 |
| Goto, K; Ishikawa, T; Kasuya, Y; Kimura, S; Masaki, T; Yanagisawa, M | 1 |
| Abe, K; Matsuki, N; Saito, H | 1 |
| Hof, A; Hof, RP; Loutzenhiser, R; Rüegg, UT | 1 |
| Cheung, CW; Gigg, M; Hartley, SA; Jones, LM; Usowicz, MM | 1 |
| Brochu, M; Roy, B; Sicotte, B; St-Louis, J | 1 |
| Abbe, R; Appel, SH; Bostwick, JR | 1 |
| Hill, MA; Liu, J; Meininger, GA | 1 |
| Shi, CZ; Wu, X; Wu, XD | 1 |
| Cherington, V; Riseberg, JC; Tischler, AS | 1 |
| Orth, DN; Won, JG | 1 |
| Codazzi, F; D'Andrea, P; Grohovaz, F; Meldolesi, J; Zacchetti, D | 1 |
| Furukawa, T; Katsuragi, T; Matsuo, K; Ogawa, S | 1 |
| Homma, I; Inazu, M; Sakai, Y; Shamoto, A; Zhu, B | 1 |
| Croxton, TL; Farley, LS; Hirshman, CA; Vannier, C | 1 |
| Freij, M; Kim, J; Phillippe, M; Saunders, T | 1 |
| Finta, KM; Lloyd, MC; Storm, DS; Watts, SW; Webb, RC | 1 |
| Calissano, P; Galli, C; Meucci, O; Schettini, G; Scorziello, A; Werge, TM | 1 |
| Miras-Portugal, MT; Rodriguez-Pascual, F; Torres, M | 1 |
| Abebe, W; Harris, KH; MacLeod, KM | 1 |
| Kataoka, Y; Kohzuma, M; Koizumi, S; Niwa, M; Shibaguchi, H; Shigematsu, K; Taniyama, K | 1 |
| Giuliani, S; Maggi, CA | 1 |
| Phillippe, M | 1 |
| Kato, T; Kondo, A; Saito, M | 1 |
| Dohi, T; Miyasako, T; Morita, K; Suemitsu, T; Uchiyama, Y | 1 |
| Fukata, F; Kanda, M; Kurahashi, K; Matsui, H; Nakamura, S; Shirahase, H; Wada, K | 1 |
| Brito, G; Bustamante, S; Morales, MA; Paeile, C; Ponce, H; Silva, A | 1 |
| Cantabrana, B; Fernández, AI; García de Boto, MJ; Gutiérrez, M; Hidalgo, A | 1 |
| Denborough, MA; Foster, PS | 1 |
| Akimoto, T; Ichida, S; Kishino, H; Matsuda, N; Nakazaki, S; Wada, T | 1 |
| Haymes, AA; Hinkle, PM | 1 |
| Hurst, RD; McDermott, GF; Whiteside, CI | 1 |
| Aleixandre, MA; King, AP; Puerro, M | 1 |
| Fontela, T; Garcia-Hermida, O; Marco, J; Rodriguez-Gallardo, J; Salas, M; Silvestre, RA | 1 |
| Dong, JM; Lim, L | 1 |
| Akishita, M; Han, SZ; Kim, S; Kozaki, K; Orimo, H; Ouchi, Y; Toba, K | 1 |
| Bell, GI; Dukes, ID; Philipson, LH; Polonsky, KS; Roe, MW; Sturis, J; Tang, J; Tokuyama, Y; Worley, JF | 1 |
| Guerrier, P; Leclerc, C; Moreau, M | 1 |
| Dave, JR; Doctor, BP; Koenig, ML; Ved, HS | 1 |
| Fujita, H; Kageyama, M; Nakata, K; Shirasawa, E | 1 |
| Eusebi, F; Giovannelli, A; Lorenzon, P; Ragozzino, D; Ruzzier, F | 1 |
| Haisenleder, DJ; Marshall, JC; Yasin, M | 1 |
| Morgan, CW; Ratz, PH; Shenfeld, OZ | 1 |
| Drucker-Colín, R; García, DE; Morales-Orozco, C; Morgado-Valle, C; Verdugo-Díaz, L | 1 |
| Brosenitsch, TA; Katz, DM; Kunze, DL; Salgado-Commissariat, D | 1 |
| Chik, CL; Ho, AK; Negishi, T | 2 |
| Held, B; Pearson, HA; Pocock, JM | 1 |
| Baker, H; Cigola, E; Franzen, L; Lee, JW; Volpe, BT | 1 |
| Goud, C; Pitt, B; Richey, JM; Webb, RC | 1 |
| Eatman, D; Rutecki, GW; Stallone, JN; Whittier, FC | 1 |
| Itoh, Y; Kimura, K; Oka, M; Ukai, Y | 1 |
| Gorr, SU; Moore, YR | 1 |
| Zhang, JT; Zhang, QZ | 1 |
| Chik, CL; Ho, AK; Karpinski, E; Li, B; Negishi, T | 1 |
| Campbell, WB; Geiger, J; Li, PL; Zou, AP | 1 |
| Sarna, SK; Shi, XZ | 1 |
| Amano, K; Andoh, T; Kuraishi, Y; Nakaoka, R; Tabuchi, A; Tsuda, M; Yukimine, M | 1 |
| Chida, K; Ichiyama, A; Kanai, M; Nakamura, H; Oki, Y; Suda, T; Uchida, C; Xue, HH; Zhao, DM | 1 |
| Cormier, R; Covey, DF; Fu, T; Isenberg, KE; Mennerick, S; Xu, W; Zorumski, CF | 1 |
| Brochu, M; Picard, S; Simaan, M; St-Louis, J | 1 |
| Ghisdal, P; Gomez, JP; Morel, N | 1 |
| Betancourt-Calle, S; Bollag, WB; Calle, RA; Isales, CM; Rasmussen, H; White, S | 1 |
| Higo, A; Katsura, M; Mohri, Y; Ohkuma, S; Shirotani, K; Shuto, K; Takesue, M; Tarumi, C | 1 |
| Bendhack, LM; Callera, GE; Varanda, WA | 1 |
| Aylor, KW; Burger, LL; Dalkin, AC; Haisenleder, DJ; Marshall, JC; Workman, LJ | 1 |
| Amano, T; Hai-Du, Y; Katsura, M; Mohri, Y; Ohkuma, S; Sasa, M; Shuto, K; Tsujimura, A | 1 |
| Koizumi, N; Masui, H; Siogawa, K; Wakabayashi, I | 1 |
| Bonnet, P; Bonnet, S; Ludwig, LM; Pratt, PF; Rusch, NJ | 1 |
| Barker, JL; Maric, D; Smith, SV; Sukhareva, M | 1 |
| Granger, JP; Herrington, JN; Khalil, RA; Murphy, JG | 1 |
| Cook, DI; Palma, CA; Poronnik, P; Tabiin, MT; Tuch, BE; Weinhaus, AJ | 1 |
| Hagiwara, K; Iijima, T; Miyoshi, I; Murakami, M; Murata, A; Nakagawasai, O; Tadano, T; Tan-No, K; Yamadera, F; Yanagisawa, T | 1 |
| Kadioglu, M; Kalyoncu, NI; Kesim, M; Ozyavuz, R; Ulku, C; Yaris, E | 1 |
| Jang, SJ; Koh, YY; Lim, DY | 1 |
| Cho, JW; Kang, BS; Kim, CY; Kim, IK; Kim, YH; Park, TG | 1 |
| Antunes, E; Corrado, AP; De Nucci, G; Teixeira, CE | 1 |
| Bowles, DK; McDonald, OG; Owens, GK; Sinha, S; Somlyo, AP; Somlyo, AV; Wamhoff, BR | 1 |
| August, A; Ben-Jebria, A; Ferrara, TJ | 1 |
| Dhalla, NS; Saini, HK | 1 |
| Díaz, M; García Marrero, B; Gómez, T; Marrero-Alonso, J | 1 |
| Kim, S; Nah, SY; Rhim, H | 1 |
| Du, L; Shen, J; Wang, W; Wang, Z; Xing, D; Yip, S | 1 |
| Chiang, W; Hsia, SM; Kuo, YH; Wang, PS | 1 |
| Blanck, TJ; Montoya-Gacharna, J; Neubert, TA; Recio-Pinto, E; Sutachan, JJ; Xu, CF; Xu, F; Zhang, J | 1 |
| An Haack, K; Bennett, MJ; Li, H; Narayan, SB; Tan, L; Warnock, A | 1 |
| Han, JH; Kim, TH; Lee, MY; Lee, SY; Moon, YT; Myung, SC; Park, SH | 1 |
| Bryan, RM; Crossland, RF; Hartley, CJ; Lloyd, EE; Marrelli, SP; Phillips, SC; Reddy, AK; Taffet, GE | 1 |
| Arcanjo, DD; Cavalcanti, SC; Oliveira, AP; Oliveira, NN; Oliveira, Rde C; Quintans-Júnior, LJ; Santos, MR; Silva-Filho, JC | 1 |
| Alustau, MC; Barbosa-Filho, JM; Braga, VA; Figueiredo, CS; Furtado, FF; Machado, NT; Medeiros, IA; Miranda, GEC; Oliveira-Filho, AA; Queiroz, TM | 1 |
| Cao, YX; Zhang, LX; Zhang, SQ | 1 |
| Gajdus, M; Grzesk, G; Malinowski, B; Szadujkis-Szadurska, K; Szadujkis-Szadurski, L; Wicinski, M | 1 |
| Arcanjo, DD; Chaves, MH; da Silva-Filho, JC; de Oliveira, AP; Ferreira-Filho, ES; Moura, LH; Oliveira, Rde C; Paulino, ET; Ribeiro, EA | 1 |
| Aceves, J; Caballero-Florán, I; Erlij, D; Florán, B; Ochoa-Sánchez, N; Paz-Bermúdez, F; Recillas-Morales, S; Sánchez-Vega, L; Silva, I | 1 |
| Di, F; Huang, J; Li, P; Zhai, H | 1 |
| Cavalcante, Fde A; Correia, AC; da Silva, BA; de Souza, IL; Paredes-Gamero, EJ; Santos, BV; Silva, Mda C; Vasconcelos, LH | 1 |
| Rustenbeck, I; Seemann, N; Welling, A | 1 |
| Borysova, L; Burdyga, T; Dora, KA; Garland, CJ | 1 |
| Alotaibi, MF | 1 |
171 other study(ies) available for potassium chloride and bay-k-8644
| Article | Year |
|---|---|
Alpha 2-adrenoceptor-mediated contractions in the rabbit aorta treated with BAY K 8644.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Aorta; Azepines; Calcium; Calcium Channels; In Vitro Techniques; Potassium Chloride; Prazosin; Rabbits; Receptors, Adrenergic, alpha; Vasoconstriction | 1992 |
Comparison of the vasoconstrictor responses induced by endothelin and phorbol 12,13-dibutyrate in bovine cerebral arteries.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Cattle; Cerebral Arteries; Cytosol; Electric Stimulation; Endothelins; Enzyme Activation; Membranes; Nifedipine; Phorbol 12,13-Dibutyrate; Potassium Chloride; Protein Kinase C; Serotonin; Vasoconstriction | 1992 |
Amplification of alpha adrenergic vasoconstriction in canine isolated mesenteric artery and vein.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenergic alpha-Agonists; Animals; Brimonidine Tartrate; Calcium; Dogs; Dose-Response Relationship, Drug; Endothelins; Female; In Vitro Techniques; Male; Mesenteric Arteries; Mesenteric Veins; Potassium Chloride; Prazosin; Quinoxalines; Receptors, Adrenergic, alpha; Vasoconstriction | 1992 |
L-type Ca2+ channel desensitization by F- reduces PhE-induced increase in [Ca2+]i but not stress.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channels; Deferoxamine; Dinoprost; Female; Femoral Artery; Fluorides; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Phenylephrine; Potassium Chloride; Rabbits; Stress, Mechanical; Time Factors | 1992 |
Stimulus-secretion coupling in beta-cells of transplantable human islets of Langerhans. Evidence for a critical role for Ca2+ entry.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Action Potentials; Azides; Calcium; Cytosol; Electrophysiology; Glucose; Humans; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Islets of Langerhans Transplantation; Kinetics; Membrane Potentials; Nifedipine; Potassium Chloride; Sodium Azide; Time Factors; Tolbutamide | 1992 |
Halothane relaxes preconstricted small and medium isolated porcine coronary artery segments more than isoflurane.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Coronary Vessels; Halothane; In Vitro Techniques; Isoflurane; Kinetics; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Potassium Chloride; Swine; Time Factors | 1992 |
Vasorelaxing effect in rat thoracic aorta caused by fraxinellone and dictamine isolated from the Chinese herb Dictamnus dasycarpus Turcz: comparison with cromakalim and Ca2+ channel blockers.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Alkaloids; Animals; Aorta, Thoracic; Benzofurans; Benzopyrans; Calcium; Calcium Channel Blockers; Cromakalim; Cyclic AMP; Cyclic GMP; Drugs, Chinese Herbal; Female; Glyburide; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Norepinephrine; Potassium Channels; Potassium Chloride; Pyrroles; Quinolines; Rats; Rats, Inbred Strains; Verapamil | 1992 |
Positive inotropic and negative chronotropic effects of (-)-cis-diltiazem in rat isolated atria.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenergic alpha-Antagonists; Animals; Aorta, Thoracic; Atenolol; Calcium; Diltiazem; Endothelium, Vascular; Guinea Pigs; Heart Atria; Heart Rate; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Myocardial Contraction; Potassium Chloride; Quinazolines; Rats; Rats, Inbred Strains; Stereoisomerism; Verapamil | 1992 |
Differential effect of calcium and Bay K 8644 on the inhibitory action of estrogens in the rat uterus.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Chloride; Diethylstilbestrol; Estradiol; Estrogen Antagonists; Estrogens; Female; In Vitro Techniques; Potassium Chloride; Propranolol; Rats; Rats, Inbred Strains; Uterine Contraction; Uterus | 1992 |
Calcium channel activation in arterioles from genetically hypertensive rats.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Arterioles; Calcium; Calcium Channels; Female; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Norepinephrine; Osmolar Concentration; Phentolamine; Potassium Chloride; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sodium | 1992 |
Effect of the phospholipase A2 inhibitors quinacrine and 7,7-dimethyleicosadienoic acid in isolated globally ischemic rat hearts.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Coronary Circulation; Coronary Disease; Fatty Acids, Unsaturated; Hemodynamics; L-Lactate Dehydrogenase; Male; Muscle Contraction; Muscle, Smooth, Vascular; Myocardial Reperfusion; Phospholipases A; Phospholipases A2; Potassium Chloride; Quinacrine; Rats; Rats, Inbred Strains | 1992 |
Beta-adrenergic regulation of a myocardial actin gene via a cyclic AMP-independent pathway.
Topics: 1-Methyl-3-isobutylxanthine; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Actins; Animals; Animals, Newborn; Blotting, Northern; Bucladesine; Caffeine; Calcimycin; Cells, Cultured; Colforsin; Cyclic AMP; Enkephalins; Gene Expression Regulation; Heart; Heart Ventricles; Isoproterenol; Kinetics; Myocardium; Nifedipine; Potassium Chloride; Propranolol; Protein Precursors; Rats; Receptors, Adrenergic, beta; RNA; RNA, Messenger; Ryanodine | 1992 |
Evidence for the mechanism of the inhibitory action of jatrophone in the isolated rat uterine muscle.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Acetylcholine; Animals; Antineoplastic Agents, Phytogenic; Calcium Channel Blockers; Calcium Channels; Diterpenes; Female; In Vitro Techniques; Muscle, Smooth; Oxytocin; Potassium Chloride; Rats; Uterine Contraction; Uterus | 1990 |
Specific inhibition of long-lasting, L-type calcium channels by synthetic parathyroid hormone.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Arteries; Calcium Channels; Cell Membrane; In Vitro Techniques; Kinetics; Male; Mice; Muscle, Smooth, Vascular; Neuroblastoma; Parathyroid Hormone; Peptide Fragments; Potassium Chloride; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Parathyroid Hormone; Tumor Cells, Cultured | 1990 |
Calcium release from pituitary secretory granules: modulation by thiols, disulfides, and dihydropyridine calcium channel blockers.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channel Blockers; Cattle; Cysteine; Cystine; Cytoplasmic Granules; Dihydropyridines; Disulfides; Dithiothreitol; Glutathione; Hydrogen-Ion Concentration; Mercaptoethanol; Nifedipine; Nimodipine; Pituitary Gland; Potassium Chloride; Sulfhydryl Compounds | 1990 |
Two subtypes of dihydropyridine-sensitive calcium channels in rat ventricular muscle.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Action Potentials; Animals; Calcium Channel Agonists; Calcium Channels; Dihydropyridines; Female; Heart; In Vitro Techniques; Magnesium; Male; Myocardial Contraction; Myocardium; Nifedipine; Potassium Chloride; Pyridines; Rats; Rats, Inbred Strains; Sarcoplasmic Reticulum | 1990 |
Bicarbonate-dependent action of Bay K 8644 in the smooth muscle of the rat vas deferens.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Bicarbonates; In Vitro Techniques; Male; Membrane Potentials; Methacholine Compounds; Muscle Contraction; Muscle, Smooth; Nifedipine; Norepinephrine; Potassium Chloride; Rats; Rats, Inbred Strains; Vas Deferens | 1990 |
Vascular contraction induced by activation of membrane calcium ion channels is enhanced in streptozotocin-diabetes.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Blood Glucose; Body Weight; Calcium; Calcium Channels; Diabetes Mellitus, Experimental; Male; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Potassium Chloride; Rats; Rats, Inbred Strains | 1990 |
Differences in vascular responses to vasoactive agents of basilar artery and aorta from rabbits with alloxan-induced diabetes.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Aorta, Thoracic; Basilar Artery; Blood Glucose; Cyclic AMP; Cyclic GMP; Diabetes Mellitus, Experimental; Endothelium, Vascular; Male; Methylene Blue; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Potassium Chloride; Propranolol; Rabbits; Serotonin | 1990 |
Increased vascular reactivity to Bay K 8644 in genetic hypertension.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcimycin; Carotid Arteries; Endothelium, Vascular; Hemodynamics; Hypertension; In Vitro Techniques; Isometric Contraction; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Norepinephrine; Potassium Chloride; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 1990 |
Pertussis toxin abolishes the effect of neuropeptide Y on rat resistance arteriole contraction.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adenosine Diphosphate Ribose; Animals; Arterioles; Calcium; Female; Neuropeptide Y; Pertussis Toxin; Potassium Chloride; Rats; Rats, Inbred Strains; Splanchnic Circulation; Vascular Resistance; Vasoconstriction; Virulence Factors, Bordetella | 1990 |
Effects of endothelins on nerve-mediated contractions of the mouse vas deferens.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adenosine Triphosphate; Animals; Calcium Channels; Electric Stimulation; Endothelins; Male; Mice; Muscle Contraction; Nicardipine; Norepinephrine; Potassium Chloride; Sympathetic Nervous System; Vas Deferens | 1990 |
Modulation of the [Ca2+] sensitivity of myosin phosphorylation in intact swine arterial smooth muscle.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Endothelins; Histamine; Isometric Contraction; Muscle, Smooth, Vascular; Phosphorylation; Potassium Chloride; Sodium Fluoride; Swine | 1990 |
Calcium dependence of the contraction produced by endothelin (ET-1) in isolated guinea-pig trachea.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channel Blockers; Endothelins; Guinea Pigs; In Vitro Techniques; Indomethacin; Male; Muscle Contraction; Muscle, Smooth; Potassium Chloride; Trachea | 1990 |
Endotoxin-induced impairment of vascular smooth muscle contractions elicited by different mechanisms.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenergic alpha-Agonists; Animals; Aorta, Thoracic; Caffeine; Calcimycin; Calcium; Clonidine; Endothelium, Vascular; Endotoxins; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nitrendipine; Phenylephrine; Potassium Chloride; Rats; Rats, Inbred Strains; Sarcoplasmic Reticulum | 1990 |
Potentiating effect of daunorubicin on vasocontractile responses to KCl and BAY K 8644 in rat aorta.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Aorta, Thoracic; Clonidine; Daunorubicin; Drug Synergism; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Phenylephrine; Potassium Chloride; Rats; Rats, Inbred Strains | 1990 |
Deuterium oxide reduces agonist and depolarization-induced contraction of rat aortic rings.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Aorta, Thoracic; Calcium; Deuterium; Deuterium Oxide; Endothelium, Vascular; In Vitro Techniques; Isoproterenol; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nifedipine; Nitric Oxide; Phenylephrine; Potassium Chloride; Rats; Rats, Inbred Strains; Water | 1990 |
Opiate tolerance-induced modulation of free intracellular calcium in synaptosomes.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Administration, Oral; Animals; Brain; Brain Chemistry; Calcium; Calcium Channels; Drug Administration Schedule; Drug Tolerance; Intracellular Fluid; Mice; Morphine; Narcotics; Nifedipine; Potassium Chloride; Synaptosomes | 1991 |
The inhibitory action of okadaic acid on mechanical responses in guinea-pig vas deferens.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adenosine Triphosphate; Animals; Calcium; Ethers, Cyclic; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Nifedipine; Norepinephrine; Okadaic Acid; Potassium Chloride; Vas Deferens; Vasoconstrictor Agents | 1991 |
Binding of the dihydropyridine calcium channel blocker (+)-[3H] isopropyl-4-(2,1,3-benzoxadiazol-4-yl)-1,4-dihydro-5-methoxycarbonyl-2, 6-dimethyl-3-pyridinecarboxylate (PN200-110) to RINm5F membranes and cells: characterization and functional significanc
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Cell Line; Cell Membrane; Insulin; Insulin Secretion; Islets of Langerhans; Isradipine; Membrane Potentials; Oxadiazoles; Potassium Chloride | 1991 |
Mechanisms involved in the effects of phenidone, diclofenac and ethacrynic acid in rat uterus in vitro.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Chloride; Diclofenac; Dinoprost; Edetic Acid; Ethacrynic Acid; Female; In Vitro Techniques; Lipoxygenase Inhibitors; Methacholine Compounds; Oxytocin; Potassium Chloride; Pyrazoles; Rats; Rats, Inbred Strains; Uterine Contraction; Vanadates | 1991 |
Potentiating effect of NH4Cl on vasoconstriction in rat aorta.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Ammonium Chloride; Animals; Aorta, Thoracic; Drug Synergism; In Vitro Techniques; Kinetics; Male; Muscle, Smooth, Vascular; Nifedipine; Phenylephrine; Potassium Chloride; Rats; Rats, Inbred Strains; Vasoconstriction | 1991 |
A comparison of the effects of angiotensin II and Bay K 8644 on responses to noradrenaline mediated via postjunctional alpha 1-and alpha 2-adrenoceptors in rabbit isolated blood vessels.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenergic alpha-Antagonists; Angiotensin II; Animals; Calcium; Ear; Female; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Norepinephrine; Potassium Chloride; Prazosin; Rabbits; Receptors, Adrenergic, alpha; Regional Blood Flow; Saphenous Vein; Yohimbine | 1991 |
Role of voltage-sensitive calcium channels in mitogenic stimulation of neuroblasts.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Analysis of Variance; Animals; Calcium Channel Blockers; Calcium Channels; Cell Division; Cells, Cultured; DNA Replication; Ganglia, Sympathetic; Insulin; Male; Models, Neurological; Neurons; Nitrendipine; Potassium Chloride; Rats; Rats, Inbred Strains; Tetrodotoxin; Thymidine; Vasoactive Intestinal Peptide; Veratridine | 1991 |
Use-dependent decline in rat aorta sensitivity to contraction by potassium.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Acetylcholine; Aging; Animals; Aorta, Thoracic; In Vitro Techniques; Isoproterenol; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Potassium; Potassium Chloride; Rats; Rats, Inbred Strains; Serotonin | 1991 |
Effects of calcium channel agonists (BAY K 8644, CGP28392 and YC-170) on 45Ca uptake by rat uterine segments.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channel Agonists; Calcium Channels; Female; Nifedipine; Nitrendipine; Potassium Chloride; Pyridines; Rats; Rats, Inbred Strains; Uterus | 1991 |
Phorbol esters induce oscillatory contractions of intestinal smooth muscles.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Atropine; Bradykinin; Calcium; Calcium Channel Blockers; Dihydropyridines; Guinea Pigs; Histamine; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Neuromuscular Depolarizing Agents; Parasympatholytics; Parasympathomimetics; Phorbol Esters; Potassium Chloride; Protein Kinase C | 1991 |
Contractile responses and calcium mobilization in renal arteries of diabetic rats.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Body Weight; Calcium; Calcium Radioisotopes; Diabetes Mellitus, Experimental; In Vitro Techniques; Male; Nifedipine; Norepinephrine; Organ Size; Potassium Chloride; Prazosin; Rats; Rats, Inbred Strains; Renal Artery; Vasoconstriction | 1991 |
The effect of Bay K 8644 on contraction mediated by alpha-adrenoceptors in the rat saphenous vein.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Azepines; Calcium; Drug Synergism; Ion Channels; Male; Methoxamine; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Norepinephrine; Potassium Chloride; Rats; Receptors, Adrenergic, alpha; Saphenous Vein | 1985 |
The effects of the dihydropyridine Bay K 8644 in guinea-pig isolated trachealis.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Acetylcholine; Animals; Calcium Channel Blockers; Calcium Chloride; Electrophysiology; Female; Guinea Pigs; Histamine; In Vitro Techniques; Lanthanum; Male; Muscle Contraction; Muscle, Smooth; Nifedipine; Potassium Chloride; Tetraethylammonium; Tetraethylammonium Compounds; Trachea | 1985 |
Dihydropyridines change the uptake of calcium induced by depolarization into primary cultures of cerebellar granule cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Cells, Cultured; Cerebellum; Ion Channels; Nifedipine; Nitrendipine; Potassium Chloride; Rats; Veratridine | 1985 |
Interaction of dihydropyridine Ca2+ agonist Bay K 8644 with normal and transformed pituitary cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Cell Line; Dose-Response Relationship, Drug; Ion Channels; Nifedipine; Nisoldipine; Pituitary Gland; Pituitary Neoplasms; Potassium Chloride; Prolactin; Rats | 1986 |
Atrial natriuretic factor does not affect basal, forskolin- and CRF-stimulated adenylate cyclase activity, cAMP formation or ACTH secretion, but does stimulate cGMP synthesis in anterior pituitary.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adenylyl Cyclases; Adrenocorticotropic Hormone; Animals; Atrial Natriuretic Factor; Cell Line; Colforsin; Corticotropin-Releasing Hormone; Cyclic AMP; Cyclic GMP; Growth Hormone; Kinetics; Mice; Nifedipine; Pituitary Gland, Anterior; Potassium Chloride; Tetradecanoylphorbol Acetate | 1986 |
The facilitative actions of Bay K 8644 on norepinephrine and KCl-induced contractures of rabbit aortic rings.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Aorta; Dose-Response Relationship, Drug; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Norepinephrine; Potassium Chloride; Rabbits | 1986 |
Effects of Bay K 8644 and nifedipine on femoral arteries of spontaneously hypertensive rats.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channel Blockers; Femoral Artery; Hypertension; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Norepinephrine; Potassium; Potassium Chloride; Rats; Rats, Inbred SHR | 1986 |
Effects of Bay K 8644 on contraction of the human isolated bronchus and guinea-pig isolated trachea.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Acetylcholine; Animals; Bronchi; Calcium; Calcium Channel Blockers; Guinea Pigs; Histamine; Humans; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Nicardipine; Nifedipine; Potassium Chloride; Trachea; Verapamil | 1986 |
Bay K 8644 stimulation of calcium entry and endogenous dopamine release in rat striatal synaptosomes antagonized by nimodipine.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channel Blockers; Corpus Striatum; Dopamine; Electric Stimulation; Kinetics; Male; Nicotinic Acids; Nifedipine; Nimodipine; Potassium Chloride; Rats; Rats, Inbred Strains; Synaptosomes | 1986 |
Possible role of surface potential in the gating mechanism of Ca channels concerned with catecholamine secretion in the adrenal.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenal Glands; Animals; Calcium; Catecholamines; Cations, Divalent; Cats; Cesium; Egtazic Acid; Ion Channels; Membrane Potentials; Nifedipine; Potassium Chloride; Rubidium; Sodium Chloride; Strontium; Sucrose | 1986 |
Pharmacologic and radioligand binding analysis of the actions of 1,4-dihydropyridine activator-antagonist pairs in smooth muscle.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Binding, Competitive; Calcium; Drug Synergism; Guinea Pigs; Ion Channels; Muscle Contraction; Muscle, Smooth, Vascular; Nicotinic Acids; Nitrendipine; Oxadiazoles; Potassium Chloride; Rats; Stereoisomerism | 1986 |
The calcium channel agonist BAY K8644 enhances the responsiveness of human airway muscle to KCl and histamine but not to carbachol.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Aged; Calcium; Calcium Channel Blockers; Carbachol; Drug Synergism; Histamine; Humans; In Vitro Techniques; Ion Channels; Lung; Muscle Contraction; Muscle Tonus; Muscle, Smooth; Potassium Chloride | 1987 |
BAY K 8644, a calcium channel agonist, inhibits renin secretion in vitro.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channel Blockers; Chelating Agents; In Vitro Techniques; Kidney Cortex; Kinetics; Male; Potassium Chloride; Rats; Rats, Inbred Strains; Renin | 1987 |
Effects of dihydropyridines on stress, myosin phosphorylation, and V0 in smooth muscle.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channel Blockers; Dose-Response Relationship, Drug; Muscle Contraction; Muscle, Smooth, Vascular; Myosins; Nifedipine; Phosphorylation; Potassium Chloride; Swine | 1987 |
PC12 cells: a model system for studying drug effects on dopamine synthesis and release.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Brocresine; Cells, Cultured; Cresols; Dihydroxyphenylalanine; Dopamine; Models, Biological; Nitrendipine; Pheochromocytoma; Potassium Chloride; Rats; Reserpine; Sulfonamides | 1987 |
Effects of Bay K 8644 on the electrically evoked and KCl-evoked norepinephrine release and the corresponding contraction in isolated canine saphenous veins.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Dogs; Electric Stimulation; In Vitro Techniques; Ion Channels; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Nisoldipine; Norepinephrine; Potassium Chloride; Saphenous Vein | 1987 |
45Ca uptake and the actions of Bay K 8644 on aortic strips from rabbits with perinephritis hypertension.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Aorta, Thoracic; Arteries; Calcium; Calcium Radioisotopes; Drug Interactions; Hypertension, Renal; In Vitro Techniques; Nephritis; Norepinephrine; Potassium Chloride; Rabbits | 1987 |
Parathyroid hormone and calcium entry blockade in a vascular tissue.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Arginine Vasopressin; Arteries; Calcium; Male; Muscle, Smooth, Vascular; Parathyroid Hormone; Peptide Fragments; Potassium Chloride; Rats; Rats, Inbred Strains; Tail; Vasodilation | 1988 |
Voltage-sensitive calcium channels in differentiated neuroblastoma X glioma hybrid (NG108-15) cells: characterization by quin 2 fluorescence.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Aminoquinolines; Animals; Bucladesine; Calcium; Cricetinae; Dihydropyridines; Fluorescent Dyes; Glioma; Humans; Hybrid Cells; Ion Channels; Membrane Potentials; Neuroblastoma; Potassium Chloride; Sodium; Tetrodotoxin; Veratridine | 1988 |
Altered effect of BAY K 8644 after exposure of the rat aorta to IBMX or Db cAMP.
Topics: 1-Methyl-3-isobutylxanthine; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Aorta; Bucladesine; Cyclic AMP; Dihydropyridines; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Potassium Chloride; Rats; Rats, Inbred Strains; Theophylline | 1988 |
Pressor responses induced by Bay K 8644 involve both release of adrenal catecholamines and calcium channel activation.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenal Glands; Adrenergic alpha-Antagonists; Animals; Aorta, Thoracic; Blood Pressure; Calcium Channel Blockers; Catecholamines; In Vitro Techniques; Ion Channels; Male; Muscle, Smooth, Vascular; Potassium Chloride; Rabbits; Rats; Rats, Inbred Strains | 1988 |
Characterization of dihydropyridine-sensitive calcium channels in rat brain synaptosomes.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Brain; Calcium; Centrifugation, Density Gradient; Dihydropyridines; Dopamine; Ion Channels; Potassium Chloride; Rats; Synaptosomes | 1988 |
Mechanism of adenosine receptor-induced renal vasoconstriction in rats.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adenosine; Animals; Gallopamil; In Vitro Techniques; Kidney; Male; Pertussis Toxin; Potassium Chloride; Rats; Rats, Inbred Strains; Receptors, Purinergic; Reference Values; Renal Circulation; Vasoconstriction; Virulence Factors, Bordetella | 1988 |
Pharmacological analysis of the effects of Bay K 8644 and organic calcium antagonists on the mouse isolated distal colon.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Acetylcholine; Animals; Calcium Channel Blockers; Colon; In Vitro Techniques; Mice; Muscle Relaxation; Muscle, Smooth; Nifedipine; Potassium Chloride; Tetrodotoxin | 1988 |
Potentiation by neuropeptide Y of vasoconstriction in rat resistance arteries.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Arteries; Calcium; Calcium Channel Blockers; Dinoprost; Female; In Vitro Techniques; Muscle Contraction; Neuropeptide Y; Nitrendipine; Norepinephrine; Potassium Chloride; Rats; Rats, Inbred Strains; Serotonin; Vasoconstriction | 1988 |
Bay K 8644-induced potentiation of the contractile response of rabbit iliac artery to caffeine in a Ca2+-free medium.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Caffeine; Calcium; Calcium Chloride; Egtazic Acid; Iliac Artery; In Vitro Techniques; Lanthanum; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Potassium Chloride; Rabbits; Vanadates | 1989 |
Assessment in pig coronary artery of long-lasting and potent calcium antagonistic actions of the novel dihydropyridine derivative mepirodipine hydrochloride.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channel Agonists; Calcium Channel Blockers; Coronary Vessels; Female; In Vitro Techniques; Isometric Contraction; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Nitrendipine; Potassium Chloride; Swine | 1989 |
Age influences responses of rat isolated aorta and pulmonary artery to the calcium channel agonist, Bay K 8664, and to potassium and calcium.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Aging; Animals; Aorta, Thoracic; Caffeine; Calcimycin; Calcium; Calcium Chloride; Male; Muscle, Smooth, Vascular; Potassium; Potassium Chloride; Pulmonary Artery; Rats; Rats, Inbred Strains | 1989 |
Sensitization alters contractile responses and calcium influx in human airway smooth muscle.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Aged; Bronchi; Calcium; Carbachol; Female; Histamine; Humans; Immunization; In Vitro Techniques; Male; Middle Aged; Muscle Contraction; Muscle, Smooth; Potassium Chloride | 1989 |
Vascular smooth muscle function in rats with acute renal failure.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Acute Kidney Injury; Animals; Azepines; In Vitro Techniques; Male; Methoxamine; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Norepinephrine; Portal Vein; Potassium Chloride; Rats; Urea | 1989 |
Regulation by calcium and myosin phosphorylation of the development and maintenance of stress in vascular smooth muscle.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; In Vitro Techniques; Muscle Contraction; Muscle, Smooth, Vascular; Myosins; Nifedipine; Phosphorylation; Potassium Chloride; Swine | 1989 |
ATP receptor-induced Ca2+ transients in cardiac myocytes: sources of mobilized Ca2+.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adenosine Triphosphate; Animals; Benzofurans; Calcium; Cells, Cultured; Fluorescent Dyes; Fura-2; Heart; Heart Ventricles; Ionomycin; Kinetics; Nifedipine; Potassium Chloride; Rats; Rats, Inbred Strains; Receptors, Purinergic; Ryanodine; Spectrometry, Fluorescence; Ventricular Function | 1989 |
The selective potentiation of noradrenaline-induced tone by Bay K 8644 in the rabbit basilar artery.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Basilar Artery; Drug Synergism; Histamine; In Vitro Techniques; Kinetics; Male; Muscle Contraction; Muscle Tonus; Muscle, Smooth, Vascular; Norepinephrine; Potassium Chloride; Rabbits | 1989 |
Multiple sources of calcium for contraction of the human urinary bladder muscle.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Aged; Caffeine; Calcium; Carbachol; Endothelins; Female; Humans; In Vitro Techniques; Lanthanum; Male; Middle Aged; Mollusk Venoms; Muscle Contraction; Neurokinin A; Nickel; Nifedipine; omega-Conotoxins; Peptides; Potassium Chloride; Procaine; Urinary Bladder | 1989 |
Calcium mobilization and influx during the biphasic cytosolic calcium and secretory responses in agonist-stimulated pituitary gonadotrophs.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Biological Transport, Active; Calcium; Cells, Cultured; Cytosol; Egtazic Acid; Female; Gonadotropin-Releasing Hormone; Kinetics; Luteinizing Hormone; Nifedipine; Ovariectomy; Pituitary Gland, Anterior; Potassium Chloride; Rats | 1989 |
Mechanism of contraction to endothelin in isolated porcine coronary artery.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Acetylcholine; Animals; Calcium; Calcium Channels; Coronary Vessels; Dinoprost; Endothelins; Endothelium, Vascular; Histamine; In Vitro Techniques; Kinetics; Membrane Potentials; Muscle, Smooth, Vascular; Nicardipine; Peptides; Potassium Chloride; Receptors, Nicotinic; Swine; Vasoconstriction | 1989 |
Potentiation by treatment with reserpine of alpha 2-adrenoceptor-mediated contractions of rat tail artery.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Arteries; Drug Synergism; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Potassium Chloride; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Regional Blood Flow; Reserpine; Tail | 1989 |
Studies on the mechanism of action of the vasoconstrictive dihydropyridine, CGP 28392.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channel Blockers; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Male; Nifedipine; Potassium Chloride; Pyridines; Rabbits; Vasoconstriction; Vasoconstrictor Agents | 1984 |
Allosteric interactions at L-type calcium channels between FPL 64176 and the enantiomers of the dihydropyridine Bay K 8644.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Allosteric Regulation; Animals; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Guinea Pigs; In Vitro Techniques; Ion Channel Gating; Membrane Potentials; Muscle Contraction; Muscle, Smooth; Potassium Chloride; Pyrroles; Stereoisomerism | 1995 |
Effects of nifedipine and Bay K 8644 on myotropic responses in aortic rings of pregnant rats.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Aorta, Thoracic; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Kinetics; Muscle Contraction; Nifedipine; Nitrendipine; Phenylephrine; Potassium Chloride; Pregnancy; Pregnancy, Animal; Rats; Rats, Sprague-Dawley; Tritium | 1995 |
Modulation of acetylcholine release in rat hippocampus by amino alcohols and Bay K 8644.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Acetylcholine; Animals; Calcium; Cerebral Cortex; Choline; Corpus Striatum; Diltiazem; Dose-Response Relationship, Drug; Ethanolamine; Ethanolamines; Flunarizine; Hippocampus; In Vitro Techniques; Male; Nifedipine; Osmolar Concentration; Potassium Chloride; Propanolamines; Pyrrolidines; Rats; Rats, Inbred F344; Verapamil | 1993 |
Mechanisms of myogenic enhancement by norepinephrine.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Alkaloids; Animals; Arterioles; Blood Flow Velocity; Blood Pressure; Male; Microcirculation; Muscle Contraction; Muscle, Smooth, Vascular; Muscles; Naphthalenes; Nifedipine; Norepinephrine; Phentolamine; Polycyclic Compounds; Potassium Chloride; Propranolol; Protein Kinase C; Rats; Rats, Sprague-Dawley; Staurosporine; Vasoconstriction | 1994 |
[Effects of praeruptorin-C on cytosolic free calcium in cultured rat heart cells].
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channel Blockers; Calcium Chloride; Cells, Cultured; Coumarins; Dose-Response Relationship, Drug; Myocardium; Potassium Chloride; Rats; Rats, Wistar | 1993 |
Multiple mitogenic signalling pathways in chromaffin cells: a model for cell cycle regulation in the nervous system.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenal Medulla; Animals; Cell Cycle; Cell Division; Cells, Cultured; Colforsin; Dexamethasone; Ethers, Cyclic; Female; Models, Neurological; Nerve Endings; Nerve Growth Factors; Okadaic Acid; Phosphoprotein Phosphatases; Potassium Chloride; Rats; Rats, Inbred F344; Signal Transduction; Tetradecanoylphorbol Acetate; Tetrodotoxin; Veratridine | 1994 |
Role of lipoxygenase metabolites of arachidonic acid in the regulation of adrenocorticotropin secretion by perifused rat anterior pituitary cells.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 8-Bromo Cyclic Adenosine Monophosphate; Adrenocorticotropic Hormone; Animals; Arachidonic Acid; Arginine Vasopressin; Calcium; Cells, Cultured; Corticotropin-Releasing Hormone; Diglycerides; Eicosanoids; Hydroxyeicosatetraenoic Acids; Indomethacin; Ionomycin; Lipoxygenase; Male; Masoprocol; Pituitary Gland, Anterior; Potassium Chloride; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Tritium | 1994 |
Oscillations of cytosolic calcium in rat chromaffin cells: dual modulation in frequency and amplitude.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Activity Cycles; Adrenal Medulla; Animals; Apamin; Bradykinin; Calcium; Calcium Channel Blockers; Cells, Cultured; Cytosol; Female; Kinetics; Microscopy, Fluorescence; Oscillometry; Potassium Chloride; Rats; Rats, Inbred F344; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin | 1994 |
Inhibitory effect of okadaic acid on noradrenaline exocytosis from guinea-pig vas deferens.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adenosine Triphosphate; Animals; Calcium; Calcium Channels; Ethers, Cyclic; Exocytosis; Guinea Pigs; In Vitro Techniques; Kinetics; Male; Norepinephrine; Okadaic Acid; Ouabain; Phosphoprotein Phosphatases; Potassium Chloride; Time Factors; Vas Deferens | 1994 |
Contractile hyperreactivity and alteration of PKC activity in gastric fundus smooth muscle of diabetic rats.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Acetylcholine; Animals; Calcium Channels; Cell Membrane; Diabetes Mellitus, Experimental; Gastric Fundus; In Vitro Techniques; Isoquinolines; Isradipine; Male; Muscle Contraction; Muscle, Smooth; Norepinephrine; Piperazines; Potassium Chloride; Protein Kinase C; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate | 1994 |
Inhibition of dihydropyridine-sensitive calcium entry in hypoxic relaxation of airway smooth muscle.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Bronchi; Calcium; Calcium Channel Blockers; Carbachol; Dihydropyridines; Female; Hypoxia; Male; Muscle Relaxation; Muscle, Smooth; Nifedipine; Potassium Chloride; Swine | 1995 |
Effects of 2,5-di(tert-butyl)-1,4-hydroquinone, an endoplasmic reticulum Ca(2+)-ATPase inhibitor, on agonist-stimulated phasic myometrial contractions.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium-Transporting ATPases; Dinoprost; Dose-Response Relationship, Drug; Endoplasmic Reticulum; Female; Hydroquinones; Ionomycin; Myometrium; Oxytocin; Potassium Chloride; Rats; Rats, Sprague-Dawley; Uterine Contraction | 1995 |
Enhanced vascular responsiveness to Bay K 8644 in mineralocorticoid- and N-nitro arginine-induced hypertension.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Administration, Oral; Amino Acid Oxidoreductases; Animals; Aorta, Thoracic; Arginine; Blood Pressure; Calcium Channels; Desoxycorticosterone; Dose-Response Relationship, Drug; Drug Implants; Hypertension; Male; Mesenteric Artery, Superior; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Phenylephrine; Potassium Chloride; Rats; Rats, Sprague-Dawley; Sodium Chloride, Dietary; Stress, Mechanical; Vasoconstriction | 1994 |
Apoptosis in cerebellar granule cells is blocked by high KCl, forskolin, and IGF-1 through distinct mechanisms of action: the involvement of intracellular calcium and RNA synthesis.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Apoptosis; Calcium; Cerebellum; Colforsin; Electrophysiology; Insulin-Like Growth Factor I; Intracellular Membranes; Neurons; Nifedipine; Potassium; Potassium Chloride; Rats; Rats, Wistar; RNA; Transcription, Genetic | 1995 |
Modulation of the dihydropyridine-insensitive Ca2+ influx by 8-bromo-guanosine-3':5'-monophosphate, cyclic (8-Br-cGMP) in bovine adrenal chromaffin cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenal Medulla; Animals; Bucladesine; Calcium; Calcium Channels; Cattle; Cells, Cultured; Cyclic GMP; Dihydropyridines; Neomycin; Nerve Tissue Proteins; omega-Agatoxin IVA; omega-Conotoxin GVIA; Peptides; Potassium Chloride; Second Messenger Systems; Spider Venoms | 1994 |
Role of extracellular Ca2+ in the selective enhancement of contractile responses of arteries from diabetic rats to noradrenaline.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Arteries; Calcium; Calcium Channel Blockers; Diabetes Mellitus, Experimental; In Vitro Techniques; Male; Norepinephrine; Potassium Chloride; Rats; Rats, Wistar; Vasoconstriction | 1994 |
NMDA receptor involvement in endothelin neurotoxicity in rat striatal slices.
Topics: 2-Amino-5-phosphonovalerate; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Dopamine; Endothelins; In Vitro Techniques; Male; N-Methylaspartate; Neostriatum; Neurons; Nifedipine; Potassium; Potassium Chloride; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 1995 |
A pharmacological analysis of calcium channels involved in phasic and tonic responses of the guinea-pig ureter to high potassium.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Cadmium; Cadmium Chloride; Calcium Channels; Chlorides; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Nickel; Nifedipine; Potassium Chloride; Ureter | 1995 |
The effects of thimerosal, a sulfhydryl reagent, on phasic myometrial contractions.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Aluminum Compounds; Animals; Calcium; Cytosol; Estrus; Female; Fluorides; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Ionomycin; Muscle, Smooth; Myometrium; Oxytocin; Potassium Chloride; Proestrus; Rats; Rats, Sprague-Dawley; Thimerosal; Time Factors; Uterine Contraction | 1995 |
Effects of magnesium ions on detrusor contraction in rat.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channels; Carbachol; Female; In Vitro Techniques; Intracellular Fluid; Magnesium; Magnesium Chloride; Muscle Contraction; Potassium Chloride; Rats; Rats, Wistar; Stimulation, Chemical; Tetrodotoxin; Urinary Bladder; Verapamil | 1995 |
Platelet-activating factor mediated potentiation of stimulation-evoked catecholamine release and the rise in intracellular free Ca2+ concentration in adrenal chromaffin cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Acetylcholine; Adrenal Glands; Animals; Azepines; Caffeine; Calcium; Catecholamines; Cattle; Cells, Cultured; Chromaffin Granules; Dose-Response Relationship, Drug; Kinetics; Platelet Activating Factor; Platelet Membrane Glycoproteins; Potassium Chloride; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Stimulation, Chemical; Time Factors; Triazoles | 1995 |
Effects of the novel water-soluble calcium antagonist (+/-)-3-(4-allyl-1-piperazinyl)-2,2-dimethylpropyl methyl 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylate dihydrochloride on the responses of isolated canine arteries.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Arteries; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Dihydropyridines; Dogs; Female; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nicardipine; Nifedipine; Norepinephrine; Potassium Chloride; Vasoconstrictor Agents; Vasodilator Agents | 1995 |
Vasorelaxant effect of the analgesic clonixin on rat aorta.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Analgesics; Animals; Aorta, Thoracic; Blood Pressure; Calcium; Clonixin; Drug Interactions; Female; In Vitro Techniques; Indomethacin; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Potassium Chloride; Rats; Rats, Sprague-Dawley; Verapamil | 1995 |
Influence of hormonal status in relaxant effect of diethylstilbestrol and nifedipine on isolated rat uterus contraction.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Diethylstilbestrol; Dose-Response Relationship, Drug; Female; Hormones; Muscle Contraction; Nifedipine; Potassium Chloride; Rats; Rats, Wistar; Uterus | 1995 |
The effect of calcium channel antagonists and BAY K 8644 on calcium fluxes of malignant hyperpyrexia-susceptible muscle.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Caffeine; Calcium; Calcium Channel Blockers; Calcium-Transporting ATPases; Diltiazem; Halothane; Malignant Hyperthermia; Muscle Contraction; Muscles; Nifedipine; Potassium Chloride; Sarcoplasmic Reticulum; Swine; Verapamil | 1993 |
Specific bindings of [3H](+)PN200-110 and [125I]omega-conotoxin to crude membranes from differentiated NG108-15 cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Brain; Bucladesine; Cell Differentiation; Cell Membrane; Diltiazem; Glioma; Hybrid Cells; Isradipine; Mollusk Venoms; Neuroblastoma; Nitrendipine; omega-Conotoxin GVIA; Potassium Chloride; Rats; Tumor Cells, Cultured; Verapamil | 1993 |
Activation of protein kinase C increases Ca2+ sensitivity of secretory response of GH3 pituitary cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Dose-Response Relationship, Drug; Egtazic Acid; Enzyme Activation; Epidermal Growth Factor; ErbB Receptors; Kinetics; Pituitary Neoplasms; Potassium Chloride; Prolactin; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate; Thyrotropin-Releasing Hormone; Tumor Cells, Cultured | 1993 |
Isolated rat glomerular cells demonstrate L-type Ca(2+)-channel activity.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Biological Transport; Calcium; Calcium Channel Blockers; Calcium Channels; Glomerular Mesangium; Gramicidin; Ion Channel Gating; Kidney Glomerulus; Male; Membrane Potentials; Potassium Chloride; Rats; Rats, Sprague-Dawley; Verapamil | 1993 |
Effect of TMB-8 on alpha-adrenoceptor agonist and KC1 induced-contractions in isolated rabbit aorta.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenergic alpha-Agonists; Animals; Aorta, Thoracic; Gallic Acid; In Vitro Techniques; Methoxamine; Muscle Contraction; Muscle, Smooth, Vascular; Phenylephrine; Potassium Chloride; Rabbits; Receptors, Adrenergic, alpha-1 | 1993 |
Inhibitory effect of amylin (islet amyloid polypeptide) on insulin response to non-glucose stimuli. Study in perfused rat pancreas.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Amyloid; Animals; Calcium Channel Agonists; Glucose; Hypoglycemic Agents; In Vitro Techniques; Islet Amyloid Polypeptide; Islets of Langerhans; Kinetics; Male; Perfusion; Phospholipids; Potassium Channel Blockers; Potassium Chloride; Rats; Rats, Wistar; Sincalide; Time Factors; Tolbutamide | 1995 |
Selective up-regulation of alpha 1-chimaerin mRNA in SK-N-SH neuroblastoma cells by K+/-induced depolarisation.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Calcium Channels; Calcium Channels, L-Type; Cell Differentiation; Cell Line; Cell Nucleus; Culture Media, Serum-Free; DNA; Gene Expression Regulation, Neoplastic; GTPase-Activating Proteins; Humans; Kinetics; Membrane Potentials; Neuroblastoma; Neurons; Nifedipine; Osmolar Concentration; Potassium; Potassium Chloride; Protein Biosynthesis; RNA, Messenger; Thymidine; Time Factors; Transcription, Genetic; Tumor Cells, Cultured | 1996 |
Augmented contractile function and abnormal Ca2+ handling in the aorta of Zucker obese rats with insulin resistance.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenergic alpha-Agonists; Animals; Aorta; Calcium; Calcium Channel Agonists; Calcium Channels; Hyperinsulinism; In Vitro Techniques; Insulin Resistance; Ion Channel Gating; Male; Membrane Potentials; Muscle Contraction; Muscle, Smooth, Vascular; Obesity; Phenylephrine; Potassium Chloride; Rats; Rats, Wistar; Rats, Zucker; Vasodilation | 1996 |
NIDDM is associated with loss of pancreatic beta-cell L-type Ca2+ channel activity.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channels; Diabetes Mellitus, Type 2; Electrophysiology; Gene Expression; Glucose; Intracellular Membranes; Islets of Langerhans; Male; Osmolar Concentration; Patch-Clamp Techniques; Potassium Chloride; Rats; Rats, Zucker; RNA, Messenger | 1996 |
Meiosis reinitiation in Ruditapes philippinarum (Mollusca): involvement of L-calcium channels in the release of metaphase I block.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Bivalvia; Boron Compounds; Calcium Channel Agonists; Calcium Channels; Calcium Channels, L-Type; Dihydropyridines; Electrophysiology; Female; Fertilization in Vitro; Fluorescence; Isradipine; Male; Meiosis; Metaphase; Oocytes; Potassium Chloride; Prophase; Serotonin | 1996 |
Huperzine A, a potential therapeutic agent for dementia, reduces neuronal cell death caused by glutamate.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Acetylcholinesterase; Alkaloids; Animals; Calcium; Cell Death; Cell Survival; Cells, Cultured; Embryo, Mammalian; Glutamic Acid; Neurons; Neuroprotective Agents; Neurotoxins; Potassium Chloride; Prosencephalon; Rats; Rats, Sprague-Dawley; Sesquiterpenes | 1997 |
Involvement of both L- and N-type voltage-dependent Ca2+ channels in KCl- and veratridine-evoked transmitter release from non-adrenergic, non-cholinergic nerves in the rabbit iris sphincter muscle.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Analgesics; Animals; Atropine; Calcium Channel Blockers; Calcium Channels; Capsaicin; Iris; Male; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Nicardipine; omega-Agatoxin IVA; omega-Conotoxin GVIA; Peptides; Potassium Chloride; Rabbits; Receptors, Tachykinin; Sodium Channels; Spider Venoms; Substance P; Synaptic Transmission; Veratridine | 1997 |
Spontaneous and repetitive calcium transients in C2C12 mouse myotubes during in vitro myogenesis.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adenosine Triphosphate; Animals; Apamin; Caffeine; Calcium; Cell Differentiation; Cell Line; Cytosol; Egtazic Acid; Kinetics; Membrane Potentials; Mice; Microscopy, Confocal; Microscopy, Video; Muscle, Skeletal; Oscillometry; Potassium Chloride; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin; Verapamil | 1997 |
Gonadotropin subunit and gonadotropin-releasing hormone receptor gene expression are regulated by alterations in the frequency of calcium pulsatile signals.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channel Agonists; Cells, Cultured; Female; Follicle Stimulating Hormone; Gene Expression Regulation; Gonadotropin-Releasing Hormone; Luteinizing Hormone; Pituitary Gland; Potassium Chloride; Pulsatile Flow; Rats; Receptors, LHRH; RNA, Messenger; Signal Transduction | 1997 |
Bethanechol activates a post-receptor negative feedback mechanism in rabbit urinary bladder smooth muscle.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Bethanechol; Caffeine; Feedback; Female; Muscarinic Agonists; Muscle Contraction; Muscle, Smooth; Potassium Chloride; Rabbits; Swine; Time Factors; Urinary Bladder | 1998 |
The role of voltage-gated Ca2+ channels in neurite growth of cultured chromaffin cells induced by extremely low frequency (ELF) magnetic field stimulation.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenal Medulla; Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Cells, Cultured; Chromaffin Cells; Electromagnetic Fields; Ion Channel Gating; Mollusk Venoms; Nerve Growth Factors; Neurites; Nifedipine; Norepinephrine; Potassium Chloride; Rats; Rats, Wistar | 1998 |
A role for L-type calcium channels in developmental regulation of transmitter phenotype in primary sensory neurons.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels; Electric Stimulation; Female; Gene Expression Regulation, Developmental; Ion Channel Gating; Long-Term Potentiation; Membrane Potentials; Neuronal Plasticity; Neurons, Afferent; Neurotransmitter Agents; Nimodipine; omega-Conotoxin GVIA; Peptides; Phenotype; Potassium Chloride; Pregnancy; Rats; Rats, Sprague-Dawley; Substance P; Tyrosine 3-Monooxygenase | 1998 |
Ceramide selectively inhibits calcium-mediated potentiation of beta-adrenergic-stimulated cyclic nucleotide accumulation in rat pinealocytes.
Topics: 1-Methyl-3-isobutylxanthine; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenergic beta-Antagonists; Analgesics, Opioid; Animals; Calcium; Ceramides; Cyclic AMP; Cyclic GMP; Drug Synergism; Genistein; Isoproterenol; Male; Meperidine; Phenylephrine; Pineal Gland; Potassium; Potassium Chloride; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate | 1998 |
Endothelin-1 inhibits voltage-sensitive Ca2+ channels in cultured rat cerebellar granule neurones via the ET-A receptor.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Calcium Signaling; Cerebellum; Dose-Response Relationship, Drug; Endothelin-1; Male; Nerve Tissue Proteins; Neurons; Oligopeptides; Patch-Clamp Techniques; Peptides, Cyclic; Potassium; Potassium Chloride; Rats; Rats, Wistar; Receptor, Endothelin A; Receptors, Cholinergic; Receptors, Endothelin; Second Messenger Systems; Viper Venoms | 1998 |
Tyrosine hydroxylase expression in primary cultures of olfactory bulb: role of L-type calcium channels.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Cells, Cultured; Colforsin; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Nerve Tissue Proteins; Neurites; Nifedipine; Olfactory Bulb; Potassium Chloride; Stimulation, Chemical; Time Factors; Tyrosine 3-Monooxygenase | 1998 |
Synergistic actions of insulin and troglitazone on contractility in endothelium-denuded rat aortic rings.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Aorta, Thoracic; Calcium; Chromans; Endothelium, Vascular; Hypoglycemic Agents; In Vitro Techniques; Insulin; Isometric Contraction; Male; Muscle, Smooth, Vascular; Phenylephrine; Potassium Chloride; Rats; Rats, Sprague-Dawley; Thiazoles; Thiazolidinediones; Troglitazone; Vasodilator Agents | 1998 |
Sex differences in extracellular and intracellular calcium-mediated vascular reactivity to vasopressin in rat aorta.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Aorta; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Diltiazem; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Male; Potassium Chloride; Rats; Rats, Sprague-Dawley; Sex Characteristics; Simvastatin; Vasoconstriction; Vasopressins | 1998 |
Blockade by NS-7, a neuroprotective compound, of both L-type and P/Q-type Ca2+ channels involving depolarization-stimulated nitric oxide synthase activity in primary neuronal culture.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Agatoxins; Animals; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Calcium Channels, N-Type; Cells, Cultured; Cyclic GMP; Electrophysiology; Mice; Nerve Tissue Proteins; Neurons; Neuroprotective Agents; Nifedipine; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Potassium Chloride; Pyrimidines; Spider Venoms | 1999 |
Sorting of a constitutive secretory protein to the regulated secretory pathway of exocrine cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Alkaline Phosphatase; Amylases; Animals; Barium Compounds; Butyrates; Cell Line; Chlorides; Cholecystokinin; Cycloheximide; Cytoplasmic Granules; Dexamethasone; Pancreas; Potassium Chloride; Rats; Substance P; Tetradecanoylphorbol Acetate; Transfection | 1999 |
Inhibitory effects of melatonin on free intracellular calcium in mouse brain cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Aging; Animals; Biological Transport, Active; Brain; Calcium; Calcium Channel Blockers; Female; Male; Melatonin; Mice; Potassium Chloride; Random Allocation; Sodium Glutamate | 1999 |
Ceramide inhibits L-type calcium channel currents in rat pinealocytes.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Ceramides; Drug Synergism; Enzyme Inhibitors; Glucosyltransferases; Interleukin-1; Isoproterenol; Male; Norepinephrine; Nucleotides, Cyclic; Patch-Clamp Techniques; Phenols; Pineal Gland; Potassium Chloride; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley; Sphingomyelin Phosphodiesterase | 1999 |
Ceramide enhances growth hormone (GH)-releasing hormone-stimulated cyclic adenosine 3',5'-monophosphate accumulation but inhibits GH release in rat anterior pituitary cells.
Topics: 1-Methyl-3-isobutylxanthine; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channel Agonists; Ceramides; Colforsin; Cyclic AMP; Glucosyltransferases; Growth Hormone; Growth Hormone-Releasing Hormone; Ionomycin; Ionophores; Male; Meperidine; Pituitary Gland, Anterior; Potassium Chloride; Rats; Rats, Sprague-Dawley | 1999 |
Inhibition of cADP-ribose formation produces vasodilation in bovine coronary arteries.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adenosine; Adenosine Diphosphate Ribose; ADP-ribosyl Cyclase; Animals; Calcium Channel Agonists; Calcium Channels; Cattle; Coronary Circulation; Coronary Vessels; Cyclic ADP-Ribose; Iloprost; Niacinamide; Phosphorus-Oxygen Lyases; Potassium Chloride; Ryanodine; Vasoconstriction; Vasodilation; Vasodilator Agents | 2000 |
Impairment of Ca(2+) mobilization in circular muscle cells of the inflamed colon.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Acetylcholine; Animals; Calcium; Calcium Channel Agonists; Calcium Radioisotopes; Cell Membrane Permeability; Cell Size; Colitis; Cytosol; Dogs; Inositol 1,4,5-Trisphosphate; Kinetics; Muscle Contraction; Muscle, Smooth; Potassium Chloride; Ryanodine; Tritium | 2000 |
Differential activation of brain-derived neurotrophic factor gene promoters I and III by Ca2+ signals evoked via L-type voltage-dependent and N-methyl-D-aspartate receptor Ca2+ channels.
Topics: 2-Amino-5-phosphonovalerate; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Brain-Derived Neurotrophic Factor; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Signaling; Cells, Cultured; Cerebral Cortex; Embryo, Mammalian; Gene Expression Regulation; Neurons; Potassium Chloride; Promoter Regions, Genetic; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Recombinant Fusion Proteins; Transfection | 2000 |
Effect of erythromycin on ATP-induced intracellular calcium response in A549 cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adenosine Triphosphate; Anti-Bacterial Agents; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Erythromycin; Estrenes; Humans; Inositol 1,4,5-Trisphosphate; Intracellular Membranes; Lung; Nickel; Potassium Chloride; Protein Isoforms; Pyrrolidinones; Receptors, Purinergic P2; Receptors, Purinergic P2X2; Tumor Cells, Cultured; Uridine Triphosphate; Verapamil | 2000 |
Slow death of postnatal hippocampal neurons by GABA(A) receptor overactivation.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channel Agonists; Cell Death; Cells, Cultured; Excitatory Amino Acid Agonists; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Hippocampus; N-Methylaspartate; Neurons; Potassium Chloride; Rats; Receptors, GABA-A | 2000 |
Functional alteration of dihydropyridine-sensitive Ca(2+) channels in the adrenal glomerulosa of pregnant rats.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Blotting, Western; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Radioisotopes; Cell Membrane; Female; Nifedipine; Nitrendipine; Potassium Chloride; Pregnancy; Pregnancy, Animal; Rats; Rats, Sprague-Dawley; Tritium; Verapamil; Zona Glomerulosa | 2000 |
Changes of the potassium currents in rat aortic smooth muscle cells during postnatal development.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 4-Aminopyridine; Aging; Animals; Aorta, Thoracic; Calcium; Calcium Channel Agonists; Charybdotoxin; Electric Conductivity; Male; Membrane Potentials; Muscle Contraction; Muscle Development; Muscle, Smooth, Vascular; Norepinephrine; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels; Potassium Chloride; Rats; Rats, Wistar; Tetraethylammonium; Vasoconstriction | 2000 |
Differential effects of agonists of aldosterone secretion on steroidogenic acute regulatory phosphorylation.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Animals; Blotting, Western; Calcium Channel Agonists; Cattle; Cells, Cultured; Colforsin; Electrophoresis, Gel, Two-Dimensional; Phosphoproteins; Phosphorylation; Potassium Chloride; Protein Kinase C; Signal Transduction; Tetradecanoylphorbol Acetate; Vasoconstrictor Agents; Zona Glomerulosa | 2001 |
Suppression of Ca2+ influx through L-type voltage-dependent calcium channels by hydroxyl radical in mouse cerebral cortical neurons.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Calcium Signaling; Cells, Cultured; Cerebral Cortex; Deferoxamine; Ferrous Compounds; Free Radical Scavengers; Hydrogen Peroxide; Hydroxyl Radical; Ion Channel Gating; Ion Transport; Iron Chelating Agents; Mannitol; Mice; Nerve Tissue Proteins; Neurons; Nifedipine; omega-Agatoxin IVA; omega-Conotoxin GVIA; Potassium Chloride; Thiourea | 2001 |
Ca(2+) influx is increased in 2-kidney, 1-clip hypertensive rat aorta.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Aorta, Thoracic; Calcium; Calcium Channel Agonists; Dose-Response Relationship, Drug; Endothelium, Vascular; Hypertension, Renovascular; In Vitro Techniques; Male; Membrane Potentials; Muscle, Smooth, Vascular; Potassium Chloride; Rats; Rats, Wistar; Vasoconstriction | 2001 |
Gonadotropin subunit transcriptional responses to calcium signals in the rat: evidence for regulation by pulse frequency.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channel Agonists; Calcium Channels; Female; Follicle Stimulating Hormone; Follicle Stimulating Hormone, beta Subunit; Gene Expression Regulation; Gonadotropin-Releasing Hormone; Luteinizing Hormone; Periodicity; Pituitary Gland; Potassium Chloride; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Transcription, Genetic | 2001 |
Up-regulation of L-type voltage-dependent calcium channels after long term exposure to nicotine in cerebral cortical neurons.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Barium; Blotting, Western; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels, L-Type; Cells, Cultured; Cerebral Cortex; DNA, Complementary; Dose-Response Relationship, Drug; Electrophysiology; Enzyme Inhibitors; Ganglionic Stimulants; Immunoblotting; Kinetics; Mice; Neurons; Nicotine; Potassium Chloride; Protein Binding; RNA, Messenger; Time Factors; Up-Regulation; Verapamil | 2002 |
Diminished inibitory action of ethanol on the contraction of gallbladder isolated from chronically ethanol-fed Guinea pigs.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Body Weight; Calcium Channel Agonists; Dose-Response Relationship, Drug; Ethanol; Gallbladder; Guinea Pigs; Histamine; In Vitro Techniques; Male; Muscle Contraction; Phorbol 12,13-Dibutyrate; Potassium Chloride; Verapamil | 2002 |
Upregulation of L-type Ca2+ channels in mesenteric and skeletal arteries of SHR.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Blotting, Western; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels, L-Type; Dose-Response Relationship, Drug; Femoral Artery; Gene Expression; In Vitro Techniques; Mesenteric Arteries; Muscle, Skeletal; Muscle, Smooth, Vascular; Nifedipine; Potassium Chloride; Rats; Rats, Inbred SHR; Rats, Inbred WKY; RNA, Messenger; Up-Regulation; Vasoconstriction | 2002 |
Functional properties of ryanodine receptors in hippocampal neurons change during early differentiation in culture.
Topics: 3-Mercaptopropionic Acid; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Caffeine; Calcium; Calcium Channel Agonists; Calcium Channels, L-Type; Cell Differentiation; Cells, Cultured; Hippocampus; Neurons; Potassium Chloride; Rats; Rats, Sprague-Dawley; Ryanodine; Ryanodine Receptor Calcium Release Channel | 2002 |
Enhanced [Ca2+]i in renal arterial smooth muscle cells of pregnant rats with reduced uterine perfusion pressure.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Angiotensin II; Animals; Blood Pressure; Calcium; Calcium Channel Agonists; Culture Media; Female; Intracellular Membranes; Muscle, Smooth, Vascular; Osmolar Concentration; Potassium Chloride; Pregnancy; Pregnancy, Animal; Rats; Regional Blood Flow; Renal Artery; Uterus; Vasoconstriction | 2003 |
Insulin secretagogues, but not glucose, stimulate an increase in [Ca2+]i in the fetal human and porcine beta-cell.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channel Agonists; Cyclic AMP; Fetus; Glipizide; Glucose; Humans; In Vitro Techniques; Insulin; Insulin Secretion; Intracellular Membranes; Islets of Langerhans; Potassium Chloride; Swine | 2003 |
Analgesic action of loperamide, an opioid agonist, and its blocking action on voltage-dependent Ca2+ channels.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Analgesia; Analgesics; Animals; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels; Dose-Response Relationship, Drug; Drug Interactions; Extracellular Space; Fluorescent Dyes; Fura-2; Loperamide; Mice; Naloxone; Narcotic Antagonists; Pain; Pain Measurement; Posterior Horn Cells; Potassium Chloride | 2003 |
The effects of paroxetine on rat isolated vas deferens.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adenosine Triphosphate; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Electric Stimulation; Epididymis; Male; Muscle Contraction; Muscle, Smooth; Norepinephrine; Paroxetine; Potassium Chloride; Rats; Rats, Sprague-Dawley; Reserpine; Vas Deferens | 2003 |
Cotinine inhibits catecholamine release evoked by cholinergic stimulation from the rat adrenal medulla.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Acetylcholine; Adrenal Medulla; Animals; Catecholamines; Cotinine; Dimethylphenylpiperazinium Iodide; Dose-Response Relationship, Drug; Drug Administration Schedule; In Vitro Techniques; Indoles; Injections, Intravenous; Male; Nicotine; Potassium Chloride; Rats; Rats, Sprague-Dawley | 2003 |
Heat-shock response is associated with enhanced contractility of vascular smooth muscle in isolated rat aorta.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Androstadienes; Animals; Aorta, Thoracic; Calcium; Calcium Channel Agonists; Endothelium, Vascular; Heat-Shock Response; HSP70 Heat-Shock Proteins; Immunoblotting; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Myosin Light Chains; Myosin-Light-Chain Kinase; Phenylephrine; Phosphorylation; Potassium Chloride; Rats; Rats, Sprague-Dawley; Vasoconstrictor Agents; Wortmannin | 2004 |
Role of Ca2+ in vascular smooth muscle contractions induced by Phoneutria nigriventer spider venom.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channel Agonists; Chelating Agents; Egtazic Acid; Lanthanum; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Potassium Chloride; Rabbits; Spider Venoms | 2004 |
L-type voltage-gated Ca2+ channels modulate expression of smooth muscle differentiation marker genes via a rho kinase/myocardin/SRF-dependent mechanism.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Actins; Animals; Aorta; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Differentiation; Cells, Cultured; Gene Expression Profiling; Gene Expression Regulation, Developmental; Genes, fos; Intracellular Signaling Peptides and Proteins; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Myosin Heavy Chains; Nifedipine; Nuclear Proteins; Organoids; Patch-Clamp Techniques; Potassium Chloride; Protein Serine-Threonine Kinases; Protein Transport; Rats; Reverse Transcriptase Polymerase Chain Reaction; rho-Associated Kinases; rhoA GTP-Binding Protein; RNA, Small Interfering; Serum Response Element; Serum Response Factor; Trans-Activators; Transfection | 2004 |
Modulation of tracheal smooth muscle responses in inducible T-cell kinase knockout mice.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Acetylcholine; Animals; Calcium Channel Agonists; Carbachol; Cells, Cultured; Cholinergic Agonists; In Vitro Techniques; Isometric Contraction; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth; Neuromuscular Depolarizing Agents; Potassium Chloride; Protein-Tyrosine Kinases; Trachea | 2004 |
Defective calcium handling in cardiomyocytes isolated from hearts subjected to ischemia-reperfusion.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenergic beta-Agonists; Animals; Calcium; Calcium Channel Agonists; Catalase; Cell Survival; Hydrogen Peroxide; In Vitro Techniques; Ischemic Preconditioning, Myocardial; Isoproterenol; Male; Myocardial Reperfusion Injury; Myocytes, Cardiac; Oxidants; Oxidative Stress; Potassium Chloride; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta-1; Superoxide Dismutase; Ventricular Pressure | 2005 |
Functional inhibition of intestinal and uterine muscles by non-permeant triphenylethylene derivatives.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Acetylcholine; Animals; Calcium Channel Agonists; Calcium Chloride; Dose-Response Relationship, Drug; Duodenum; Estrogen Antagonists; Female; In Vitro Techniques; Male; Mice; Molecular Structure; Muscle Contraction; Potassium Channel Blockers; Potassium Chloride; Structure-Activity Relationship; Tamoxifen; Trityl Compounds; Uterus; Vasodilator Agents | 2006 |
Neuroprotective effects of ginseng saponins against L-type Ca2+ channel-mediated cell death in rat cortical neurons.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Apoptosis; Calcium Channel Blockers; Calcium Channels, L-Type; Cells, Cultured; Cerebral Cortex; Ginsenosides; Neurons; Neuroprotective Agents; Panax; Potassium Chloride; Rats; Rats, Sprague-Dawley; Saponins | 2008 |
Brazilein-induced contraction of rat arterial smooth muscle involves activation of Ca2+ entry and ROK, ERK pathways.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Aorta, Thoracic; Benzopyrans; Caesalpinia; Caffeine; Calcium; Diltiazem; Dose-Response Relationship, Drug; Extracellular Signal-Regulated MAP Kinases; In Vitro Techniques; Indenes; Male; Molecular Structure; Muscle Contraction; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nimodipine; Nitric Oxide Synthase; Phenylephrine; Pinacidil; Potassium Chloride; Rats; Rats, Wistar; rho-Associated Kinases; Signal Transduction; Vasoconstriction | 2008 |
Effects of adlay hull extracts on uterine contraction and Ca2+ mobilization in the rat.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Abortifacient Agents; Animals; Calcium; Calcium Channel Agonists; Chromatography, High Pressure Liquid; Coix; Dinoprost; Female; In Vitro Techniques; Methanol; Myocytes, Smooth Muscle; Plant Extracts; Potassium Chloride; Rats; Rats, Sprague-Dawley; Seeds; Solvents; Subcellular Fractions; Uterine Contraction | 2008 |
Isoflurane inhibits cyclic adenosine monophosphate response element-binding protein phosphorylation and calmodulin translocation to the nucleus of SH-SY5Y cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Active Transport, Cell Nucleus; Anesthetics, Inhalation; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels, L-Type; Calmodulin; Cell Line, Tumor; Cyclic AMP Response Element-Binding Protein; Dose-Response Relationship, Drug; Down-Regulation; Humans; Isoflurane; Membrane Potentials; Neuroblastoma; Neurons; Nitrendipine; omega-Conotoxin GVIA; Phosphorylation; Potassium Chloride; Time Factors | 2009 |
Screening for calcium channel modulators in CLN3 siRNA knock down SH-SY5Y neuroblastoma cells reveals a significant decrease of intracellular calcium levels by selected L-type calcium channel blockers.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Amlodipine; Blotting, Western; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line, Tumor; Child; Drug Evaluation, Preclinical; Flunarizine; Humans; Intracellular Space; Membrane Glycoproteins; Molecular Chaperones; Neuroblastoma; Neuronal Ceroid-Lipofuscinoses; Nicardipine; Nifedipine; Nimodipine; Potassium Chloride; RNA Interference; RNA, Small Interfering | 2011 |
NS-398 (a selective cyclooxygenase-2 inhibitor) decreases agonist-induced contraction of the human ureter via calcium channel inhibition.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adult; Calcium Channels; Cyclooxygenase 2 Inhibitors; Humans; In Vitro Techniques; Muscle Contraction; Muscle Relaxation; Nitrobenzenes; Potassium Chloride; Pyrazoles; Sulfonamides; Ureter | 2010 |
Disruption of K(2P)6.1 produces vascular dysfunction and hypertension in mice.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Aorta; Blood Pressure; Calcium Channel Agonists; Disease Models, Animal; Hypertension; Membrane Potentials; Mice; Mice, Knockout; Muscle, Smooth, Vascular; Potassium Channels, Tandem Pore Domain; Potassium Chloride; rho-Associated Kinases; Vasoconstriction; Vasoconstrictor Agents | 2011 |
Investigation of mechanisms involved in (-)-borneol-induced vasorelaxant response on rat thoracic aorta.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 4-Aminopyridine; Animals; Aorta, Thoracic; Calcium Chloride; Camphanes; Endothelium, Vascular; Glyburide; Phenylephrine; Potassium Channels; Potassium Chloride; Rats; Tetraethylammonium; Vasodilator Agents | 2012 |
Vasorelaxation, induced by Dictyota pulchella (Dictyotaceae), a brown alga, is mediated via inhibition of calcium influx in rats.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Biological Products; Calcium Channel Blockers; Calcium Channels; Dose-Response Relationship, Drug; Male; Muscle, Smooth, Vascular; Phaeophyceae; Phenylephrine; Potassium Chloride; Rats; Rats, Wistar; Tetraethylammonium; Vasodilation; Vasodilator Agents | 2011 |
Vasodilation and hypotension of CZ454, an analogue of lacidipine through inhibiting extracellular calcium influx.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Antihypertensive Agents; Blood Pressure; Caffeine; Calcium; Calcium Chloride; Calcium Signaling; Dihydropyridines; Hypotension; Male; Mesenteric Arteries; Muscle, Smooth, Vascular; Phenylephrine; Potassium; Potassium Chloride; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; Vasoconstriction; Vasodilation; Vasodilator Agents | 2012 |
Role of endothelium, acetylocholine and calcium ions in Bay K8644- and KCl-induced contraction.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Acetylcholine; Animals; Arteries; Calcium; Calcium Channel Agonists; Calcium Channels; Endothelium, Vascular; Guanylate Cyclase; Ions; Male; Muscle Contraction; Nitric Oxide Synthase; Nitroarginine; Oxadiazoles; Potassium Chloride; Quinoxalines; Rats; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; Soluble Guanylyl Cyclase | 2013 |
Antihypertensive and vasorelaxant effects of ethanol extract of stem barks from Zanthoxylum rhoifolium Lam. in rats.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Agonists; Calcium Channels; Calcium Chloride; Endothelium, Vascular; Ethanol; Male; Phenylephrine; Plant Bark; Plant Stems; Potassium Channels; Potassium Chloride; Rats; Rats, Inbred SHR; Rats, Wistar; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents; Zanthoxylum | 2013 |
L-type Ca²⁺ channel activity determines modulation of GABA release by dopamine in the substantia nigra reticulata and the globus pallidus of the rat.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Agatoxins; Analysis of Variance; Animals; Calcium Channel Agonists; Calcium Channels, L-Type; Dopamine; Dopamine Agents; gamma-Aminobutyric Acid; Globus Pallidus; In Vitro Techniques; Male; Nifedipine; Potassium Chloride; Rats; Rats, Wistar; Substantia Nigra; Tritium | 2014 |
Effects of dehydroeffusol on spasmogen-induced contractile responses of rat intestinal smooth muscles.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Histamine; Jejunum; Magnoliopsida; Male; Muscle Contraction; Muscle, Smooth; Parasympatholytics; Phenanthrenes; Pilocarpine; Plant Extracts; Potassium Chloride; Rats, Sprague-Dawley | 2014 |
Flavonoid galetin 3,6-dimethyl ether attenuates guinea pig ileum contraction through K(+) channel activation and decrease in cytosolic calcium concentration.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 4-Aminopyridine; Animals; Apamin; Calcium; Calcium Chloride; Carbachol; Cell Survival; Cesium; Chlorides; Flavonoids; Glyburide; Guinea Pigs; Histamine; Histamine Antagonists; Ileum; Muscle Cells; Muscle Contraction; Potassium Channel Blockers; Potassium Channels; Potassium Chloride; Tetraethylammonium | 2015 |
The inhibitor of connexin Cx36 channels, mefloquine, inhibits voltage-dependent Ca
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Action Potentials; Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Connexins; Dihydropyridines; Gap Junction delta-2 Protein; Glucose; Insulin Secretion; Insulin-Secreting Cells; Ion Channel Gating; Mefloquine; Mice; Nisoldipine; Potassium Chloride; Tolbutamide | 2018 |
Smooth muscle gap-junctions allow propagation of intercellular Ca
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Signaling; Endothelium, Vascular; Extracellular Space; Female; Gap Junctions; Male; Membrane Potentials; Mesenteric Arteries; Myocytes, Smooth Muscle; Potassium Channels; Potassium Chloride; Rats, Wistar; Vascular Resistance; Vasoconstriction | 2018 |
Pimpinella anisum extract attenuates spontaneous and agonist-induced uterine contraction in term-pregnant rats.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Carbachol; Female; Oxytocin; Pimpinella; Plant Extracts; Potassium Chloride; Pregnancy; Rats, Wistar; Tocolytic Agents; Uterine Contraction; Uterus | 2020 |