Compounds > porphobilinogen

porphobilinogen and phenobarbital

porphobilinogen has been researched along with phenobarbital in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-199010 (66.67)18.7374
1990's2 (13.33)18.2507
2000's1 (6.67)29.6817
2010's2 (13.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Atsmon, A; Epstein, O; Schoenfeld, N1
Percy, VA; Shanley, BC1
Atsmon, A; Mamet, R; Mevasser, R; Schoenfeld, N1
Piper, WN; Tephly, TR1
Becker, DM; Kramer, S; Viljoen, JD1
Frydman, B; Frydman, RB; Tomaro, ML1
Frydman, B; Frydman, RB; Tomaro, ML; Wanschelbaum, A1
De Matteis, F1
Bruinvels, J; Pepplinkhuizen, L; Schouten, MJ; Wilson, JH1
Atsmon, A; Epstein, O; Greenblat, Y; Lahav, M; Schoenfeld, N1
Fuchs, T; Ippen, H; Seubert, A; Seubert, S1
Buzaleh, AM; del Carmen Batlle, AM; Nuñez, G; Vazquez, ES1
Sykes, RM1
Berger, S; Chen, B; Desnick, RJ; Edelmann, W; Gama-Sosa, MA; Gan, L; Phillips, JD; Pollak, DD; Yasuda, M; Yu, C; Zhang, J1
Fontanellas, A; Jericó, D; Parra-Guillén, ZP; Sampedro, A; Serrano-Mendioroz, I; Trocóniz, IF; Vera-Yunca, D1

Other Studies

15 other study(ies) available for porphobilinogen and phenobarbital

ArticleYear
The effect of beta-adrenergic blocking agents on experimental porphyria induced by 3,5-diethoxycarbonyl-1,4-dihydrocollidine (DDC) in vivo and in vitro.
    Biochimica et biophysica acta, 1976, Aug-24, Volume: 444, Issue:1

    Topics: 5-Aminolevulinate Synthetase; Adrenergic beta-Antagonists; Aminolevulinic Acid; Animals; Chick Embryo; Dicarbethoxydihydrocollidine; Liver; Male; Phenobarbital; Porphobilinogen; Porphyrias; Porphyrins; Propranolol; Pyridines; Rats

1976
Lack of effect of phenobarbitone treatment on metabolism and brain uptake of delta-aminolaevulinic acid in rats.
    Biochemical pharmacology, 1977, Apr-15, Volume: 26, Issue:8

    Topics: Aminolevulinic Acid; Animals; Brain; Cytochrome P-450 Enzyme System; Female; Levulinic Acids; Liver; Phenobarbital; Porphobilinogen; Rats

1977
Experimental latent and acute porphyria in the non-fasted rat; preventive effect of propranolol.
    Scandinavian journal of clinical and laboratory investigation, 1991, Volume: 51, Issue:8

    Topics: Acute Disease; Allylisopropylacetamide; Aminolevulinic Acid; Animals; Coproporphyrins; Dicarbethoxydihydrocollidine; Feces; Male; Phenobarbital; Porphobilinogen; Porphyrias; Propranolol; Protoporphyrins; Rats; Rats, Inbred Strains

1991
The reversal of experimental porphyria and the prevention of induction of hepatic mixed-function oxidase by acetate.
    Archives of biochemistry and biophysics, 1974, Volume: 164, Issue:1

    Topics: 5-Aminolevulinate Synthetase; Acetates; Aminolevulinic Acid; Animals; Cytochrome c Group; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Dicarboxylic Acids; Enzyme Induction; Liver; Male; Microsomes, Liver; Mixed Function Oxygenases; Oxidoreductases; Phenobarbital; Porphobilinogen; Porphyrias; Porphyrins; Pyridines; Rats; Spectrophotometry; Sulfanilamides

1974
Delta-aminolevulinic acid uptake by rabbit brain cerebral cortex.
    Journal of neurochemistry, 1974, Volume: 23, Issue:5

    Topics: Allosteric Regulation; Amino Acids; Aminolevulinic Acid; Animals; Biological Transport, Active; Calcium; Carbon Radioisotopes; Cerebral Cortex; Cyanides; Dinitrophenols; In Vitro Techniques; Inulin; Ketoglutaric Acids; Kinetics; Levulinic Acids; Male; Osmolar Concentration; Ouabain; Phenobarbital; Porphobilinogen; Potassium; Rabbits; Sodium; Temperature; Time Factors

1974
Porphobilinogen oxygenase from rat liver: induction, isolation, and properties.
    Biochemistry, 1973, Dec-18, Volume: 12, Issue:26

    Topics: Allosteric Regulation; Animals; Chromatography, DEAE-Cellulose; Chromatography, Gel; Desoxycorticosterone; Enzyme Induction; Female; Hydrogen-Ion Concentration; Iron; Kinetics; Magnesium; Microsomes, Liver; Oxygenases; Phenobarbital; Porphobilinogen; Pregnenolone; Progesterone; Rats; Species Specificity; Structure-Activity Relationship; Temperature

1973
Porphobilinogen oxygenase: isolation and properties.
    Enzyme, 1973, Volume: 16, Issue:1

    Topics: Animals; Chromatography, DEAE-Cellulose; Chromatography, Gel; Chromatography, Ion Exchange; Chromatography, Thin Layer; Deoxycholic Acid; Digitonin; Enzyme Induction; Female; Kinetics; Magnetic Resonance Spectroscopy; Microsomes, Liver; Oxygenases; Phenobarbital; Porphobilinogen; Pregnenolone; Progesterone; Rats; Spectrophotometry; Spectrophotometry, Ultraviolet; Time Factors

1973
Drug interactions in experimental hepatic porphyria. A model for the exacerbation by drugs of human variegate porphyria.
    Enzyme, 1973, Volume: 16, Issue:1

    Topics: 5-Aminolevulinate Synthetase; Administration, Oral; Allylisopropylacetamide; Animals; Chickens; Cobalt; Dicarboxylic Acids; Dose-Response Relationship, Drug; Drug Synergism; Humans; Injections, Intraperitoneal; Levulinic Acids; Liver; Male; Mitochondria, Liver; Models, Biological; Phenobarbital; Porphobilinogen; Porphyrias; Pyridines; Rats; Species Specificity; Spectrometry, Fluorescence

1973
Serine and glycine-induced catalepsy in porphyric rats: an animal model for psychosis?
    Pharmacology, biochemistry, and behavior, 1983, Volume: 19, Issue:2

    Topics: Allylisopropylacetamide; Aminolevulinic Acid; Animals; Catalepsy; Disease Models, Animal; Glycine; Humans; Male; Phenobarbital; Porphobilinogen; Porphyrias; Psychotic Disorders; Rats; Rats, Inbred Strains; Serine

1983
Effect of prolonged fasting on heme metabolism in the rat.
    Israel journal of medical sciences, 1984, Volume: 20, Issue:3

    Topics: 5-Aminolevulinate Synthetase; Animals; Chromatography, Thin Layer; Fasting; Heme; Male; Phenobarbital; Porphobilinogen; Porphyrias; Rats; Rats, Inbred Strains

1984
Anticonvulsant-induced unclassified porphyria.
    The International journal of biochemistry, 1980, Volume: 12, Issue:5-6

    Topics: Adult; Aminolevulinic Acid; Anticonvulsants; Diagnosis, Differential; Epilepsy; Humans; Male; Phenobarbital; Phenytoin; Porphobilinogen; Porphyrias; Porphyrins

1980
Effect of chronic anesthesia on the drug-metabolizing enzyme system and heme pathway regulation.
    General pharmacology, 1997, Volume: 28, Issue:4

    Topics: 5-Aminolevulinate Synthetase; Aminolevulinic Acid; Anesthetics, Inhalation; Animals; Cytochrome P-450 Enzyme System; Enflurane; Heme; Hypnotics and Sedatives; Isoflurane; Liver; Male; Mice; Phenobarbital; Porphobilinogen; Porphyrins

1997
Acute intermittent porphyria, seizures, and antiepileptic drugs: a report on a 3-year-old Nigerian boy.
    Seizure, 2001, Volume: 10, Issue:1

    Topics: Anticonvulsants; Carbamazepine; Child, Preschool; Epilepsy, Generalized; Humans; Male; Phenobarbital; Porphobilinogen; Porphyria, Acute Intermittent; Severity of Illness Index

2001
Homozygous hydroxymethylbilane synthase knock-in mice provide pathogenic insights into the severe neurological impairments present in human homozygous dominant acute intermittent porphyria.
    Human molecular genetics, 2019, 06-01, Volume: 28, Issue:11

    Topics: Aminolevulinic Acid; Animals; Central Nervous System; Gene Knock-In Techniques; Genes, Dominant; Homozygote; Humans; Hydroxymethylbilane Synthase; Liver; Mice; Mutation, Missense; Myelin Sheath; Nervous System Diseases; Phenobarbital; Porphobilinogen; Porphyria, Acute Intermittent; Psychomotor Disorders

2019
Computational disease model of phenobarbital-induced acute attacks in an acute intermittent porphyria mouse model.
    Molecular genetics and metabolism, 2019, Volume: 128, Issue:3

    Topics: Aminolevulinic Acid; Animals; Computer Simulation; Disease Models, Animal; Male; Mice; Mice, Inbred C57BL; Phenobarbital; Porphobilinogen; Porphyria, Acute Intermittent; Porphyrins

2019