porphobilinogen has been researched along with aminolevulinic acid in 290 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 172 (59.31) | 18.7374 |
| 1990's | 50 (17.24) | 18.2507 |
| 2000's | 37 (12.76) | 29.6817 |
| 2010's | 23 (7.93) | 24.3611 |
| 2020's | 8 (2.76) | 2.80 |
| Authors | Studies |
|---|---|
| Scott, AI | 1 |
| Atsmon, A; Epstein, O; Schoenfeld, N | 1 |
| Eisenburg, J; Schmidt, M | 1 |
| Batlle, AM; Stella, AM; Wider de Xifra, EA | 1 |
| Bennett, M; Frykholm, BC; Lamon, JM; Tschudy, DP | 1 |
| Roots, LM | 1 |
| Brugsch, J; Müller, H | 1 |
| Brodie, MJ; Goldberg, A; Graham, DJ; McColl, KE; Moore, MR | 1 |
| Doss, M; Stutzer, H | 1 |
| Gidari, AS; Levere, RD | 1 |
| Becker, DM; Kramer, S | 1 |
| Doss, M | 2 |
| Druschky, KF; Schaller, KH; Schwanitz, G | 1 |
| Frykholm, BC; Herrera, W; Lamon, JM; Tschudy, DP | 1 |
| Armas Merino, R; Canals, C; Gómez, R; Monsalve, V; Wolff, C | 1 |
| Brodie, MJ; Goldberg, A; Hardie, RA; Hunter, JA; McColl, KE; Moore, MR; Thompson, GG | 1 |
| Wada, O | 1 |
| Bacheschi, LA; de Assis, JL; Do Serro-Azul, LG; Marchiori, PE; Moraes, EC; Scaff, M; Yassuda, N | 1 |
| Lithner, F | 1 |
| Lim, CK; Rideout, JM; Samson, DM | 1 |
| Ippen, H; Koransky, W; Koss, G; Seubert, A; Seubert, S | 1 |
| Frydman, RB; Tomaro, ML | 1 |
| Adjarov, D; Iwanov, ED; Tsanev, R | 1 |
| Astrup, EG | 1 |
| Gladyshev, BN; Liubchenko, PN; Mostun, VF | 1 |
| Edwards, PS; Pierach, CA | 1 |
| Dashman, T; Kamm, JJ | 1 |
| Desrochers, M; Sanderson, KE; Săsărman, A; Sonea, S; Surdeanu, M | 1 |
| Gardikas, C; Lyberatos, C; Mitsiou, C; Papadopoulos, N; Papasteriadis, E; Philippidou, A | 1 |
| Braun-Falco, O; Hofmann, C; Schmidt, D | 1 |
| Percy, VA; Shanley, BC | 2 |
| Neethling, AC; Percy, VA; Shanley, BC | 1 |
| Atuk, NO; Beal, MF; Turner, SM; Westfall, TC | 1 |
| Freye, HA; Wichmann, T | 1 |
| Bolsen, K; Goerz, G; Krieg, T | 1 |
| Bossenmaier, I; Cardinal, R; Peterson, A; Watson, CJ | 1 |
| Ross, J; Sautner, D | 1 |
| del Rio Anido, R; Garcia Devesa, J; Tutor Valcarce, JC | 1 |
| Chaudhry, AG; Jordan, PM | 1 |
| Doss, M; Schermuly, E | 1 |
| Nicoll, RA | 1 |
| Chartrand, P; Desrochers, M; Lapointe, C; Proschek, R; Săsărman, A; Tardif, D | 1 |
| Becker, DM; Goldstuck, N; Kramer, S; Loots, JM; Meyer, BJ | 1 |
| Frydman, B; Frydman, RB; Tomaro, ML; Wanschelbaum, A | 1 |
| de Klerk, M; Malan, C; Shanley, BC; Weideman, A | 1 |
| Bossenmaier, I; Cardinal, R; Dhar, GJ; Petryka, ZJ; Watson, CJ | 1 |
| Frederickson, EL; Mees, DE | 1 |
| Grandchamp, B; Grelier, M; Nordmann, Y | 1 |
| Kappas, A; Levere, RD; Sassa, S; Solish, G | 1 |
| Beattie, AD; Goldberg, A; Moore, MR; Paxton, JW | 1 |
| Murai, C | 1 |
| Alvares, AP; Anderson, KE; Kappas, A; Sassa, S | 1 |
| Dauner, HO; Gunzer, G; Heger, I; Müller, G | 1 |
| Mühler, E | 1 |
| Bonkowsky, HL; Collins, AR; Doherty, JM; Hess, RA; Magnussen, CR; Tschudy, DP | 1 |
| Eichenauer, MG; Goerz, G; Krieg, T | 1 |
| Bhattacharyya-Pakrasi, M; Daniels-McQueen, S; Goessling, LS; Lin, JJ; Thach, RE | 1 |
| Fässli, C; Haenel, A; Hänggi, W; Isenschmid, M; König, C; Schneider, H | 1 |
| Callebaut, B; Cornu, G; Hassoun, A; Ledoux, MC; Moos, B; Verstraeten, L | 1 |
| Marty, H | 1 |
| Akagi, R; Eberhart, CE; Prchal, JT; Sassa, S | 1 |
| el-Sharabasy, MM; el-Waseef, AM; Hafez, MM; Salim, SA | 1 |
| Floderus, Y; Henrichson, A; Meissner, P; Moore, MR; Sinclair, J; Thunell, S | 1 |
| Arena, A; Russo, P; Scuderi, D | 1 |
| Biel, AJ | 1 |
| Aldonatti, C; Cabral, JR; Cochón, AC; San Martín de Viale, LC; Wainstok de Calmanovici, R; Zenklusen, JC | 1 |
| Bonkovsky, HL; Gerron, GG; Healey, JF; Lourie, AN | 1 |
| Beckh, K; Doss, MO; Kersten, U; Sieg, I | 1 |
| Atsmon, A; Mamet, R; Mevasser, R; Schoenfeld, N | 2 |
| Doss, MO; Kandels, H; Schneider, J; Sieg, I | 1 |
| Brandys, J; Danek, M; Ignacak, J; Moniczewski, A | 1 |
| Goldberg, A; Herrick, AL; McColl, KE; Moore, MR; Wallace, AM | 1 |
| Anderson, KE; Bardin, CW; Kappas, A; Spitz, IM | 1 |
| Hift, R; Meissner, PN; Sohnius, U | 1 |
| Artner-Dworzak, E; Dierich, MP; Fuchs, D; Hausen, A; Reibnegger, G; Wachter, H; Werner, ER; Werner-Felmayer, G | 1 |
| Ho, JW | 1 |
| Aldonatti, C; San Martín de Viale, LC; Vila, MC | 1 |
| Adamson, AR; Brodie, MJ; Goldberg, A; Herrick, AL; McColl, KE; Moore, MR | 1 |
| Doss, MO; Frank, M | 1 |
| Grant, SK; Jordan, PM; Roessner, CA; Scott, AI; Stolowich, NJ; Warren, MJ; Williams, HJ | 1 |
| Cosloy, SD; Russell, CS; Umanoff, H | 1 |
| Jordan, PM; Warren, MJ | 1 |
| Bruinvels, J; Schouten, MJ | 1 |
| Jaffe, EK; Markham, GD | 1 |
| Brodie, MJ; Macphee, GJ; McGuire, GM; Moore, MR; Park, BK; Thompson, GG | 1 |
| Goldberg, A; Moore, MR; Yeung Laiwah, AC | 1 |
| Bissell, DM | 2 |
| Bonkovsky, HL; Healey, JF; Robinson, JM; Shedlofsky, SI; Sinclair, PR; Swim, AT | 1 |
| Fischer, JT; Goerz, G; Schneider, W; Wehmeier, A | 1 |
| Rosen, T; Sekula, SA; Tschen, JA | 1 |
| Holmberg, L; Lundgren, J; Thunell, S | 1 |
| Birnie, GG; Brodie, MJ; Goldberg, A; McColl, KE; Moore, MR; Thompson, GG | 1 |
| Arrol, S; Cutler, MG | 1 |
| Chan, KM; Kanan, R; Ladenson, JH; Vaidya, HC | 1 |
| Buchet, JP; Collart, F; Dratwa, M; Hassoun, A; Lauwerys, R; Tielemans, C; Wens, R | 1 |
| Wong, JD | 1 |
| Sasa, T; Shioi, Y | 1 |
| Akhtar, M; Jones, C | 1 |
| Alexopoulos, CG; Chalevelakis, G; Katsoulis, C; Pallikaris, G | 1 |
| Hanes, D; Jaffe, EK | 1 |
| Tishler, PV; Winston, SH | 2 |
| Abuaud Abo-Mohor, MC; Liberman, C; Olmos, S | 1 |
| Bolsen, K; Goerz, G; Merk, H | 1 |
| Kaada, B; Romslo, I | 1 |
| Doss, M; Sixel-Dietrich, F; Verspohl, F | 2 |
| Amantea, A; Anti, M; D'Alessandro Gandolfo, L; de Vitis, I; Fedeli, G; Griso, D; Rapaccini, GL; Topi, GC | 1 |
| Guthrie, R; Ho, J; Tieckelmann, H | 1 |
| Kwiatkowska, W; Nowojska, A; Zawirska, B | 1 |
| Gibbs, PN; Jordan, PM | 1 |
| Forret, CJ; Haines, DS; Haust, HL; Inwood, M; Keys, DS; O'Hea, EK; Poon, HC | 1 |
| Bernstein, M; Shivji, A | 1 |
| Siklósi, C; Simon, N | 1 |
| Aguilera, S; Rojas, F | 1 |
| Meyer, UA; Schmid, R | 1 |
| Piper, WN; Tephly, TR | 1 |
| Tomokuni, K | 1 |
| Pfändler, U | 1 |
| Cheesman, JO; Doherty, JM; Levine, JB; Magnussen, CR; Tschudy, DP | 1 |
| Bartlett, RS; Frier, HI; Hall, RC; Rousseau, JE | 1 |
| Becker, DM; Kramer, S; Viljoen, JD | 1 |
| Bhalla, KK; Torkington, P | 1 |
| Levin, EY | 1 |
| Kilian, M | 1 |
| Van Peteghem, T | 1 |
| Tschudy, DP; Watson, CJ | 1 |
| Lamm, MC; McCarthy, BW; Neethling, AC; Percy, VA; Taljaard, JJ; Truter, L | 1 |
| Lamm, MC; Russell, VA; Taljaard, JJ | 1 |
| Arsov, T; Ivanov, E | 1 |
| Friedland, ML; Ibraham, NG; Levere, RD | 1 |
| Bruinvels, J; Pepplinkhuizen, L; Schouten, MJ; Wilson, JH | 1 |
| Junor, B; Laiwah, AC; MacPhee, GJ; McColl, KE; Thompson, GG | 1 |
| Atchison, WD; Peterson, RE | 1 |
| Arsov, Ts; Gekova, K; Ivanov, E | 1 |
| Fukae, R; Sasa, T; Shioi, Y | 1 |
| Handa, F; Sidhu, KS; Verma, ML | 1 |
| Knosała, P; Petelenz, T; Zuk-Popiołek, I | 1 |
| Dall'Aglio, P; David, S; Savi, M | 1 |
| Noordhoek, KH; te Velde, K | 1 |
| Bonkowsky, HL; Schady, W | 1 |
| Bonkowsky, HL; Emery, S; Sinclair, JF; Sinclair, PR | 1 |
| Chang, KJ; Lin, SC; Lu, FJ; Tung, TC | 1 |
| Chang, KJ; Lee, TP; Lu, FJ; Tung, TC | 1 |
| Keithly, JH; Nadler, KD | 1 |
| Levy, M; Unikowsky, B | 1 |
| Goldberg, A; Laiwah, AC; Moore, MR | 1 |
| Gordon, BJ; Tishler, PV | 1 |
| O'Connor, LJ | 1 |
| Hensley, WJ; Stewart, PM | 1 |
| Goerz, G; Krieg, T; Lissner, R; Sick, N; Vizethum, W | 1 |
| Romeo, G | 1 |
| Kappas, A; Sassa, S | 1 |
| Waldenström, J | 1 |
| Goldberg, A; McColl, KE; Moore, MR; Thompson, GG; Wallace, AM | 1 |
| Day, RS; Eales, L | 1 |
| Abdullaev, GM; Baĭtaeva, DA; Safarov, IuI | 1 |
| Adam, C; Defresne, C; Guilmot-Bruneau, M; Hassoun, A; Saussez-De Temmerman, A; Wery-Follet, B | 1 |
| El-Waseef, A | 1 |
| Crowne, H; Lim, CK; Samson, D | 1 |
| Smit, EM; Westerhof, W | 1 |
| Mustajoki, P | 1 |
| Ganda, C; Joshi, P; Kramer, S | 1 |
| Bonkowsky, HL; Healey, JF; Sinclair, JF; Sinclair, PR | 1 |
| Gregor, A; Kostrzewska, E; Lipska-Koziołowa, H; Traczyk, A | 1 |
| San Martin de Viale, LC; Wainstok de Calmanovici, R | 1 |
| Lockwood, WH; Poulos, V | 1 |
| Bannerman, RM; El-Khatib, M; Franco-Saenz, R; Kreimer-Birnbaum, M | 1 |
| Batlle, AM; Malamud, S; Stella, AM; Wider de Xifra, EA | 1 |
| Doss, M; Schneider, J; von Tiepermann, R | 1 |
| Batlle, AM; Kesten, EM; Stella, AM; Wider de Xifra, EA | 1 |
| Fuchs, T; Ippen, H; Seubert, A; Seubert, S | 1 |
| Avramenko, MM; Gladyshev, BN; Liubchenko, PN; Ostrum, IuZ | 1 |
| Böhrer, H; Bolsen, K; Goerz, G; Lux, R; Martin, E; Schmidt, H | 1 |
| Bhutani, LK; Doss, MO; Sieg, I | 1 |
| Enriquez de Salamanca, R; Hernandez, A; Moran, MJ; Sepulveda, P | 1 |
| Daume, E; Doss, MO; Düsterberg, B; Frank, M; Gross, U; Honcamp, M | 1 |
| Urata, G | 1 |
| Kondo, M | 2 |
| Horie, Y; Kawasaki, H; Nanba, E; Norimoto, M; Sasaki, H; Tajima, F | 1 |
| Elcock, D; Norris, A | 1 |
| Dover, SB; McColl, KE; Moore, MR; Plenderleith, L | 1 |
| Amato, S; Gullotti, D; Salerno, L; Schillaci, L | 1 |
| Bach, A; Böhrer, H; Bolsen, K; Goerz, G; Kohl, B; Martin, E; Schmidt, H | 1 |
| Gregor, A; Kostrzewska, E; Stachurska, H; Tarczynska-Nosal, S | 1 |
| Cutler, M; Dover, S; Moore, MR; Odber, J | 1 |
| Braverman, S; Helson, L; Mangiardi, J | 1 |
| Badcock, NR; O'Reilly, DA; Parker, CJ; Robertson, EF; Zoanetti, GD | 1 |
| Del C Batlle, AM; Guolo, M; Melito, V; Parera, V; Stella, AM | 1 |
| Ellefson, RD; Ford, RE | 1 |
| Flageul, B; Janier, M; Mouly, F; Nordmann, Y | 1 |
| Deka, J; Lim, CK; Luo, JL | 1 |
| Buzaleh, AM; del Carmen Batlle, AM; Nuñez, G; Vazquez, ES | 1 |
| Deybach, JC; Lamoril, J; Martasek, P; Nordmann, Y; Puy, H; Rosipal, R | 1 |
| Böhrer, H; Bolsen, K; Fritsch, C; Goerz, G; Kalka, K; Rominger, KL | 1 |
| Kondo, M; Yano, Y | 1 |
| de Bruin, RW; de Rooij, FW; Edixhoven-Bosdijk, A; Houtsmuller, AB; Siersema, PD; Tilanus, HW; van den Boogert, J; van Hillegersberg, R; Wilson, JH | 1 |
| Asirvatham, SJ; Jackman, WM; Johnson, TW; Oberoi, MP | 1 |
| de Pauw, BE; Schattenberg, AV | 1 |
| Hift, RJ | 1 |
| Adachi, K; Horie, Y; Kawasaki, H; Kondo, M; Kudo, Y; Maeda, N; Nanba, E; Sasaki, Y; Ueta, E | 1 |
| Lim, CK; Lord, GA; Luo, JL | 1 |
| Bobálová, J; Henz, ME; Jarret, C; Lüönd, RM; Marty, M; Neier, R; Schürmann, P; Stauffer, F | 1 |
| Batlle, A; Garcia, SC; Moretti, MB | 1 |
| de Rooij, FW; Edixhoven, A; Hinnen, P; Siersema, PD; Terlouw, EM; Tilanus, HW; van Dekken, H; van Hillegersberg, R; Wilson, JH | 1 |
| Doss, MO; Gross, U; Kühnel, A | 1 |
| Kimura, S; Shibuki, K; Wakatsuki, H | 1 |
| Kim, JN; Ryu, HW; Yun, JS | 1 |
| Bobálová, J; Engeloch-Jarret, C; Faurite, JP; Neier, R; Stauffer, F; Zizzari, E | 1 |
| Biel, AJ; Canada, K; Huang, D; Indest, K; Sullivan, K | 1 |
| Kauppinen, R; von und zu Fraunberg, M | 1 |
| Araujo, LS; Batlle, A; Lombardo, ME | 1 |
| Andersson, C; Dahlquist, G; Hultdin, J; Schmauch, A; Wikberg, A | 1 |
| Weykamp, CW; Willems, HL; Zuijderhoudt, FM | 1 |
| Goodwin, CE; Leeper, FJ | 1 |
| Edixhoven, A; Gabeler, EE; Schoonderwoerd, K; Sluiter, W; Statius van Eps, RG; van Hillegersberg, R; van Urk, H | 1 |
| DRESEL, EI; FALK, JE | 1 |
| GRANICK, S; MAUZERALL, D | 1 |
| WITH, TK | 1 |
| ABBOTT, LD; JAMES, GW; RUDOLPH, SG | 1 |
| GUTNIAK, O; KRAWCZYK, I | 1 |
| DANCEWICZ, AM | 1 |
| DE KRETSER, AJ; WALDRON, HA | 1 |
| KIEHN, BP; SCHLENKER, FS; TAYLOR, NA | 1 |
| MARKLE, V; PAZDER, LH; TAYLOR, JD | 1 |
| GRANICK, S; VANDEN SCHRIECK, HG | 1 |
| JANOUSEK, V; OCENASEK, M | 1 |
| SANO, S; SUMIYA, C; TANABE, Y | 1 |
| ARATO, G; BUDA, V; KELENYI, G; ORBAN, S | 1 |
| HIGHTOWER, NC; MALOOLY, DA | 1 |
| MOREO, L; SAITA, G | 1 |
| Warholm, C; Wilczek, H | 1 |
| Chandler, G; Deacon, AC; Macdougall, IC; Marsden, JT; Peters, TJ; Winkler, AS | 1 |
| Hift, RJ; Kirsch, RE; Meissner, PN; Todd, G | 1 |
| Beaumont, N; Deacon, A; Laftah, AH; Peters, TJ; Raja, KB; Simpson, RJ; Solanky, N; Srai, SK | 1 |
| Akagi, R; Doss, MO; Doss-Frank, M; Gross, U; Renz, M; Sassa, S; Seelig, HP; Stauch, T | 1 |
| Kayser, H; Krull-Savage, U; Rilk-van Gessel, R | 1 |
| Herrick, AL; McColl, KE | 1 |
| Andersson, C; Andersson, DE; Floderus, Y; Harper, P; Möller, C; Rejkjaer, L; Sardh, E | 1 |
| Aarsand, AK; Petersen, PH; Sandberg, S | 1 |
| Andersson, DE; Harper, P; Rejkjaer, L; Sardh, E | 1 |
| Chuang, WL; Huang, CC; Kuo, HC; Lee, MJ | 1 |
| Brekke, OL; Nielsen, EW; Storjord, E | 1 |
| Karpova, IV; Kravshenko, SK; Kremenetskaia, AM; Luchinina, IuA; Luk'ianenko, AV; Pustovoĭt, IaS; Surin, VL | 1 |
| Bloomer, JR; McGuire, BM | 1 |
| Jayakumar, M; Manorajan, R; Prabahar, MR; Sathiyakumar, D; Soundararajan, P | 1 |
| Laftah, AH; Peters, TJ; Raja, KB; Simpson, RJ | 1 |
| Billoo, AG; Lone, SW | 1 |
| Farbstein, I; Luder, AS; Mamet, R; Schoenfeld, N | 1 |
| Andersson, DE; Harper, P; Henrichson, A; Sardh, E | 1 |
| Andersson, DE; Floderus, Y; Harper, P; Sardh, E | 1 |
| Brancaleoni, V; Cappellini, MD; Di Pierro, E; Ferrari, MC; Marchini, S; Moriondo, V; Nascimbeni, F; Rocchi, E; Tavazzi, D; Ventura, P | 1 |
| de Salamanca, RE; Dubrot, J; Fontanellas, A; González-Aseguinolaza, G; Mauleón, I; Melero, I; Prieto, J; Sampedro, A; Unzu, C; Vanrell, L | 1 |
| Aguilera, L; Tébar, MT | 1 |
| Aarsand, AK; Lindberg, M; Sandberg, S; Sandvik, AK; Skadberg, Ø; Webber, PR | 1 |
| Choiniere, JR; Gelb, MH; Scott, CR; Turecek, F | 1 |
| Brancaleoni, V; Cappellini, MD; Di Pierro, E; Graziadei, G; Tavazzi, D | 1 |
| Bushnell, EA; Erdtman, E; Eriksson, LA; Gauld, JW | 1 |
| Bouizegarene, P; da Silva, VP; Deybach, JC; Puy, H | 1 |
| Balwani, M; Bishop, D; Desnick, RJ; Yasuda, M; Yu, C; Zhang, J | 1 |
| Czarnecki, O; Grimm, B; Peter, E | 1 |
| Chu, CC; Chuang, WL; Huang, CC; Kuo, HC; Lee, MJ; Liu, CY; Ning, HC; Wu, CL; Wu, T | 1 |
| Benton, CM; Jones, DJ; Lim, CK; Moniz, C | 1 |
| Benton, CM; Couchman, L; Lim, CK; Marsden, JT; Moniz, C; Rees, DC | 2 |
| Fujita, H | 1 |
| Ellis, EC; Ericzon, BG; Harper, P; Nowak, G; Wahlin, S; Yin, Z | 1 |
| Akyay, A; Arda, K; Bal, C; Biçakçi, Z; Erdemli, E; Hazirolan, T; Kaymak-Cihan, M; Olcay, L; Oztürkmen, S; Terzi, YK; Yildirmak, Y | 1 |
| Marsden, JT; Rees, DC | 1 |
| Deybach, JC; François, A; Gouya, L; Karim, Z; Karras, A; Mami, I; Nochy, D; Pallet, N; Puy, H; Rabant, M; Schmitt, C; Thervet, E; Xu-Dubois, Y | 1 |
| Anderson, KE; Arvelakis, A; Balwani, M; Chen, B; Clavero, S; Desnick, RJ; Erwin, AL; Fiel, MI; Florman, SS; Gan, L; Gordon, RE; Kadirvel, S; Liu, LU; Martin, LD; Naik, H; Phillips, JD; Sadagoparamanujam, VM; Yasuda, M; Yu, C | 1 |
| Chandrashaker, V; Lindsey, JS; Ptaszek, M; Taniguchi, M | 1 |
| Brekke, OL; Dahl, JA; Karlsen, BO; Karlsen, MB; Landsem, A; Ludviksen, JK; Storjord, E | 1 |
| Berger, S; Chen, B; Desnick, RJ; Edelmann, W; Gama-Sosa, MA; Gan, L; Phillips, JD; Pollak, DD; Yasuda, M; Yu, C; Zhang, J | 1 |
| Fontanellas, A; Jericó, D; Parra-Guillén, ZP; Sampedro, A; Serrano-Mendioroz, I; Trocóniz, IF; Vera-Yunca, D | 1 |
| Doss, MO; Schuppan, D; Stölzel, U | 1 |
| Agarwal, S; Clausen, VA; Goel, V; Habtemariam, BA; Kim, JB; Robbie, GJ; Simon, AR | 1 |
| Anderson, KE; Balwani, M; Bissell, DM; Bonkovsky, HL; Chen, J; Garg, P; Gouya, L; Harper, P; Horie, Y; Ivanova, A; Kauppinen, R; Keel, SB; Kim, JB; Ko, JJ; Langendonk, JG; Liu, S; Minder, E; Parker, C; Peiró, PA; Penz, C; Phillips, J; Rees, DC; Sardh, E; Silver, SM; Simon, AR; Stein, PE; Stölzel, U; Sweetser, MT; Vaishnaw, A; Vassiliou, D; Ventura, P; Wang, B; Wang, JD; Windyga, J | 1 |
| Adzajlic, S; Barakovic, A; Brigic, A; Cerovac, A; Softic, D | 1 |
| Comentale, G; Manzo, R; Pilato, E | 1 |
| Córdoba, KM; Ena, J; Enríquez de Salamanca, R; Fontanellas, A; Jericó, D; Morales-Conejo, M; Solares, I | 1 |
| Balwani, M; Bonkovsky, HL; Lim, JK; Wang, B | 1 |
| Dessendier, N; Gouya, L; Junot, C; Lefebvre, T; Manceau, H; Moulouel, B; Nguyen, AL; Poli, A; Puy, H; Schmitt, C; Talbi, N | 1 |
| Floderus, Y; Harper, P; Lissing, M; Sardh, E; Vassiliou, D; Wahlin, S; Wester, A | 1 |
27 review(s) available for porphobilinogen and aminolevulinic acid
| Article | Year |
|---|---|
Tests available for assessing recent exposure to inorganic lead compounds and their use for screening purposes.
Topics: 5-Aminolevulinate Synthetase; Aminolevulinic Acid; Cholinesterases; Edetic Acid; Erythrocytes; Feces; Glucosephosphate Dehydrogenase; Hair; Hemoglobinometry; Humans; Lead; Methods; Porphobilinogen; Porphobilinogen Synthase; Porphyrins; Sodium-Potassium-Exchanging ATPase; Staining and Labeling; Tooth; Zinc | 1979 |
Enzymatic formation and cellular regulation of heme synthesis.
Topics: 5-Aminolevulinate Synthetase; Aminolevulinic Acid; Animals; Coenzyme A; Coproporphyrinogens; Enzyme Induction; Heme; Humans; Liver; Porphobilinogen; Porphobilinogen Synthase; Porphyrias; Protoporphyrins; Uroporphyrinogens | 1977 |
The neurological manifestations of porphyria: a review.
Topics: Acute Disease; Aminolevulinic Acid; Animals; Heme; Humans; Liver; Liver Diseases; Nervous System; Neurologic Manifestations; Peripheral Nerves; Porphobilinogen; Porphyrias; Porphyrins | 1977 |
[Pathobiochemistry of porphyrias].
Topics: Acute Disease; Aminolevulinic Acid; Catalase; Chronic Disease; Cytochrome P-450 Enzyme System; Heme; Humans; Liver; Liver Diseases; Porphobilinogen; Porphyrias; Porphyrins; Protoporphyrins | 1977 |
[Chromosome studies in patients with intermittent porphyria].
Topics: Adult; Aminolevulinic Acid; Chromosome Aberrations; Female; Heme; Humans; Hydroxymethylbilane Synthase; Male; Middle Aged; Pedigree; Porphobilinogen; Porphyrias | 1979 |
[Porphyria variegata (author's transl)].
Topics: Adult; Aminolevulinic Acid; Coproporphyrins; Erythrocytes; Feces; Female; Hand; Humans; Lip; Porphobilinogen; Porphyrias; Porphyrins; Protoporphyrins; Uroporphyrins | 1975 |
[Selected biochemical indicators of the effect of environmental lead on the humans].
Topics: Abattoirs; Adult; Air Pollutants; Air Pollutants, Occupational; Aminolevulinic Acid; Chemical Industry; Erythrocytes; Glutathione; Humans; Lead; Lead Poisoning; Metallurgy; Middle Aged; Poland; Porphobilinogen; Urban Population | 1991 |
Pathogenesis of acute porphyria.
Topics: Acute Disease; Aminolevulinic Acid; Animals; Heme; Humans; Nervous System; Porphobilinogen; Porphyrias | 1987 |
Intermittent acute porphyria: the enzymatic defect.
Topics: 5-Aminolevulinate Synthetase; Adenosine Triphosphatases; Alanine; Aminolevulinic Acid; Ammonia-Lyases; Dysautonomia, Familial; Heme; Humans; Liver; Porphobilinogen; Porphyrias; Porphyrins | 1974 |
[Value of biological test for the detection of increased lead uptake in man].
Topics: Aminolevulinic Acid; Body Burden; Environmental Exposure; Erythrocyte Count; Erythrocytes; Erythropoiesis; Hair; Hemoglobins; Humans; Lead; Lead Poisoning; Occupational Diseases; Porphobilinogen; Porphyrins | 1974 |
Heme metabolism in erythroid and hepatic cells.
Topics: 5-Aminolevulinate Synthetase; Aminolevulinic Acid; Coproporphyrinogen Oxidase; Erythrocytes; Erythropoiesis; Ferrochelatase; Flavoproteins; Heme; Heme Oxygenase (Decyclizing); Humans; Liver; Liver Diseases; Mitochondrial Proteins; Oxidoreductases; Oxidoreductases Acting on CH-CH Group Donors; Porphobilinogen; Porphobilinogen Synthase; Porphyrias; Protoporphyrinogen Oxidase; Skin Diseases; Uroporphyrinogen Decarboxylase; Uroporphyrinogen III Synthetase | 1983 |
Laboratory evaluation in porphyria.
Topics: Acute Disease; Aminolevulinic Acid; Animals; Carrier State; Chemistry, Clinical; Diagnosis, Differential; Erythrocytes; Feces; Humans; Hydroxymethylbilane Synthase; Isomerism; Porphobilinogen; Porphyrias; Porphyrins; Protoporphyrins; Skin Diseases | 1982 |
Neurologic manifestations of acute porphyria.
Topics: Acute Disease; Aminolevulinic Acid; Animals; Central Nervous System; Depression; Electrophysiology; gamma-Aminobutyric Acid; Glycine; Heme; Humans; Light; Liver Diseases; Muscle Hypotonia; Nerve Fibers; Nerve Fibers, Myelinated; Nervous System Diseases; Pain, Intractable; Peripheral Nerves; Porphobilinogen; Porphobilinogen Synthase; Porphyrias; Prognosis; Seizures; Vitamin B 6 Deficiency; Zinc | 1982 |
The hepatic porphyrias.
Topics: 5-Aminolevulinate Synthetase; Acute Disease; Adolescent; Adult; Aminolevulinic Acid; Chemical Phenomena; Chemistry; Child; Child, Preschool; Female; Gene Expression Regulation; Heme; Humans; Infant; Liver; Liver Diseases; Male; Middle Aged; Photosensitivity Disorders; Porphobilinogen; Porphyria, Acute Intermittent; Porphyrias; Porphyrias, Hepatic; Porphyrins; Prenatal Diagnosis; Protoporphyria, Erythropoietic; Recurrence; Skin Diseases | 1980 |
Genetic, metabolic, and biochemical aspects of the porphyrias.
Topics: Aminolevulinic Acid; Animals; Cat Diseases; Cats; Cattle; Cattle Diseases; Erythrocytes; Heme; Humans; Liver; Porphobilinogen; Porphobilinogen Synthase; Porphyrias; Porphyrinogens; Porphyrins; Rodent Diseases; Sciuridae; Swine; Swine Diseases | 1981 |
The porphyrias--a review.
Topics: Acute Disease; Aged; Alcoholism; Aminolevulinic Acid; Feces; Female; Heme; Humans; Iron; Liver Diseases; Male; Porphobilinogen; Porphyrias; Skin Diseases; Time Factors | 1981 |
[The chemistry of porphyrins and their precursors on the heme biosynthetic chain].
Topics: Aminolevulinic Acid; Heme; Humans; Porphobilinogen; Porphyrins; Uroporphyrinogens | 1995 |
[Methods of determination of porphyrins and their precursors--introduction of analytical methods for porphyrin metabolites].
Topics: Aminolevulinic Acid; Chromatography; Chromatography, Thin Layer; Electrophoresis; Humans; Porphobilinogen; Porphyrias; Porphyrins; Spectrophotometry | 1995 |
[Porphyrins in urine, blood, and feces and delta-aminolevulinic acid and porphobilinogen].
Topics: Aminolevulinic Acid; Chromatography, High Pressure Liquid; Diagnosis, Differential; Feces; Humans; Porphobilinogen; Porphyrias; Porphyrins | 1995 |
The porphyrias [corrected]: characteristics and laboratory tests.
Topics: Aminolevulinic Acid; Environmental Exposure; Feces; Humans; Porphobilinogen; Porphyrias; Porphyrins | 1996 |
[Hereditary coproporphyria (HCP)].
Topics: Aminolevulinic Acid; Biomarkers; Diagnosis, Differential; Mutation; Porphobilinogen; Porphobilinogen Synthase; Porphyrias, Hepatic; Prognosis | 1998 |
[Perplexing acute or chronic somatic or psychiatric symptoms: possibly due to porphyria].
Topics: Abdominal Pain; Adult; Aminolevulinic Acid; Disease Management; Female; Humans; Laparotomy; Mental Disorders; Netherlands; Porphobilinogen; Porphyria, Acute Intermittent; Precipitating Factors; Recurrence; Ultrasonography; Unnecessary Procedures | 1998 |
Acute intermittent porphyria.
Topics: Abdominal Pain; Adult; Aminolevulinic Acid; Cytochrome P-450 Enzyme System; Erythrocytes; Female; Heme; Humans; Porphobilinogen; Porphyria, Acute Intermittent | 2005 |
Porphyrias at a glance: diagnosis and treatment.
Topics: Acute Disease; Aminolevulinic Acid; Chronic Disease; Genetic Testing; Heme; Humans; Porphobilinogen; Porphyrias; Porphyrins | 2010 |
Clinical Guide and Update on Porphyrias.
Topics: Aminolevulinic Acid; Gastroenterology; Gastrointestinal Diseases; Humans; Nervous System Diseases; Porphobilinogen; Porphyrias; Porphyrins; Practice Guidelines as Topic; Skin Diseases | 2019 |
Understanding Carbohydrate Metabolism and Insulin Resistance in Acute Intermittent Porphyria.
Topics: Aminolevulinic Acid; Animals; Carbohydrate Metabolism; Glucose; Heme; Humans; Hydroxymethylbilane Synthase; Insulin; Insulin Resistance; Mice; Porphobilinogen; Porphyria, Acute Intermittent | 2022 |
AGA Clinical Practice Update on Diagnosis and Management of Acute Hepatic Porphyrias: Expert Review.
Topics: Abdominal Pain; Aminolevulinic Acid; Antiemetics; Carcinoma, Hepatocellular; Creatinine; Female; Heme; Hemin; Humans; Hypertension; Liver Neoplasms; Middle Aged; Porphobilinogen; Porphobilinogen Synthase; Porphyria, Acute Intermittent; Porphyrias, Hepatic; Quality of Life; Renal Insufficiency, Chronic; United States | 2023 |
7 trial(s) available for porphobilinogen and aminolevulinic acid
| Article | Year |
|---|---|
Erythropoietin treatment in the neuropsychiatric porphyrias.
Topics: Adult; Aged; Aminolevulinic Acid; Erythropoietin; Female; Hematologic Tests; Hemoglobins; Humans; Male; Mental Disorders; Middle Aged; Porphobilinogen; Porphyrias; Porphyrins | 2003 |
Administration of oral activated charcoal in variegate porphyria results in a paradoxical clinical and biochemical deterioration.
Topics: Administration, Oral; Adolescent; Adult; Aminolevulinic Acid; Analysis of Variance; Charcoal; Female; Humans; Male; Porphobilinogen; Porphyrias, Hepatic; Porphyrins; Prospective Studies; South Africa; Treatment Failure | 2003 |
Safety, pharmacokinetics and pharmocodynamics of recombinant human porphobilinogen deaminase in healthy subjects and asymptomatic carriers of the acute intermittent porphyria gene who have increased porphyrin precursor excretion.
Topics: Adult; Aged; Aminolevulinic Acid; Antibody Formation; Area Under Curve; Chromatography, Liquid; Dose-Response Relationship, Drug; Double-Blind Method; Enzyme-Linked Immunosorbent Assay; Female; Heterozygote; Humans; Hydroxymethylbilane Synthase; Male; Mass Spectrometry; Middle Aged; Porphobilinogen; Porphyria, Acute Intermittent | 2007 |
Plasma porphobilinogen as a sensitive biomarker to monitor the clinical and therapeutic course of acute intermittent porphyria attacks.
Topics: Acute Disease; Adult; Aminolevulinic Acid; Arginine; Biomarkers; Chromatography, Ion Exchange; Drug Monitoring; Female; Glucose; Heme; Humans; Male; Porphobilinogen; Porphyria, Acute Intermittent; Sensitivity and Specificity | 2009 |
Biochemical, radiologic, ultrastructural, and genetic evaluation of iron overload in acute leukemia and iron-chelation therapy.
Topics: Adolescent; Aminolevulinic Acid; Bone Marrow; Bone Marrow Cells; Child; Female; Ferritins; Hemochromatosis; Humans; Iron; Iron Chelating Agents; Leukemia, Myeloid, Acute; Lysosomes; Male; Mutation, Missense; Porphobilinogen; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 2014 |
Pharmacokinetics and Pharmacodynamics of the Small Interfering Ribonucleic Acid, Givosiran, in Patients With Acute Hepatic Porphyria.
Topics: Acetylgalactosamine; Adult; Aminolevulinic Acid; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Half-Life; Humans; Injections, Subcutaneous; Male; Middle Aged; Porphobilinogen; Porphyria, Acute Intermittent; Pyrrolidines; Young Adult | 2020 |
Phase 3 Trial of RNAi Therapeutic Givosiran for Acute Intermittent Porphyria.
Topics: Acetylgalactosamine; Adult; Aminolevulinic Acid; Double-Blind Method; Fatigue; Female; Humans; Injections, Subcutaneous; Least-Squares Analysis; Liver; Male; Nausea; Pain; Patient Outcome Assessment; Porphobilinogen; Porphyria, Acute Intermittent; Pyrrolidines; Renal Insufficiency, Chronic; RNAi Therapeutics; Transaminases | 2020 |
256 other study(ies) available for porphobilinogen and aminolevulinic acid
| Article | Year |
|---|---|
The biosynthesis of vitamin B12.
Topics: Aminolevulinic Acid; Models, Chemical; Porphobilinogen; Propionibacterium; S-Adenosylmethionine; Stereoisomerism; Uroporphyrinogens; Vitamin B 12 | 1976 |
The effect of beta-adrenergic blocking agents on experimental porphyria induced by 3,5-diethoxycarbonyl-1,4-dihydrocollidine (DDC) in vivo and in vitro.
Topics: 5-Aminolevulinate Synthetase; Adrenergic beta-Antagonists; Aminolevulinic Acid; Animals; Chick Embryo; Dicarbethoxydihydrocollidine; Liver; Male; Phenobarbital; Porphobilinogen; Porphyrias; Porphyrins; Propranolol; Pyridines; Rats | 1976 |
[A new method for the clinical determination of urinary porphobilinogen and delta-aminolevulinic acid].
Topics: Aminolevulinic Acid; Electrolytes; Humans; Hydrogen-Ion Concentration; Levulinic Acids; Methods; Porphobilinogen | 1977 |
A simple method for measuring erythrocyte porphobilinogenase, and its use in the diagnosis of acute intermittent porphyria.
Topics: Aminolevulinic Acid; Ammonia-Lyases; Erythrocytes; Hemolysis; Humans; Hydrogen-Ion Concentration; Porphobilinogen; Porphyrias; Spectrophotometry | 1978 |
Prevention of acute porphyric attacks by intravenous haematin.
Topics: Acute Disease; Adult; Aminolevulinic Acid; Blood Pressure; Circadian Rhythm; Drug Evaluation; Female; Heme; Hemin; Humans; Infusions, Parenteral; Menstruation; Porphobilinogen; Porphyrias; Pulse; Remission, Spontaneous | 1978 |
[Urinary excretion of porphyrins and their precursors. Longterm observations in acute intermittent porphyrias (author's transl)].
Topics: Aminolevulinic Acid; Coproporphyrins; Estrogens; Humans; Porphobilinogen; Porphyrias; Porphyrins; Uroporphyrinogens; Uroporphyrins | 1979 |
Quantitation of 3-ethyl-5-hydroxy-4,5-dimethyl-delta 3-pyrrolin-2-one in the urine of patients with acute intermittent porphyria.
Topics: Acute Disease; Adult; Aminolevulinic Acid; Chromatography, Gas; Female; Heme; Humans; Porphobilinogen; Porphyrias; Pyrroles | 1979 |
[Letter: Comments and conclusion to H. Stutzer: Typical and atypical roentgen pictures in the acute porphyria. Fortschr. Röntgenstr. 123,6 (1975) 588-590].
Topics: Abdomen, Acute; Acute Disease; Aminolevulinic Acid; Diagnosis, Differential; Female; Humans; Middle Aged; Porphobilinogen; Porphyrias | 1976 |
Danazol administration to females with menses-associated exacerbations of acute intermittent porphyria.
Topics: Adult; Aminolevulinic Acid; Danazol; Female; Hemin; Humans; Menstruation; Porphobilinogen; Porphyrias; Pregnadienes | 1979 |
[Effect of hematin in acute porphyric relapse].
Topics: Acute Disease; Adult; Aminolevulinic Acid; Coproporphyrins; Heme; Hemin; Humans; Male; Porphobilinogen; Porphyrias; Uroporphyrins | 1979 |
Haem biosynthesis in cutaneous hepatic porphyria: comparison with alcoholism and liver disease.
Topics: 5-Aminolevulinate Synthetase; Aminolevulinic Acid; Coproporphyrins; Erythrocytes; Ferrochelatase; Heme; Humans; Hydroxymethylbilane Synthase; Leukocytes; Liver Diseases, Alcoholic; Male; Porphobilinogen; Porphobilinogen Synthase; Porphyrias; Uroporphyrinogen Decarboxylase | 1979 |
[Laboratory diagnosis of anomalies of porphyrin metabolism].
Topics: Aminolevulinic Acid; Humans; Methods; Porphobilinogen; Porphyrias; Porphyrins | 1979 |
[Hematin treatment of acute intermittent porphyria. A case report (author's transl)].
Topics: Adolescent; Aminolevulinic Acid; Antihypertensive Agents; Electromyography; Female; Heme; Hemin; Humans; Infusions, Parenteral; Lung; Porphobilinogen; Porphyrias | 1979 |
[Acute intermittent porphyria--a clinical review].
Topics: Acute Disease; Aminolevulinic Acid; Diagnosis, Differential; Heme; Humans; Porphobilinogen; Porphyrias | 1979 |
Determination of 5-aminolaevulinic acid and porphobilinogen by high-performance liquid chromatography.
Topics: Aminolevulinic Acid; Animals; Chromatography, High Pressure Liquid; Erythrocytes; Levulinic Acids; Porphobilinogen; Porphobilinogen Synthase; Porphyrias | 1979 |
Studies on the toxicology of hexachlorobenzene. III. Observations in a long-term experiment.
Topics: Aminolevulinic Acid; Animals; Chlorobenzenes; Female; Hexachlorobenzene; Kinetics; Organ Size; Porphobilinogen; Porphyrins; Rats; Time Factors | 1978 |
Porphobilinogen oxygenase induction by 2-allyl-2-isopropylacetamide treatment.
Topics: 5-Aminolevulinate Synthetase; Acetamides; Allylisopropylacetamide; Aminolevulinic Acid; Animals; Enzyme Induction; Female; Microsomes, Liver; Mixed Function Oxygenases; Oxidoreductases; Porphobilinogen; Rats | 1977 |
[Uroporphyrinogen-I-synthetase in erythrocytes in acute intermittent porphyria].
Topics: Adolescent; Aminolevulinic Acid; Ammonia-Lyases; Bulgaria; Erythrocytes; Female; Humans; Hydroxymethylbilane Synthase; Male; Pedigree; Porphobilinogen; Porphyria, Acute Intermittent; Porphyrias | 1977 |
Family studies on the activity of uroporphyrinogen I synthase in diagnosis of acute intermittent porphyria.
Topics: Adolescent; Adult; Aged; Aminolevulinic Acid; Ammonia-Lyases; Clinical Enzyme Tests; Female; Humans; Hydroxymethylbilane Synthase; Male; Middle Aged; Pedigree; Porphobilinogen; Porphyrias | 1978 |
[Porphobilinogen biosynthesis from delta-aminolevulinic acid by the internal organs of white rats].
Topics: Aminolevulinic Acid; Animals; Depression, Chemical; In Vitro Techniques; Kidney; Lead; Levulinic Acids; Liver; Lung; Male; Organ Specificity; Porphobilinogen; Rats | 1978 |
Relationships between acute hepatic porphyrias due to genetic variability of primary enzyme defects and limiting function of uroporphyrinogen synthase.
Topics: 5-Aminolevulinate Synthetase; Acute Disease; Adolescent; Adult; Aged; Aminolevulinic Acid; Ammonia-Lyases; Coproporphyrinogen Oxidase; Coproporphyrins; Female; Humans; Hydroxymethylbilane Synthase; Liver; Male; Middle Aged; Porphobilinogen; Porphyrias; Porphyrins; Protoporphyrins; Uroporphyrinogen III Synthetase | 1978 |
Neurotoxicity of delta-aminolevulinic acid and porphobilinogen.
Topics: Aminolevulinic Acid; Animals; Brain; Dose-Response Relationship, Drug; Injections, Intraventricular; Levulinic Acids; Male; Movement; Porphobilinogen; Rats; Seizures | 1978 |
Inhibition of delta-aminolevulinic acid synthetase and delta-aminolevulinic acid dehydrase by L-2-amino-4-methoxy-trans-3-butenoic acid in the rat.
Topics: 5-Aminolevulinate Synthetase; Aminobutyrates; Aminolevulinic Acid; Animals; Anti-Bacterial Agents; In Vitro Techniques; Liver; Male; Mitochondria, Liver; Porphobilinogen; Porphobilinogen Synthase; Porphyrins; Rats | 1979 |
Porphobilinogen-accumulating mutants of Salmonella typhimurium LT2.
Topics: Aminolevulinic Acid; Catalase; Cell-Free System; Chromosome Mapping; Conjugation, Genetic; Genes; Hydroxymethylbilane Synthase; Mutation; Porphobilinogen; Porphyrins; Salmonella typhimurium; Transduction, Genetic | 1976 |
Urine porphyrins and their precursors in homozygous beta-thalassaemia.
Topics: Adolescent; Adult; Aminolevulinic Acid; Child; Child, Preschool; Coproporphyrins; Female; Homozygote; Humans; Male; Porphobilinogen; Porphyrins; Thalassemia; Uroporphyrins | 1975 |
Lack of effect of phenobarbitone treatment on metabolism and brain uptake of delta-aminolaevulinic acid in rats.
Topics: Aminolevulinic Acid; Animals; Brain; Cytochrome P-450 Enzyme System; Female; Levulinic Acids; Liver; Phenobarbital; Porphobilinogen; Rats | 1977 |
Pathogenesis of neural manifestations in acute porphyria.
Topics: 5-Aminolevulinate Synthetase; Acute Disease; Aminolevulinic Acid; Animals; Anura; Brain; Heme; Humans; In Vitro Techniques; Mice; Neurologic Manifestations; Porphobilinogen; Porphyrias; Rats | 1977 |
Prophyrin precursors in blood, urine and cerebrospinal fluid in acute porphyria.
Topics: Acute Disease; Adult; Aminolevulinic Acid; Female; Humans; Middle Aged; Porphobilinogen; Porphyrias; Porphyrinogens | 1977 |
Catecholamine uptake, accumulation, and release in acute porphyria.
Topics: Acute Disease; Adolescent; Adult; Aminolevulinic Acid; Animals; Blood Platelets; Catecholamines; Erythrocytes; Female; Humans; Hydroxymethylbilane Synthase; In Vitro Techniques; Male; Middle Aged; Myocardium; Norepinephrine; Porphobilinogen; Porphyrias; Potassium Chloride; Rats | 1977 |
[Pathophysiology and diagnosis of acute intermittent porphyria].
Topics: Acute Disease; Aminolevulinic Acid; Erythrocytes; Humans; Hydroxymethylbilane Synthase; Porphobilinogen; Porphyrias; Porphyrins | 1977 |
[Letter: Porphyria cutanea tarda: normalization of porphyrin-excretion following treatment with p-amino-benzoic acid (Potaba) (author's transl)].
Topics: Adult; Aminobenzoates; Aminolevulinic Acid; Female; Humans; Middle Aged; Porphobilinogen; Porphyrias; Porphyrins | 1976 |
Hematin treatment of acute porphyria. Early remission of an almost fatal relapse.
Topics: Acute Disease; Adult; Aminolevulinic Acid; Female; Follow-Up Studies; Heme; Hemin; Humans; Infusions, Parenteral; Porphobilinogen; Porphyrias; Remission, Spontaneous | 1976 |
Induction of globin mRNA accumulation by hemin in cultured erythroleukemic cells.
Topics: Aminolevulinic Acid; Biliverdine; Cell Line; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Erythropoiesis; Globins; Heme; Hemin; Hemoglobins; Kinetics; Porphobilinogen; RNA, Messenger; RNA, Neoplasm | 1976 |
Letter: Possible mechanism of the interference of porphobilinogen in the direct determination of urinary delta-aminolevulinic acid.
Topics: Aminolevulinic Acid; Chemical Phenomena; Chemistry; Evaluation Studies as Topic; Hot Temperature; Levulinic Acids; Porphobilinogen | 1976 |
Stereochemical studies on the formation of porphobilinogen.
Topics: Aminolevulinic Acid; Animals; Carbon Radioisotopes; Cattle; Hydro-Lyases; Isotope Labeling; Liver; Methods; Porphobilinogen; Porphobilinogen Synthase; Tritium | 1976 |
Porphyrin biosynthesis from ALA and PBG by human erythrocytes in porphyrin disorders. Kinetic studies of the isomer series I and III.
Topics: Aminolevulinic Acid; Coproporphyrins; Erythrocytes; Hot Temperature; Humans; Isomerism; Kinetics; Levulinic Acids; Porphobilinogen; Porphyrias; Porphyrins; Protoporphyrins; Uroporphyrins | 1976 |
The interaction of porphyrin precursors with GABA receptors in the isolated frog spinal cord.
Topics: Aminobutyrates; Aminolevulinic Acid; Animals; gamma-Aminobutyric Acid; In Vitro Techniques; Levulinic Acids; Membrane Potentials; Motor Neurons; Porphobilinogen; Rana pipiens; Receptors, Drug; Spinal Cord | 1976 |
Uroporphyrin-accumulating mutant of Escherichia coli K-12.
Topics: Acetates; Aminolevulinic Acid; Catalase; Cell-Free System; Chromosome Mapping; Cyclohexanones; Escherichia coli; Genes; Hydroxymethylbilane Synthase; Mutation; Neomycin; Porphobilinogen; Porphyrins; Solvents; Stereoisomerism; Transduction, Genetic; Uroporphyrinogen Decarboxylase; Uroporphyrinogens; Uroporphyrins | 1975 |
The effect of porphyrin precursors on monosynaptic reflex activity in the isolated hemisected frog spinal cord.
Topics: Aminolevulinic Acid; Animals; Depression, Chemical; Evoked Potentials; In Vitro Techniques; Levulinic Acids; Neural Conduction; Porphobilinogen; Reflex, Monosynaptic; Sciatic Nerve; Seasons; Spinal Cord; Spinal Nerve Roots; Xenopus | 1975 |
Porphobilinogen excretion in chemical induced porphyria: reversal by induction of porphobilinogen oxygenase.
Topics: Acetamides; Allylisopropylacetamide; Aminolevulinic Acid; Animals; Enzyme Induction; Fasting; Liver; Oxygenases; Porphobilinogen; Porphyrias; Pregnenolone; Rats; Time Factors | 1975 |
Urinary porphyrins and porphyrin precursors in normal pregnancy. Relationship to urinary total oestrogen excretion,.
Topics: Aminolevulinic Acid; Coproporphyrins; Creatinine; Estrogens; Female; Humans; Porphobilinogen; Porphyrins; Postpartum Period; Pregnancy; Pregnancy Trimester, Third; Uroporphyrins | 1975 |
Effects of hematin in hepatic porphyria. Further studies.
Topics: Adult; Aminolevulinic Acid; Female; Heme; Hemin; Humans; Infusions, Parenteral; Liver; Male; Middle Aged; Porphobilinogen; Porphyrias; Porphyrins; Recurrence | 1975 |
Anesthesia and the porphyrias.
Topics: 5-Aminolevulinate Synthetase; Acute Disease; Aminolevulinic Acid; Ammonia-Lyases; Anesthesia; Anesthetics; Child; Chlordiazepoxide; Cytochrome P-450 Enzyme System; Demyelinating Diseases; Diazepam; Heme; Humans; Neostigmine; Pentazocine; Porphobilinogen; Porphyrias; Thiopental | 1975 |
[Acute intermittent porphyria. Detection of asymptomatic carriers of the genetic defect].
Topics: Acute Disease; Adolescent; Adult; Aged; Aminolevulinic Acid; Ammonia-Lyases; Child; Child, Preschool; Coproporphyrins; Erythrocytes; Female; Humans; Hydroxymethylbilane Synthase; Infant; Male; Middle Aged; Porphobilinogen; Porphyrias; Uroporphyrins | 1975 |
Studies in porphyria. IV. Expression of the gene defect of acute intermittent porphyria in cultured human skin fibroblasts and amniotic cells: prenatal diagnosis of the porphyric trait.
Topics: Abortion, Induced; Adolescent; Adult; Aminolevulinic Acid; Ammonia-Lyases; Amniocentesis; Amniotic Fluid; Cells, Cultured; Erythrocytes; Female; Fibroblasts; Genes; Humans; Hydroxymethylbilane Synthase; Infant; Male; Middle Aged; Porphobilinogen; Porphyrias; Porphyrins; Pregnancy; Prenatal Diagnosis; Skin; Time Factors | 1975 |
Urinary excretion of 17-oxosteroids in hereditary coproporphyria.
Topics: 17-Ketosteroids; Adult; Aminolevulinic Acid; Androsterone; Coproporphyrins; Etiocholanolone; Female; Glucuronates; Humans; Male; Middle Aged; Porphobilinogen; Porphyrias; Porphyrins; Sulfates | 1975 |
[Experimental studies on porphyrin metabolism in heavy metal poisoning. (I) Studies on the urinary excretion of porphyrin and its precusor in experimental lead poisoned rats related to the dose response (author's transl)].
Topics: Aminolevulinic Acid; Animals; Coproporphyrins; Dose-Response Relationship, Drug; Lead Poisoning; Male; Porphobilinogen; Porphyrins; Rats | 1975 |
Studies in porphyria. V. Drug oxidation rates in hereditary hepatic porphyria.
Topics: Adult; Aminolevulinic Acid; Antipyrine; Erythrocytes; Female; Half-Life; Humans; Hydroxymethylbilane Synthase; Kinetics; Liver Diseases; Male; Middle Aged; Oxidation-Reduction; Phenylbutazone; Porphobilinogen; Porphyrias | 1976 |
[On uroporphyrinogen formation: Studies with 1-aminomethyl-3, 8, 13, 18-tetra(2-carboxyethyl)-2, 7, 12, 17-tetracarboxymethylbilinogen (author's transl)].
Topics: Aminolevulinic Acid; Clostridium; Hydroxymethylbilane Synthase; Porphobilinogen; Propionibacterium; Uroporphyrinogen III Synthetase; Uroporphyrinogens; Vitamin B 12 | 1976 |
[Diagnostic and therapeutic problems in acute intermittent porphyria].
Topics: Acute Disease; Adrenal Cortex Hormones; Adult; Aminolevulinic Acid; Analgesics; Colic; Color; Diagnosis, Differential; Female; Humans; Medication Errors; Middle Aged; Polyneuropathies; Porphobilinogen; Porphyrias; Prognosis; Psychotic Disorders; Vitamin B Complex; Vitamins | 1976 |
Comparative effects of glycerol and dextrose on porphyrin precursor excretion in acute intermittent porphyria.
Topics: Acute Disease; Adolescent; Adult; Aged; Aminolevulinic Acid; Dietary Carbohydrates; Dietary Fats; Female; Glucose; Glucose Tolerance Test; Glycerol; Growth Hormone; Humans; Insulin; Levulinic Acids; Male; Porphobilinogen; Porphyrias; Porphyrins | 1976 |
[Accident in treatment of porphyria cutanea tarda by chloroquine (Resochin) (author's transl)].
Topics: Aminolevulinic Acid; Chloroquine; Humans; Liver; Male; Medication Errors; Middle Aged; Mitochondria, Liver; Porphobilinogen; Porphyrias; Porphyrins | 1976 |
Enhanced degradation of the ferritin repressor protein during induction of ferritin messenger RNA translation.
Topics: 5-Aminolevulinate Synthetase; Aminolevulinic Acid; Animals; Cell Line; Cell Line, Transformed; Ferritins; Fibroblasts; Iron; Iron Regulatory Protein 1; Iron-Regulatory Proteins; Mice; Papillomaviridae; Porphobilinogen; Protein Biosynthesis; Rabbits; RNA-Binding Proteins; RNA, Messenger | 1992 |
[Acute intermittent porphyria in pregnancy: glucose or hematin therapy?].
Topics: Acute Disease; Adult; Aminolevulinic Acid; Drug Therapy, Combination; Female; Glucose Solution, Hypertonic; Hemin; Humans; Porphobilinogen; Porphyrias; Pregnancy; Pregnancy Complications | 1992 |
Interference of Tienam in colorimetric determination of 5-aminolevulinic acid and porphobilinogen in serum and urine.
Topics: Aminolevulinic Acid; Child; Colorimetry; False Positive Reactions; Humans; Imipenem; Male; Porphobilinogen | 1992 |
[What is your diagnosis? Acute intermittent porphyria].
Topics: Adult; Aminolevulinic Acid; Female; Humans; Porphobilinogen; Porphyrias; Porphyrins; Postoperative Complications | 1992 |
An acquired acute hepatic porphyria: a novel type of delta-aminolevulinate dehydratase inhibition.
Topics: Acute Disease; Aminolevulinic Acid; Blotting, Western; Colorimetry; Dithiothreitol; Humans; Male; Middle Aged; Porphobilinogen; Porphobilinogen Synthase; Porphyrias, Hepatic | 1992 |
Porphyrin metabolism in some malignant diseases.
Topics: Adult; Aminolevulinic Acid; Child; Coproporphyrins; Erythrocytes; Female; Ferrochelatase; Heme; Hodgkin Disease; Humans; Hydroxymethylbilane Synthase; Lymphoma, Non-Hodgkin; Male; Porphobilinogen; Porphobilinogen Synthase; Porphyrins; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Uroporphyrins | 1992 |
Alcoholic beverages in acute porphyria.
Topics: Acute Disease; Alcoholic Beverages; Aminolevulinic Acid; Dose-Response Relationship, Drug; Genetic Carrier Screening; Humans; Phenotype; Porphobilinogen; Porphyrias; Risk Factors | 1992 |
Acute intermittent porphyria. A perplexing case.
Topics: Acute Disease; Aminolevulinic Acid; Female; Humans; Middle Aged; Nervous System Diseases; Pain; Porphobilinogen; Porphyrias | 1992 |
Oxygen-regulated steps in the Rhodobacter capsulatus tetrapyrrole biosynthetic pathway.
Topics: Aminolevulinic Acid; Bacteriochlorophylls; Oxygen; Porphobilinogen; Protoporphyrins; Pyrroles; Rhodobacter capsulatus; Tetrapyrroles | 1992 |
Influence of hepatic tumors caused by diethylnitrosamine on hexachlorobenzene-induced porphyria in rats.
Topics: 5-Aminolevulinate Synthetase; Aminolevulinic Acid; Animals; Carcinoma, Hepatocellular; Cytochrome P-450 Enzyme System; Diethylnitrosamine; Female; Ferrochelatase; Hexachlorobenzene; Liver; Liver Neoplasms; Porphobilinogen; Porphyrias; Porphyrins; Rats | 1991 |
Intravenous heme-albumin in acute intermittent porphyria: evidence for repletion of hepatic hemoproteins and regulatory heme pools.
Topics: Acute Disease; Adult; Aminolevulinic Acid; Analysis of Variance; Cytochrome P-450 Enzyme System; Female; Hemin; Humans; Hydroxyindoleacetic Acid; Infusions, Intravenous; Kynurenine; Liver; Middle Aged; Porphobilinogen; Porphyrias; Porphyrins; Serum Albumin; Tryptophan | 1991 |
Manifestation of acute intermittent porphyria in patients with chronic inflammatory bowel disease.
Topics: Acute Disease; Adolescent; Adult; Aminolevulinic Acid; Colitis, Ulcerative; Crohn Disease; Humans; Porphobilinogen; Porphyrias; Porphyrins; Risk Factors | 1991 |
Experimental latent and acute porphyria in the non-fasted rat; preventive effect of propranolol.
Topics: Acute Disease; Allylisopropylacetamide; Aminolevulinic Acid; Animals; Coproporphyrins; Dicarbethoxydihydrocollidine; Feces; Male; Phenobarbital; Porphobilinogen; Porphyrias; Propranolol; Protoporphyrins; Rats; Rats, Inbred Strains | 1991 |
Effect of alcohol on delta-aminolevulinic acid dehydratase and porphyrin metabolism in man.
Topics: Adult; Alcoholism; Aminolevulinic Acid; Coproporphyrins; Dithiothreitol; Erythrocytes; Ethanol; Female; Humans; Male; Middle Aged; Models, Biological; Porphobilinogen; Porphobilinogen Synthase; Porphyrins; Reference Values; Zinc | 1991 |
Elevation of hormone-binding globulins in acute intermittent porphyria.
Topics: Adolescent; Adult; Aminolevulinic Acid; Arginine; Carrier Proteins; Heme; Humans; Hydrocortisone; Liver Diseases; Porphobilinogen; Porphyrias; Prospective Studies; Sex Hormone-Binding Globulin; Testosterone; Thyroxine-Binding Proteins | 1990 |
A gonadotropin releasing hormone analogue prevents cyclical attacks of porphyria.
Topics: Adult; Aminolevulinic Acid; Female; Gonadotropin-Releasing Hormone; Humans; Menstrual Cycle; Periodicity; Porphobilinogen; Porphyrias | 1990 |
Safety of vancomycin in acute porphyria.
Topics: Acute Disease; Adult; Aminolevulinic Acid; Erythrocytes; Female; Humans; Hydroxymethylbilane Synthase; Porphobilinogen; Porphyrias; Sepsis; Staphylococcal Infections; Vancomycin | 1990 |
Urinary excretion of porphyrins is increased in patients with HIV-1 infection.
Topics: Acquired Immunodeficiency Syndrome; Adolescent; Adult; Aminolevulinic Acid; Biopterins; Female; HIV Seropositivity; Humans; Immunity, Cellular; Levulinic Acids; Male; Metabolic Clearance Rate; Middle Aged; Neopterin; Porphobilinogen; Porphyrins; Substance Abuse, Intravenous | 1990 |
Micro assay for urinary delta-aminolevulinic acid and porphobilinogen by high-performance liquid chromatography with pre-column derivatization.
Topics: Aminolevulinic Acid; Chromatography, High Pressure Liquid; Humans; Levulinic Acids; Microchemistry; o-Phthalaldehyde; Porphobilinogen | 1990 |
[Evaluation of porphyrinogenic effect of lindane in rats].
Topics: 5-Aminolevulinate Synthetase; Aminolevulinic Acid; Animals; Heme; Hexachlorocyclohexane; Levulinic Acids; Liver; Male; Porphobilinogen; Porphyrias; Porphyrins; Rats; Rats, Inbred Strains | 1986 |
Acute intermittent porphyria in two patients on anticonvulsant therapy and with normal erythrocyte porphobilinogen deaminase activity.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Ammonia-Lyases; Anticonvulsants; Erythrocytes; Female; Humans; Hydroxymethylbilane Synthase; Male; Middle Aged; Phenytoin; Porphobilinogen; Porphyrias; Valproic Acid | 1989 |
Hepatobiliary implications and complications in protoporphyria, a 20-year study.
Topics: Adult; Aminolevulinic Acid; Child, Preschool; Chromatography, Ion Exchange; Chromatography, Thin Layer; Feces; Female; Humans; Liver Diseases; Longitudinal Studies; Male; Middle Aged; Porphobilinogen; Porphyrias; Porphyrins; Protoporphyrins; Sex Factors; Spectrophotometry | 1989 |
Identification of a cysteine residue as the binding site for the dipyrromethane cofactor at the active site of Escherichia coli porphobilinogen deaminase.
Topics: Aminolevulinic Acid; Ammonia-Lyases; Binding Sites; Carbon Radioisotopes; Chemical Phenomena; Chemistry; Cysteine; Escherichia coli; Hydrogen-Ion Concentration; Hydroxymethylbilane Synthase; Magnetic Resonance Spectroscopy; Porphobilinogen | 1988 |
Availability of porphobilinogen controls appearance of porphobilinogen deaminase activity in Escherichia coli K-12.
Topics: Aminolevulinic Acid; Ammonia-Lyases; Enzyme Induction; Escherichia coli; Hemin; Hydroxymethylbilane Synthase; Porphobilinogen | 1988 |
Investigation into the nature of substrate binding to the dipyrromethane cofactor of Escherichia coli porphobilinogen deaminase.
Topics: Aminolevulinic Acid; Ammonia-Lyases; Binding Sites; Catalysis; Chromatography, High Pressure Liquid; Coenzymes; Escherichia coli; Hydroxymethylbilane Synthase; Kinetics; Mutation; Porphobilinogen; Pyridoxal Phosphate; Sulfhydryl Reagents | 1988 |
Endogenously formed norharman (beta-carboline) in platelet rich plasma obtained from porphyric rats.
Topics: Alkaloids; Allylisopropylacetamide; Aminolevulinic Acid; Animals; Blood Platelets; Carbolines; Catalepsy; Glycine; Harmine; Male; Porphobilinogen; Porphyrias; Rats; Rats, Inbred Strains; Serine | 1986 |
13C NMR studies of methylene and methine carbons of substrate bound to a 280,000-dalton protein, porphobilinogen synthase.
Topics: Aminolevulinic Acid; Carbon; Deuterium; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Molecular Weight; Porphobilinogen; Porphobilinogen Synthase; Schiff Bases; Solvents | 1988 |
The effects of chronic carbamazepine treatment of haem biosynthesis in man and rat.
Topics: 5-Aminolevulinate Synthetase; Adolescent; Adult; Aged; Aminolevulinic Acid; Ammonia-Lyases; Animals; Carbamazepine; Female; Heme; Humans; Hydroxymethylbilane Synthase; Leukocytes; Male; Middle Aged; Porphobilinogen; Porphobilinogen Synthase; Porphyrins; Rats; Rats, Inbred Strains | 1988 |
Treatment of acute hepatic porphyria with hematin.
Topics: Acute Disease; Adult; Aged; Aminolevulinic Acid; Female; Heme; Hemin; Humans; Liver Diseases; Male; Middle Aged; Porphobilinogen; Porphyrias | 1988 |
Haem synthesis from exogenous 5-aminolaevulinate in cultured chick-embryo hepatocytes. Effects of inducers of cytochromes P-450.
Topics: Allylisopropylacetamide; Aminolevulinic Acid; Animals; Cells, Cultured; Chick Embryo; Cytochrome P-450 Enzyme System; Deferoxamine; Enzyme Induction; Heme; Levulinic Acids; Liver; Methylcholanthrene; Porphobilinogen; Porphyrins | 1987 |
Polychemotherapy of acute myelogenous leukemia in a patient with acute intermittent porphyria.
Topics: Acute Disease; Adult; Aminolevulinic Acid; Antineoplastic Combined Chemotherapy Protocols; Chemical and Drug Induced Liver Injury; Doxorubicin; Female; Humans; Leukemia, Myeloid, Acute; Liver Diseases; Mitolactol; Porphobilinogen; Porphyrias; Porphyrins; Risk; Tamoxifen | 1987 |
The porphyrias.
Topics: Adolescent; Adult; Aminolevulinic Acid; beta Carotene; Bloodletting; Carotenoids; Child; Child, Preschool; Chloroquine; Humans; Infant; Liver Diseases; Male; Middle Aged; Porphobilinogen; Porphyrias; Skin; Skin Diseases; Skin Diseases, Vesiculobullous; Sunlight; Uroporphyrins | 1986 |
Aminolaevulinate dehydratase porphyria in infancy. A clinical and biochemical study.
Topics: Aminolevulinic Acid; Erythrocytes; Female; Humans; Infant, Newborn; Kinetics; Male; Pedigree; Porphobilinogen; Porphobilinogen Synthase; Porphyrias; Porphyrins | 1987 |
Antipyrine metabolism in acute hepatic porphyria in relapse and remission.
Topics: 5-Aminolevulinate Synthetase; Adolescent; Adult; Aged; Aminolevulinic Acid; Antipyrine; Cytochrome P-450 Enzyme System; Female; Humans; Liver Diseases; Male; Metabolic Clearance Rate; Middle Aged; Mixed Function Oxygenases; Porphobilinogen; Porphyrias; Porphyrins | 1987 |
Pharmacological effects of haem biosynthetic intermediates in isolated intestinal preparations.
Topics: Aminolevulinic Acid; Animals; Colon; Coproporphyrins; Female; Glycine; Heme; Hemin; In Vitro Techniques; Intestinal Mucosa; Intestines; Jejunum; Male; Muscle Contraction; Porphobilinogen; Protoporphyrins; Rabbits; Succinates | 1987 |
Washington University case conference. Dual porphyria--an underdiagnosed entity?
Topics: Aminolevulinic Acid; Coproporphyrins; Diagnosis, Differential; Feces; Flavoproteins; Humans; Male; Middle Aged; Mitochondrial Proteins; Oxidoreductases; Oxidoreductases Acting on CH-CH Group Donors; Porphobilinogen; Porphyrias; Protoporphyria, Erythropoietic; Protoporphyrinogen Oxidase; Skin Diseases; Uroporphyrinogen Decarboxylase; Uroporphyrins | 1987 |
Effect of aluminum on porphyrin metabolism in hemodialyzed patients.
Topics: Adult; Aged; Aluminum; Aminolevulinic Acid; Female; Humans; Hydroxymethylbilane Synthase; Male; Middle Aged; Porphobilinogen; Porphobilinogen Synthase; Porphyrins; Protoporphyrins; Renal Dialysis | 1987 |
Porphyrin test as an alternative to benzidine test for detecting cytochromes in catalase-negative gram-positive cocci.
Topics: Aminolevulinic Acid; Catalase; Cytochromes; Gram-Positive Bacteria; Micrococcaceae; Porphobilinogen; Porphyrins; Streptococcaceae | 1987 |
Isotachophoretic analysis of porphyrin precursors: 5-aminolevulinic acid derivatives.
Topics: Aminolevulinic Acid; Electrophoresis; Levulinic Acids; Porphobilinogen; Valerates | 1986 |
Preparation of stereospecifically labeled porphobilinogens.
Topics: Aminolevulinic Acid; Glycine; Ketoglutaric Acids; Molecular Conformation; Porphobilinogen; Stereoisomerism; Succinates; Succinic Acid | 1986 |
Adverse effect of cis-diamminedichloroplatinum II (CDDP) on porphyrin metabolism in man.
Topics: Adolescent; Adult; Aged; Aminolevulinic Acid; Blood Cell Count; Cisplatin; Coproporphyrins; Female; Hematocrit; Humans; Male; Middle Aged; Porphobilinogen; Porphyrins; Uroporphyrins | 1986 |
Dissection of the early steps in the porphobilinogen synthase catalyzed reaction. Requirements for Schiff's base formation.
Topics: Aminolevulinic Acid; Animals; Apoenzymes; Borohydrides; Cattle; Liver; Macromolecular Substances; Methyl Methanesulfonate; Porphobilinogen; Porphobilinogen Synthase; Schiff Bases; Zinc | 1986 |
Sorbent therapy of the porphyrias. V. Adsorption of the porphyrin precursors delta-aminolevulinic acid and porphobilinogen by sorbents in vitro.
Topics: Adsorption; Aminolevulinic Acid; Charcoal; Cholestyramine Resin; Kinetics; Levulinic Acids; Porphobilinogen | 1986 |
[Acute porphyria: 2 clinical cases].
Topics: Acute Disease; Adult; Aminolevulinic Acid; Female; Humans; Liver; Porphobilinogen; Porphyrias; Porphyrins; Uroporphyrins | 1985 |
Influence of chloroquine on the porphyrin metabolism.
Topics: 7-Alkoxycoumarin O-Dealkylase; Aminolevulinic Acid; Aminopyrine N-Demethylase; Animals; Aryl Hydrocarbon Hydroxylases; Chloroquine; Cytochrome P-450 Enzyme System; Disease Models, Animal; Female; Hexachlorobenzene; Microsomes, Liver; Oxygenases; Porphobilinogen; Porphyrias; Porphyrins; Rats; Rats, Inbred Strains | 1985 |
Use of transcutaneous nerve stimulation in the attacks of acute intermittent porphyria.
Topics: Acute Disease; Adult; Aminolevulinic Acid; Electric Stimulation Therapy; Female; Humans; Porphobilinogen; Porphyrias; Porphyrins; Transcutaneous Electric Nerve Stimulation | 1985 |
Hyperinsulinemia in acute intermittent porphyria.
Topics: Acute Disease; Adolescent; Adult; Aminolevulinic Acid; Female; Glucose Tolerance Test; Humans; Hyperinsulinism; Insulin; Liver Diseases; Porphobilinogen; Porphyrias | 1985 |
Porphyrins in Rotor's syndrome: a study on an Italian family.
Topics: Adult; Aminolevulinic Acid; Coproporphyrins; Female; Humans; Jaundice; Liver; Male; Porphobilinogen; Porphyrins; Syndrome | 1986 |
Detection of delta-aminolevulinic acid, porphobilinogen and porphyrins related to heme biosynthesis by high-performance liquid chromatography.
Topics: Aminolevulinic Acid; Chromatography, High Pressure Liquid; Heme; Hydrogen-Ion Concentration; Indicators and Reagents; Levulinic Acids; o-Phthalaldehyde; Porphobilinogen; Porphyrins | 1986 |
[Porphyrins and their precursors in the urine of patients with suspected porphyria; a 16-year experience].
Topics: Adult; Aminolevulinic Acid; Female; Humans; Levulinic Acids; Male; Middle Aged; Porphobilinogen; Porphyrias; Porphyrins | 1985 |
Mechanism of action of 5-aminolaevulinate dehydratase from human erythrocytes.
Topics: Aminolevulinic Acid; Erythrocytes; Humans; Models, Biological; Porphobilinogen; Porphobilinogen Synthase | 1985 |
Occupational lead exposure: studies in two brothers showing differential susceptibility to lead.
Topics: Adult; Aminolevulinic Acid; Environmental Exposure; Humans; Hydroxymethylbilane Synthase; Lead; Lead Poisoning; Male; Metals; Occupational Diseases; Pedigree; Porphobilinogen; Porphobilinogen Synthase | 1985 |
Stimulation of 5-aminolevulinic acid metabolism by uroporphyrinogen I in rat liver homogenate.
Topics: Aminolevulinic Acid; Animals; Cell-Free System; Heme; In Vitro Techniques; Levulinic Acids; Liver; Male; Porphobilinogen; Porphyrinogens; Porphyrins; Rats; Rats, Inbred Strains; Uroporphyrinogens | 1985 |
"Glucose effect" and rate limiting function of uroporphyrinogen synthase on porphyrin metabolism in hepatocyte culture: relationship with human acute hepatic porphyrias.
Topics: 5-Aminolevulinate Synthetase; Aminolevulinic Acid; Ammonia-Lyases; Animals; Cells, Cultured; Chick Embryo; Glucose; Heme; Humans; Hydroxymethylbilane Synthase; Kinetics; Liver; Liver Diseases; Meprobamate; Porphobilinogen; Porphyrias; Porphyrins | 1985 |
[Experimental porphyria model with hexachlorocyclohexane].
Topics: Aminolevulinic Acid; Animals; Chlorobenzenes; Diet; Disease Models, Animal; Feces; Female; Hexachlorocyclohexane; Lethal Dose 50; Male; Porphobilinogen; Porphyrias; Porphyrins; Rats | 1974 |
[Ion-exchange chromatography in the diagnosis of hepatic porphyria].
Topics: Amines; Aminolevulinic Acid; Anion Exchange Resins; Chromatography, Ion Exchange; Humans; Ketones; Porphobilinogen; Porphyrias, Hepatic | 1974 |
The reversal of experimental porphyria and the prevention of induction of hepatic mixed-function oxidase by acetate.
Topics: 5-Aminolevulinate Synthetase; Acetates; Aminolevulinic Acid; Animals; Cytochrome c Group; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Dicarboxylic Acids; Enzyme Induction; Liver; Male; Microsomes, Liver; Mixed Function Oxygenases; Oxidoreductases; Phenobarbital; Porphobilinogen; Porphyrias; Porphyrins; Pyridines; Rats; Spectrophotometry; Sulfanilamides | 1974 |
New method for determination of aminolaevulinate dehydratase activity of human erythrocytes as an index of lead exposure.
Topics: Aminolevulinic Acid; Buffers; Colorimetry; Erythrocytes; Humans; Hydro-Lyases; Hydrogen-Ion Concentration; Indicators and Reagents; Lead Poisoning; Mathematics; Methods; Phosphates; Porphobilinogen; Porphobilinogen Synthase; Pyrroles; Trichloroacetic Acid | 1974 |
[Genetic prognosis of a mother with acute intermittent porphyria (hepatic form)].
Topics: Acute Disease; Adolescent; Adult; Aminolevulinic Acid; Female; Genes, Dominant; Genetic Counseling; Humans; Liver Diseases; Male; Porphobilinogen; Porphyrias | 1974 |
A red cell enzyme method for the diagnosis of acute intermittent porphyria.
Topics: Acute Disease; Aminolevulinic Acid; Ammonia-Lyases; Erythrocytes; Freezing; Hemolysis; Hot Temperature; Humans; Methods; Porphobilinogen; Porphyrias; Porphyrins | 1974 |
Effect of vitamin E on delta-aminolevulinic acid dehydratase activity in weanling rabbits with chronic plumbism.
Topics: 5-Aminolevulinate Synthetase; Aminolevulinic Acid; Animals; Chronic Disease; Dose-Response Relationship, Drug; Erythrocytes; Hematocrit; Hydro-Lyases; Lead; Lead Poisoning; Liver; Male; Organ Size; Porphobilinogen; Porphobilinogen Synthase; Rabbits; Vitamin E | 1974 |
Delta-aminolevulinic acid uptake by rabbit brain cerebral cortex.
Topics: Allosteric Regulation; Amino Acids; Aminolevulinic Acid; Animals; Biological Transport, Active; Calcium; Carbon Radioisotopes; Cerebral Cortex; Cyanides; Dinitrophenols; In Vitro Techniques; Inulin; Ketoglutaric Acids; Kinetics; Levulinic Acids; Male; Osmolar Concentration; Ouabain; Phenobarbital; Porphobilinogen; Potassium; Rabbits; Sodium; Temperature; Time Factors | 1974 |
Lead poisoning with low blood lead levels.
Topics: Adult; Aminolevulinic Acid; Hemoglobins; Humans; Lead; Lead Poisoning; Male; Occupational Diseases; Porphobilinogen; Porphyrias | 1974 |
Comparative aspects of porphyria in man and animals.
Topics: Adult; Aminolevulinic Acid; Animals; Cattle; Drug Stability; Female; Genes, Recessive; Heme; Heterozygote; Hot Temperature; Humans; Isomerases; Kinetics; Male; Pedigree; Porphobilinogen; Porphyrias; Porphyrins; Reticulocytes; Sciuridae | 1974 |
A rapid method for the differentiation of Haemophilus strains. The porphyrin test;.
Topics: Aminolevulinic Acid; Culture Media; Haemophilus; Hemin; Methods; Porphobilinogen; Porphyrins | 1974 |
[Comments on paper "Zwei Suchteste für Porphyrein". (Doss, M. and Schmidt, A., (1972) this j. 10 (230-231)].
Topics: Acetates; Aminolevulinic Acid; Chloroform; Coloring Agents; Humans; Indicators and Reagents; Methods; Porphobilinogen; Porphyrias; Resins, Plant; Solvents; Urobilinogen | 1973 |
[Mechanism of delta-aminolevulinic acid neurotoxicity].
Topics: Aminolevulinic Acid; Animals; Binding Sites; Cells, Cultured; Chick Embryo; Corpus Striatum; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Kainic Acid; Levulinic Acids; Nerve Tissue; Neurons; Porphobilinogen | 1981 |
Effects of delta-aminolaevulinic acid, porphobilinogen and structurally related amino acids on 2-deoxy-glucose uptake in cultured neurons.
Topics: Aminolevulinic Acid; Animals; Brain; Chick Embryo; Deoxy Sugars; Deoxyglucose; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Kainic Acid; Kinetics; Levulinic Acids; Muscimol; Neurons; Porphobilinogen | 1982 |
Studies on porphyrin biosynthesis in erythrocytes after incubation with delta-aminolaevulinic acid in patients with acute leukemia.
Topics: Adult; Aminolevulinic Acid; Anemia; Erythrocytes; Female; Humans; Leukemia; Levulinic Acids; Male; Middle Aged; Porphobilinogen; Porphyrins; Protoporphyrins | 1981 |
Serine and glycine-induced catalepsy in porphyric rats: an animal model for psychosis?
Topics: Allylisopropylacetamide; Aminolevulinic Acid; Animals; Catalepsy; Disease Models, Animal; Glycine; Humans; Male; Phenobarbital; Porphobilinogen; Porphyrias; Psychotic Disorders; Rats; Rats, Inbred Strains; Serine | 1983 |
Charcoal haemoperfusion and haemodialysis in acute intermittent porphyria.
Topics: Acute Disease; Adult; Aminolevulinic Acid; Charcoal; Female; Hemoperfusion; Humans; Porphobilinogen; Porphyrias; Renal Dialysis | 1983 |
Excretion of porphyrins and porphyrin precursors during neuromuscular paralysis produced by dithiobiuret.
Topics: Aminolevulinic Acid; Animals; Disease Models, Animal; Levulinic Acids; Male; Muscle Hypotonia; Neuromuscular Diseases; Paralysis; Porphobilinogen; Porphyrias; Porphyrins; Rats; Thiourea; Time Factors | 1984 |
Sorbent therapy of the porphyrias. III. Comparative efficacy of experimental plasma perfusion with several commercial hemoperfusion cartridges.
Topics: Aminolevulinic Acid; Charcoal; Hemoperfusion; Humans; Porphobilinogen; Porphyrias | 1984 |
[Urinary and fecal excretion of porphyrins and their precursors in leukemia patients].
Topics: Acute Disease; Adolescent; Adult; Aged; Aminolevulinic Acid; Coproporphyrins; Feces; Female; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Levulinic Acids; Male; Middle Aged; Porphobilinogen; Porphyrins; Protoporphyrins; Uroporphyrins | 1983 |
Analysis of porphyrin precursors, 5-aminolevulinic acid derivatives by isotachophoresis.
Topics: Aminolevulinic Acid; Chlorella; Colorimetry; Electrophoresis; Levulinic Acids; Porphobilinogen; Porphyrins; Transaminases; Valerates | 1983 |
A quantitative assay of porphobilinogen (PBG) and delta-aminolevulinic acid (ALA) in the urine of one hundred normal Punjabis. A spectrophotometric study.
Topics: Adolescent; Adult; Age Factors; Aged; Aminolevulinic Acid; Analysis of Variance; Body Weight; Child; Child, Preschool; Diet, Vegetarian; Female; Hemoglobins; Humans; Levulinic Acids; Male; Middle Aged; Porphobilinogen | 1983 |
[A case of acute hepatic porphyria].
Topics: Acute Disease; Adult; Aminolevulinic Acid; Coproporphyrins; Humans; Liver Diseases; Male; Porphobilinogen; Porphyrias | 1983 |
[Clinical heterogeneity of hereditary coproporphyria: diagnostic usefulness of biochemical studies. Study of a familial case].
Topics: Aminolevulinic Acid; Coproporphyrins; Female; Humans; Middle Aged; Pedigree; Porphobilinogen; Porphyrias; Porphyrins; Protoporphyrins | 1983 |
[Hereditary coproporphyria in 2 Dutch families].
Topics: Adult; Aged; Aminolevulinic Acid; Coproporphyrins; Feces; Female; Humans; Male; Middle Aged; Pedigree; Porphobilinogen; Porphyrias; Porphyrins | 1984 |
Seizure management in acute hepatic porphyria: risks of valproate and clonazepam.
Topics: 5-Aminolevulinate Synthetase; Adult; Aminolevulinic Acid; Animals; Benzodiazepinones; Chick Embryo; Clonazepam; Cytochrome P-450 Enzyme System; Hemin; Humans; Liver Diseases; Male; Porphobilinogen; Porphyrias; Rats; Seizures; Valproic Acid | 1980 |
[Studies on patients with polychlorinated biphenyls poisoning. Determination of urinary coproporphyrin, uroporphyrin, delta-aminolevulinic acid, and porphobilinogen (author's transl)].
Topics: Adolescent; Adult; Aminolevulinic Acid; Child; Coproporphyrins; Female; Humans; Levulinic Acids; Male; Polychlorinated Biphenyls; Porphobilinogen; Porphyrins; Uroporphyrins | 1980 |
Studies on patients with polychlorinated biphenyl poisoning. 2. Determination of urinary coproporphyrin, uroporphyrin, delta-aminolevulinic acid and porphobilinogen.
Topics: Aminolevulinic Acid; Coproporphyrins; Heme; Humans; Polychlorinated Biphenyls; Porphobilinogen; Uroporphyrins | 1980 |
Protoporphyrin formation in Rhizobium japonicum.
Topics: Aerobiosis; Aminolevulinic Acid; Anaerobiosis; Coproporphyrinogen Oxidase; Coproporphyrinogens; Coproporphyrins; Porphobilinogen; Porphyrins; Protoporphyrins; Rhizobium; Uroporphyrins | 1983 |
Failure of delta-aminolaevulinic acid and porphobilinogen to alter renal salt and water excretion in the dog.
Topics: Aminolevulinic Acid; Animals; Body Water; Dogs; Female; Kidney; Levulinic Acids; Male; Porphobilinogen; Sodium; Vasopressins | 1983 |
Pathogenesis and treatment of acute intermittent porphyria: discussion paper.
Topics: Acute Disease; Aminolevulinic Acid; Blood-Brain Barrier; Heme; Humans; Liver Diseases; Porphobilinogen; Porphyrias | 1983 |
Sorbent therapy of the porphyrias. II. Experimental plasma or hemoperfusion with a commercial charcoal cartridge.
Topics: Adsorption; Aminolevulinic Acid; Charcoal; Evaluation Studies as Topic; Hemin; Hemoperfusion; Humans; Porphobilinogen; Porphyrias; Sodium Salicylate | 1983 |
Acute intermittent porphyria.
Topics: Acute Disease; Adult; Aminolevulinic Acid; Female; Humans; Male; Porphobilinogen; Porphyrias; Seizures; Syndrome; Vomiting | 1981 |
An acute attack of variegate porphyria complicated by severe autonomic neuropathy.
Topics: Acute Disease; Adult; Aminolevulinic Acid; Autonomic Nervous System Diseases; Female; Humans; Porphobilinogen; Porphyrias; Porphyrins; Skin Diseases | 1981 |
[Influence of p-amino-benzoic acid on the hexachlorobenzene induced porphyria in the rat (author's transl)].
Topics: 4-Aminobenzoic Acid; Aminobenzoates; Aminolevulinic Acid; Animals; Chlorobenzenes; Cytochrome P-450 Enzyme System; Drug Interactions; Female; Glycine; Hexachlorobenzene; Porphobilinogen; Porphyrias; Porphyrins; Rats | 1980 |
Alterations in haem biosynthesis during the human menstrual cycle: studies in normal subjects and patients with latent and active acute intermittent porphyria.
Topics: 5-Aminolevulinate Synthetase; Adrenal Cortex Hormones; Adult; Aminolevulinic Acid; Erythrocytes; Female; Heme; Humans; Hydroxymethylbilane Synthase; Leukocytes; Liver Diseases; Male; Menstruation; Middle Aged; Porphobilinogen; Porphyrias | 1982 |
Acute intermittent porphyria.
Topics: Acute Disease; Aminolevulinic Acid; Humans; Levulinic Acids; Liver Diseases; Porphobilinogen; Porphyrias | 1982 |
[Porphyrin metabolic indices in the diagnosis of anemia in thalassemia].
Topics: Adolescent; Adult; Aminolevulinic Acid; Anemia; Child; Coproporphyrins; Erythrocytes; Female; Free Radicals; Humans; Male; Porphobilinogen; Porphyrins; Thalassemia; Uroporphyrins | 1982 |
Intermittent acute porphyria.
Topics: Acute Disease; Adult; Aminolevulinic Acid; Female; Humans; Porphobilinogen; Porphyrias; Porphyrins | 1982 |
[Hemin treatment in a case of porphyria variegata].
Topics: Adult; Aminolevulinic Acid; Coproporphyrins; Female; Heme; Hemin; Humans; Liver Diseases; Porphobilinogen; Porphyrias; Uroporphyrins | 1982 |
Uroporphyrinogen-I-synthetase activity in red blood cells of lead-exposed workers.
Topics: Aminolevulinic Acid; Ammonia-Lyases; Dithiothreitol; Environmental Exposure; Enzyme Activation; Erythrocytes; Humans; Hydroxymethylbilane Synthase; Lead; Porphobilinogen; Porphobilinogen Synthase; Zinc | 1982 |
Determination of 5-aminolaevulinic acid dehydrase activity in erythrocytes by high-performance liquid chromatography.
Topics: Alcoholism; Aminolevulinic Acid; Chromatography, High Pressure Liquid; Erythrocytes; Humans; Porphobilinogen; Porphobilinogen Synthase | 1981 |
[Variegate porphyria; a family study].
Topics: Adult; Aminolevulinic Acid; Female; Humans; Male; Middle Aged; Pedigree; Porphobilinogen; Porphyrias; Porphyrins; Vitiligo | 1981 |
Normal erythrocyte uroporphyrinogen I synthase in a kindred with acute intermittent porphyria.
Topics: Aminolevulinic Acid; Ammonia-Lyases; Erythrocytes; Feces; Finland; Humans; Hydroxymethylbilane Synthase; Pedigree; Porphobilinogen; Porphyrias | 1981 |
Acute intermittent porphyria. A case report.
Topics: Acute Disease; Adult; Aminolevulinic Acid; Coproporphyrins; Feces; Female; Humans; Male; Porphobilinogen; Porphyrias; Uroporphyrins | 1981 |
Conversion of 5-aminolaevulinate into haem by liver homogenates. Comparison of rat and chick embryo.
Topics: Aminolevulinic Acid; Animals; Chick Embryo; Ferrous Compounds; Heme; In Vitro Techniques; Kinetics; Levulinic Acids; Liver; Male; Porphobilinogen; Porphyrins; Protoporphyrins; Rats; Rats, Inbred Strains | 1981 |
[Porphyria variegata in Poland. Diagnosis and differentiation].
Topics: Adolescent; Adult; Aminolevulinic Acid; Child; Diagnosis, Differential; Feces; Female; Humans; Male; Middle Aged; Poland; Porphobilinogen; Porphyrias; Porphyrins | 1980 |
Effect of chlorophenols on porphyrin metabolism in rats and chick embryo.
Topics: 5-Aminolevulinate Synthetase; Aminolevulinic Acid; Animals; Chick Embryo; Chlorophenols; Female; Intestinal Mucosa; Intestines; Kidney; Liver; Pentachlorophenol; Porphobilinogen; Porphyrins; Rats; Species Specificity; Spleen | 1980 |
A clinical porphyrin unit: four years' experience.
Topics: Aminolevulinic Acid; Australia; Hospital Units; Humans; Porphobilinogen; Porphyrias; Porphyrins; Reference Values | 1980 |
Afro-Americans and acute intermittent porphyria (AIP).
Topics: Acute Disease; Adolescent; Adult; Africa; Aminolevulinic Acid; Black People; Child; Child, Preschool; Female; Humans; Male; Middle Aged; Porphobilinogen; Porphyrias; Porphyrins; United States | 1980 |
Acute intermittent porphyria--another approach to therapy.
Topics: 5-Aminolevulinate Synthetase; Acute Disease; Adult; Aminolevulinic Acid; Ammonia-Lyases; Female; Folic Acid; Humans; Male; Porphobilinogen; Porphobilinogen Synthase; Porphyrias; Porphyrins | 1980 |
Acute hepatic porphyria syndrome with porphobilinogen synthase defect.
Topics: Acute Disease; Adult; Amino Acids; Aminolevulinic Acid; Erythrocytes; Feces; Female; Humans; Lead; Liver Diseases; Male; Porphobilinogen; Porphobilinogen Synthase; Porphyrias; Porphyrins; Syndrome | 1980 |
Effect of cadmium on porphyrin biosynthesis-I.
Topics: Aminolevulinic Acid; Ammonia-Lyases; Animals; Cadmium; Cadmium Poisoning; Erythrocytes; Feces; Female; Kidney; Kinetics; Liver; Porphobilinogen; Porphobilinogen Synthase; Porphyrins; Rats | 1980 |
Anticonvulsant-induced unclassified porphyria.
Topics: Adult; Aminolevulinic Acid; Anticonvulsants; Diagnosis, Differential; Epilepsy; Humans; Male; Phenobarbital; Phenytoin; Porphobilinogen; Porphyrias; Porphyrins | 1980 |
[Features of porphobilinogen synthesis from delta-aminolevulinic acid in the tissues of the internal organs of rats].
Topics: Aminolevulinic Acid; Animals; Body Weight; Kidney; Lead Poisoning; Levulinic Acids; Liver; Male; Organ Size; Porphobilinogen; Porphobilinogen Synthase; Rats; Spleen | 1980 |
Testing the porphyrinogenicity of propofol in a primed rat model.
Topics: 5-Aminolevulinate Synthetase; Allylisopropylacetamide; Aminolevulinic Acid; Anesthetics, Intravenous; Animals; Cytochrome P-450 Enzyme System; Liver; Male; Porphobilinogen; Porphyrias, Hepatic; Porphyrins; Propofol; Random Allocation; Rats; Rats, Sprague-Dawley | 1995 |
Dual porphyria of coexisting variegata and cutanea tarda.
Topics: Adult; Aged; Aminolevulinic Acid; Feces; Female; Humans; Male; Porphobilinogen; Porphyria Cutanea Tarda; Porphyrias, Hepatic; Porphyrins; Reference Values | 1995 |
Absence of circadian variations in urinary porphyrin excretion in normal subjects.
Topics: Adult; Aminolevulinic Acid; Circadian Rhythm; Female; Humans; Hydrogen-Ion Concentration; Male; Porphobilinogen; Porphyrins | 1995 |
Hormonal oral contraceptives, urinary porphyrin excretion and porphyrias.
Topics: Adult; Aminolevulinic Acid; Contraceptives, Oral, Combined; Contraceptives, Oral, Hormonal; Coproporphyrins; Desogestrel; Ethinyl Estradiol; Female; Humans; Norpregnenes; Porphobilinogen; Porphyrias; Porphyrias, Hepatic; Porphyrins; Uroporphyrins | 1995 |
Clinical usefulness of cimetidine treatment for acute relapse in intermittent porphyria.
Topics: Acute Disease; Adult; Aminolevulinic Acid; Blood Glucose; Cimetidine; Coproporphyrins; Feces; Humans; Male; Porphobilinogen; Porphyrias; Recurrence; Uroporphyrins | 1995 |
Elevated porphyrins following propofol anaesthesia in acute intermittent porphyria.
Topics: Adult; Aminolevulinic Acid; Anesthesia, General; Humans; Male; Porphobilinogen; Porphyria, Acute Intermittent; Porphyrins; Propofol | 1994 |
Safety of general anaesthesia and surgery in acute hepatic porphyria.
Topics: Acute Disease; Adult; Aged; Aminolevulinic Acid; Anesthesia, General; Child, Preschool; Contraindications; Female; Humans; Male; Middle Aged; Porphobilinogen; Porphyrias, Hepatic; Postoperative Complications; Prospective Studies; Retrospective Studies; Risk Factors; Surgical Procedures, Operative | 1994 |
[Clinical and laboratory findings concerning at first dietary and afterwards cimetidine treatment of acute intermittent porphyria].
Topics: Acute Disease; Adult; Aminolevulinic Acid; Cimetidine; Coproporphyrins; Female; Humans; Middle Aged; Porphobilinogen; Porphyrias; Porphyrins; Spectrophotometry; Time Factors; Uroporphyrins | 1994 |
Porphyrinogenic effects of atracurium, vecuronium, and pancuronium in a primed rat model.
Topics: 5-Aminolevulinate Synthetase; Aminolevulinic Acid; Animals; Atracurium; Liver; Male; Pancuronium; Porphobilinogen; Porphyrias; Porphyrins; Rats; Rats, Sprague-Dawley; Vecuronium Bromide | 1994 |
Coexistence of hereditary coproporphyria with acute intermittent porphyria.
Topics: Adolescent; Adult; Aged; Aminolevulinic Acid; Child; Female; Humans; Male; Middle Aged; Pedigree; Porphobilinogen; Porphyria, Acute Intermittent; Porphyrias, Hepatic | 1994 |
Haem precursor effects on [3H]-PK 11195 binding to platelets.
Topics: Aminolevulinic Acid; Blood Platelets; Female; Humans; In Vitro Techniques; Isoquinolines; Ligands; Male; Porphobilinogen; Protoporphyrins; Receptors, GABA-A | 1994 |
[Porphyria and porphyrinuria].
Topics: Aminolevulinic Acid; Diagnosis, Differential; Humans; Porphobilinogen; Porphyrias; Porphyrins; Retrospective Studies | 1993 |
delta-Aminolevulinic acid effects on neuronal and glial tumor cell lines.
Topics: Aminolevulinic Acid; Cell Survival; Deferoxamine; Glioblastoma; Hemin; Humans; Nervous System Diseases; Neuroblastoma; Porphobilinogen; Porphyria, Acute Intermittent; Tumor Cells, Cultured | 1993 |
Childhood porphyrias: implications and treatments.
Topics: Adolescent; Aged; Aminolevulinic Acid; Child; Child, Preschool; Coproporphyrinogen Oxidase; Female; Flavoproteins; Humans; Hydroxymethylbilane Synthase; Male; Mitochondrial Proteins; Oxidoreductases; Oxidoreductases Acting on CH-CH Group Donors; Porphobilinogen; Porphyrias; Protoporphyrinogen Oxidase; Reference Values; Uroporphyrinogen Decarboxylase | 1993 |
Altered 5-aminolevulinic acid metabolism leading to pseudoporphyria in hemodialysed patients.
Topics: Acute Disease; Adult; Aged; Aminolevulinic Acid; Case-Control Studies; Female; Hot Temperature; Humans; Hydroxymethylbilane Synthase; Male; Middle Aged; Porphobilinogen; Porphobilinogen Synthase; Porphyrias; Renal Dialysis; Zinc | 1996 |
[Urinary porphyrin excretion in human immunodeficiency virus infection].
Topics: Acquired Immunodeficiency Syndrome; Adult; Aged; Aminolevulinic Acid; Coproporphyrins; Female; HIV Infections; Humans; Male; Middle Aged; Porphobilinogen; Porphyrins; Prospective Studies; Time Factors; Uroporphyrins | 1996 |
Determination of 5-aminolaevulinic acid dehydratase activity in erythrocytes and porphobilinogen in urine by micellar electrokinetic capillary chromatography.
Topics: Aminolevulinic Acid; Electrophoresis, Capillary; Erythrocytes; Humans; Hydrogen-Ion Concentration; Lead Poisoning; Micelles; Porphobilinogen; Porphobilinogen Synthase; Porphyria, Acute Intermittent; Spectrophotometry, Ultraviolet | 1996 |
Effect of chronic anesthesia on the drug-metabolizing enzyme system and heme pathway regulation.
Topics: 5-Aminolevulinate Synthetase; Aminolevulinic Acid; Anesthetics, Inhalation; Animals; Cytochrome P-450 Enzyme System; Enflurane; Heme; Hypnotics and Sedatives; Isoflurane; Liver; Male; Mice; Phenobarbital; Porphobilinogen; Porphyrins | 1997 |
Molecular analysis of porphobilinogen (PBG) deaminase gene mutations in acute intermittent porphyria: first study in patients of Slavic origin.
Topics: Aminolevulinic Acid; Czech Republic; Exons; Genetic Testing; Humans; Hydroxymethylbilane Synthase; Introns; Mutation; Porphobilinogen; Porphyria, Acute Intermittent; Slovakia | 1997 |
Effects of clonidine in a primed rat model of acute hepatic porphyria.
Topics: 5-Aminolevulinate Synthetase; Allylisopropylacetamide; Aminolevulinic Acid; Aminopyrine N-Demethylase; Animals; Antihypertensive Agents; Clonidine; Cytochrome P-450 CYP1A1; Dicarbethoxydihydrocollidine; Enzyme Induction; Female; Isoenzymes; Porphobilinogen; Porphyria, Acute Intermittent; Rats | 1997 |
5-Aminolaevulinic acid-induced protoporphyrin IX accumulation in tissues: pharmacokinetics after oral or intravenous administration.
Topics: Administration, Oral; Alanine Transaminase; Aminolevulinic Acid; Animals; Aspartate Aminotransferases; Creatinine; Injections, Intravenous; Kidney Function Tests; Male; Microscopy, Confocal; Photosensitizing Agents; Porphobilinogen; Protoporphyrins; Rats; Rats, Inbred Strains; Tissue Distribution; Urea | 1998 |
Prolonged loss of consciousness and elevated porphyrins following propofol administrations.
Topics: Adult; Aminolevulinic Acid; Anesthetics, Intravenous; Coproporphyrins; Humans; Male; Porphobilinogen; Porphyrins; Propofol; Unconsciousness | 1998 |
The diagnosis of porphyria.
Topics: Aminolevulinic Acid; Female; Genetic Techniques; Genetic Testing; Heme; Humans; Mutation; Porphobilinogen; Porphyrias; Porphyrins | 1999 |
A splicing mutation in the hydroxymethylbilane synthase gene in a Japanese family with acute intermittent porphyria.
Topics: Adult; Aminolevulinic Acid; Child, Preschool; Deoxyribonucleases, Type II Site-Specific; Erythrocytes; Female; Humans; Hydroxymethylbilane Synthase; Japan; Male; Mutation; Pedigree; Point Mutation; Polymorphism, Single-Stranded Conformational; Porphobilinogen; Porphyria, Acute Intermittent; RNA Splicing | 1999 |
Capillary zone electrophoresis/mass spectrometry of 5-aminolaevulinic acid and porphobilinogen.
Topics: Aminolevulinic Acid; Electrophoresis, Capillary; Mass Spectrometry; Porphobilinogen; Sensitivity and Specificity | 2000 |
Inhibition of Escherichia coli porphobilinogen synthase using analogs of postulated intermediates.
Topics: Aminolevulinic Acid; Binding, Competitive; Catalytic Domain; Dicarboxylic Acids; Enzyme Inhibitors; Escherichia coli; Kinetics; Models, Chemical; Porphobilinogen; Porphobilinogen Synthase; Structure-Activity Relationship; Substrate Specificity | 2000 |
Porphyrin biosynthesis intermediates are not regulating delta-aminolevulinic acid transport in Saccharomyces cerevisiae.
Topics: 5-Aminolevulinate Synthetase; Aminolevulinic Acid; Biological Transport; Ferrochelatase; GABA Plasma Membrane Transport Proteins; Genes, Fungal; Kinetics; Membrane Transport Proteins; Mutation; Organic Anion Transporters; Porphobilinogen; Porphobilinogen Synthase; Porphyrins; Protoporphyria, Erythropoietic; Protoporphyrins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Uroporphyrinogen Decarboxylase; Uroporphyrins | 2000 |
Porphyrin biosynthesis in human Barrett's oesophagus and adenocarcinoma after ingestion of 5-aminolaevulinic acid.
Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Barrett Esophagus; Esophageal Neoplasms; Female; Ferrochelatase; Heme; Humans; Hydroxymethylbilane Synthase; Male; Middle Aged; Photochemotherapy; Photosensitizing Agents; Porphobilinogen; Porphyrins; Protoporphyrins | 2000 |
Hereditary coproporphyria in Germany: clinical-biochemical studies in 53 patients.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Arginine; Child; Chromatography, High Pressure Liquid; Coproporphyrinogen Oxidase; Coproporphyrins; Feces; Female; Germany; Heme; Heterozygote; Humans; Isomerism; Male; Middle Aged; Porphobilinogen; Porphyrias, Hepatic; Uroporphyrins | 2000 |
Suppression of the induction of long-term depression by carbon monoxide in rat cerebellar slices.
Topics: Aminolevulinic Acid; Animals; Carbon Monoxide; Cerebellum; Cyclic GMP; Excitatory Postsynaptic Potentials; Female; Long-Term Potentiation; Male; Neural Inhibition; Nitric Oxide; Organ Culture Techniques; Oxygen Consumption; Photosensitizing Agents; Porphobilinogen; Purkinje Cells; Rats; Rats, Wistar; Signal Transduction; Synaptic Transmission | 2001 |
Simultaneous determination of delta-aminolevulinic acid, porphobilinogen, levulinic acid and glycine in culture broth by capillary electrophoresis.
Topics: Aminolevulinic Acid; Calibration; Culture Media; Electrophoresis, Capillary; Glycine; Levulinic Acids; Porphobilinogen; Rhodobacter sphaeroides | 2001 |
Inhibition studies of porphobilinogen synthase from Escherichia coli differentiating between the two recognition sites.
Topics: Aminolevulinic Acid; Binding Sites; Enzyme Inhibitors; Escherichia coli; Kinetics; Porphobilinogen; Porphobilinogen Synthase; Substrate Specificity | 2001 |
Oxygen-mediated regulation of porphobilinogen formation in Rhodobacter capsulatus.
Topics: Aminolevulinic Acid; Bacterial Proteins; Bacteriochlorophylls; Escherichia coli Proteins; Genes, Bacterial; Hemin; Hydroxymethylbilane Synthase; Mixed Function Oxygenases; Molecular Sequence Data; Mutation; Oxygen; Porphobilinogen; Porphobilinogen Synthase; Protoporphyrins; Rhodobacter capsulatus; Transcription, Genetic | 2002 |
Molecular and biochemical studies of acute intermittent porphyria in 196 patients and their families.
Topics: Adolescent; Adult; Aged; Aminolevulinic Acid; DNA; Family; Feces; Female; Humans; Hydroxymethylbilane Synthase; Male; Middle Aged; Mutation; Porphobilinogen; Porphyria, Acute Intermittent; Porphyrins; Retrospective Studies; Sensitivity and Specificity; Sequence Analysis, DNA | 2002 |
5-Aminolevulinic acid synthesis in epimastigotes of Trypanosoma cruzi.
Topics: 5-Aminolevulinate Synthetase; Aminolevulinic Acid; Ammonia-Lyases; Animals; Heme; Porphobilinogen; Rhodobacter sphaeroides; Succinate-CoA Ligases; Transaminases; Trypanosoma cruzi | 2003 |
Acute intermittent porphyria in childhood: a population-based study.
Topics: Adolescent; Age Factors; Aminolevulinic Acid; Child; Child, Preschool; Female; Humans; Male; Photosensitizing Agents; Porphobilinogen; Porphyria, Acute Intermittent; Prospective Studies; Reference Values; Sweden | 2003 |
Measurement of urinary porphyrins and porphyrin precursors in Dutch hospital laboratories: a review of quality control over 5 years.
Topics: Aminolevulinic Acid; Clinical Chemistry Tests; Coproporphyrins; Humans; Laboratories, Hospital; Netherlands; Porphobilinogen; Porphyrins; Quality Control; Reproducibility of Results; Sensitivity and Specificity; Uroporphyrins | 2003 |
Stereochemistry and mechanism of the conversion of 5-aminolaevulinic acid into porphobilinogen catalysed by porphobilinogen synthase.
Topics: Aminolevulinic Acid; Animals; Bacillus subtilis; Binding Sites; Catalysis; Cattle; Deuterium; Kinetics; Models, Molecular; Porphobilinogen; Porphobilinogen Synthase; Stereoisomerism | 2003 |
Aminolaevulinic acid-induced protoporphyrin IX pharmacokinetics in central and peripheral arteries of the rat.
Topics: Aminolevulinic Acid; Animals; Arteries; Male; Mitochondria; Porphobilinogen; Protoporphyrins; Rats; Rats, Wistar; Time Factors | 2003 |
Conversion of alpha-aminolaevulinic acid to porphobilinogen in a tissue system.
Topics: Aminolevulinic Acid; Keto Acids; Ketones; Porphobilinogen; Porphyrins | 1953 |
The occurrence and determination of delta-amino-levulinic acid and porphobilinogen in urine.
Topics: Aminolevulinic Acid; Humans; Keto Acids; Ketones; Pigments, Biological; Porphobilinogen; Urine | 1956 |
Excretion of porphobilinogen and Delta-aminolaevulinic acid in acute porphyria.
Topics: Amino Acids; Aminolevulinic Acid; Biological Products; Humans; Pigments, Biological; Porphobilinogen; Porphyria, Acute Intermittent; Porphyrias | 1961 |
Delta-amino-levulinic acid, porphobilinogen, and porphyrin excretion throughout pregnancy in a patient with acute intermittent porphyria with "passive porphyria" in the infant.
Topics: Amino Acids; Aminolevulinic Acid; Female; Humans; Infant, Newborn, Diseases; Porphobilinogen; Porphyria, Acute Intermittent; Porphyrias; Porphyrins; Pregnancy; Pregnancy Complications | 1961 |
[Determination of 6-aminolevulinic acid and porphobilinogen in the urine].
Topics: Amino Acids; Aminolevulinic Acid; Bile Pigments; Humans; Levulinic Acids; Porphobilinogen; Porphyrins | 1962 |
[The influence of ionizing radiation on incorporation of 5-aminolevulinic acid and porphobilinogen into heme in vitro].
Topics: Amino Acids; Aminolevulinic Acid; Heme; In Vitro Techniques; Levulinic Acids; Porphobilinogen; Porphyrins; Proteins; Radiation Effects; Radiation, Ionizing | 1962 |
Urinary delta aminolaevulinic acid and porphobilinogen in lead-exposed workers.
Topics: Aminolevulinic Acid; Humans; Lead Poisoning; Levulinic Acids; Occupational Diseases; Pigments, Biological; Porphobilinogen | 1963 |
THE CHROMATOGRAPHIC SEPARATION, DETERMINATION, AND DAILY EXCRETION OF URINARY PORPHOBILINOGEN, AMINO ACETONE, AND DELTA-AMINOLEVULINIC ACID.
Topics: Acetone; Aminolevulinic Acid; Anemia; Anemia, Sickle Cell; Chromatography; Fluids and Secretions; Hodgkin Disease; Humans; Ion Exchange Resins; Ketones; Lead Poisoning; Leukemia; Levulinic Acids; Liver Cirrhosis; Multiple Myeloma; Neoplasms; Porphobilinogen; Porphyrias; Porphyrins; Urine | 1964 |
PORPHOBILINOGEN AND DELTA-AMINOLEVULINIC ACID EXCRETION IN MULTIPLE SCLEROSIS.
Topics: Amino Acids; Aminolevulinic Acid; Demyelinating Diseases; Diagnosis, Differential; Fluids and Secretions; Humans; Levulinic Acids; Multiple Sclerosis; Neoplasms; Poliomyelitis; Porphobilinogen; Porphyrias; Porphyrins; Pyrroles; Urine | 1965 |
Porphobilinogen and delta-amino levulinic acid in acute porphyria.
Topics: Aminolevulinic Acid; Humans; Keto Acids; Ketones; Porphobilinogen; Porphyria, Acute Intermittent; Porphyrias; Porphyrins | 1955 |
[Excretion of delta-aminolevulinic acid and porphobilinogen in experimental porphyria in rabbits].
Topics: Amino Acids; Aminolevulinic Acid; Animals; Humans; Porphobilinogen; Porphyrias; Rabbits | 1960 |
The metabolism of 5-aminolaevulinic acid, porphobilinogen, uroporphyrin and coproporphyrin in lead poisoning.
Topics: Amino Acids; Aminolevulinic Acid; Coproporphyrins; Lead Poisoning; Porphobilinogen; Porphyrins; Uroporphyrins | 1960 |
[On the excretion of 5-aminolevulinic acid and porphobilinogen in latent porphyria].
Topics: Amino Acids; Aminolevulinic Acid; Humans; Porphobilinogen; Porphyrias; Porphyrins; Pyrroles | 1961 |
Quantitative determination of porphobilinogen and delta-aminolevulinic acid in the urine.
Topics: Amino Acids; Aminolevulinic Acid; Humans; Porphobilinogen; Pyrroles | 1962 |
[5-Aminolevulinic acid and porphobilinogen in the urine of subjects with lead poisoning].
Topics: Amino Acids; Aminolevulinic Acid; Biological Products; Body Fluids; Humans; Lead Poisoning; Pigments, Biological; Porphobilinogen | 1961 |
Renal transplantation in a case of acute intermittent porphyria.
Topics: Aminolevulinic Acid; Azathioprine; Creatinine; Cyclosporine; Drug Interactions; Female; Graft Rejection; Humans; Immunosuppressive Agents; Kidney Failure, Chronic; Kidney Transplantation; Middle Aged; Mycophenolic Acid; Porphobilinogen; Porphyria, Acute Intermittent; Prednisolone; Renal Dialysis; Sweden; Treatment Outcome | 2003 |
The effects of inhibition of haem biosynthesis by griseofulvin on intestinal iron absorption.
Topics: Administration, Oral; Aminolevulinic Acid; Animals; Biological Transport; Body Weight; Cation Transport Proteins; Drug Interactions; Duodenum; Gene Expression; Griseofulvin; Heme; In Vitro Techniques; Intestinal Absorption; Iron-Binding Proteins; Iron, Dietary; Liver; Male; Mice; Organ Size; Porphobilinogen | 2004 |
The third case of Doss porphyria (delta-amino-levulinic acid dehydratase deficiency) in Germany.
Topics: Abdominal Pain; Adolescent; Aminolevulinic Acid; Dithiothreitol; Erythrocytes; Germany; Humans; Male; Mutation; Pedigree; Polyneuropathies; Porphobilinogen; Porphobilinogen Synthase; Porphyrins; Zinc | 2004 |
Developmental profiles of 5-aminolevulinate, porphobilinogen and porphobilinogen synthase activity in Pieris brassicae related to the synthesis of the bilin-binding protein.
Topics: Acetone; Aminolevulinic Acid; Animals; Butterflies; Carrier Proteins; Gene Expression Regulation, Developmental; Insect Proteins; Larva; Porphobilinogen; Porphobilinogen Synthase; Time Factors; Wings, Animal | 2005 |
Variations in porphobilinogen and 5-aminolevulinic acid concentrations in plasma and urine from asymptomatic carriers of the acute intermittent porphyria gene with increased porphyrin precursor excretion.
Topics: Adult; Aminolevulinic Acid; Chromatography, High Pressure Liquid; Female; Heterozygote; Humans; Male; Mass Spectrometry; Middle Aged; Porphobilinogen; Porphyria, Acute Intermittent | 2006 |
Estimation and application of biological variation of urinary delta-aminolevulinic acid and porphobilinogen in healthy individuals and in patients with acute intermittent porphyria.
Topics: Adult; Aminolevulinic Acid; Child; Female; Humans; Male; Middle Aged; Porphobilinogen; Porphyria, Acute Intermittent; Probability; Reference Values | 2006 |
Acute intermittent porphyria with peripheral neuropathy: a follow-up study after hematin treatment.
Topics: Adult; Aminolevulinic Acid; DNA Mutational Analysis; Female; Follow-Up Studies; Genetic Markers; Genetic Predisposition to Disease; Hemin; Humans; Hydroxymethylbilane Synthase; Motor Neuron Disease; Mutation; Pedigree; Peripheral Nervous System Diseases; Polyneuropathies; Porphobilinogen; Porphyria, Acute Intermittent; Treatment Outcome | 2007 |
Safe usage of isotretinoin in a woman with latent acute intermittent porphyria.
Topics: Acne Vulgaris; Adult; Aminolevulinic Acid; Dermatologic Agents; Female; Humans; Isotretinoin; Porphobilinogen; Porphyria, Acute Intermittent; Porphyrins | 2007 |
[Acute porphyrias: problem of primary diagnosis in Russia and CIS countries].
Topics: Adolescent; Adult; Aminolevulinic Acid; Diagnosis, Differential; Female; Humans; Hydroxymethylbilane Synthase; Male; Mass Screening; Middle Aged; Porphobilinogen; Porphyria, Acute Intermittent; Porphyrins; Retrospective Studies; Russia; Spectrophotometry | 2007 |
Intermittent unexplained abdominal pain: is it porphyria?
Topics: Abdominal Pain; Acute Disease; Adult; Aminolevulinic Acid; Anti-Infective Agents; Cimetidine; Contraceptives, Oral; Diet, Reducing; Enzyme Inhibitors; Female; Heme; Hemin; Humans; Liver; Liver Transplantation; Porphobilinogen; Porphyrias, Hepatic; Sulfamethoxazole; Trimethoprim; Urinary Tract Infections | 2007 |
Hemodialysis: a therapeutic option for severe attacks of acute intermittent porphyria in developing countries.
Topics: Adolescent; Aminolevulinic Acid; Developing Countries; Female; Humans; India; Porphobilinogen; Porphyria, Acute Intermittent; Renal Dialysis; Severity of Illness Index; Treatment Outcome; Urinary Incontinence | 2008 |
The effect of haem biosynthesis inhibitors and inducers on intestinal iron absorption and liver haem biosynthetic enzyme activities.
Topics: Allylisopropylacetamide; Aminolevulinic Acid; Animals; Antimicrobial Cationic Peptides; Duodenum; Enzyme Inhibitors; Heme; Hepcidins; Heptanoates; Intestinal Absorption; Iron Compounds; Male; Mice; Porphobilinogen; Porphobilinogen Synthase; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2008 |
A family with acute intermittent porphyria.
Topics: Adolescent; Aminolevulinic Acid; Family; Female; Genetic Predisposition to Disease; Humans; Pedigree; Porphobilinogen; Porphyria, Acute Intermittent; Urinalysis | 2008 |
Awareness is the name of the game: clinical and biochemical evaluation of a case of a girl diagnosed with acute intermittent porphyria associated with autism.
Topics: Adolescent; Aminolevulinic Acid; Autistic Disorder; Female; Humans; Hydroxymethylbilane Synthase; Mutation; Pedigree; Porphobilinogen; Porphyria, Acute Intermittent | 2009 |
Porphyrin precursors and porphyrins in three patients with acute intermittent porphyria and end-stage renal disease under different therapy regimes.
Topics: Adult; Aminolevulinic Acid; Female; Humans; Kidney Failure, Chronic; Middle Aged; Peritoneal Dialysis; Porphobilinogen; Porphyria, Acute Intermittent; Porphyrins; Renal Dialysis | 2009 |
Clinical, biochemical and genetic characteristics of Variegate Porphyria in Italy.
Topics: Adult; Aged; Aminolevulinic Acid; Female; Flavoproteins; Genetic Association Studies; Genotype; Humans; Italy; Male; Middle Aged; Mitochondrial Proteins; Polymorphism, Genetic; Porphobilinogen; Porphyria, Variegate; Porphyrins; Protoporphyrinogen Oxidase; White People | 2009 |
Porphobilinogen deaminase over-expression in hepatocytes, but not in erythrocytes, prevents accumulation of toxic porphyrin precursors in a mouse model of acute intermittent porphyria.
Topics: Aminolevulinic Acid; Animals; Bone Marrow Transplantation; Disease Models, Animal; Erythrocytes; Female; Gene Transfer Techniques; Hepatocytes; Humans; Hydroxymethylbilane Synthase; Mice; Mice, Inbred C57BL; Plasmids; Porphobilinogen; Porphyria, Acute Intermittent; Porphyrins | 2010 |
[Acute intermittent porphyria and inappropriate ADH syndrome].
Topics: Abdominal Pain; Adult; Aminolevulinic Acid; Coproporphyrins; Delayed Diagnosis; Dietary Carbohydrates; Feces; Female; Hemin; Humans; Hyponatremia; Inappropriate ADH Syndrome; Paresthesia; Porphobilinogen; Porphyria, Acute Intermittent; Quadriplegia; Sodium Chloride, Dietary; Vomiting | 2010 |
Acute porphyrias may be overlooked in patients taking methenamine hippurate.
Topics: Aged; Aminolevulinic Acid; Artifacts; Diagnostic Errors; Female; Hippurates; Humans; Methenamine; Porphobilinogen; Porphyria, Acute Intermittent; Uroporphyrins; Young Adult | 2010 |
Direct assay of delta-aminolevulinic acid dehydratase in heme biosynthesis for the detection of porphyrias by tandem mass spectrometry.
Topics: Aminolevulinic Acid; Deuterium; Erythrocytes; Heme; Humans; Kinetics; Porphobilinogen; Porphobilinogen Synthase; Porphyrias; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2010 |
Computational insights into the mechanism of porphobilinogen synthase.
Topics: Aminolevulinic Acid; Binding Sites; Biocatalysis; Catalytic Domain; Lysine; Porphobilinogen; Porphobilinogen Synthase; Protein Binding; Schiff Bases; Thermodynamics | 2010 |
[Porphyria. What to think in the absence of a cause of abdominal pain].
Topics: Abdominal Pain; Aminolevulinic Acid; Female; Humans; Porphobilinogen; Porphyria, Acute Intermittent; Young Adult | 2010 |
A LC-MS/MS method for the specific, sensitive, and simultaneous quantification of 5-aminolevulinic acid and porphobilinogen.
Topics: Adolescent; Adult; Aminolevulinic Acid; Animals; Child; Child, Preschool; Chromatography, Liquid; Disease Models, Animal; Female; Humans; Male; Middle Aged; Porphobilinogen; Porphyria, Acute Intermittent; Sensitivity and Specificity; Tandem Mass Spectrometry; Young Adult | 2011 |
Methods for analysis of photosynthetic pigments and steady-state levels of intermediates of tetrapyrrole biosynthesis.
Topics: Aminolevulinic Acid; Apoenzymes; Arabidopsis; Calibration; Carotenoids; Chemistry Techniques, Analytical; Chlorophyllides; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Heme; Horseradish Peroxidase; Photosynthesis; Pigments, Biological; Porphobilinogen; Protochlorophyllide; Spectrometry, Fluorescence; Tetrapyrroles | 2011 |
Neurological complications of acute intermittent porphyria.
Topics: Adolescent; Adult; Aminolevulinic Acid; Brain; Electroencephalography; Electromyography; Female; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Nervous System Diseases; Neural Conduction; Porphobilinogen; Porphyria, Acute Intermittent; Retrospective Studies; Tomography, X-Ray Computed; Young Adult | 2011 |
Travelling wave ion mobility mass spectrometry of 5-aminolaevulinic acid, porphobilinogen and porphyrins.
Topics: Aminolevulinic Acid; Porphobilinogen; Porphyrins; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2012 |
Direct and simultaneous determination of 5-aminolaevulinic acid and porphobilinogen in urine by hydrophilic interaction liquid chromatography-electrospray ionisation/tandem mass spectrometry.
Topics: Aminolevulinic Acid; Analysis of Variance; Chromatography, Liquid; Humans; Hydrophobic and Hydrophilic Interactions; Linear Models; Porphobilinogen; Porphyria, Acute Intermittent; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2012 |
Measurement of δ-aminolevulinate dehydratase activity.
Topics: Aminolevulinic Acid; Animals; Chromatography, High Pressure Liquid; Enzyme Assays; Enzyme Reactivators; Humans; Lead Poisoning; Porphobilinogen; Porphobilinogen Synthase; Spectrometry, Fluorescence; Spectrophotometry; Spectrophotometry, Ultraviolet; Uroporphyrins | 2001 |
Direct and simultaneous quantitation of 5-aminolaevulinic acid and porphobilinogen in human serum or plasma by hydrophilic interaction liquid chromatography-atmospheric pressure chemical ionization/tandem mass spectrometry.
Topics: Aminolevulinic Acid; Chromatography, Liquid; Humans; Hydrophobic and Hydrophilic Interactions; Least-Squares Analysis; Porphobilinogen; Porphyria, Acute Intermittent; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry | 2013 |
Hepatocyte transplantation ameliorates the metabolic abnormality in a mouse model of acute intermittent porphyria.
Topics: 5-Aminolevulinate Synthetase; Aminolevulinic Acid; Animals; Aryl Hydrocarbon Hydroxylases; Cells, Cultured; Cytochrome P450 Family 2; Disease Models, Animal; Hepatocytes; Hydroxymethylbilane Synthase; Male; Mice; Mice, Inbred C57BL; Porphobilinogen; Porphyria, Acute Intermittent; RNA, Messenger; Transplantation, Homologous | 2014 |
Urinary excretion of porphyrins, porphobilinogen and δ-aminolaevulinic acid following an attack of acute intermittent porphyria.
Topics: Aminolevulinic Acid; Female; Half-Life; Humans; Male; Porphobilinogen; Porphyria, Acute Intermittent; Porphyrins; Time | 2014 |
High prevalence of and potential mechanisms for chronic kidney disease in patients with acute intermittent porphyria.
Topics: Aged; Aminolevulinic Acid; Apoptosis; Cells, Cultured; Endoplasmic Reticulum Stress; Epithelial Cells; Epithelium; Female; Fibrosis; France; Glomerular Filtration Rate; Human Umbilical Vein Endothelial Cells; Humans; Hydroxymethylbilane Synthase; Hypertension; Kidney Tubules; Male; Middle Aged; Nephritis, Interstitial; Phenotype; Porphobilinogen; Porphyria, Acute Intermittent; Prevalence; Renal Insufficiency, Chronic; Tunica Intima | 2015 |
Liver Transplantation for Acute Intermittent Porphyria: Biochemical and Pathologic Studies of the Explanted Liver.
Topics: 5-Aminolevulinate Synthetase; Adult; Aminolevulinic Acid; Female; Heme; Humans; Hydroxymethylbilane Synthase; Liver; Liver Transplantation; Porphobilinogen; Porphyria, Acute Intermittent; RNA, Messenger; Uroporphyrins | 2015 |
The Porphobilinogen Conundrum in Prebiotic Routes to Tetrapyrrole Macrocycles.
Topics: Aminolevulinic Acid; Evolution, Chemical; Kinetics; Origin of Life; Porphobilinogen; Tetrapyrroles | 2017 |
Lifestyle factors including diet and biochemical biomarkers in acute intermittent porphyria: Results from a case-control study in northern Norway.
Topics: Acute Disease; Adult; Aged; Aminolevulinic Acid; Biomarkers; Case-Control Studies; Cross-Sectional Studies; Diet; Female; Humans; Insulin; Life Style; Male; Middle Aged; Norway; Porphobilinogen; Porphyria, Acute Intermittent; Resistin; Surveys and Questionnaires | 2019 |
Homozygous hydroxymethylbilane synthase knock-in mice provide pathogenic insights into the severe neurological impairments present in human homozygous dominant acute intermittent porphyria.
Topics: Aminolevulinic Acid; Animals; Central Nervous System; Gene Knock-In Techniques; Genes, Dominant; Homozygote; Humans; Hydroxymethylbilane Synthase; Liver; Mice; Mutation, Missense; Myelin Sheath; Nervous System Diseases; Phenobarbital; Porphobilinogen; Porphyria, Acute Intermittent; Psychomotor Disorders | 2019 |
Computational disease model of phenobarbital-induced acute attacks in an acute intermittent porphyria mouse model.
Topics: Aminolevulinic Acid; Animals; Computer Simulation; Disease Models, Animal; Male; Mice; Mice, Inbred C57BL; Phenobarbital; Porphobilinogen; Porphyria, Acute Intermittent; Porphyrins | 2019 |
Uncontrolled Acute Intermittent Porphyria as a Cause of Spontaneous Abortion.
Topics: Abortion, Spontaneous; Adult; Aminolevulinic Acid; Contraceptives, Oral, Hormonal; Disease Progression; Dydrogesterone; Female; Humans; Porphobilinogen; Porphyria, Acute Intermittent; Pregnancy; Progestins; Vacuum Curettage | 2020 |
Sars-Cov-2 interference in HEME production: is it the time for an early predictive biomarker?
Topics: Aminolevulinic Acid; Betacoronavirus; Biomarkers; Coronavirus Infections; COVID-19; Heme; Host-Pathogen Interactions; Humans; Interleukin-6; Pandemics; Pneumonia, Viral; Porphobilinogen; SARS-CoV-2; Thrombosis; Viral Proteins | 2020 |
Quantification of Urine and Plasma Porphyrin Precursors Using LC-MS in Acute Hepatic Porphyrias: Improvement in Routine Diagnosis and in the Monitoring of Kidney Failure Patients.
Topics: Aminolevulinic Acid; Chromatography, Liquid; Humans; Porphobilinogen; Porphyrias; Porphyrias, Hepatic; Porphyrins; Renal Insufficiency; Tandem Mass Spectrometry | 2023 |
Porphyrin precursors and risk of primary liver cancer in acute intermittent porphyria: A case-control study of 188 patients.
Topics: Aged; Aminolevulinic Acid; Case-Control Studies; Humans; Liver Neoplasms; Middle Aged; Porphobilinogen; Porphyria, Acute Intermittent; Porphyrins | 2023 |