ponasterone a has been researched along with ecdysterone in 153 studies
| Studies (ponasterone a) | Trials (ponasterone a) | Recent Studies (post-2010) (ponasterone a) | Studies (ecdysterone) | Trials (ecdysterone) | Recent Studies (post-2010) (ecdysterone) |
|---|---|---|---|---|---|
| 162 | 0 | 24 | 1,830 | 10 | 560 |
| Protein | Taxonomy | ponasterone a (IC50) | ecdysterone (IC50) |
|---|---|---|---|
| Ultraspiracle | Nezara viridula (southern green stink bug) | 2.849 | |
| 20-hydroxy-ecdysone receptor | Nezara viridula (southern green stink bug) | 2.849 | |
| Ecdysone receptor | Lucilia cuprina (Australian sheep blowfly) | 5.5 | |
| Protein ultraspiracle | Drosophila melanogaster (fruit fly) | 0.0457 | |
| Ecdysone receptor | Drosophila melanogaster (fruit fly) | 0.0457 | |
| Ultraspiracle | Leptinotarsa decemlineata (Colorado potato beetle) | 0.4365 | |
| 20-hydroxy-ecdysone receptor | Leptinotarsa decemlineata (Colorado potato beetle) | 0.4365 | |
| Ultraspiracle protein | Spodoptera frugiperda (fall armyworm) | 0.166 | |
| 20-hydroxy-ecdysone receptor | Spodoptera frugiperda (fall armyworm) | 0.166 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (9.15) | 18.7374 |
| 1990's | 16 (10.46) | 18.2507 |
| 2000's | 92 (60.13) | 29.6817 |
| 2010's | 30 (19.61) | 24.3611 |
| 2020's | 1 (0.65) | 2.80 |
| Authors | Studies |
|---|---|
| Akamatsu, M; Harada, T; Miyagawa, H; Nakagawa, Y | 1 |
| Birru, W; Fernley, RT; Graham, LD; Grusovin, J; Hill, RJ; Hofmann, A; Howell, L; James, PJ; Jarvis, KE; Johnson, WM; Jones, DA; Leitner, C; Liepa, AJ; Lovrecz, GO; Lu, L; Nearn, RH; O'Driscoll, BJ; Phan, T; Pollard, M; Turner, KA; Winkler, DA | 1 |
| Graham, LD; Hannan, GN; Hill, RJ; Lawrence, MC; Simpson, AM; Tohidi-Esfahani, D | 1 |
| Báthori, M; Béni, Z; Hunyadi, A; Martins, A; Molnár, J; Tóth, N; Ványolós, A; Zupkó, I | 1 |
| Chang, FR; Chen, SR; Cheng, YB; Hu, HC; Lee, JC; Lo, IW; Wu, YC; Wu, YH | 1 |
| McCarthy, JF | 1 |
| Hikino, H; Oizumi, Y; Takemoto, T | 1 |
| Bidmon, HJ; Stumpf, WE; Ueno, M | 1 |
| Nakanishi, K | 1 |
| Fahrbach, SE | 1 |
| Bidmon, HJ; Stumpf, WE | 1 |
| Bidmon, HJ | 1 |
| Spindler, KD; Spindler-Barth, M; Turberg, A | 1 |
| Bidmon, HJ; Granger, NA; Stumpf, WE | 1 |
| Kiltz, HH; Ozyhar, A; Pongs, O | 1 |
| Fahrbach, SE; Truman, JW | 1 |
| Lee, SS; Nakanishi, K | 1 |
| Grossmann, D; Spindler, KD | 1 |
| Wing, KD | 1 |
| Hétru, C; Lachaise, F; Lafont, R; Meister, MF | 1 |
| Farquharson, TE; Gilgan, MW | 1 |
| Beckers, C; Dennis, R; Emmerich, H; Maróy, P; O'Connor, JD | 1 |
| Lachaise, F; Lafont, R | 1 |
| Bonner, JJ | 1 |
| O'Connor, JD; Sage, BA; Tanis, MA | 1 |
| Hoffmann, JA; Lachaise, F | 1 |
| Goudeau, M; Hetru, C; Hoffmann, JA; Kappler, C; Lachaise, F | 1 |
| Kaufman, WR; Mao, H; McBlain, WA | 1 |
| Mikitani, K | 1 |
| Dhadialla, TS; Tzertzinis, G | 1 |
| Alnemri, ES; Gilbert, LI; Litwack, G; Song, Q | 1 |
| Blake, SM; Dawson, CW; Eliopoulos, AG; Gallagher, NJ; Young, LS | 1 |
| Mays, D; Pietenpol, JA; Stewart, ZA | 1 |
| Dunlop, J; Lou, Z; McIlvain, HB | 1 |
| Barnouin, K; Du, MQ; Eddaoudi, A; Fredersdorf, S; Lu, X; Mittnacht, S; Pan, LX | 1 |
| Choi, DS; Sadée, W; Tolbert, L; Wang, D | 1 |
| Bianchi, V; Ferraro, P; Gallinaro, L; Hellman, U; Johansson, M; Karlsson, A; Rampazzo, C; Reichard, P | 1 |
| Daniotti, JL; Giraudo, CG; Maccioni, HJ; Martina, JA; Zurita, AR | 1 |
| Arbeitman, MN; Hogness, DS | 1 |
| Albanese, C; Bouzahzah, B; D'Amico, M; Depinho, RA; Fu, M; Link, T; Nicholson, R; Pestell, RG; Reutens, AT | 1 |
| Erickson, LJ; Kouhen, OM; Law, PY; Loh, HH; Solberg, J; Wang, W | 1 |
| Minakuchi, C; Nakagawa, Y; Ueno, T | 1 |
| Ao, Y; Ford, JM; Lopez, CD; Lu, X; Naumovski, L; O'Connor, DJ; Perez, TD; Rohde, LH | 1 |
| Albanese, C; Lane, ME; Pestell, RG; Wadler, S; Yu, B | 1 |
| Harnasch, M; Kolb, C; Kusch, J; Mueller, MS; Sadowski, T; Sedlacek, R | 1 |
| Cooper, JM; Orth, M; Schapira, AH; Taanman, JW; Tabrizi, SJ; Warner, TT; Wilkinson, JM | 1 |
| Dragneva, Y; Husmann, M; Jehnichen, P; Romahn, E | 1 |
| Banayo, E; Cho, GJ; Eshelman, B; Evans, RM; Koder, A; Nelson, MC; Saez, E | 1 |
| Angliker, H; Benjamin, D; Jost, JP; Siegmann, M; Thiry, S; Zheng, Y; Zhu, B | 1 |
| Chen, X; Dang, DT; Geiman, DE; Hamlin, G; Johns, DC; Marban, E; Sun, R; Yang, VW | 1 |
| Bourne, PC; Dinan, L; Meng, Y; Sik, V; Whiting, P | 1 |
| Bailey, R; Baldwin, WS; Klaine, S; Long, KE | 1 |
| Askari, HB; Butt, TR; Carlson, GR; Dhadialla, TS; Palli, SR; Price, L; Shaaban, S; Tran, HT | 1 |
| Dudley, C; Garcia, JA; McKnight, SL; Reick, M | 1 |
| Paulus, W; Senner, V; Sotoodeh, A | 1 |
| Benjamin, D; Jost, JP | 1 |
| Pederson, T; Yarovoi, SV | 1 |
| Bhowmick, NA; Ghiassi, M; McDonnell, M; Moses, HL; Zent, R | 1 |
| Klemm, DJ; Reusch, JE | 1 |
| Boe, R; Brustugun, OT; Doskeland, SO; Fladmark, KE; Krakstad, C; Mellgren, G; Schulman, H; Vintermyr, OK | 1 |
| Grebe, M; Spindler-Barth, M | 1 |
| Minakuchi, C; Nakagawa, Y; Takahashi, K; Ueno, T | 1 |
| Adam, G; Carton, B; Decombel, L; Smagghe, G; Tirry, L; Voigt, B | 1 |
| Harris, M; McCormick, CJ; Rowlands, DJ | 1 |
| Mellgren, RL; Xu, Y | 1 |
| Endo, Y; Fukasawa, H; Masui, A; Toya, T | 1 |
| Black, DJ; Gonzalez-Hernandez, RM; King, MC; Lee, MK; Mahadevappa, M; Swisher, EM; Warrington, JA; Welcsh, PL | 1 |
| Jankam, A; Putchakarn, S; Suksamrarn, A; Tarnchompoo, B | 1 |
| Albanese, C; Hulit, J; Pestell, RG; Sakamaki, T | 1 |
| Ang, CY; Inouye, LS; Jones, RP | 1 |
| Fujiwara, H; Makka, T; Seino, A; Sonobe, H; Tomita, S | 1 |
| Beilstein, MA; Forsberg, NE; Purintrapiban, J; Wang, MC; Xiao, YY | 1 |
| Hurd, C; Rozengurt, E | 1 |
| McCormick, F; Tetsu, O | 1 |
| Hayakawa, T; Mayumi, T; Mizuguchi, H; Xu, ZL | 1 |
| Cao, X; Deng, X; May, WS | 1 |
| Amieux, PS; Bothwell, M; Hudson, M; Kanning, KC; Schecterson, LC; Wiley, JC | 1 |
| Andressen, KW; Bruheim, S; Krobert, KA; Levy, FO | 1 |
| Albanese, C; Brownlee, M; Donehower, LA; Fu, M; Harris, EL; Hulit, J; Johns, DC; Jones, JG; Li, Z; Neumeister, P; Novikoff, PM; Pattabiraman, N; Pestell, RG; Rohan, T; Sakamaki, T; Scherer, PE; Wang, C; Whitney, KD; Wu, K; Zhou, JN | 1 |
| Kamimura, M; Minakuchi, C; Miyagawa, H; Nakagawa, Y | 1 |
| Billas, IM; Garnier, JM; Iwema, T; Mitschler, A; Moras, D; Rochel, N | 1 |
| Ball, EE; Dhadialla, TS; Hayward, DC; Kuiper, MJ; Walker, VK; Wyatt, GR; Zhou, S | 1 |
| Green, RA; Kaplan, KB | 1 |
| Bianchi, V; Fabris, S; Ferraro, P; Pontarin, G; Rampazzo, C; Reichard, P | 1 |
| Bradshaw, RA; Dhar, S; Evans, GR; Hamai, Y; Jimenez, JC; Nguyen, T; Tyson, DR | 1 |
| De Loof, A; Dunbar, SJ; Martinez, A; Poels, J; Suner, MM; Vanden Broeck, J | 1 |
| Cooper, JM; Korlipara, LV; Messmer, K; Orth, M; Schapira, AH; Tabrizi, SJ; Tomlinson, C | 1 |
| Miyagawa, H; Nakagawa, Y; Ogura, T; Watanabe, B | 1 |
| Hara, S; Shimba, S; Tezuka, M; Wada, T | 1 |
| Elmogy, M; Iwami, M; Sakurai, S | 1 |
| Fauth, T; Grebe, M; Spindler-Barth, M | 1 |
| Wang, CJ; Wang, Z; Yang, AG; Yu, CJ; Zhang, L; Zhao, J | 1 |
| Brack, AR; Kaiser, H; Kandolf, R; Küpper, JH; Meyer, RG; Meyer-Ficca, ML | 1 |
| Das, R; De Santis, ML; Hammamieh, R; Jett, M | 1 |
| Butz, NV; Campbell, CE; Gronostajski, RM | 1 |
| Breyer, RM; Hata, AN; Lybrand, TP; Marnett, LJ | 1 |
| Kishikawa, H; Minakuchi, C; Miyagawa, H; Nakagawa, Y; Ogura, T; Takahashi, K | 1 |
| Bradshaw, RA; Calvert, JW; Dhar, S; Evans, GR; McConnell, MP; Naran, S; Nguyen, T; Sundine, MJ | 1 |
| Decombel, L; Smagghe, G; Tirry, L | 1 |
| Cheung, HW; Jin, DY; Ling, MT; Tsao, SW; Wang, Q; Wang, X; Wong, YC | 1 |
| Hibi, Y; Imai, K; Itoh, M; Kajino, S; Kanazawa, S; Kobayashi, S; Ohara, H; Okamoto, T; Takahashi, N | 1 |
| Chimnoi, N; Kumpun, S; Yingyongnarongkul, BE | 1 |
| Bryant, MF; Cordeiro-Stone, M; Hanaoka, F; Heffernan, TP; Kaufmann, WK; King, NM; Luche, DD; Nikolaishvili-Feinberg, N; Simpson, DA | 1 |
| Abe-Dohmae, S; Hayashi, M; Okazaki, M; Ueda, K; Yokoyama, S | 1 |
| Chang, IY; Cho, HJ; Chung, MH; Kim, HB; Kim, MH; Lee, YS; Yoon, Y; You, HJ; Youn, CK | 1 |
| Bösser, S; Oehme, I; Zörnig, M | 1 |
| Imai, K; Kajino, S; Kobayashi, S; Okamoto, T; Shimizu, S; Takahashi, N; Tomoda, K | 1 |
| Altman, S; Kovrigina, E; Pfund, E; Yang, L | 1 |
| Asquini, T; Bottazzoli, F; Brusa, R; Diodato, E; Downey, PM; Foglia, C; Grilli, M; Lozza, G; Petrò, R; Reggiani, A | 1 |
| Ida, H; Inoue, K; Ito, Y; Lee, WL; Yamamura, Y | 1 |
| He, G; Li, Y; Song, W; Tong, Y; Zhou, W | 1 |
| Chen, GQ; Fliegauf, M; Lu, Y; Lübbert, M; Song, MG; Xu, YB; Yuan, TT | 1 |
| Carlson, GR; Dhadialla, TS; Le, D; Palli, SR; Raikhel, A | 1 |
| Billas, IM; Browning, C; Dejaegere, AP; Loch, C; Martin, E; Moras, D; Stote, RH; Wurtz, JM | 1 |
| Dong, M; Gu, YC; Huo, CH; Liang, CH; Shi, QW; Zhang, ML | 1 |
| Kostich, M; Laz, TM; Mukhopadhyay, G; Norris, ED; Salisbury, BG | 1 |
| Campbell, JS; Fausto, N; Katze, MG; Lázaro, CA; Parks, WT; Tang, W | 1 |
| Durica, D; Hopkins, PM; Washington, T | 1 |
| Arai, H; Miyagawa, H; Nakagawa, Y; Watanabe, B | 1 |
| Hori, M; Hozumi, Y; Kondo, S; Mine, M; Suzuki, K; Udono, MU; Watanabe, M; Yamauchi, M | 1 |
| Alfieri, R; Cavazzoni, A; Gobbi, G; Malinverno, C; Mirandola, P; Petronini, PG; Sponzilli, I; Vitale, M | 1 |
| Azoitei, A; Spindler-Barth, M | 1 |
| Djakiew, D; Khwaja, FS; Posey, I; Wynne, S | 1 |
| Chung, JS | 1 |
| Dinan, L; Lapenna, S | 1 |
| Arora, A; Berthoud, VM; Beyer, EC; Ebihara, L; Hunt, DM; Minogue, PJ; Moore, AT; Russell-Eggitt, I; Tong, JJ | 1 |
| Arts, EJ; Bryson, YJ; Chou, T; Delair, S; Johnston, SH; Lassen, K; Lee, B; Lobritz, MA; Nguyen, S; Posta, F | 1 |
| Chae, HW; Kim, DH; Kim, HS; Lee, SW; Lee, WJ; Oh, Y | 1 |
| Aschner, M; Bowman, AB; Erikson, KM; Jiang, H; Lee, ES; Milatovic, D; Ni, M; Yin, Z | 1 |
| Alloza, I; Hirabayashi, Y; McLaughlin, M; Quoc, HP; Scott, CJ; Vandenbroeck, K | 1 |
| Guha, S; Hurd, C; Kisfalvi, K; Rozengurt, E | 1 |
| Lambert, DG; McDonald, J | 1 |
| Fernley, RT; Graham, LD; Hill, RJ; Kotze, AC | 1 |
| Miao, S; Tao, W; Wei, X; Wu, P; Xie, H | 1 |
| Cooreman, K; De Coen, W; Parmentier, K; Rougé, P; Smagghe, G; Soin, T; Swevers, L; Verhaegen, Y | 1 |
| Bustany, S; Sola, B; Tchakarska, G | 1 |
| Dhar, S; Evans, GRD; Krichevsky, A; Rogers, JM; Scholz, T | 1 |
| Harada, T; Miyagawa, H; Nakagawa, Y; Ogura, T; Ohe, T; Yamada, Y | 1 |
| Behrendt, L; Stegeman, JJ; Tarrant, AM; Verslycke, T | 1 |
| Gonsalves, SE; Kehoe, AS; Neal, SJ; Westwood, JT | 1 |
| Acevedo, G; Baele, G; Bjelica, A; Blais, C; Bonnet, E; Cazaux, M; Christiaens, O; Clark, RM; Demeestere, K; Dermauw, W; Diaz, I; Djuranović, S; Ewer, J; Farinelli, L; Fawcett, JA; Feyereisen, R; Grbić, M; Grbić, V; Gregory, TR; Henz, SR; Hernández-Crespo, P; Hudson, SD; Hutter, JL; Iga, M; Lindquist, E; Magalhães, S; Martens, C; Martinez, M; Mathieu, J; Nagy, L; Navajas, M; Navarro, M; Ngoc, PC; Ortego, F; Osborne, EJ; Pace, RM; Pires-daSilva, A; Roch, F; Rombauts, S; Rouzé, P; Sanchez-Rodriguez, A; Schmutz, J; Smagghe, G; Sucena, É; Tirry, L; Van de Peer, Y; Van Leeuwen, T; Veenstra, JA; Velez, M; Verdon, L; Villalobos, RM; Wissler, L; Yi, SV; Zeng, J; Zhurov, V | 1 |
| Christiaens, O; Grutzmacher, AD; Rougé, P; Smagghe, G; Zimmer, PD; Zotti, MJ | 1 |
| Báthori, M; Béni, Z; Dékány, M; Simon, A; Ványolós, A | 1 |
| Chen, S; Goydos, JS; Wall, BA; Wangari-Talbot, J | 1 |
| Dong, W; Gao, X; Liang, P; Tang, B; Zhou, X | 1 |
| Christiaens, O; Cooreman, K; De Wilde, R; Janssen, CR; Rougé, P; Smagghe, G; Soin, T; Swevers, L | 1 |
| Kearns, F; Liu, C; Mehrotra, P; Mhashilkar, AS; Palli, SR; Tzertzinis, G; Unnasch, TR; Vankayala, SL; Woodcock, HL | 1 |
| Dou, W; Li, G; Liao, CY; Niu, JZ; Smagghe, G; Sun, QZ; Wang, JJ; Wei, DD; Zhang, J; Zhu, L; Zotti, M | 1 |
| Andersen, JH; Glomsaker, E; Hansen, E; Hansen, KØ; Isaksson, J | 1 |
| Bakshinskaya, D; Chen, JY; Chen, KY; Dai, W; Kwan, K; Liu, AYC; Parekh, M; Seliman, H | 1 |
| Ai, J; Ashrafi, MR; Ghahvechi-Akbari, M; Hamidieh, AA; Mohammadi, M; Mohseni, R; Nikougoftar, M; Shoae-Hassani, A | 1 |
| Chan, KM; Chan, YH; Chu, KH | 1 |
| Korai, SK; Liu, ZW; Wang, SJ; Yang, ZM; Yu, N | 1 |
2 review(s) available for ponasterone a and ecdysterone
| Article | Year |
|---|---|
An assessment of the ecdysteroid receptor of Drosophila.
Topics: Affinity Labels; Animals; Cell Nucleus; Chromosomes; Cytoplasm; Drosophila; Ecdysteroids; Ecdysterone; Invertebrate Hormones; Receptors, Steroid; Transcription, Genetic | 1982 |
Recent advances in inducible expression in transgenic mice.
Topics: Animals; Anti-Bacterial Agents; Antineoplastic Agents, Hormonal; Cell Nucleus; DNA, Complementary; Ecdysone; Ecdysterone; Gene Transfer Techniques; Genes, Reporter; Genetic Techniques; Ligands; Mice; Mice, Transgenic; Models, Genetic; Tamoxifen; Tetracycline; Time Factors | 2002 |
151 other study(ies) available for ponasterone a and ecdysterone
| Article | Year |
|---|---|
Evaluation of hydrogen bonds of ecdysteroids in the ligand-receptor interactions using a protein modeling system.
Topics: Amino Acid Sequence; Animals; Binding Sites; Computer Simulation; Drosophila melanogaster; Ecdysterone; Hydrogen Bonding; Ligands; Molecular Sequence Data; Protein Engineering; Protein Interaction Domains and Motifs; Protein Structure, Tertiary; Quantitative Structure-Activity Relationship; Receptors, Steroid; Sequence Alignment; Sequence Homology, Amino Acid | 2009 |
Synthesis, binding and bioactivity of gamma-methylene gamma-lactam ecdysone receptor ligands: advantages of QSAR models for flexible receptors.
Topics: Acetamides; Binding Sites; Computer Simulation; Ligands; Quantitative Structure-Activity Relationship; Receptors, Steroid; Recombinant Proteins; Structure-Activity Relationship | 2010 |
Isoforms of the heteropteran Nezara viridula ecdysone receptor: protein characterisation, RH5992 insecticide binding and homology modelling.
Topics: Amino Acid Sequence; Animals; Ecdysteroids; Ecdysterone; Electrophoresis, Gel, Two-Dimensional; Heteroptera; Hydrazines; Insecticides; Ligands; Mass Spectrometry; Molecular Sequence Data; Protein Binding; Protein Isoforms; Receptors, Steroid; Sequence Analysis, Protein | 2011 |
Significant activity of ecdysteroids on the resistance to doxorubicin in mammalian cancer cells expressing the human ABCB1 transporter.
Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; Doxorubicin; Drug Antagonism; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Drug Synergism; Ecdysteroids; Humans; Mice; Structure-Activity Relationship | 2012 |
Ecdysones from Zoanthus spp. with inhibitory activity against dengue virus 2.
Topics: Animals; Anthozoa; Antiviral Agents; Dengue Virus; Ecdysone; Structure-Activity Relationship | 2016 |
Ponasterone A: a new ecdysteroid from the embryos and serum of brachyuran crustaceans.
Topics: Animals; Brachyura; Ecdysterone; Embryo, Nonmammalian; Female; Immunoassay; Mass Spectrometry; Radioimmunoassay; Spectrophotometry, Ultraviolet | 1979 |
Steroid metabolism in Bombyx mori, I. Catabolism of ponasterone A and ecdysterone in Bombyx mori.
Topics: Animals; Bombyx; Cholestenes; Cholesterol; Chromatography, Ion Exchange; Ecdysterone; Invertebrate Hormones; Larva; Plants; Sterols | 1975 |
Ecdysteroid binding sites in gastrolith forming tissue and stomach during the molting cycle of crayfish Procambarus clarkii.
Topics: Animals; Astacoidea; Autoradiography; Binding Sites; Calculi; Ecdysteroids; Ecdysterone; Gastric Mucosa; Invertebrate Hormones; Metamorphosis, Biological; Radioligand Assay; Receptors, Steroid; Stomach; Stomach Diseases | 1992 |
Past and present studies with ponasterones, the first insect molting hormones from plants.
Topics: Animals; Crustacea; Ecdysone; Ecdysterone; History, 20th Century; Plants | 1992 |
Developmental regulation of ecdysteroid receptors in the nervous system of Manduca sexta.
Topics: Animals; Autoradiography; Ecdysterone; Ganglia; Invertebrate Hormones; Moths; Nervous System; Neuroglia; Neurons; Receptors, Steroid | 1992 |
Uptake, distribution and binding of vertebrate and invertebrate steroid hormones and time-dependence of ponasterone A binding in Calliphora vicina. Comparisons among cholesterol, corticosterone, cortisol, dexamethasone, 5 alpha-dihydrotestosterone, 1,25-d
Topics: Animals; Autoradiography; Binding Sites; Calcitriol; Cholesterol; Corticosterone; Dexamethasone; Diptera; Ecdysone; Ecdysterone; Estradiol; Hormones; Hydrocortisone; Kinetics; Neurons; Progesterone; Salivary Glands; Steroids; Testosterone | 1991 |
Developmental changes in the presence of ecdysteroid receptors in the central nervous system of third instar larvae of Sarcophaga bullata.
Topics: Animals; Autoradiography; Brain; Diptera; Ecdysterone; Larva; Receptors, Steroid | 1991 |
On the action of RH 5849, a nonsteroidal ecdysteroid agonist, on a cell line from Chironomus tentans.
Topics: Acetylcholinesterase; Animals; Binding, Competitive; Cell Line; Chironomidae; Chitin; Dose-Response Relationship, Drug; Ecdysterone; Glucosamine; Hydrazines; Insecticides; Kinetics; Receptors, Steroid | 1991 |
Ecdysteroid binding sites localized by autoradiography in the central nervous system of precommitment fifth-stadium Manduca sexta larvae.
Topics: Animals; Autoradiography; Binding Sites; Central Nervous System; Ecdysteroids; Ecdysterone; Invertebrate Hormones; Larva; Moths | 1991 |
Pyridoxal phosphate inhibits the DNA-binding activity of the ecdysteroid receptor.
Topics: Cellulose; Centrifugation, Density Gradient; Chromatography; DNA; Ecdysterone; Pyridoxal Phosphate; Receptors, Steroid; Tritium | 1990 |
Autoradiographic identification of ecdysteroid-binding cells in the nervous system of the moth Manduca sexta.
Topics: Animals; Autoradiography; Central Nervous System; Ecdysteroids; Ecdysterone; Invertebrate Hormones; Larva; Lepidoptera; Moths | 1989 |
13C-NMR assignments of some insect molting hormones.
Topics: Ecdysone; Ecdysterone; Magnetic Resonance Spectroscopy | 1989 |
Uptake and retention of moulting hormones by the integument of crayfish in vitro. III. The possible involvement of Na+/K+-ATPase.
Topics: Animals; Astacoidea; Ecdysterone; Kinetics; Ouabain; Sodium-Potassium-Exchanging ATPase | 1987 |
RH 5849, a nonsteroidal ecdysone agonist: effects on a Drosophila cell line.
Topics: Acetylcholinesterase; Animals; Binding, Competitive; Cell Differentiation; Cell Line; Drosophila; Ecdysterone; Hydrazines; Insecticides; Receptors, Steroid | 1988 |
Studies on the biosynthesis of ecdysone by the Y-organs of Carcinus maenas.
Topics: Animals; Brachyura; Cholestenones; Chromatography, High Pressure Liquid; Ecdysone; Ecdysterone; Endocrine Glands; Kinetics | 1986 |
Paper chromatographic separation of alpha-ecdysone, ecdysterone, inokosterone, makisterone A and ponasterone A.
Topics: 1-Propanol; Butanols; Cholestenes; Chromatography, Paper; Ecdysone; Ecdysterone; Invertebrate Hormones; Methods; Solvents; Sterols; Time Factors; Tritium | 1973 |
The uptake and release of ponasterone A by the Kc cell line of Drosophila melanogaster.
Topics: Cell Division; Cell Line; Cell Nucleus; Cytosol; Dose-Response Relationship, Drug; Drosophila melanogaster; Ecdysone; Ecdysterone; Kinetics; Receptors, Cell Surface; Temperature | 1980 |
Ecdysteroid metabolism in a crab: Carcinus maenas L.
Topics: Animals; Brachyura; Chromatography, High Pressure Liquid; Ecdysteroids; Ecdysterone; Hemolymph; Invertebrate Hormones; Radioimmunoassay; Seawater | 1984 |
Characterization of ecdysteroid receptors in cytosol and naive nuclear preparations of Drosophila Kc cells.
Topics: Animals; Binding, Competitive; Cell Line; Cell Nucleus; Cytosol; Drosophila melanogaster; Ecdysterone; Embryo, Nonmammalian; Kinetics; Receptors, Steroid | 1982 |
Ecdysteroids and embryonic development in the shore crab, Carcinus maenas.
Topics: Animals; Brachyura; Ecdysone; Ecdysterone; Embryo, Nonmammalian; Female; Ovum; Radioimmunoassay | 1982 |
Ecdysteroids and ovarian development in the shore crab, Carcinus maenas.
Topics: Aging; Animals; Brachyura; Cross Reactions; Ecdysone; Ecdysterone; Female; Ovary; Radioimmunoassay; Sexual Maturation | 1981 |
Some properties of the ecdysteroid receptor in the salivary gland of the ixodid tick, Amblyomma hebraeum.
Topics: Animals; Autolysis; Ecdysterone; Female; Invertebrate Hormones; Kinetics; Protein Binding; Radioligand Assay; Receptors, Steroid; Salivary Glands; Ticks | 1995 |
A new nonsteroidal chemical class of ligand for the ecdysteroid receptor 3, 5-di-tert-butyl-4-hydroxy-N-isobutyl-benzamide shows apparent insect molting hormone activities at molecular and cellular levels.
Topics: Animals; Benzamides; Binding, Competitive; Cell Division; Cell Line; Drosophila melanogaster; Ecdysterone; Gene Expression; Insect Hormones; Kinetics; Ligands; Luciferases; Radioligand Assay; Receptors, Steroid; Recombinant Fusion Proteins; Transfection | 1996 |
Characterization and partial cloning of ecdysteroid receptor from a cotton boll weevil embryonic cell line.
Topics: Animals; Cell Line; Cloning, Molecular; Coleoptera; Ecdysterone; Hydrazines; Invertebrate Hormones; Juvenile Hormones; Receptors, Steroid; Sequence Homology, Amino Acid | 1997 |
An immunophilin is a component of the insect ecdysone receptor (EcR) complex.
Topics: Animals; Antibody Specificity; Blotting, Western; Carrier Proteins; DNA-Binding Proteins; Drosophila Proteins; Ecdysone; Ecdysterone; Feedback; Heat-Shock Proteins; Hemolymph; Manduca; Receptors, Steroid; Tacrolimus Binding Proteins; Thorax; Transcription Factors | 1997 |
Activation of the p38 mitogen-activated protein kinase pathway by Epstein-Barr virus-encoded latent membrane protein 1 coregulates interleukin-6 and interleukin-8 production.
Topics: Activating Transcription Factor 2; Animals; Antigens, Viral; Binding Sites; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Cyclic AMP Response Element-Binding Protein; Ecdysterone; Enzyme Activation; Enzyme-Linked Immunosorbent Assay; Herpesvirus 4, Human; Humans; Interleukin-6; Interleukin-8; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Proteins; Rats; TNF Receptor-Associated Factor 2; Transcription Factors; Viral Matrix Proteins | 1999 |
Defective G1-S cell cycle checkpoint function sensitizes cells to microtubule inhibitor-induced apoptosis.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Carcinoma; CDC2 Protein Kinase; Colonic Neoplasms; Cyclin B; Cyclin B1; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Ecdysterone; Female; G1 Phase; Mice; Mice, Nude; Microtubules; Neoplasm Proteins; Neoplasm Transplantation; Paclitaxel; S Phase; Tumor Cells, Cultured; Vincristine | 1999 |
Steroid hormone-inducible expression of the GLT-1 subtype of high-affinity l-glutamate transporter in human embryonic kidney cells.
Topics: Amino Acid Transport System X-AG; Animals; ATP-Binding Cassette Transporters; Biological Transport; Brain; Cell Line; Cloning, Molecular; Ecdysterone; Embryo, Mammalian; Gene Expression Regulation; Glutamic Acid; Humans; Kainic Acid; Kidney; Kinetics; Rats; Recombinant Proteins; Sodium; Transfection | 1999 |
Antiproliferative function of p27kip1 is frequently inhibited in highly malignant Burkitt's lymphoma cells.
Topics: B-Lymphocytes; Burkitt Lymphoma; Carcinoma; CDC2-CDC28 Kinases; Cell Cycle; Cell Cycle Proteins; Cyclin D3; Cyclin E; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinase Inhibitor p27; Cyclin-Dependent Kinases; Cyclins; Ecdysterone; Gene Expression Regulation, Neoplastic; Hot Temperature; Humans; Lung Neoplasms; Microtubule-Associated Proteins; Neoplasm Proteins; Prognosis; Protein Kinases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Recombinant Fusion Proteins; Retinoblastoma Protein; Transfection; Tumor Cells, Cultured; Tumor Suppressor Proteins | 1999 |
Basal signaling activity of human dopamine D2L receptor demonstrated with an ecdysone-inducible mammalian expression system.
Topics: Cell Line; Dose-Response Relationship, Drug; Ecdysone; Ecdysterone; Humans; Receptors, Dopamine D2; Signal Transduction | 2000 |
Mammalian 5'(3')-deoxyribonucleotidase, cDNA cloning, and overexpression of the enzyme in Escherichia coli and mammalian cells.
Topics: 5'-Nucleotidase; Amino Acid Sequence; Animals; Base Sequence; Blotting, Northern; Cell Line; Cloning, Molecular; Cricetinae; DNA, Complementary; Ecdysterone; Enzyme Induction; Escherichia coli; Fibroblasts; Humans; Kinetics; Mice; Molecular Sequence Data; Nucleotidases; Phosphotransferases; Placenta; Recombinant Proteins; Sequence Homology, Amino Acid; Substrate Specificity; Time Factors | 2000 |
GM3 alpha2,8-sialyltransferase (GD3 synthase): protein characterization and sub-golgi location in CHO-K1 cells.
Topics: Animals; Blotting, Western; Chickens; CHO Cells; Cricetinae; DNA, Complementary; Ecdysterone; Epitopes; Fluorescent Antibody Technique; Gene Expression Regulation, Enzymologic; Glycosylation; Golgi Apparatus; Mannosephosphates; N-Acetylgalactosaminyltransferases; Polypeptide N-acetylgalactosaminyltransferase; Sialyltransferases; Transfection | 2000 |
Molecular chaperones activate the Drosophila ecdysone receptor, an RXR heterodimer.
Topics: Adenosine Triphosphate; Animals; Benzoquinones; Binding Sites; Carrier Proteins; Cell Line; Dimerization; DNA; DNA-Binding Proteins; Drosophila; Drosophila Proteins; Ecdysterone; HSC70 Heat-Shock Proteins; HSP70 Heat-Shock Proteins; HSP90 Heat-Shock Proteins; Humans; Lactams, Macrocyclic; Magnesium; Molecular Chaperones; Quinones; Receptors, Retinoic Acid; Receptors, Steroid; Recombinant Fusion Proteins; Retinoid X Receptors; Transcription Factors | 2000 |
Sustained mammary gland-directed, ponasterone A-inducible expression in transgenic mice.
Topics: Animals; Ecdysteroids; Ecdysterone; Gene Expression Regulation; Immunohistochemistry; Mammary Glands, Animal; Mice; Mice, Transgenic; Receptors, Retinoic Acid; Receptors, Steroid; Retinoid X Receptors; Steroids; Transcription Factors | 2000 |
Deltorphin II-induced rapid desensitization of delta-opioid receptor requires both phosphorylation and internalization of the receptor.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Amino Acid Substitution; Blotting, Western; Cell Line; Clathrin-Coated Vesicles; Down-Regulation; Ecdysterone; Endocytosis; Humans; Kinetics; Mutagenesis, Site-Directed; Oligopeptides; Phosphorylation; Receptors, Opioid, delta; Serine; Sucrose | 2000 |
Inhibition of [(3)H]ponasterone a binding by ecdysone agonists in the intact Sf-9 cell line.
Topics: Animals; Cell Line; Dose-Response Relationship, Drug; Ecdysone; Ecdysterone; Inhibitory Concentration 50; Insecticides; Juvenile Hormones; Molecular Mimicry; Spodoptera; Tritium | 2000 |
Proapoptotic p53-interacting protein 53BP2 is induced by UV irradiation but suppressed by p53.
Topics: Apoptosis; Apoptosis Regulatory Proteins; Blotting, Northern; Blotting, Western; Carrier Proteins; Cell Cycle; Cell Line; Cell Survival; DNA Damage; DNA, Complementary; Dose-Response Relationship, Radiation; Ecdysterone; Genotype; Models, Biological; Oligonucleotides, Antisense; Tetracycline; Time Factors; Transcriptional Activation; Tubulin; Tumor Suppressor Protein p53; Ultraviolet Rays | 2000 |
Downregulation of cyclin D1 alters cdk 4- and cdk 2-specific phosphorylation of retinoblastoma protein.
Topics: Blotting, Western; CDC2-CDC28 Kinases; Colonic Neoplasms; Cyclin D1; Cyclin E; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinase 6; Cyclin-Dependent Kinases; Down-Regulation; Ecdysterone; Gene Expression Regulation, Neoplastic; Genes, Reporter; Humans; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Receptors, Steroid; Retinoblastoma Protein; RNA, Antisense; RNA, Messenger; Substrate Specificity; Transcriptional Activation; Transfection; Tumor Cells, Cultured | 2000 |
The murine ortholog of matrix metalloproteinase 19: its cloning, gene organization, and expression.
Topics: 3T3 Cells; Amino Acid Sequence; Animals; Base Sequence; Cloning, Molecular; DNA; DNA, Complementary; Ecdysterone; Exons; Gene Expression; Gene Expression Regulation, Enzymologic; Genes; Humans; Immunohistochemistry; Introns; Matrix Metalloproteinases, Secreted; Metalloendopeptidases; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Regulatory Sequences, Nucleic Acid; RNA, Messenger; Sequence Alignment; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Tissue Distribution; Tumor Cells, Cultured | 2000 |
Expression of mutant alpha-synuclein causes increased susceptibility to dopamine toxicity.
Topics: alpha-Synuclein; Blotting, Western; Cell Death; Cell Line; Cell Size; Dopamine; Drug-Related Side Effects and Adverse Reactions; Ecdysterone; Gene Expression; Genetic Predisposition to Disease; Humans; Immunohistochemistry; Male; Mutation; Nerve Tissue Proteins; Neurons; Parkinson Disease; Parkinson Disease, Secondary; Synucleins; Transfection | 2000 |
Nuclear receptors modulate the interaction of Sp1 and GC-rich DNA via ternary complex formation.
Topics: Animals; Antibodies; Binding Sites; Cell Extracts; Cell Line; DNA; Drosophila melanogaster; Ecdysterone; GC Rich Sequence; Interleukin-1; Ligands; Models, Biological; Oligodeoxyribonucleotides; Promoter Regions, Genetic; Protein Binding; Protein Structure, Tertiary; Receptors, Calcitriol; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Receptors, Thyroid Hormone; Recombinant Fusion Proteins; Response Elements; Retinoid X Receptors; Sp1 Transcription Factor; Substrate Specificity; Thermodynamics; Transcription Factors; Transcriptional Activation; Transfection; Tretinoin | 2000 |
Identification of ligands and coligands for the ecdysone-regulated gene switch.
Topics: Animals; Cholestenes; Ecdysone; Ecdysteroids; Ecdysterone; Gene Expression Regulation; Humans; Ligands; Mice; Mice, Transgenic; Molecular Structure; Receptors, Retinoic Acid; Receptors, Steroid; Retinoid X Receptors; Steroids; Transcription Factors | 2000 |
Overexpression of 5-methylcytosine DNA glycosylase in human embryonic kidney cells EcR293 demethylates the promoter of a hormone-regulated reporter gene.
Topics: Azacitidine; Blotting, Southern; Cell Line; DNA Glycosylases; DNA Methylation; Ecdysterone; Enhancer Elements, Genetic; Gene Amplification; Gene Dosage; Gene Expression Regulation; Gene Silencing; Genes, Reporter; Hormones; Humans; Kidney; Macromolecular Substances; Mutation; N-Glycosyl Hydrolases; Precipitin Tests; Promoter Regions, Genetic; Receptors, Retinoic Acid; Response Elements; Retinoid X Receptors; Transcription Factors; Transfection; Transgenes; Tretinoin | 2001 |
Krüppel-like factor 4 (gut-enriched Krüppel-like factor) inhibits cell proliferation by blocking G1/S progression of the cell cycle.
Topics: Adenoviridae; Animals; Blotting, Northern; Blotting, Western; Cell Cycle; Cell Division; Cell Line; Cell Separation; CHO Cells; Cricetinae; DNA; DNA-Binding Proteins; Drosophila; Ecdysone; Ecdysterone; Fibroblasts; Flow Cytometry; G1 Phase; Humans; Kruppel-Like Factor 4; Kruppel-Like Transcription Factors; Plasmids; Promoter Regions, Genetic; S Phase; Time Factors; Transcription Factors; Transfection; Tumor Cells, Cultured | 2001 |
Identification and ecdysteroid antagonist activity of three oligostilbenes from the seeds of Carex pendula (Cyperaceae).
Topics: Animals; Biological Assay; Chromatography, High Pressure Liquid; Diptera; Drosophila melanogaster; Ecdysteroids; Ecdysterone; Lepidoptera; Magnoliopsida; Receptors, Steroid; Seeds; Species Specificity; Steroids; Stilbenes | 2001 |
Incomplete ecdysis is an indicator of ecdysteroid exposure in Daphnia magna.
Topics: Animals; Daphnia; Ecdysterone; Environmental Exposure; Fertility; Molting | 2001 |
Reconstruction of ligand-dependent transactivation of Choristoneura fumiferana ecdysone receptor in yeast.
Topics: Animals; Binding Sites; DNA; Drosophila melanogaster; Ecdysone; Ecdysterone; Escherichia coli; Gene Expression; Insect Proteins; Larva; Lepidoptera; Mice; Nuclear Receptor Coactivator 2; Plasmids; Receptors, Retinoic Acid; Receptors, Steroid; Retinoid X Receptors; Saccharomyces cerevisiae; Spodoptera; Transcription Factors; Transcriptional Activation; Transfection; Tritium | 2001 |
NPAS2: an analog of clock operative in the mammalian forebrain.
Topics: Amino Acid Sequence; Animals; ARNTL Transcription Factors; Basic Helix-Loop-Helix Transcription Factors; Biological Clocks; Blotting, Northern; Cell Cycle Proteins; Cell Line; Circadian Rhythm; CLOCK Proteins; Cloning, Molecular; Cryptochromes; Darkness; Dimerization; Drosophila Proteins; Ecdysterone; Eye Proteins; Flavoproteins; Gene Expression Regulation; Humans; In Situ Hybridization; Light; Mice; Mice, Inbred Strains; Molecular Sequence Data; Nerve Tissue Proteins; Nuclear Proteins; Oligonucleotide Array Sequence Analysis; Period Circadian Proteins; Photoreceptor Cells, Invertebrate; Prosencephalon; Receptors, G-Protein-Coupled; Trans-Activators; Transcription Factors; Transfection; Tumor Cells, Cultured | 2001 |
Regulated gene expression in glioma cells: a comparison of three inducible systems.
Topics: Animals; Dimerization; Ecdysone; Ecdysterone; Gene Expression Regulation, Neoplastic; Glioma; Protein Synthesis Inhibitors; Rats; Tetracycline; Transfection; Tumor Cells, Cultured | 2001 |
Reversal of methylation-mediated repression with short-chain fatty acids: evidence for an additional mechanism to histone deacetylation.
Topics: Animals; beta-Galactosidase; Butyric Acid; Caproates; Cell Line; Chromatin; DNA; DNA Footprinting; DNA Methylation; Drug Synergism; Ecdysterone; Fatty Acids, Volatile; Gene Expression Regulation; Gene Silencing; Histone Deacetylases; Histones; Humans; Hydroxamic Acids; Kinetics; Lac Operon; Plasmids; Promoter Regions, Genetic; Time Factors | 2001 |
Human cell lines expressing hormone regulated T7 RNA polymerase localized at distinct intranuclear sites.
Topics: Bacteriophage T7; Blotting, Western; Cell Line; Cell Nucleus; DNA-Directed RNA Polymerases; Ecdysone; Ecdysterone; Fluorescent Antibody Technique; Gene Expression; Gene Expression Regulation, Enzymologic; Hormones; Humans; Microscopy, Phase-Contrast; Nuclear Localization Signals; Plasmids; Promoter Regions, Genetic; Recombinant Fusion Proteins; Transfection; Viral Proteins | 2001 |
Integrin beta 1 signaling is necessary for transforming growth factor-beta activation of p38MAPK and epithelial plasticity.
Topics: Cell Adhesion; Cell Differentiation; Cytoplasm; DNA, Complementary; Dose-Response Relationship, Drug; Ecdysterone; Enzyme Activation; Epithelial Cells; Extracellular Matrix; Genes, Dominant; Immunoblotting; Integrin beta1; Ligands; Mesoderm; Microscopy, Fluorescence; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Phenotype; Phosphorylation; Precipitin Tests; Protein Binding; Protein Serine-Threonine Kinases; Receptor, Transforming Growth Factor-beta Type II; Receptors, Transforming Growth Factor beta; Signal Transduction; Spectrometry, Fluorescence; Time Factors; Transcriptional Activation; Transforming Growth Factor beta | 2001 |
Inhibition of cAMP-response element-binding protein activity decreases protein kinase B/Akt expression in 3T3-L1 adipocytes and induces apoptosis.
Topics: Adipocytes; Apoptosis; Cell Line; Cell Nucleus; Cyclic AMP Response Element-Binding Protein; Ecdysterone; Flow Cytometry; Gene Expression Regulation; Gene Expression Regulation, Enzymologic; Immunohistochemistry; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Transfection; Tumor Necrosis Factor-alpha | 2002 |
Ca2+/calmodulin-dependent protein kinase II is required for microcystin-induced apoptosis.
Topics: 3T3 Cells; Animals; Apoptosis; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Cells, Cultured; COS Cells; Dose-Response Relationship, Drug; Ecdysterone; Electrophoresis, Gel, Two-Dimensional; Enzyme Inhibitors; Hepatocytes; Humans; Inhibitory Concentration 50; Ionophores; Male; Mice; Microcystins; Microscopy, Fluorescence; Okadaic Acid; Peptides, Cyclic; Phosphorylation; Plasmids; Rats; Rats, Wistar; Time Factors; Transfection | 2002 |
Expression of ecdysteroid receptor and ultraspiracle from Chironomus tentans (Insecta, Diptera) in E. coli and purification in a functional state.
Topics: Acrylic Resins; Animals; Blotting, Western; Chironomidae; Chromatography, Affinity; DNA-Binding Proteins; Drosophila Proteins; Ecdysterone; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Gene Expression; Receptors, Steroid; Recombinant Fusion Proteins; Transcription Factors | 2002 |
Inhibition of [3H]ponasterone A binding by ecdysone agonists in the intact Kc cell line.
Topics: Animals; Cell Line; Drosophila; Ecdysone; Ecdysterone; Molecular Structure; Spodoptera; Tritium | 2002 |
Action of brassinosteroids in the cotton leafworm Spodoptera littoralis.
Topics: Animals; Brassinosteroids; Cholestanols; Ecdysterone; Feeding Behavior; Hydrazines; Injections; Larva; Molecular Structure; Plant Growth Regulators; Spodoptera; Steroids, Heterocyclic | 2002 |
Efficient delivery and regulable expression of hepatitis C virus full-length and minigenome constructs in hepatocyte-derived cell lines using baculovirus vectors.
Topics: Animals; Baculoviridae; Chlorocebus aethiops; COS Cells; Ecdysterone; Gene Expression Regulation, Viral; Gene Transfer Techniques; Genetic Vectors; Genome, Viral; Hepacivirus; Hepatocytes; Humans; Lac Operon; Promoter Regions, Genetic; Spodoptera; Tetracycline; Tumor Cells, Cultured; Virus Replication | 2002 |
Calpain inhibition decreases the growth rate of mammalian cell colonies.
Topics: Amino Acid Sequence; Animals; Blotting, Northern; Blotting, Western; Calcium-Binding Proteins; Calpain; Cations; Cell Adhesion; Cell Division; Cell Movement; CHO Cells; Cricetinae; DNA, Complementary; Dose-Response Relationship, Drug; Down-Regulation; Ecdysterone; Fibroblasts; Gene Expression Profiling; Humans; Mice; Molecular Sequence Data; Polymerase Chain Reaction; RNA, Messenger; Sequence Homology, Amino Acid; Time Factors; Transfection; Trypsin | 2002 |
Potent and selective partial ecdysone agonist activity of chromafenozide in Sf9 cells.
Topics: Animals; Benzopyrans; Cell Line; Dose-Response Relationship, Drug; Drosophila melanogaster; Ecdysone; Ecdysterone; Enzyme Induction; Genes, Reporter; Hydrazines; Insecticides; Lepidoptera; Luciferases; Receptors, Steroid; Species Specificity; Spodoptera; Transcription, Genetic | 2002 |
BRCA1 transcriptionally regulates genes involved in breast tumorigenesis.
Topics: BRCA1 Protein; Breast; Breast Neoplasms; Cell Division; Cell Line; Cell Transformation, Neoplastic; Cloning, Molecular; DNA, Complementary; Ecdysterone; Epithelial Cells; Female; Gene Expression Regulation; Gene Expression Regulation, Neoplastic; Genes, BRCA1; Humans; Kidney; Kinetics; Mutation; Ovarian Neoplasms; Transfection | 2002 |
Ecdysteroids from a Zoanthus sp.
Topics: Animals; Cholestenes; Chromatography, Thin Layer; Cnidaria; Ecdysone; Ecdysteroids; Ecdysterone; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Stereoisomerism; Thailand | 2002 |
Effects of PCB 30 and its hydroxylated metabolites on ecdysteroid-mediated gene expression.
Topics: Animals; Cells, Cultured; Dose-Response Relationship, Drug; Ecdysterone; Gene Expression; Gene Expression Regulation, Developmental; Genes, Reporter; Hormone Antagonists; Hydroxylation; Polychlorinated Biphenyls; Receptors, Steroid; Transfection | 2002 |
A possible role of 20-hydroxyecdysone in embryonic development of the silkworm Bombyx mori.
Topics: Animals; Bombyx; Dimerization; Ecdysteroids; Ecdysterone; Ovum; Protein Binding; Receptors, Steroid; Recombinant Fusion Proteins | 2002 |
Development of a ponasterone A-inducible gene expression system for application in cultured skeletal muscle cells.
Topics: Actins; Animals; beta-Galactosidase; Cell Differentiation; Cells, Cultured; Cytomegalovirus; Dose-Response Relationship, Drug; Ecdysterone; Gene Expression Regulation; Genetic Engineering; Muscle, Skeletal; Myoblasts; Plasmids; Promoter Regions, Genetic; Rats; Transfection | 2003 |
Uncoupling of protein kinase D from suppression of EGF-dependent c-Jun phosphorylation in cancer cells.
Topics: Ecdysterone; Epidermal Growth Factor; Humans; JNK Mitogen-Activated Protein Kinases; Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase C; Serine; Signal Transduction; Tumor Cells, Cultured | 2003 |
Proliferation of cancer cells despite CDK2 inhibition.
Topics: Benzamides; Butadienes; CDC2-CDC28 Kinases; Cell Division; Colonic Neoplasms; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinases; Cyclins; Ecdysterone; Enzyme Inhibitors; Female; G1 Phase; HeLa Cells; Humans; MAP Kinase Kinase Kinases; Models, Biological; Mutagenesis, Site-Directed; Mutation; Nitriles; Oligonucleotides, Antisense; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Retinoblastoma Protein; Tumor Cells, Cultured | 2003 |
Regulated gene expression from adenovirus vectors: a systematic comparison of various inducible systems.
Topics: Adenoviridae; Cell Line; Dimerization; Doxycycline; Ecdysterone; Gene Expression Regulation; Genetic Vectors; HeLa Cells; Humans; Luciferases; Mifepristone; Recombinant Fusion Proteins; Transfection | 2003 |
Cleavage of Bax to p18 Bax accelerates stress-induced apoptosis, and a cathepsin-like protease may rapidly degrade p18 Bax.
Topics: Animals; Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; Calpain; Caspase 3; Caspase 9; Caspases; Cathepsins; Cell Membrane; Cytochrome c Group; Ecdysterone; Endopeptidases; Etoposide; Gene Expression; HL-60 Cells; Humans; Interleukin-3; K562 Cells; Kidney; Lung Neoplasms; Mice; Mitochondria; Mutagenesis; Peptide Fragments; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; U937 Cells | 2003 |
Proteolytic processing of the p75 neurotrophin receptor and two homologs generates C-terminal fragments with signaling capability.
Topics: Amyloid Precursor Protein Secretases; Animals; Apoptosis Regulatory Proteins; Aspartic Acid Endopeptidases; Carrier Proteins; Cell Line; Ecdysterone; Endopeptidases; Enzyme Activators; Enzyme Inhibitors; Humans; Membrane Proteins; Molecular Sequence Data; NF-kappa B; Peptide Fragments; Protein Processing, Post-Translational; Protein Structure, Tertiary; Proteins; Rats; Receptor, Nerve Growth Factor; Receptors, Nerve Growth Factor; Sequence Homology, Amino Acid; Signal Transduction; TNF Receptor-Associated Factor 6; Xenopus | 2003 |
Unaltered agonist potency upon inducible 5-HT7(a) but not 5-HT4(b) receptor expression indicates agonist-independent association of 5-HT7(a) receptor and Gs.
Topics: Adenylyl Cyclases; Ecdysterone; Humans; Ligands; Models, Molecular; Receptors, Serotonin; Serotonin Receptor Agonists | 2003 |
Cyclin D1 repression of peroxisome proliferator-activated receptor gamma expression and transactivation.
Topics: 3T3 Cells; Animals; Breast; Breast Neoplasms; CCAAT-Enhancer-Binding Protein-alpha; CCAAT-Enhancer-Binding Protein-beta; Cyclin D1; Ecdysterone; Epithelial Cells; Fatty Liver; Female; Gene Expression Regulation; Humans; Mice; Mice, Mutant Strains; Mice, Transgenic; Models, Molecular; Mutation; Protein Conformation; Receptors, Cytoplasmic and Nuclear; Reference Values; Repressor Proteins; Rosiglitazone; Thiazoles; Thiazolidinediones; Transcription Factors; Transcriptional Activation | 2003 |
Binding affinity of nonsteroidal ecdysone agonists against the ecdysone receptor complex determines the strength of their molting hormonal activity.
Topics: Animals; Ecdysone; Ecdysterone; Lepidoptera; Receptors, Steroid | 2003 |
Structural adaptability in the ligand-binding pocket of the ecdysone hormone receptor.
Topics: Animals; Binding Sites; Crystallography, X-Ray; Dimerization; Dioxanes; Ecdysterone; Humans; Hydrazines; Ligands; Models, Molecular; Moths; Protein Conformation; Receptors, Steroid | 2003 |
Ligand specificity and developmental expression of RXR and ecdysone receptor in the migratory locust.
Topics: Amino Acid Sequence; Animal Migration; Animals; Binding, Competitive; Cell Nucleus; Ecdysterone; Female; Grasshoppers; Models, Molecular; Molecular Sequence Data; Protein Isoforms; Radioligand Assay; Receptors, Retinoic Acid; Receptors, Steroid; Recombinant Proteins; Response Elements; Retinoid X Receptors; Sequence Alignment; Sequence Homology, Amino Acid; Sesquiterpenes; Transcription Factors; Transcription, Genetic | 2003 |
Chromosome instability in colorectal tumor cells is associated with defects in microtubule plus-end attachments caused by a dominant mutation in APC.
Topics: Adenomatous Polyposis Coli Protein; Animals; Cell Line, Tumor; Chromosomal Instability; Chromosome Segregation; Colorectal Neoplasms; Ecdysterone; Genes, APC; Humans; Kinetochores; Mice; Microtubules; Mitosis; Mutation; Peptide Fragments; Receptors, Cytoplasmic and Nuclear; Spindle Apparatus; Tubulin | 2003 |
Mitochondrial deoxyribonucleotides, pool sizes, synthesis, and regulation.
Topics: 5'-Nucleotidase; Biological Transport; Cell Division; Cell Line; Cell Line, Tumor; Cytosol; Deoxyribonucleotides; DNA; Dose-Response Relationship, Drug; Ecdysterone; Gene Silencing; Humans; Mitochondria; Models, Biological; Phosphorylation; Plasmids; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Thymidine; Thymidine Kinase; Thymine Nucleotides; Time Factors; Transfection | 2004 |
Human embryonic kidney cells (HEK-293 cells): characterization and dose-response relationship for modulated release of nerve growth factor for nerve regeneration.
Topics: Cell Differentiation; Cell Line; Dose-Response Relationship, Drug; Ecdysterone; Enzyme-Linked Immunosorbent Assay; Genetic Engineering; Humans; In Vitro Techniques; Kidney; Nerve Growth Factor; Nerve Regeneration; Neurites; Transfection | 2004 |
Functional and comparative analysis of two distinct ecdysteroid-responsive gene expression constructs in Drosophila S2 cells.
Topics: Animals; Base Sequence; Cell Line; DNA-Binding Proteins; Dose-Response Relationship, Drug; Drosophila; Drosophila Proteins; Ecdysterone; Gene Expression Regulation; Genes, Reporter; HSP70 Heat-Shock Proteins; Insect Proteins; Luciferases; Molecular Sequence Data; Promoter Regions, Genetic; Receptors, Steroid; Transcription Factors; Transfection | 2004 |
G209A mutant alpha synuclein expression specifically enhances dopamine induced oxidative damage.
Topics: Aconitate Hydratase; Adrenergic Uptake Inhibitors; alpha-Synuclein; Blotting, Western; Cell Line; Cells, Cultured; Dopamine; Ecdysterone; Glutathione; Herbicides; Humans; Immunohistochemistry; Mutation; Nerve Tissue Proteins; Oxidative Stress; Paraquat; Reserpine; Synucleins | 2004 |
Stereoselective synthesis of (22R)- and (22S)-castasterone/ponasterone A hybrid compounds and evaluation of their molting hormone activity.
Topics: Animals; Binding, Competitive; Cell Line; Cholestanols; Dose-Response Relationship, Drug; Ecdysterone; Insect Hormones; Molecular Conformation; Receptors, Steroid; Stereoisomerism; Structure-Activity Relationship | 2004 |
EPAS1 promotes adipose differentiation in 3T3-L1 cells.
Topics: 3T3-L1 Cells; Adenoviridae; Adipocytes; Adipose Tissue; Animals; Azo Compounds; Basic Helix-Loop-Helix Transcription Factors; Biological Transport; Cell Differentiation; Cell Division; Deoxyglucose; Dose-Response Relationship, Drug; Ecdysterone; Genes, Dominant; Glucose; Glucose Transporter Type 1; Glucose Transporter Type 4; Immunoblotting; Insecta; Insulin Receptor Substrate Proteins; Ligands; Luciferases; Male; Mice; Mice, Inbred C57BL; Monosaccharide Transport Proteins; Muscle Proteins; NIH 3T3 Cells; Phosphoproteins; Phosphorylation; Promoter Regions, Genetic; RNA; Trans-Activators | 2004 |
Presence of membrane ecdysone receptor in the anterior silk gland of the silkworm Bombyx mori.
Topics: Animals; Binding Sites; Blotting, Western; Bombyx; Cell Membrane; Ecdysone; Ecdysterone; Kinetics; Membrane Proteins; Octoxynol; Polyethylene Glycols; Protein Binding; Receptors, Steroid; Solubility; Subcellular Fractions | 2004 |
Dynamic of ligand binding to Drosophila melanogaster ecdysteroid receptor.
Topics: Animals; Dimerization; DNA-Binding Proteins; Drosophila melanogaster; Drosophila Proteins; Ecdysterone; Kinetics; Ligands; Receptors, Steroid; Transcription Factors | 2004 |
[Establishment of Hela cell line inducibly expressing human active granzyme B].
Topics: Cell Proliferation; Cytoskeleton; Ecdysterone; Gene Expression Regulation, Enzymologic; Genetic Vectors; Granzymes; HeLa Cells; Humans; Immunohistochemistry; Serine Endopeptidases; Transfection | 2004 |
Comparative analysis of inducible expression systems in transient transfection studies.
Topics: Animals; Bacteriophage T7; Cell Line; Dexamethasone; DNA-Directed RNA Polymerases; Doxycycline; Ecdysone; Ecdysterone; Gene Expression Regulation, Viral; Humans; Mammary Tumor Virus, Mouse; Promoter Regions, Genetic; Transfection; Viral Proteins | 2004 |
Adipocyte-fatty acid binding protein induces apoptosis in DU145 prostate cancer cells.
Topics: Apoptosis; Carrier Proteins; Cell Line, Tumor; Ecdysterone; Fatty Acid-Binding Proteins; Gene Expression Regulation; Humans; Male; Prostatic Neoplasms; Signal Transduction; Steroids; Transfection; Transforming Growth Factor alpha; Tumor Necrosis Factor-alpha | 2004 |
Differential target gene activation by TBX2 and TBX2VP16: evidence for activation domain-dependent modulation of gene target specificity.
Topics: Binding Sites; Cell Division; Cell Line; Ecdysterone; Gene Expression Profiling; Gene Expression Regulation; Herpes Simplex Virus Protein Vmw65; Humans; Mutation; Oligonucleotide Array Sequence Analysis; Receptors, Steroid; Recombinant Fusion Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; T-Box Domain Proteins; Transcriptional Activation; Transfection | 2004 |
Structural determinants of arylacetic acid nonsteroidal anti-inflammatory drugs necessary for binding and activation of the prostaglandin D2 receptor CRTH2.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Line; Cell Movement; Cyclic AMP; Ecdysterone; Humans; Indomethacin; Kidney; Mice; Prostaglandin D2; Radioligand Assay; Receptors, Immunologic; Receptors, Prostaglandin; Recombinant Proteins; Transfection; Tritium | 2005 |
Classical and three-dimensional QSAR for the inhibition of [3H]ponasterone A binding by diacylhydrazine-type ecdysone agonists to insect Sf-9 cells.
Topics: Animals; Cell Line; Ecdysone; Ecdysterone; Hydrazines; Protein Binding; Quantitative Structure-Activity Relationship; Spodoptera; Tritium | 2005 |
Nerve growth factor expression response to induction agent booster dosing in transfected human embryonic kidney cells.
Topics: Cell Differentiation; Cell Line; Cells, Cultured; Ecdysterone; Humans; Kidney; Nerve Growth Factor; Transfection | 2005 |
Action of 24-epibrassinolide on a cell line of the beet armyworm, Spodoptera exigua.
Topics: Acetylcholinesterase; Animals; Binding, Competitive; Brassinosteroids; Cell Line; Cell Proliferation; Cholestanols; Cytoskeleton; Ecdysteroids; Ecdysterone; Hydrazines; Spodoptera; Steroids, Heterocyclic | 2005 |
Mitotic arrest deficient 2 expression induces chemosensitization to a DNA-damaging agent, cisplatin, in nasopharyngeal carcinoma cells.
Topics: Antineoplastic Agents; Apoptosis; Benzopyrans; Calcium-Binding Proteins; Caspase 3; Caspase Inhibitors; Caspases; Cell Cycle Proteins; Cell Line, Tumor; Cisplatin; DNA Damage; Ecdysterone; Enzyme Inhibitors; Humans; Mad2 Proteins; Mitosis; Nasopharyngeal Neoplasms; Nitriles; Proto-Oncogene Proteins c-bcl-2; Repressor Proteins | 2005 |
53BP2 induces apoptosis through the mitochondrial death pathway.
Topics: Apoptosis; Apoptosis Regulatory Proteins; Carrier Proteins; Caspase 9; Caspases; Cytosol; Ecdysterone; Humans; Mitochondria | 2005 |
C-25 epimeric 26-haloponasterone A: synthesis, absolute configuration and moulting activity.
Topics: Animals; Bromine; Chlorine; Cholestenes; Ecdysteroids; Ecdysterone; Fluorine; Houseflies; Hydrocarbons, Halogenated; Larva; Magnetic Resonance Spectroscopy; Mass Spectrometry; Molecular Conformation; Molecular Structure; Molting; Stereoisomerism | 2005 |
Overproduction of DNA polymerase eta does not raise the spontaneous mutation rate in diploid human fibroblasts.
Topics: Blotting, Western; Caffeine; Cell Line, Transformed; Diploidy; DNA Repair; DNA-Directed DNA Polymerase; Ecdysterone; Fibroblasts; Frameshift Mutation; Gene Dosage; Genetic Complementation Test; Genetic Variation; Humans; Hypoxanthine Phosphoribosyltransferase; Kinetics; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Ultraviolet Rays; Xeroderma Pigmentosum | 2005 |
Heterogeneity of high density lipoprotein generated by ABCA1 and ABCA7.
Topics: ATP Binding Cassette Transporter 1; ATP-Binding Cassette Transporters; Cell Line; Cholesterol; Chromatography, High Pressure Liquid; Ecdysterone; Humans; Kinetics; Lipoproteins, HDL; Transfection; Up-Regulation | 2005 |
Oncogenic H-Ras up-regulates expression of Ku80 to protect cells from gamma-ray irradiation in NIH3T3 cells.
Topics: Animals; Antigens, Nuclear; Cell Survival; DNA; DNA Damage; DNA Repair; DNA-Binding Proteins; Down-Regulation; Ecdysterone; Gamma Rays; Gene Expression Regulation; Genes, ras; Ku Autoantigen; Mice; NIH 3T3 Cells; Oligonucleotide Array Sequence Analysis; Radiation Tolerance; ras Proteins; Up-Regulation | 2005 |
Agonists of an ecdysone-inducible mammalian expression system inhibit Fas Ligand- and TRAIL-induced apoptosis in the human colon carcinoma cell line RKO.
Topics: Androstadienes; Apoptosis; Apoptosis Regulatory Proteins; bcl-X Protein; Caspase 8; Caspases; Cell Cycle; Cell Line, Tumor; Chromones; Colonic Neoplasms; Ecdysterone; Enzyme Activation; Fas Ligand Protein; Flavonoids; Gene Expression Regulation, Neoplastic; Humans; Membrane Glycoproteins; Morpholines; Oncogene Protein v-akt; Phosphatidylinositol 3-Kinases; Proliferating Cell Nuclear Antigen; Protein Kinase C; Recombinant Proteins; RNA, Messenger; Signal Transduction; TNF-Related Apoptosis-Inducing Ligand; Tumor Necrosis Factor-alpha; Tumor Necrosis Factors; Wortmannin | 2006 |
Inhibition of the 53BP2S-mediated apoptosis by nuclear factor kappaB and Bcl-2 family proteins.
Topics: Apoptosis; Apoptosis Regulatory Proteins; Benzimidazoles; Carrier Proteins; Caspase 9; Caspases; Cell Survival; Ecdysterone; Electrophoretic Mobility Shift Assay; Green Fluorescent Proteins; Humans; Models, Biological; NF-kappa B; Organic Chemicals; Pancreatic Neoplasms; Proto-Oncogene Proteins c-bcl-2; Time Factors; Tumor Cells, Cultured | 2005 |
Regulated expression of functional external guide sequences in mammalian cells using a U6 RNA polymerase III promoter.
Topics: Animals; Blotting, Western; Cell Culture Techniques; Cell Line; Clone Cells; Ecdysterone; Electrophoresis, Agar Gel; Gene Expression Regulation, Enzymologic; Humans; Kinetics; Lamin Type A; Mice; Promoter Regions, Genetic; Protein Subunits; Reverse Transcriptase Polymerase Chain Reaction; Ribonuclease P; Ribonuclease T1; RNA Polymerase III; RNA, Messenger; Transcription, Genetic | 2005 |
Ecdysone-based system for controlled inducible expression of metabotropic glutamate receptor subtypes 2, 5, and 8.
Topics: Calcium; Cell Line; Cloning, Molecular; Ecdysone; Ecdysterone; Gene Expression; GTP-Binding Protein alpha Subunits; Humans; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Transcription, Genetic | 2005 |
RUNX3 cooperates with FoxO3a to induce apoptosis in gastric cancer cells.
Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Base Sequence; Bcl-2-Like Protein 11; Binding Sites; Blotting, Western; Cell Line, Tumor; Chlorocebus aethiops; Core Binding Factor Alpha 3 Subunit; COS Cells; Ecdysone; Ecdysterone; Electrophoresis, Polyacrylamide Gel; Fibroblasts; Forkhead Box Protein O3; Forkhead Transcription Factors; Gene Expression Regulation, Neoplastic; Gene Silencing; Genes, Dominant; Humans; Immunoblotting; Luciferases; Membrane Proteins; Mice; Molecular Sequence Data; NIH 3T3 Cells; Phosphorylation; Plasmids; Promoter Regions, Genetic; Protein Binding; Proto-Oncogene Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Small Interfering; Stomach Neoplasms; Transcription, Genetic; Transfection | 2006 |
Control of APP processing and Abeta generation level by BACE1 enzymatic activity and transcription.
Topics: Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Aspartic Acid Endopeptidases; Cell Line; Dose-Response Relationship, Drug; Ecdysterone; Endopeptidases; Gene Expression Regulation, Enzymologic; Humans; Neurons; Promoter Regions, Genetic; Protein Processing, Post-Translational; RNA, Messenger; Time Factors; Transcription, Genetic | 2006 |
Inducible expression of AML1-ETO fusion protein endows leukemic cells with susceptibility to extrinsic and intrinsic apoptosis.
Topics: Antibodies, Monoclonal; Apoptosis; Blotting, Western; Camptothecin; Cell Line, Tumor; Core Binding Factor Alpha 2 Subunit; Cycloheximide; Ecdysterone; fas Receptor; Flow Cytometry; Gene Expression Profiling; Gene Expression Regulation, Leukemic; Humans; Oncogene Proteins, Fusion; Receptors, Tumor Necrosis Factor; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RUNX1 Translocation Partner 1 Protein; Sensitivity and Specificity; Time Factors; Ultraviolet Rays | 2006 |
A photoaffinity, non-steroidal, ecdysone agonist, bisacylhydrazine compound, RH-131039: characterization of binding and functional activity.
Topics: Animals; Benzamides; Binding Sites; Cell Extracts; Cells, Cultured; Drosophila; Ecdysterone; Hydrazines; Insect Proteins; Ligands; Moths; Photoaffinity Labels; Receptors, Steroid | 2007 |
Critical role of desolvation in the binding of 20-hydroxyecdysone to the ecdysone receptor.
Topics: Animals; Binding Sites; Computer Simulation; Crystallography, X-Ray; DNA-Binding Proteins; Ecdysterone; Insect Proteins; Lepidoptera; Ligands; Models, Molecular; Protein Binding; Protein Structure, Quaternary; Protein Structure, Tertiary; Receptors, Steroid; Static Electricity; Transcription Factors; Water | 2007 |
[Non-taxoid chemical constituents from leaves of Taxus mairei].
Topics: Biflavonoids; Diterpenes; Ecdysterone; Furans; Lignans; Plant Leaves; Plants, Medicinal; Taxus | 2007 |
Inducible expression and pharmacological characterization of the mouse metabotropic glutamate 5b receptor.
Topics: Amino Acid Sequence; Animals; Calcium; Cell Line; Cloning, Molecular; Ecdysterone; Gene Expression Regulation; Humans; Mice; Molecular Sequence Data; Quisqualic Acid; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Species Specificity | 2008 |
Responses of nontransformed human hepatocytes to conditional expression of full-length hepatitis C virus open reading frame.
Topics: Apoptosis; Cell Adhesion; Cell Cycle; Cell Proliferation; Cell Survival; Ecdysterone; Extracellular Matrix; fas Receptor; Gene Expression; Glutamate-Cysteine Ligase; Hepacivirus; Hepatocytes; Humans; Immunity, Innate; NF-kappa B; Oligonucleotide Array Sequence Analysis; Open Reading Frames; Oxidative Stress; Polyproteins; Transcription, Genetic; Up-Regulation; Viral Proteins | 2007 |
RXR isoforms and endogenous retinoids in the fiddler crab, Uca pugilator.
Topics: Alitretinoin; Alternative Splicing; Animals; Binding Sites; Brachyura; Dimerization; Ecdysterone; Fatty Acids, Unsaturated; Kinetics; Ligands; Protein Isoforms; Protein Structure, Quaternary; Protein Subunits; Receptors, Steroid; Recombinant Proteins; Retinoid X Receptors; Retinoids; Signal Transduction; Tretinoin | 2008 |
Synthesis of ponasterone A derivatives with various steroid skeleton moieties and evaluation of their binding to the ecdysone receptor of Kc cells.
Topics: Animals; Cells, Cultured; Drosophila; Ecdysterone; Molecular Structure; Receptors, Steroid; Steroids; Structure-Activity Relationship | 2008 |
Establishment of ponasterone A-inducible the wild-type p53 protein-expressing clones from HSC-1 cells, cell growth suppression by p53 expression and the suppression mechanism.
Topics: Carcinoma; Cell Division; Cell Line, Tumor; Cellular Senescence; Ecdysterone; Feasibility Studies; Gene Expression; Genetic Therapy; Genetic Vectors; Humans; Plasmids; Skin Neoplasms; Transfection; Tumor Suppressor Protein p53 | 2009 |
TRAIL-induced apoptosis of FHIT-negative lung cancer cells is inhibited by FHIT re-expression.
Topics: Acid Anhydride Hydrolases; Apoptosis; Cell Line, Tumor; Ecdysterone; Epithelial Cells; Humans; Lung Neoplasms; Neoplasm Proteins; Receptors, TNF-Related Apoptosis-Inducing Ligand; RNA, Small Interfering; TNF-Related Apoptosis-Inducing Ligand; X-Linked Inhibitor of Apoptosis Protein | 2009 |
DNA affects ligand binding of the ecdysone receptor of Drosophila melanogaster.
Topics: Animals; Binding Sites; DNA; DNA-Binding Proteins; Drosophila melanogaster; Drosophila Proteins; Ecdysterone; Ligands; Protein Binding; Protein Multimerization; Receptors, Steroid; Response Elements; Transcription Factors | 2009 |
3,3'-diindolylmethane induction of p75NTR-dependent cell death via the p38 mitogen-activated protein kinase pathway in prostate cancer cells.
Topics: 3T3 Cells; Adenocarcinoma; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Apoptosis; Brassicaceae; Breast Neoplasms; Cell Line, Tumor; Ecdysterone; Female; Humans; Indoles; Male; Mice; Neoplasm Proteins; Nerve Tissue Proteins; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Prostatic Neoplasms; Protein Processing, Post-Translational; Receptors, Nerve Growth Factor; Recombinant Fusion Proteins; RNA, Small Interfering; Signal Transduction; Transfection | 2009 |
Hemolymph ecdysteroids during the last three molt cycles of the blue crab, Callinectes sapidus: quantitative and qualitative analyses and regulation.
Topics: Animals; Arthropod Proteins; Brachyura; Ecdysone; Ecdysterone; Hemolymph; Invertebrate Hormones; Life Cycle Stages; Molting; Nerve Tissue Proteins | 2010 |
HPLC and TLC characterisation of ecdysteroid alkyl ethers.
Topics: Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Ecdysteroids; Ecdysterone | 2009 |
A mutant connexin50 with enhanced hemichannel function leads to cell death.
Topics: Animals; Apoptosis; Cataract; Cell Culture Techniques; Child, Preschool; Connexins; Ecdysterone; Eye Proteins; Female; Flow Cytometry; Fluorescent Antibody Technique, Indirect; Gap Junctions; Gene Expression Regulation; HeLa Cells; Humans; Immunoblotting; Oocytes; Patch-Clamp Techniques; Point Mutation; Polymerase Chain Reaction; Transfection; Xenopus laevis | 2009 |
A quantitative affinity-profiling system that reveals distinct CD4/CCR5 usage patterns among human immunodeficiency virus type 1 and simian immunodeficiency virus strains.
Topics: Affinity Labels; Animals; CD4 Antigens; Cell Line; Ecdysterone; HIV-1; Humans; Mathematical Concepts; Minocycline; Receptors, CCR5; Recombinant Fusion Proteins; Simian Immunodeficiency Virus; Virus Internalization | 2009 |
Insulin-like growth factor binding protein-3 induces G1 cell cycle arrest with inhibition of cyclin-dependent kinase 2 and 4 in MCF-7 human breast cancer cells.
Topics: Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cyclin D1; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinase Inhibitor Proteins; Ecdysterone; Female; G1 Phase; Gene Expression Regulation, Neoplastic; Humans; Insulin-Like Growth Factor Binding Protein 3; Insulin-Like Growth Factor Binding Proteins; RNA, Messenger | 2010 |
Ferroportin is a manganese-responsive protein that decreases manganese cytotoxicity and accumulation.
Topics: Analysis of Variance; Animals; Cation Transport Proteins; Cell Line, Transformed; Cerebellum; Cerebral Cortex; Disease Models, Animal; Dose-Response Relationship, Drug; Ecdysterone; Female; Gene Expression Regulation; Glutamic Acid; Green Fluorescent Proteins; Humans; Intracellular Space; Manganese; Manganese Poisoning; Mice; Mice, Inbred C57BL; Transfection | 2010 |
Inhibition of secretion of interleukin (IL)-12/IL-23 family cytokines by 4-trifluoromethyl-celecoxib is coupled to degradation via the endoplasmic reticulum stress protein HERP.
Topics: Animals; Celecoxib; Cell Line; Cycloheximide; Cyclooxygenase 2 Inhibitors; Ecdysterone; Endoplasmic Reticulum; Endoplasmic Reticulum Chaperone BiP; Gene Expression Regulation; Heat-Shock Proteins; Humans; Interleukin-12; Interleukin-23; Membrane Proteins; Molecular Chaperones; Protein Subunits; Protein Synthesis Inhibitors; Pyrazoles; RNA, Small Interfering; Sulfonamides | 2010 |
Induced overexpression of protein kinase D1 stimulates mitogenic signaling in human pancreatic carcinoma PANC-1 cells.
Topics: Carcinoma; Cell Count; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; DNA; DNA Replication; Ecdysterone; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Growth Substances; Humans; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase 4; Neurotensin; Pancreatic Neoplasms; Phosphorylation; Protein Kinase C; Signal Transduction | 2010 |
Binding of GTPgamma[35S] is regulated by GDP and receptor activation. Studies with the nociceptin/orphanin FQ receptor.
Topics: Animals; Cell Membrane; Cerebral Cortex; CHO Cells; Cricetinae; Cricetulus; Ecdysterone; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Humans; Ligands; Naloxone; Nociceptin Receptor; Protein Binding; Radioligand Assay; Rats; Receptors, Opioid; Sulfur Radioisotopes | 2010 |
An ortholog of the ecdysone receptor protein (EcR) from the parasitic nematode Haemonchus contortus.
Topics: Amino Acid Sequence; Animals; Binding Sites; Brugia malayi; Cloning, Molecular; Cluster Analysis; Conserved Sequence; Dimerization; DNA, Complementary; DNA, Helminth; Ecdysterone; Haemonchus; Helminth Proteins; Insecta; Molecular Sequence Data; Phylogeny; Polymorphism, Genetic; Protein Structure, Tertiary; Receptors, Steroid; Recombinant Proteins; Sequence Alignment; Sequence Analysis, DNA | 2010 |
Phytoecdysteroids from the rhizomes of Brainea insignis.
Topics: Drugs, Chinese Herbal; Ecdysterone; Glucosides; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Rhizome | 2010 |
The brown shrimp (Crangon crangon L.) ecdysteroid receptor complex: cloning, structural modeling of the ligand-binding domain and functional expression in an EcR-deficient Drosophila cell line.
Topics: Amino Acid Sequence; Animals; Cell Line; Crangonidae; Drosophila; Ecdysterone; Molecular Sequence Data; Phylogeny; Protein Structure, Secondary; Receptors, Steroid; Retinoid X Receptors; Sequence Homology, Amino Acid | 2010 |
Cyclin D1 regulates p27(Kip1) stability in B cells.
Topics: Animals; Cell Line; Cyclin D1; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinase Inhibitor p27; Ecdysterone; G1 Phase; Mice; Phosphorylation; Precursor Cells, B-Lymphoid; Protein Stability; RNA Interference; RNA, Small Interfering; S Phase | 2011 |
Inducible nerve growth factor delivery for peripheral nerve regeneration in vivo.
Topics: Animals; Antiviral Agents; Axons; Dose-Response Relationship, Drug; Drug Delivery Systems; Ecdysterone; Ganciclovir; HEK293 Cells; Humans; Nerve Growth Factor; Nerve Regeneration; Neural Conduction; Peripheral Nerves; Rats; Rats, Nude; Sciatic Nerve; Tissue Engineering | 2010 |
Virtual screening for ligands of the insect molting hormone receptor.
Topics: Amino Acid Sequence; Animals; Cell Line; Computational Biology; Databases, Factual; Drosophila melanogaster; Drug Design; Drug Evaluation, Preclinical; Ecdysone; Ecdysterone; Genes, Reporter; HSP27 Heat-Shock Proteins; Insect Proteins; Ligands; Models, Molecular; Molecular Sequence Data; Protein Conformation; Receptors, Steroid; Reproducibility of Results; Spodoptera; User-Computer Interface | 2011 |
Ecdysteroid receptor from the American lobster Homarus americanus: EcR/RXR isoform cloning and ligand-binding properties.
Topics: Animals; Ecdysterone; Hydrazines; Nephropidae; Phthalic Acids; Polychlorinated Biphenyls; Protein Isoforms; Receptors, Steroid | 2011 |
Genome-wide examination of the transcriptional response to ecdysteroids 20-hydroxyecdysone and ponasterone A in Drosophila melanogaster.
Topics: Animals; Drosophila melanogaster; Ecdysterone; Oligonucleotide Array Sequence Analysis; Protein Isoforms; Receptors, Steroid; Salivary Glands; Transcription, Genetic | 2011 |
The genome of Tetranychus urticae reveals herbivorous pest adaptations.
Topics: Adaptation, Physiological; Animals; Ecdysterone; Evolution, Molecular; Fibroins; Gene Expression Regulation; Gene Transfer, Horizontal; Genes, Homeobox; Genome; Genomics; Herbivory; Molecular Sequence Data; Molting; Multigene Family; Nanostructures; Plants; Silk; Tetranychidae; Transcriptome | 2011 |
Sequencing and structural homology modeling of the ecdysone receptor in two chrysopids used in biological control of pest insects.
Topics: Amino Acid Sequence; Animals; Binding Sites; Computational Biology; Ecdysone; Ecdysterone; Hydrazines; Insecta; Insecticides; Juvenile Hormones; Molecular Conformation; Molecular Sequence Data; Pest Control, Biological; Receptors, Steroid | 2012 |
Novel ecdysteroids from Serratula wolffii.
Topics: Asteraceae; Chemistry, Pharmaceutical; Drug Design; Ecdysteroids; Ecdysterone; Glycosides; Magnetic Resonance Spectroscopy; Mass Spectrometry; Models, Chemical; Plant Extracts; Plant Roots; Spectrophotometry | 2012 |
Functional effects of GRM1 suppression in human melanoma cells.
Topics: Animals; Apoptosis; Cell Growth Processes; Cell Line, Tumor; Doxycycline; Ecdysterone; Gene Expression Regulation, Neoplastic; Genetic Therapy; HEK293 Cells; Humans; Immunohistochemistry; MAP Kinase Signaling System; Melanoma; Mice; Mice, Nude; Mice, Transgenic; Mitogen-Activated Protein Kinases; Oncogene Protein v-akt; Phosphatidylinositol 3-Kinases; Phosphorylation; Random Allocation; Receptors, Metabotropic Glutamate; RNA, Small Interfering; Skin Neoplasms; Xenograft Model Antitumor Assays | 2012 |
Cloning, ligand-binding, and temporal expression of ecdysteroid receptors in the diamondback moth, Plutella xylostella.
Topics: Amino Acid Sequence; Animals; Base Sequence; Cloning, Molecular; Ecdysterone; Gene Expression Regulation; Ligands; Molecular Sequence Data; Moths; Phylogeny; Protein Binding; Protein Isoforms; Protein Structure, Tertiary; Receptors, Steroid; Recombinant Proteins; Sequence Alignment | 2012 |
Cloning and functional analysis of the ecdysteroid receptor complex in the opossum shrimp Neomysis integer (Leach, 1814).
Topics: Animals; Arthropod Proteins; Cell Culture Techniques; Cloning, Molecular; Crustacea; Dimerization; Ecdysterone; Endocrine Disruptors; Environmental Exposure; Hydrazines; Insecticides; Ligands; Molecular Sequence Data; Moths; Phylogeny; Polymerase Chain Reaction; Receptors, Steroid; Retinoid X Receptors; Sequence Analysis, Protein; Sequence Analysis, RNA; Sequence Homology; Transcription Factors; Transfection | 2013 |
Identification of Ecdysone Hormone Receptor Agonists as a Therapeutic Approach for Treating Filarial Infections.
Topics: Amino Acids, Diamino; Animals; Brugia malayi; Drug Discovery; Drug Evaluation, Preclinical; Ecdysone; Ecdysterone; Filariasis; Gerbillinae; HEK293 Cells; Humans; Hydrazines; Larva; Ligands; Models, Molecular; Molecular Docking Simulation; Receptors, Steroid | 2016 |
Characterization and expression patterns of key ecdysteroid biosynthesis and signaling genes in a spider mite (Panonychus citri).
Topics: Animals; Ecdysteroids; Ecdysterone; Gene Expression Regulation, Developmental; Molting; Receptors, Steroid; RNA Interference; Signal Transduction; Tetranychidae | 2017 |
Ponasterone A and F, Ecdysteroids from the Arctic Bryozoan
Topics: Animals; Anti-Bacterial Agents; Aquatic Organisms; Arctic Regions; Bacteria; Bryozoa; Ecdysterone; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular | 2018 |
Heat shock promotes inclusion body formation of mutant huntingtin (mHtt) and alleviates mHtt-induced transcription factor dysfunction.
Topics: Animals; Cell Nucleus; Corpus Striatum; Cyclic AMP Response Element-Binding Protein; Cytosol; Ecdysterone; Embryo, Mammalian; Gene Expression Regulation; Heat Shock Transcription Factors; Heat-Shock Response; HSC70 Heat-Shock Proteins; HSP70 Heat-Shock Proteins; Huntingtin Protein; Huntington Disease; Inclusion Bodies; Models, Biological; Mutation; Neurons; NF-kappa B; PC12 Cells; Primary Cell Culture; Rats; Sorbitol | 2018 |
Overexpression of SMN2 Gene in Motoneuron-Like Cells Differentiated from Adipose-Derived Mesenchymal Stem Cells by Ponasterone A.
Topics: Adipocytes; Adolescent; Adult; Aged; Cells, Cultured; Ecdysterone; Homeobox Protein Nkx-2.2; Homeodomain Proteins; Humans; Mesenchymal Stem Cells; Middle Aged; Motor Neurons; Neurogenesis; Nuclear Proteins; Survival of Motor Neuron 2 Protein; Transcription Factors; Up-Regulation | 2019 |
Ecdysteroid-mimicking compounds act as both agonists and antagonists to the crustacean ecdysone receptor.
Topics: Animals; Binding Sites; Cell Line; Computer Simulation; Crustacea; Decapoda; Ecdysone; Ecdysteroids; Ecdysterone; Gene Expression Regulation; Genes, Reporter; Humans; Molecular Docking Simulation; Pesticides; Phylogeny; Receptors, Steroid; Retinoid X Receptors | 2019 |
Characterization of ecdysteroid biosynthesis in the pond wolf spider, Pardosa pseudoannulata.
Topics: Animals; Chromatography, Liquid; Cytochrome P-450 Enzyme System; Ecdysone; Ecdysteroids; Ecdysterone; Female; Gene Expression Regulation, Developmental; Genes, Insect; Insect Proteins; Metamorphosis, Biological; Molting; Ovary; Phylogeny; RNA Interference; Spiders; Tandem Mass Spectrometry | 2021 |