ponalrestat has been researched along with zopolrestat in 3 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Aldinger, CE; Beyer, TA; Dee, MF; Larson, ER; Mylari, BL; Siegel, TW; Singleton, DH; Zembrowski, WJ | 1 |
| Bauman, JG; Dietrich, A; Gorham, BJ; Harrison, MC; Jones, LR; Kelly, JM; Malamas, M; Millen, J; Sredy, J; Wrobel, J | 1 |
| Carper, DA; Hohman, TC; Kitchen, D; Malamas, MS; Nilakantan, R; Singh, SB | 1 |
3 other study(ies) available for ponalrestat and zopolrestat
| Article | Year |
|---|---|
Novel, potent aldose reductase inhibitors: 3,4-dihydro-4-oxo-3-[[5-(trifluoromethyl)-2-benzothiazolyl] methyl]-1-phthalazineacetic acid (zopolrestat) and congeners.
Topics: Aldehyde Reductase; Animals; Benzothiazoles; Enzyme Inhibitors; Female; Humans; Indicators and Reagents; Kinetics; Lens, Crystalline; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Structure; Phthalazines; Placenta; Pregnancy; Rats; Structure-Activity Relationship; Thiazoles; X-Ray Diffraction | 1991 |
Syntheses of tolrestat analogues containing additional substituents in the ring and their evaluation as aldose reductase inhibitors. Identification of potent, orally active 2-fluoro derivatives.
Topics: Administration, Oral; Aldehyde Reductase; Animals; Cattle; Chemical Phenomena; Chemistry; Diabetes Mellitus, Experimental; Diaphragm; Galactitol; Galactose; Glycine; Lens, Crystalline; Male; Molecular Structure; Naphthalenes; Prodrugs; Rats; Rats, Inbred Strains; Sciatic Nerve | 1991 |
Molecular modeling of the aldose reductase-inhibitor complex based on the X-ray crystal structure and studies with single-site-directed mutants.
Topics: Aldehyde Reductase; Benzothiazoles; Binding Sites; Crystallography, X-Ray; Enzyme Inhibitors; Humans; Models, Molecular; Mutagenesis, Site-Directed; Phthalazines; Recombinant Proteins; Structure-Activity Relationship; Thiazoles | 2000 |