Page last updated: 2024-08-16

ponalrestat and hydantoins

ponalrestat has been researched along with hydantoins in 9 studies

Research

Studies (9)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (11.11)	18.7374
1990's	6 (66.67)	18.2507
2000's	2 (22.22)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Banfield, CR; Brazzell, RK; Chien, JY; Mayer, PR; Slattery, JT	1
Kador, PF; Sato, S	1
Kador, PF; Kinoshita, JH; Sharpless, NE	1
Bannai, C; Itakura, M; Oda, A; Yamaoka, T; Yamashita, K	1
Carper, D; Sato, S; Sugiyama, K	1
Blessing, K; Greentree, W; Inoue, J; Kador, PF; Lackner, PA; Lizak, MJ; Mori, K; Rodriguez, L; Sato, S; Secchi, EF	1
Kador, PF; Lee, YS; Sato, S; Sugiyama, K	1
Chen, Z; Kador, PF; Lee, YS; Sugiyama, K	1
Blessing, K; Fujisawa, S; Kador, PF; Lee, JW; Lou, MF	1

Reviews

1 review(s) available for ponalrestat and hydantoins

Article	Year
Aldose reductase inhibitors: a potential new class of agents for the pharmacological control of certain diabetic complications. Journal of medicinal chemistry, 1985, Volume: 28, Issue:7 Topics: Aldehyde Reductase; Animals; Binding Sites; Blood Glucose; Cataract; Chemical Phenomena; Chemistry; Corneal Diseases; Diabetes Complications; Diabetes Mellitus; Diabetic Angiopathies; Diabetic Nephropathies; Diabetic Neuropathies; Diabetic Retinopathy; Disease Models, Animal; Fluorenes; Galactose; Humans; Hydantoins; Imidazoles; Imidazolidines; Models, Molecular; Naphthalenes; Phthalazines; Rhodanine; Sorbitol; Structure-Activity Relationship; Substrate Specificity; Sugar Alcohol Dehydrogenases; Thiazolidines; Tissue Distribution	1985

Article

Year

Aldose reductase inhibitors: a potential new class of agents for the pharmacological control of certain diabetic complications.

Journal of medicinal chemistry, 1985, Volume: 28, Issue:7

Topics: Aldehyde Reductase; Animals; Binding Sites; Blood Glucose; Cataract; Chemical Phenomena; Chemistry; Corneal Diseases; Diabetes Complications; Diabetes Mellitus; Diabetic Angiopathies; Diabetic Nephropathies; Diabetic Neuropathies; Diabetic Retinopathy; Disease Models, Animal; Fluorenes; Galactose; Humans; Hydantoins; Imidazoles; Imidazolidines; Models, Molecular; Naphthalenes; Phthalazines; Rhodanine; Sorbitol; Structure-Activity Relationship; Substrate Specificity; Sugar Alcohol Dehydrogenases; Thiazolidines; Tissue Distribution

1985

Other Studies

8 other study(ies) available for ponalrestat and hydantoins

Article	Year
Saturable tissue binding and imirestat pharmacokinetics in rats. Pharmaceutical research, 1992, Volume: 9, Issue:4 Topics: Aldehyde Reductase; Animals; Fluorenes; Hydantoins; Male; Phthalazines; Rats; Rats, Inbred Strains; Tissue Distribution	1992
Inhibition of aldehyde reductase by aldose reductase inhibitors. Biochemical pharmacology, 1990, Sep-01, Volume: 40, Issue:5 Topics: Alcohol Dehydrogenase; Aldehyde Reductase; Animals; Cells, Cultured; Fluorenes; Hydantoins; Isoquinolines; Kidney; Kinetics; Lens, Crystalline; Phthalazines; Pyridazines; Rats; Structure-Activity Relationship; Substrate Specificity; Sugar Alcohol Dehydrogenases	1990
The effect of non-enzymatic glycation on recombinant human aldose reductase. Diabetes research and clinical practice, 1995, Volume: 27, Issue:3 Topics: Aldehyde Reductase; Enzyme Inhibitors; Fluorenes; Glucose; Glycosylation; Humans; Hydantoins; Imidazoles; Imidazolidines; Kinetics; Naphthalenes; Phthalazines; Recombinant Proteins; Substrate Specificity; Transfection	1995
Aldose reductase as dihydrodiol dehydrogenase. Naphthoquinone formation by rat lens aldose reductase. Advances in experimental medicine and biology, 1997, Volume: 414 Topics: Aldehyde Reductase; Animals; Enzyme Inhibitors; Eye Proteins; Fluorenes; Hydantoins; Imidazoles; Imidazolidines; Lens, Crystalline; Naphthalenes; Naphthoquinones; Oxidoreductases; Phthalazines; Rats	1997
Effect of sorbitol dehydrogenase inhibition on sugar cataract formation in galactose-fed and diabetic rats. Experimental eye research, 1998, Volume: 67, Issue:2 Topics: Aldehyde Reductase; Animals; Cataract; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Fluorenes; Galactose; Hydantoins; L-Iditol 2-Dehydrogenase; Phthalazines; Piperazines; Pyrimidines; Rats; Rats, Sprague-Dawley	1998
Prevention of naphthalene-1,2-dihydrodiol-induced lens protein modifications by structurally diverse aldose reductase inhibitors. Experimental eye research, 1999, Volume: 68, Issue:5 Topics: Aldehyde Reductase; Animals; Cataract; Chromatography, High Pressure Liquid; Crystallins; Enzyme Inhibitors; Fluorenes; Hydantoins; Imidazoles; Imidazolidines; Lens, Crystalline; Naphthalenes; Naphthols; Naphthoquinones; Phthalazines; Rats; Spectrophotometry	1999
Isolation of a non-covalent aldose reductase-nucleotide-inhibitor complex. Biochemical pharmacology, 2000, Feb-15, Volume: 59, Issue:4 Topics: Aldehyde Reductase; Animals; Enzyme Inhibitors; Fluorenes; Humans; Hydantoins; Lens, Crystalline; Models, Molecular; Muscles; NADP; Naphthalenes; Phthalazines; Rats	2000
Relative importance of aldose reductase versus nonenzymatic glycosylation on sugar cataract formation in diabetic rats. Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2000, Volume: 16, Issue:2 Topics: Aldehyde Reductase; Animals; Cataract; Crystallins; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Fluorenes; Glutathione; Glycation End Products, Advanced; Glycosylation; Hydantoins; Lens, Crystalline; Naphthalenes; Phthalazines; Rats; Rats, Sprague-Dawley; Sorbitol; Spectrometry, Fluorescence	2000