Page last updated: 2024-09-04

pomalidomide and palbociclib

pomalidomide has been researched along with palbociclib in 2 studies

Compound Research Comparison

Studies
(pomalidomide)
Trials
(pomalidomide)
Recent Studies (post-2010)
(pomalidomide)
Studies
(palbociclib)
Trials
(palbociclib)
Recent Studies (post-2010) (palbociclib)
623121552911126864

Protein Interaction Comparison

ProteinTaxonomypomalidomide (IC50)palbociclib (IC50)
Chain B, Cell division protein kinase 6Homo sapiens (human)0.015
Chain B, Cell division protein kinase 6Homo sapiens (human)0.015
Cyclin-T1Homo sapiens (human)1.5085
Cyclin-KHomo sapiens (human)1.207
Cyclin-dependent kinase 1Homo sapiens (human)9.8
Cyclin-dependent kinase 4Homo sapiens (human)0.0109
G2/mitotic-specific cyclin-B1Homo sapiens (human)9.8
Cyclin-A2Homo sapiens (human)2.2042
AcetylcholinesteraseMus musculus (house mouse)0.021
G1/S-specific cyclin-D1Homo sapiens (human)0.0115
G1/S-specific cyclin-E1Homo sapiens (human)9.15
Cyclin-dependent kinase 2Homo sapiens (human)4.1887
G1/S-specific cyclin-D2Homo sapiens (human)0.0127
G1/S-specific cyclin-D3Homo sapiens (human)0.0194
Receptor-type tyrosine-protein kinase FLT3Homo sapiens (human)3.48
Cyclin-dependent kinase 9Homo sapiens (human)1.1821
Tyrosine-protein kinase JAK3Homo sapiens (human)0.0631
Cyclin-dependent kinase 6Homo sapiens (human)0.018

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bendjennat, M; King, HM; Kizhake, S; Kour, S; Natarajan, A; Rana, S; Zahid, M1
An, Z; Chandarlapaty, S; Deng, H; Gao, H; Li, Q; Rao, Y; Su, S; Wang, J; Wu, W; Yang, H; Yang, Z; Zhu, S1

Other Studies

2 other study(ies) available for pomalidomide and palbociclib

ArticleYear
Selective degradation of CDK6 by a palbociclib based PROTAC.
    Bioorganic & medicinal chemistry letters, 2019, 06-01, Volume: 29, Issue:11

    Topics: Cyclin-Dependent Kinase 6; Dose-Response Relationship, Drug; Humans; Models, Molecular; Molecular Structure; Piperazines; Protein Kinase Inhibitors; Proteolysis; Pyridines; Structure-Activity Relationship

2019
Potent and Preferential Degradation of CDK6 via Proteolysis Targeting Chimera Degraders.
    Journal of medicinal chemistry, 2019, 08-22, Volume: 62, Issue:16

    Topics: Angiogenesis Inhibitors; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependent Kinase 6; Hematologic Neoplasms; HL-60 Cells; Humans; Molecular Structure; Piperazines; Protein Kinase Inhibitors; Proteolysis; Pyridines; Small Molecule Libraries; Thalidomide; THP-1 Cells; Ubiquitin-Protein Ligases

2019