pomalidomide has been researched along with fluvoxamine in 2 studies
| Studies (pomalidomide) | Trials (pomalidomide) | Recent Studies (post-2010) (pomalidomide) | Studies (fluvoxamine) | Trials (fluvoxamine) | Recent Studies (post-2010) (fluvoxamine) |
|---|---|---|---|---|---|
| 623 | 121 | 552 | 2,051 | 518 | 434 |
| Protein | Taxonomy | pomalidomide (IC50) | fluvoxamine (IC50) |
|---|---|---|---|
| D | Rattus norvegicus (Norway rat) | 0.54 | |
| D(3) dopamine receptor | Rattus norvegicus (Norway rat) | 0.54 | |
| D(1B) dopamine receptor | Rattus norvegicus (Norway rat) | 0.54 | |
| D(4) dopamine receptor | Rattus norvegicus (Norway rat) | 0.54 | |
| Sodium-dependent serotonin transporter | Homo sapiens (human) | 0.0038 | |
| Sodium-dependent serotonin transporter | Rattus norvegicus (Norway rat) | 0.54 | |
| D(2) dopamine receptor | Rattus norvegicus (Norway rat) | 0.54 | |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | 3.1 | |
| Transporter | Rattus norvegicus (Norway rat) | 0.54 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Assaf, M; Hoffmann, M; Kasserra, C; Kumar, G; Li, Y; Liu, L; Palmisano, M; Wang, X | 1 |
| Hoffmann, M; Li, Y; Liu, L; Palmisano, M; Reyes, J; Wang, X; Zhang, C; Zhou, S | 1 |
2 trial(s) available for pomalidomide and fluvoxamine
| Article | Year |
|---|---|
Pomalidomide: evaluation of cytochrome P450 and transporter-mediated drug-drug interaction potential in vitro and in healthy subjects.
Topics: Adult; Angiogenesis Inhibitors; Animals; Carbamazepine; Cell Line; Cytochrome P-450 Enzyme System; Drug Interactions; Fluvoxamine; Healthy Volunteers; HEK293 Cells; Humans; Ketoconazole; Male; Membrane Transport Proteins; Middle Aged; Neoplasm Proteins; Swine; Thalidomide; Young Adult | 2015 |
In Vivo Assessment of the Effect of CYP1A2 Inhibition and Induction on Pomalidomide Pharmacokinetics in Healthy Subjects.
Topics: Adult; Aged; Area Under Curve; Caffeine; Cigarette Smoking; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1A2 Inducers; Cytochrome P-450 CYP1A2 Inhibitors; Drug Interactions; Fluvoxamine; Half-Life; Healthy Volunteers; Humans; Male; Middle Aged; Thalidomide | 2018 |